Prevalence of COPD among symptomatic patients in a primary care setting

Abstract Objective: Spirometry is recognized as the gold standard assessment for the diagnosis of COPD. However, spirometry continues to be underused, perpetuating the underdiagnosis of COPD. The aim of this study was to evaluate the prevalence of COPD in a primary care setting in patients with a smoking history and self-reported chronic bronchitis symptoms. Research design and methods: This was a multi-center, cross-sectional study. The primary assessment was the percentage of patients with airway obstruction (post-bronchodilator FEV1/FVC ratio ≤ 0.70) compared to those without obstruction (post-bronchodilator FEV1/FVC ratio > 0.70). Results: Airflow obstruction consistent with COPD was confirmed in 26% of patients (mean age 52.9 years, FEV1 81.4% predicted and smoking history 39.8 pack-years) that reported chronic bronchitis symptoms. Airflow obstruction increased with age and smoking history. Slight or moderate dyspnea was reported by 68% of patients and the majority had not talked to their doctor about cough and continued to smoke. Limitations: Patients were evaluated at a single visit. The definition of airway obstruction used may have lead to overdiagnosis in patients aged 70 and older. Conclusion: This study confirms that many patients with COPD remain undiagnosed in the primary care setting. Evaluation of spirometry in patients with a smoking history and chronic bronchitis symptoms can aid in the diagnosis of COPD, allowing earlier treatment thereby reducing the burden of this debilitating disease. Clinical trial registration: Study code ADC109043; clinicaltrials.gov #NCT00442468.

[1]  B. Yawn,et al.  Knowledge and attitudes of family physicians coming to COPD continuing medical education , 2008, International journal of chronic obstructive pulmonary disease.

[2]  Russell Mardon,et al.  Spirometry utilization for COPD: how do we measure up? , 2007, Chest.

[3]  D. Price,et al.  COPD screening efforts in primary care: what is the yield? , 2007, Primary care respiratory journal : journal of the General Practice Airways Group.

[4]  N. Risser,et al.  Adding spirometry, carbon monoxide, and pulmonary symptom results to smoking cessation counseling , 2007, Journal of General Internal Medicine.

[5]  K. Weiss,et al.  Spirometry use in clinical practice following diagnosis of COPD. , 2006, Chest.

[6]  C. Lenfant,et al.  Global Initiative for chronic obstructive lung disease. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease , 2006 .

[7]  J. Lammers,et al.  Prevalence of undetected persistent airflow obstruction in male smokers 40-65 years old. , 2005, Family practice.

[8]  J. Hankinson,et al.  Standardisation of spirometry , 2005, European Respiratory Journal.

[9]  W. MacNee,et al.  Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper , 2004, European Respiratory Journal.

[10]  M. Decramer,et al.  Office spirometry significantly improves early detection of COPD in general practice: the DIDASCO Study. , 2004, Chest.

[11]  T. Takishima,et al.  Underdiagnosis and undertreatment of COPD in primary care settings , 2003, Respirology.

[12]  D. Mannino Chronic obstructive pulmonary disease: definition and epidemiology. , 2003, Respiratory care.

[13]  N. Chavannes,et al.  Validity of spirometric testing in a general practice population of patients with chronic obstructive pulmonary disease (COPD) , 2003, Thorax.

[14]  D. Postma,et al.  COPD: problems in diagnosis and measurement , 2003, European Respiratory Journal.

[15]  K Larsson,et al.  Not 15 but 50% of smokers develop COPD?--Report from the Obstructive Lung Disease in Northern Sweden Studies. , 2003, Respiratory medicine.

[16]  A. Buist,et al.  Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers , 2002, European Respiratory Journal.

[17]  G. Wesseling,et al.  Detecting patients at a high risk of developing chronic obstructive pulmonary disease in general practice: cross sectional case finding study , 2002, BMJ : British Medical Journal.

[18]  D. Coultas,et al.  The health impact of undiagnosed airflow obstruction in a national sample of United States adults. , 2001, American journal of respiratory and critical care medicine.

[19]  D. Tashkin,et al.  Gender bias in the diagnosis of COPD. , 2001, Chest.

[20]  T L Petty,et al.  Obstructive lung disease and low lung function in adults in the United States: data from the National Health and Nutrition Examination Survey, 1988-1994. , 2000, Archives of internal medicine.

[21]  A. Buist,et al.  Office spirometry for lung health assessment in adults: A consensus statement from the National Lung Health Education Program. , 2000, Chest.

[22]  R. George,et al.  Course and prognosis of chronic obstructive pulmonary disease. , 1999, The American journal of the medical sciences.

[23]  J. Dickinson,et al.  Screening older patients for obstructive airways disease in a semi-rural practice , 1999, Thorax.

[24]  Petty Tl Definitions, causes, course, and prognosis of chronic obstructive pulmonary disease. , 1998 .

[25]  C. van Weel,et al.  How to avoid underdiagnosed asthma/chronic obstructive pulmonary disease? , 1998, The Journal of asthma : official journal of the Association for the Care of Asthma.

[26]  C. van Weel,et al.  Association between health-related quality of life and consultation for respiratory symptoms: results from the DIMCA programme. , 1998, The European respiratory journal.

[27]  T. Petty,et al.  Definitions, causes, course, and prognosis of chronic obstructive pulmonary disease. , 1998, Respiratory care clinics of North America.

[28]  D. Postma,et al.  Risk factors for accelerated decline among patients with chronic obstructive pulmonary disease. , 1996, American journal of respiratory and critical care medicine.

[29]  J. Ware,et al.  A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. , 1996, Medical care.

[30]  M. Connolly,et al.  Prevalence and treatment of chronic airways obstruction in adults over the age of 45. , 1996, Thorax.

[31]  W. Bailey,et al.  Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study. , 1995, JAMA.

[32]  K. Chapman,et al.  Physician perceptions and management of COPD. , 1993, Chest.

[33]  N. Anthonisen Prognosis in chronic obstructive pulmonary disease: results from multicenter clinical trials. , 1989, The American review of respiratory disease.

[34]  A. Buist Standardization of spirometry. , 1987, The American review of respiratory disease.