Intracranial hemorrhage management in the multi-omics era.

[1]  Yanhong Zhou,et al.  Multi-omics reveals specific host metabolism-microbiome associations in intracerebral hemorrhage , 2022, Frontiers in Cellular and Infection Microbiology.

[2]  Jie Yang,et al.  Gut microbiota composition reflects disease progression, severity and outcome, and dysfunctional immune responses in patients with hypertensive intracerebral hemorrhage , 2022, Frontiers in Immunology.

[3]  Haixia Du,et al.  Multi-omics research strategies in ischemic stroke: A multidimensional perspective , 2022, Ageing Research Reviews.

[4]  Hao Hu,et al.  Allosteric activation of the metabolic enzyme GPD1 inhibits bladder cancer growth via the lysoPC-PAFR-TRPV2 axis , 2022, Journal of Hematology & Oncology.

[5]  K. Hochrainer,et al.  Stroke Proteomics: From Discovery to Diagnostic and Therapeutic Applications. , 2022, Circulation research.

[6]  Shumei Wang,et al.  Integrated 16S rRNA gene sequencing and LC/MS-based metabolomics ascertained synergistic influences of combination acupuncture and NaoMaiTong on ischemic stroke. , 2022, Journal of ethnopharmacology.

[7]  Yi Zeng,et al.  Genome-Wide DNA Methylation Pattern in Whole Blood Associated With Primary Intracerebral Hemorrhage , 2021, Frontiers in Immunology.

[8]  Marie-Pier Scott-Boyer,et al.  Integration strategies of multi-omics data for machine learning analysis , 2021, Computational and structural biotechnology journal.

[9]  B. Kissela,et al.  Rare Missense Functional Variants at COL4A1 and COL4A2 in Sporadic Intracerebral Hemorrhage , 2021, Neurology.

[10]  Xiangwei Gao,et al.  RNA modifications in cardiovascular diseases, the potential therapeutic targets. , 2021, Life sciences.

[11]  E. Trucco,et al.  Using machine learning approaches for multi-omics data analysis: A review. , 2021, Biotechnology advances.

[12]  H. Shang,et al.  iTRAQ-Based Quantitative Proteomics Indicated Nrf2/OPTN-Mediated Mitophagy Inhibits NLRP3 Inflammasome Activation after Intracerebral Hemorrhage , 2021, Oxidative medicine and cellular longevity.

[13]  J. Ping,et al.  Identification of circular RNA expression profiles and potential biomarkers for intracerebral hemorrhage. , 2021, Epigenomics.

[14]  M. Westphal,et al.  Intrathecal and systemic alterations of L-arginine metabolism in patients after intracerebral hemorrhage , 2021, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[15]  Chun-Yang Zhang,et al.  Metabolomic profiling of fatty acid biomarkers for intracerebral hemorrhage stroke. , 2021, Talanta.

[16]  H. Shang,et al.  Proteomic Analysis of Perihematoma Tissue from Patients with Intracerebral Hemorrhage Using iTRAQ-Based Quantitative Proteomics , 2021, Neuromolecular medicine.

[17]  Yinglin Cui,et al.  Proteomics and metabolomics of raw rhubarb and wine-processed rhubarb in the treatment of rats with intracerebral hemorrhage , 2020, Annals of translational medicine.

[18]  Jefte M. Drijvers,et al.  Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity , 2020, Cell.

[19]  Xiang Wang,et al.  High plasma levels of trimethylamine N-oxide are associated with poor outcome in intracerebral hemorrhage patients , 2020, Neurological Sciences.

[20]  Stijn Sonneveld,et al.  Heterogeneity in mRNA Translation. , 2020, Trends in cell biology.

[21]  Sangeetha Sukumari-Ramesh,et al.  A Combined Proteomics and Bioinformatics Approach Reveals Novel Signaling Pathways and Molecular Targets After Intracerebral Hemorrhage , 2020, Journal of Molecular Neuroscience.

[22]  Li Jin,et al.  The progress of gut microbiome research related to brain disorders , 2020, Journal of Neuroinflammation.

[23]  S. Jee,et al.  Global metabolomics analysis of serum from humans at risk of thrombotic stroke. , 2020, The Analyst.

[24]  M. Volpe,et al.  Pathogenesis of Ischemic Stroke: Role of Epigenetic Mechanisms , 2020, Genes.

[25]  C. Reis,et al.  Circular RNA expression profiles alter significantly after intracerebral hemorrhage in rats , 2020, Brain Research.

[26]  F. Sharp,et al.  MicroRNA and their target mRNAs change expression in whole blood of patients after intracerebral hemorrhage , 2020, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[27]  W. Kimberly,et al.  High-throughput metabolite profiling: identification of plasma taurine as a potential biomarker of functional outcome after aneurysmal subarachnoid hemorrhage. , 2019, Journal of neurosurgery.

