Role of selection in fixation of gene duplications.

[1]  G. V. Ommen Frequency of new copy number variation in humans , 2005, Nature Genetics.

[2]  Peter D Stenson,et al.  Meta‐Analysis of gross insertions causing human genetic disease: Novel mutational mechanisms and the role of replication slippage , 2005, Human Mutation.

[3]  X. Gu,et al.  Rapid evolution of expression and regulatory divergences after yeast gene duplication. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[4]  J. Tower Developmental gene amplification and origin regulation. , 2004, Annual review of genetics.

[5]  Jeroen Raes,et al.  Duplication and divergence: the evolution of new genes and old ideas. , 2004, Annual review of genetics.

[6]  Wen-Hsiung Li,et al.  Different age distribution patterns of human, nematode, and Arabidopsis duplicate genes. , 2004, Gene.

[7]  Hideki Innan,et al.  Very Low Gene Duplication Rate in the Yeast Genome , 2004, Science.

[8]  P. Klatt,et al.  Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging. , 2004, Genes & development.

[9]  Matthew Meyerson,et al.  Somatic alterations in the human cancer genome. , 2004, Cancer cell.

[10]  M. Lynch,et al.  The altered evolutionary trajectories of gene duplicates. , 2004, Trends in genetics : TIG.

[11]  E. Lander,et al.  Finishing the euchromatic sequence of the human genome , 2004 .

[12]  Stylianos E. Antonarakis,et al.  Chromosome 21 and Down syndrome: from genomics to pathophysiology , 2004, Nature Reviews Genetics.

[13]  P. Green,et al.  Bayesian Markov chain Monte Carlo sequence analysis reveals varying neutral substitution patterns in mammalian evolution. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[14]  A Dürr,et al.  Causal relation between α-synuclein locus duplication as a cause of familial Parkinson's disease , 2004, The Lancet.

[15]  Philippe Amouyel,et al.  α-synuclein locus duplication as a cause of familial Parkinson's disease , 2004, The Lancet.

[16]  A. Singleton,et al.  Parkinson's disease and dementia with Lewy bodies: a difference in dose? , 2004, The Lancet.

[17]  Wen-Hsiung Li,et al.  Patterns of segmental duplication in the human genome. , 2004, Molecular biology and evolution.

[18]  L. Feuk,et al.  Detection of large-scale variation in the human genome , 2004, Nature Genetics.

[19]  J. Wienberg,et al.  The evolutionary history of human chromosome 7. , 2004, Genomics.

[20]  Shishir Shah,et al.  Genome-wide array comparative genomic hybridization analysis reveals distinct amplifications in osteosarcoma , 2004, BMC Cancer.

[21]  N. Freimer,et al.  A genome-wide survey of segmental duplications that mediate common human genetic variation of chromosomal architecture , 2004, Human Genomics.

[22]  T. Hulsebos,et al.  Amplification and overexpression of genes in 17p11.2 ~ p12 in osteosarcoma. , 2004, Cancer genetics and cytogenetics.

[23]  Aleksey Y Ogurtsov,et al.  Indel-based evolutionary distance and mouse-human divergence. , 2004, Genome research.

[24]  R. Price,et al.  Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number , 2004, The Lancet.

[25]  Kenny Q. Ye,et al.  Large-Scale Copy Number Polymorphism in the Human Genome , 2004, Science.

[26]  Nathan Srebro,et al.  Distribution of short paired duplications in mammalian genomes. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[27]  Eugene V Koonin,et al.  Duplicated genes evolve slower than singletons despite the initial rate increase , 2004, BMC Evolutionary Biology.

[28]  Eugene V Koonin,et al.  A common framework for understanding the origin of genetic dominance and evolutionary fates of gene duplications. , 2004, Trends in genetics : TIG.

[29]  Janet Hemingway,et al.  The molecular basis of insecticide resistance in mosquitoes. , 2004, Insect biochemistry and molecular biology.

[30]  C. Pál,et al.  Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast , 2004, Nature.

