The use of "artificial skin" for burns.

An artificial skin composed of epidermal and dermal analogues has been successfully used in animal models and in severely burned patients. The development of skin substitutes, the clinical use of artificial skin, and future physiologic skin replacements are discussed.

[1]  N. O'connor,et al.  Cultured epithelium as a skin substitute. , 1985, Clinics in plastic surgery.

[2]  C. Compton,et al.  Permanent Coverage of Large Burn Wounds with Autologous Cultured Human Epithelium , 1984 .

[3]  J. Fisher.  Skin--the ultimate solution for the burn wound. , 1984, The New England journal of medicine.

[4]  I. Yannas,et al.  Wound tissue can utilize a polymeric template to synthesize a functional extension of skin. , 1982, Science.

[5]  J. Burke,et al.  Successful Use of a Physiologically Acceptable Artificial Skin in the Treatment of Extensive Burn Injury , 1981, Annals of surgery.

[6]  J. Mulliken,et al.  GRAFTING OF BURNS WITH CULTURED EPITHELIUM PREPARED FROM AUTOLOGOUS EPIDERMAL CELLS , 1981, The Lancet.

[7]  N. Dagalakis,et al.  Design of an artificial skin. Part III. Control of pore structure. , 1980, Journal of biomedical materials research.

[8]  I. Yannas,et al.  Design of an artificial skin. II. Control of chemical composition. , 1980, Journal of biomedical materials research.

[9]  I. Yannas,et al.  Design of an artificial skin. I. Basic design principles. , 1980, Journal of biomedical materials research.

[10]  T. Shires.  Consensus Development Conference. Supportive therapy in burn care. Concluding remarks by the chairman. , 1979, Journal of Trauma.

[11]  R. Bartlett,et al.  Current status of skin substitutes. , 1978, The Surgical clinics of North America.

[12]  Woodroof Ea.  Use of glutaraldehyde and formaldehyde to process tissue heart valves. , 1978 .

[13]  J. Ninnemann,et al.  PROLONGED SURVIVAL OF HUMAN SKIN ALLOGRAFTS FOLLOWING THERMAL INJURY , 1978, Transplantation.

[14]  R. Bartlett,et al.  Mechanism of skin graft adherence: collagen, elastin, and fibrin interactions. , 1977, Surgical forum.

[15]  J. Burke,et al.  Primary excision and prompt grafting as routine therapy for the treatment of thermal burns in children. , 1976, The Surgical clinics of North America.

[16]  P. Fleishman,et al.  Experience in the application of porcine xenografts to split-graft donor sites. , 1976, The Journal of trauma.

[17]  J. Burke,et al.  Primary burn excision and immediate grafting: a method shortening illness. , 1974, The Journal of trauma.

[18]  J. May,et al.  Temporary skin transplantation and immunosuppression for extensive burns. , 1974, The New England journal of medicine.

[19]  R. Kronenthal,et al.  Medical and surgical applications of collagen. , 1973, International review of connective tissue research.

[20]  B. Corps.  The effect of graft thickness, donor site and graft bed on graft shrinkage in the hooded rat. , 1969, British journal of plastic surgery.

[21]  W. M. Chardack,et al.  SYNTHETIC SUBSTITUTES FOR SKIN: Clinical Experience with Their Use in the Treatment of Burns , 1962, Plastic and reconstructive surgery and the transplantation bulletin.

[22]  J. Gross,et al.  Thermal reconstitution of collagen from solution and the response to its heterologous implantation. , 1962, The Journal of surgical research.

[23]  P. Russell,et al.  Studies on Wound Healing, with Special Reference to the Phenomenon of Contracture in Experimental Wounds in Rabbits' Skin* , 1956, Annals of surgery.

[24]  R. Billingham,et al.  Transplantation studies on sheets of pure epidermal epithelium and on epidermal cell suspensions. , 1952, British journal of plastic surgery.

[25]  A. Pirie,et al.  Chronic inflammation due to implanted colagen , 1942 .

[26]  J. Brown,et al.  MASSIVE REPAIRS OF BURNS WITH THICK SPLIT-SKIN GRAFTS: EMERGENCY "DRESSINGS" WITH HOMOGRAFTS. , 1942, Annals of Surgery.