[28]  Sangeetha Sukumari-Ramesh,et al.  Intracerebral Hemorrhage: Blood Components and Neurotoxicity , 2019, Brain sciences.

[29]  M. Lawton,et al.  Global brain inflammation in stroke , 2019, The Lancet Neurology.

[30]  K. Chu,et al.  Altered long noncoding RNA profile after intracerebral hemorrhage , 2019, Annals of clinical and translational neurology.

[31]  Xiaodong Li,et al.  MicroRNA-126-3p Attenuates Intracerebral Hemorrhage-Induced Blood-Brain Barrier Disruption by Regulating VCAM-1 Expression , 2019, Front. Neurosci..

[32]  S. Mayer,et al.  Perihematomal Edema After Spontaneous Intracerebral Hemorrhage. , 2019, Stroke.

[33]  Jun Chen,et al.  Systemic inflammation in hemorrhagic strokes – A novel neurological sign and therapeutic target? , 2019, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[34]  Yang Wang,et al.  iTRAQ-based quantitative proteomics reveals the neuroprotection of rhubarb in experimental intracerebral hemorrhage. , 2019, Journal of ethnopharmacology.

[35]  Núria Malats,et al.  Challenges in the Integration of Omics and Non-Omics Data , 2019, Genes.

[36]  N. Marklund,et al.  Dynamic protein changes in the perihaemorrhagic zone of Surgically Treated Intracerebral Haemorrhage Patients , 2019, Scientific Reports.

[37]  G. Theodoridis,et al.  Targeted urine metabolomics in preterm neonates with intraventricular hemorrhage. , 2019, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[38]  Daming Zhang,et al.  Circulating MicroRNAs as a Potential Non-invasive Biomarkers of Spontaneous Intracerebral Hemorrhage. , 2019, World neurosurgery.

[39]  Yi-Ju Li,et al.  Sex Differences in Gene and Protein Expression After Intracerebral Hemorrhage in Mice , 2019, Translational Stroke Research.

[40]  Shuixiang Deng,et al.  Biomarker and Drug Target Discovery Using Quantitative Proteomics Post-Intracerebral Hemorrhage Stroke in the Rat Brain , 2018, Journal of Molecular Neuroscience.

[41]  L. Tang,et al.  miR-27a-3p protects against blood–brain barrier disruption and brain injury after intracerebral hemorrhage by targeting endothelial aquaporin-11 , 2018, The Journal of Biological Chemistry.

[42]  Yang Wang,et al.  Quantitative proteomic analysis of intracerebral hemorrhage in rats with a focus on brain energy metabolism , 2018, Brain and behavior.

[43]  Bin Zhou,et al.  LncRNA‐FENDRR mediates VEGFA to promote the apoptosis of brain microvascular endothelial cells via regulating miR‐126 in mice with hypertensive intracerebral hemorrhage , 2018, Microcirculation.

[44]  Craig S Anderson,et al.  Intracerebral haemorrhage: current approaches to acute management. , 2018, Lancet.

[45]  zhao yang,et al.  Let-7a promotes microglia M2 polarization by targeting CKIP-1 following ICH. , 2018, Immunology letters.

[46]  X-D Zhang,et al.  MiR-7 alleviates secondary inflammatory response of microglia caused by cerebral hemorrhage through inhibiting TLR4 expression. , 2018, European review for medical and pharmacological sciences.

[47]  Q. Guo,et al.  MiR-590-5p alleviates intracerebral hemorrhage-induced brain injury through targeting Peli1 gene expression. , 2018, Biochemical and biophysical research communications.

[48]  Andrew D. Johnson,et al.  Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes , 2018, Nature Genetics.

[49]  B. Thompson,et al.  Injury mechanisms in acute intracerebral hemorrhage , 2017, Neuropharmacology.

[50]  Ping Wang,et al.  MicroRNA-21 and microRNA-146a negatively regulate the secondary inflammatory response of microglia after intracerebral hemorrhage. , 2018, International journal of clinical and experimental pathology.

[51]  A. Au,et al.  Metabolomics and Lipidomics of Ischemic Stroke. , 2018, Advances in clinical chemistry.

[52]  P. Gao,et al.  Distinguishing Intracerebral Hemorrhage from Acute Cerebral Infarction through Metabolomics. , 2017, Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion.

[53]  J. Hao,et al.  MicroRNA-132 attenuates neurobehavioral and neuropathological changes associated with intracerebral hemorrhage in mice , 2017, Neurochemistry International.