[31]  L. Hurst,et al.  Similar rates but different modes of sequence evolution in introns and at exonic silent sites in rodents: evidence for selectively driven codon usage. , 2004, Molecular biology and evolution.

[32]  O. Duron,et al.  Insecticide resistance genes confer a predation cost on mosquitoes, Culex pipiens. , 2004, Genetical research.

[33]  Steven B Cannon,et al.  The roles of segmental and tandem gene duplication in the evolution of large gene families in Arabidopsis thaliana , 2004, BMC Plant Biology.

[34]  David W. Miller,et al.  α-Synuclein in blood and brain from familial Parkinson disease with SNCA locus triplication , 2004, Neurology.

[35]  Keith W. Jones,et al.  Whole genome DNA copy number changes identified by high density oligonucleotide arrays , 2004, Human Genomics.

[36]  E. Eichler,et al.  Analysis of segmental duplications and genome assembly in the mouse. , 2004, Genome research.

[37]  B. Birren,et al.  Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae , 2004, Nature.

[38]  R. Palmiter Protection against zinc toxicity by metallothionein and zinc transporter 1. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[39]  Manyuan Long,et al.  Duplication-degeneration as a mechanism of gene fission and the origin of new genes in Drosophila species , 2004, Nature Genetics.

[40]  J. Lupski,et al.  Implications of human genome architecture for rearrangement-based disorders: the genomic basis of disease. , 2004, Human molecular genetics.

[41]  D. Gevers,et al.  Gene duplication and biased functional retention of paralogs in bacterial genomes. , 2004, Trends in microbiology.

[42]  E. Eichler,et al.  BAC microarray analysis of 15q11–q13 rearrangements and the impact of segmental duplications , 2004, Journal of Medical Genetics.

[43]  T. Hubbard,et al.  A census of human cancer genes , 2004, Nature Reviews Cancer.

[44]  D. Petrov,et al.  Preferential Duplication of Conserved Proteins in Eukaryotic Genomes , 2004, PLoS biology.

[45]  J. Inazawa,et al.  Alteration in Copy Numbers of Genes as a Mechanism for Acquired Drug Resistance , 2004, Cancer Research.

[46]  Shen Hu,et al.  Detection of DNA copy number abnormality by microarray expression analysis , 2004, Human Genetics.

[47]  M. Shapero,et al.  High-resolution analysis of DNA copy number using oligonucleotide microarrays. , 2004, Genome research.

[48]  Alexey S Kondrashov,et al.  Context of deletions and insertions in human coding sequences , 2004, Human mutation.

[49]  R. Sudbrak,et al.  Plasticity of human chromosome 3 during primate evolution. , 2004, Genomics.

[50]  Matthew J. Farrer,et al.  Comparison of kindreds with parkinsonism and α‐synuclein genomic multiplications , 2004 .

[51]  B. Dujon,et al.  Eucaryotic genome evolution through the spontaneous duplication of large chromosomal segments , 2004, The EMBO journal.

[52]  M. Raymond,et al.  FITNESS COSTS OF INSECTICIDE RESISTANCE IN NATURAL BREEDING SITES OF THE MOSQUITO CULEX PIPIENS , 2004, Evolution; international journal of organic evolution.

[53]  Richard C. Moore,et al.  The early stages of duplicate gene evolution , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[54]  Laureana Rebordinos,et al.  Genome-wide amplifications caused by chromosomal rearrangements play a major role in the adaptive evolution of natural yeast. , 2003, Genetics.

[55]  M. Lynch,et al.  The structure and early evolution of recently arisen gene duplicates in the Caenorhabditis elegans genome. , 2003, Genetics.

[56]  A. Órfão,et al.  Her-2/neu gene amplification in familial vs sporadic breast cancer. Impact on the behavior of the disease. , 2003, American journal of clinical pathology.

[57]  A. Órfão,et al.  Her-2/neu Gene Amplification in Familial vs Sporadic Breast Cancer , 2003 .

[58]  Kevin R. Thornton,et al.  The origin of new genes: glimpses from the young and old , 2003, Nature Reviews Genetics.

