Countermeasures against space flight related bone loss.

This paper reviews human data concerning bone loss and attempted countermeasures during spaceflight and bed rest, a commonly employed technique to simulate the effects of weightlessness on the musculoskeletal system.

[1]  C S Leach,et al.  A study of metabolic balance in crewmembers of Skylab IV. , 1979, Acta astronautica.

[2]  J M Vogel,et al.  Effect of prolonged bed rest on bone mineral. , 1970, Metabolism: clinical and experimental.

[3]  A. Leblanc,et al.  Can the adult skeleton recover lost bone? , 1991, Experimental Gerontology.

[4]  J M Vogel,et al.  The effect of supplemental oral phosphate on the bone mineral changes during prolonged bed rest. , 1971, The Journal of clinical investigation.

[5]  S. Hulley,et al.  Attempts to prevent disuse osteoporosis by treatment with calcitonin, longitudinal compression and supplementary calcium and phosphate. , 1973, The Journal of clinical endocrinology and metabolism.

[6]  D. R. Lockwood,et al.  Effect of the diphosphonate EHDP on bone mineral metabolism during prolonged bed rest. , 1975, The Journal of clinical endocrinology and metabolism.

[7]  A. Leblanc,et al.  Bone mineral loss and recovery after 17 weeks of bed rest , 1990, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[8]  R S Johnston,et al.  Prolonged weightlessness and calcium loss in man. , 1979, Acta astronautica.

[9]  P. Rambaut,et al.  Bone mineral measurement: Experiment M078 , 1977 .