A novel and cost effective method of removing excess albumin from plasma/serum samples and its impacts on LC-MS/MS bioanalysis of therapeutic proteins.
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[1] Irene van den Broek,et al. Bioanalytical LC-MS/MS of protein-based biopharmaceuticals. , 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[2] Ming Zhu,et al. Highly specific and sensitive measurements of human and monkey interleukin 21 using sequential protein and tryptic peptide immunoaffinity LC-MS/MS. , 2013, Analytical chemistry.
[3] Qin C Ji,et al. Liquid chromatography coupled with tandem mass spectrometry for the bioanalysis of proteins in drug development: practical considerations in assay development and validation. , 2013, Journal of chromatography. A.
[4] Hendrik Neubert,et al. Sequential protein and peptide immunoaffinity capture for mass spectrometry-based quantification of total human β-nerve growth factor. , 2013, Analytical chemistry.
[5] Hossein Salimi-Moosavi,et al. Simultaneous Analysis of Multiple Monoclonal Antibody Biotherapeutics by LC-MS/MS Method in Rat Plasma Following Cassette-Dosing , 2012, The AAPS Journal.
[6] Zheng Ouyang,et al. Pellet digestion: a simple and efficient sample preparation technique for LC-MS/MS quantification of large therapeutic proteins in plasma. , 2012, Bioanalysis.
[7] William S. Hancock,et al. Development of different analysis platforms with LC-MS for pharmacokinetic studies of protein drugs. , 2009, Analytical chemistry.
[8] T. Larson,et al. Quantification of urinary albumin by using protein cleavage and LC-MS/MS. , 2009, Clinical chemistry.
[9] D. Rajalingam,et al. Trichloroacetic acid‐induced protein precipitation involves the reversible association of a stable partially structured intermediate , 2009, Protein science : a publication of the Protein Society.
[10] Olivier Heudi,et al. Towards absolute quantification of therapeutic monoclonal antibody in serum by LC-MS/MS using isotope-labeled antibody standard and protein cleavage isotope dilution mass spectrometry. , 2008, Analytical chemistry.
[11] He-Hsuan Hsiao,et al. A modified protein precipitation procedure for efficient removal of albumin from serum , 2005, Electrophoresis.
[12] S. E. Michael. The isolation of albumin from blood serum or plasma by means of organic solvents. , 1962, The Biochemical journal.
[13] M. Delaville,et al. [Solubility characteristics of the albumin fraction of blood serum in ethyl alcohol acidified with trichloroacetic acid; its application to the determination of various protein fractions]. , 1954, Annales pharmaceutiques francaises.
[14] W. Hughes,et al. Preparation and Properties of Serum and Plasma Proteins. XIII. Crystallization of Serum Albumins from Ethanol-Water Mixtures1a,b , 1947 .