[59]  Janel O. Johnson,et al.  α-Synuclein Locus Triplication Causes Parkinson's Disease , 2003, Science.

[60]  Daniel Pinkel,et al.  Genomic microarrays in human genetic disease and cancer. , 2003, Human molecular genetics.

[61]  E. Eichler,et al.  An Alu transposition model for the origin and expansion of human segmental duplications. , 2003, American journal of human genetics.

[62]  Z. Gu,et al.  Different evolutionary patterns between young duplicate genes in the human genome , 2003, Genome Biology.

[63]  A. Wagner,et al.  Asymmetric sequence divergence of duplicate genes. , 2003, Genome research.

[64]  C. T. Morgan,et al.  A genomic rearrangement resulting in a tandem duplication is associated with split hand-split foot malformation 3 (SHFM3) at 10q24. , 2003, Human molecular genetics.

[65]  Balázs Papp,et al.  Evolution of cis-regulatory elements in duplicated genes of yeast. , 2003, Trends in genetics : TIG.

[66]  K. Kidd,et al.  Low nucleotide diversity in chimpanzees and bonobos. , 2003, Genetics.

[67]  C. Pál,et al.  Dosage sensitivity and the evolution of gene families in yeast , 2003, Nature.

[68]  Wen-Hsiung Li,et al.  Divergence in the spatial pattern of gene expression between human duplicate genes. , 2003, Genome research.

[69]  P. Stenson,et al.  Human Gene Mutation Database (HGMD®): 2003 update , 2003, Human mutation.

[70]  L. Shaffer,et al.  Genome architecture catalyzes nonrecurrent chromosomal rearrangements. , 2003, American journal of human genetics.

[71]  H. Saal,et al.  Unexpected survival in a case of prenatally diagnosed non‐mosaic trisomy 22: Clinical report and review of the natural history , 2003, American journal of medical genetics. Part A.

[72]  Daniel Pinkel,et al.  Large-scale variation among human and great ape genomes determined by array comparative genomic hybridization. , 2003, Genome research.

[73]  Alexey S Kondrashov,et al.  Direct estimates of human per nucleotide mutation rates at 20 loci causing mendelian diseases , 2003, Human mutation.

[74]  P. Buckland,et al.  Polymorphically duplicated genes: their relevance to phenotypic variation in humans , 2003, Annals of medicine.

[75]  D. Nicolae,et al.  Rapid divergence in expression between duplicate genes inferred from microarray data. , 2002, Trends in genetics : TIG.

[76]  R. Britten,et al.  Divergence between samples of chimpanzee and human DNA sequences is 5%, counting indels , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[77]  U. Scheer,et al.  On the formation of amplified nucleoli during early Xenopus oogenesis. , 2002, Journal of structural biology.

[78]  Christian A. Rees,et al.  Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[79]  M. Adams,et al.  Recent Segmental Duplications in the Human Genome , 2002, Science.

[80]  Ronald W. Davis,et al.  Functional profiling of the Saccharomyces cerevisiae genome , 2002, Nature.

[81]  H. Philippe,et al.  Ancient phylogenetic relationships. , 2002, Theoretical population biology.

[82]  Adam Eyre-Walker,et al.  Adaptive protein evolution in Drosophila , 2002, Nature.

[83]  P. Stankiewicz,et al.  Genome architecture, rearrangements and genomic disorders. , 2002, Trends in genetics : TIG.

[84]  E. Koonin,et al.  Selection in the evolution of gene duplications , 2002, Genome Biology.

[85]  G Achaz,et al.  Study of intrachromosomal duplications among the eukaryote genomes. , 2001, Molecular biology and evolution.

[86]  Tamim H. Shaikh,et al.  Segmental duplications: an 'expanding' role in genomic instability and disease , 2001, Nature Reviews Genetics.

[87]  L. Quillet,et al.  Estimation of the abundance of the cadmium resistance gene cadA in microbial communities in polluted estuary water. , 2001, Research in microbiology.

[88]  W. Figg,et al.  The androgen receptor gene and its influence on the development and progression of prostate cancer , 2001, The Journal of pathology.