[54]  Boomin Choi,et al.  Heme molecule functions as an endogenous agonist of astrocyte TLR2 to contribute to secondary brain damage after intracerebral hemorrhage , 2017, Molecular Brain.

[55]  Lina Zhang,et al.  Identification of novel biomarker and therapeutic target candidates for acute intracerebral hemorrhage by quantitative plasma proteomics , 2017, Clinical Proteomics.

[56]  A. Meretoja,et al.  Natural History of Perihematomal Edema and Impact on Outcome After Intracerebral Hemorrhage , 2017, Stroke.

[57]  Guang Yang,et al.  MiR-124 contributes to M2 polarization of microglia and confers brain inflammatory protection via the C/EBP-α pathway in intracerebral hemorrhage. , 2017, Immunology letters.

[58]  John H. Zhang,et al.  Early Hematoma Enlargement in Primary Intracerebral Hemorrhage. , 2017, Current drug targets.

[59]  D. Woo,et al.  Genetics of Spontaneous Intracerebral Hemorrhage. , 2017, Stroke.

[60]  R. Keep,et al.  Early Erythrolysis in the Hematoma After Experimental Intracerebral Hemorrhage , 2016, Translational Stroke Research.

[61]  Núria Malats,et al.  Toward the integration of Omics data in epidemiological studies: still a “long and winding road” , 2016, Genetic epidemiology.

[62]  L. Tang,et al.  Differential expression of circulating microRNAs in blood and haematoma samples from patients with intracerebral haemorrhage , 2016, The Journal of international medical research.

[63]  Q. Dong,et al.  Effects of intracerebral hemorrhage on 5-hydroxymethylcytosine modification in mouse brains , 2016, Neuropsychiatric disease and treatment.

[64]  John H. Zhang,et al.  PPARγ-induced upregulation of CD36 enhances hematoma resolution and attenuates long-term neurological deficits after germinal matrix hemorrhage in neonatal rats , 2016, Neurobiology of Disease.

[65]  Zhen Zhao,et al.  Establishment and Dysfunction of the Blood-Brain Barrier , 2015, Cell.

[66]  Bangqing Yuan,et al.  MicroRNA-223 regulates inflammation and brain injury via feedback to NLRP3 inflammasome after intracerebral hemorrhage. , 2015, Molecular immunology.

[67]  Rui Li,et al.  Whole transcriptome analysis with sequencing: methods, challenges and potential solutions , 2015, Cellular and Molecular Life Sciences.

[68]  M. Frosch,et al.  Cerebral amyloid angiopathy with and without hemorrhage , 2015, Neurology.

[69]  M. Lai,et al.  5-Hydroxymethylcytosine and disease. , 2014, Mutation research. Reviews in mutation research.

[70]  R. Keep,et al.  Vascular disruption and blood–brain barrier dysfunction in intracerebral hemorrhage , 2014, Fluids and Barriers of the CNS.

[71]  Lisa J. Martin,et al.  Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage. , 2014, American journal of human genetics.

[72]  Qing-Wu Yang,et al.  Inflammation in intracerebral hemorrhage: From mechanisms to clinical translation , 2014, Progress in Neurobiology.

[73]  Zhiping Hu,et al.  Progressing haemorrhagic stroke: categories, causes, mechanisms and managements , 2014, Journal of Neurology.

[74]  Qing-Wu Yang,et al.  Iron and Intracerebral Hemorrhage: From Mechanism to Translation , 2014, Translational Stroke Research.

[75]  Sylvia Baedorf Kassis,et al.  Heritability Estimates Identify a Substantial Genetic Contribution to Risk and Outcome of Intracerebral Hemorrhage , 2013, Stroke.

[76]  Xiqiang Liu,et al.  Evaluating the microRNA targeting sites by luciferase reporter gene assay. , 2013, Methods in molecular biology.

[77]  A. Baccarelli,et al.  Next steps in cardiovascular disease genomic research--sequencing, epigenetics, and transcriptomics. , 2012, Clinical chemistry.

[78]  Ale Algra,et al.  Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis , 2010, The Lancet Neurology.

[79]  A. Padovani,et al.  Cerebral amyloid angiopathy-related hemorrhages , 2008, Neurological Sciences.

[80]  M. Woodward,et al.  APOE genotype, ethnicity, and the risk of cerebral hemorrhage , 2008, Neurology.

[81]  Ji-Kang Park,et al.  Intracerebral hemorrhages in CADASIL , 2006, Neurology.

[82]  J. Szaflarski,et al.  Genetic and Environmental Risk Factors for Intracerebral Hemorrhage: Preliminary Results of a Population-Based Study , 2002, Stroke.

[83]  Y. Fujii,et al.  Hematoma enlargement in spontaneous intracerebral hemorrhage. , 1994, Journal of neurosurgery.