[89]  W. Ernst,et al.  Enhanced copper tolerance in Silene vulgaris (Moench) Garcke populations from copper mines is associated with increased transcript levels of a 2b-type metallothionein gene. , 2001, Plant physiology.

[90]  J. Widholm,et al.  Glyphosate selection of gene amplification in suspension cultures of 3 plant species. , 2001, Physiologia plantarum.

[91]  L. Guarente,et al.  Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans , 2001, Nature.

[92]  A. Kondrashov Sex and U. , 2001, Trends in genetics : TIG.

[93]  M. Lynch,et al.  The evolutionary fate and consequences of duplicate genes. , 2000, Science.

[94]  K. Uchida,et al.  Genome-wide profiling of gene amplification and deletion in cancer. , 2000, Human cell.

[95]  M. Nachman,et al.  Estimate of the mutation rate per nucleotide in humans. , 2000, Genetics.

[96]  C. Pál,et al.  The evolution of gene number: are heritable and non-heritable errors equally important? , 2000, Heredity.

[97]  Ash A. Alizadeh,et al.  Genome-wide analysis of DNA copy number variation in breast cancer using DNA microarrays , 1999, Nature Genetics.

[98]  M. Shy,et al.  The molecular pathogenesis of Pelizaeus-Merzbacher disease. , 1999, Archives of neurology.

[99]  M. McVey,et al.  The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. , 1999, Genes & development.

[100]  M. Ouellette,et al.  Role of the locus and of the resistance gene on gene amplification frequency in methotrexate resistant Leishmania tarentolae. , 1999, Nucleic acids research.

[101]  M. Schwab Oncogene amplification in solid tumors. , 1999, Seminars in cancer biology.

[102]  A. Force,et al.  Preservation of duplicate genes by complementary, degenerative mutations. , 1999, Genetics.

[103]  J. Lupski Charcot-Marie-Tooth Polyneuropathy: Duplication, Gene Dosage, and Genetic Heterogeneity , 1999, Pediatric Research.

[104]  T. Lenormand,et al.  APPEARANCE AND SWEEP OF A GENE DUPLICATION: ADAPTIVE RESPONSE AND POTENTIAL FOR NEW FUNCTIONS IN THE MOSQUITO CULEX PIPIENS , 1998, Evolution; international journal of organic evolution.

[105]  T. Lenormand,et al.  An overview of the evolution of overproduced esterases in the mosquito Culex pipiens. , 1998, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[106]  R. Mazzarella,et al.  Pathological consequences of sequence duplications in the human genome. , 1998, Genome research.

[107]  C. Brown,et al.  Multiple duplications of yeast hexose transport genes in response to selection in a glucose-limited environment. , 1998, Molecular biology and evolution.

[108]  M Raymond,et al.  Polymorphisms and fluctuations in copy number of amplified esterase genes in Culex pipiens mosquitoes , 1998, Insect molecular biology.

[109]  B. V. van Oost,et al.  Duplication of the proteolipid protein gene is the major cause of Pelizaeus‐Merzbacher disease , 1998, Neurology.

[110]  M. Yao,et al.  Regulatory sequences for the amplification and replication of the ribosomal DNA minichromosome in Tetrahymena thermophila , 1997, Molecular and cellular biology.

[111]  M. Raymond,et al.  Esterase gene amplification in Culex pipiens , 1997, Insect molecular biology.

[112]  R. C. Woodruff,et al.  Clusters of identical new mutations can account for the "overdispersed" molecular clock. , 1997, Genetics.

[113]  J. Cooke,et al.  Evolutionary origins and maintenance of redundant gene expression during metazoan development. , 1997, Trends in genetics : TIG.

[114]  Martin A. Nowak,et al.  Evolution of genetic redundancy , 1997, Nature.

[115]  J. Lupski,et al.  Charcot-Marie-Tooth disease and related inherited neuropathies. , 1996, Medicine.

[116]  M. Taylor,et al.  Molecular biology and evolution of resistance of toxicants. , 1996, Molecular biology and evolution.

[117]  M. Inouhe,et al.  Amplification of a gene for metallothionein by tandem repeat in a strain of cadmium-resistant yeast cells , 1996 .

[118]  L. N. Muntyan,et al.  Zinc- and arsenic-resistant strains of Thiobacillus ferrooxidans have increased copy numbers of chromosomal resistance genes. , 1995, Microbiology.

[119]  A. Kondrashov,et al.  Genotype—environment interactions and the estimation of the genomic mutation rate in Drosophila melanogaster , 1994, Proceedings of the Royal Society of London. Series B: Biological Sciences.

[120]  A. Clark,et al.  Invasion and maintenance of a gene duplication. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[121]  J. Lupski,et al.  Molecular analyses of unrelated Charcot-Marie-Tooth (CMT) disease patients suggest a high frequency of the CMTIA duplication. , 1993, American journal of human genetics.

[122]  S. Reinbothe,et al.  Overproduction by gene amplification of the multifunctional arom protein confers glyphosate tolerance to a plastid-free mutant of Euglena gracilis , 1993, Molecular and General Genetics MGG.

[123]  M. Ouellette,et al.  Mechanisms of drug resistance in Leishmania. , 1993, Parasitology today.

[124]  T. Triglia,et al.  Amplification of the multidrug resistance gene pfmdr1 in Plasmodium falciparum has arisen as multiple independent events , 1991, Molecular and cellular biology.

[125]  M. Kreitman,et al.  Adaptive protein evolution at the Adh locus in Drosophila , 1991, Nature.

[126]  B. Tabashnik Implications of gene amplification for evolution and management of insecticide resistance. , 1990, Journal of economic entomology.

[127]  A. Cowman,et al.  Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum , 1989, Cell.

[128]  E. Gaginskaya,et al.  Amplification of ribosomal genes and formation of extrachromosomal nucleoli in oocytes of starfish Henricia hayashi (Asteroidea: Echinasteridae). , 1988, Cell differentiation.

[129]  J. Wise,et al.  Metallothionein gene duplications and metal tolerance in natural populations of Drosophila melanogaster. , 1987, Genetics.

[130]  M Raymond,et al.  Amplification of an esterase gene is responsible for insecticide resistance in a California Culex mosquito , 1986, Science.

[131]  G. Maroni,et al.  Structure and expression of a tandem duplication of the Drosophila metallothionein gene. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[132]  Vel'kov Vv Gene amplification in prokaryote and eukaryote systems , 1982 .

[133]  A. L. Koch Evolution of antibiotic resistance gene function , 1981, Microbiological reviews.

[134]  J. M. Smith Evolution of sex , 1975, Nature.

[135]  Dr. Susumu Ohno Evolution by Gene Duplication , 1970, Springer Berlin Heidelberg.

[136]  J. Sprague,et al.  THIOUREA AS A KEY REAGENT FOR THE PREPARATION OF ALIPHATIC SULPHONYL CHLORIDES AND BROMIDES. , 1936, Science.

[137]  J. Haldane,et al.  The Part Played by Recurrent Mutation in Evolution , 1933, The American Naturalist.

[138]  Naomichi Matsumoto,et al.  Identification of a 3.0-kb major recombination hotspot in patients with Sotos syndrome who carry a common 1.9-Mb microdeletion. , 2005, American journal of human genetics.

[139]  David Haussler,et al.  Covariation in frequencies of substitution, deletion, transposition, and recombination during eutherian evolution. , 2003, Genome research.

[140]  S. Otto,et al.  The evolution of gene duplicates. , 2002, Advances in genetics.

[141]  Ash A. Alizadeh,et al.  Genome-wide analysis of DNA copy-number changes using cDNA microarrays , 1999 .

[142]  F. Urnov,et al.  DNA amplification in DNA puff II/9A of Sciara coprophila. , 1993, Cold Spring Harbor symposia on quantitative biology.

[143]  T. Ohta,et al.  Role of gene duplication in evolution. , 1989, Genome.

[144]  Edward Pollak,et al.  The Neutral Theory of Molecular Evolution. , 2022 .