Challenges and directions in studying cell–cell communication by extracellular vesicles

[1]  K. Rilla.  Diverse plasma membrane protrusions act as platforms for extracellular vesicle shedding , 2021, Journal of extracellular vesicles.

[2]  Á. Kittel,et al.  Formation of a protein corona on the surface of extracellular vesicles in blood plasma , 2021, Journal of extracellular vesicles.

[3]  Eva-Maria Krämer-Albers,et al.  The power of imaging to understand extracellular vesicle biology in vivo , 2021, Nature Methods.

[4]  F. Perez,et al.  Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 , 2021, Nature Communications.

[5]  R. Schekman,et al.  Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates , 2021, bioRxiv.

[6]  R. Moniz,et al.  ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance , 2021, Communications biology.

[7]  K. Pienta,et al.  Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single‐particle analysis platforms , 2021, Journal of extracellular vesicles.

[8]  James W. Clancy,et al.  The ins and outs of microvesicles , 2021, FASEB bioAdvances.

[9]  J. Debnath,et al.  Emerging roles for the autophagy machinery in extracellular vesicle biogenesis and secretion , 2021, FASEB bioAdvances.

[10]  G. Raposo,et al.  Centrosome amplification mediates small extracellular vesicle secretion via lysosome disruption , 2021, Current Biology.

[11]  N. Paul,et al.  Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes , 2021, eLife.

[12]  G. Raposo,et al.  Microvilli-derived Extracellular Vesicles Govern Morphogenesis in Drosophila wing epithelium , 2020, bioRxiv.

[13]  S. Hunt,et al.  Extracellular vesicles and the extracellular matrix: a new paradigm or old news? , 2020, Biochemical Society transactions.

[14]  S. Priori,et al.  A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart , 2020, Cell.

[15]  Rienk Nieuwland,et al.  Methods for Separation and Characterization of Extracellular Vesicles: Results of a Worldwide Survey Performed by the ISEV Rigor and Standardization Subcommittee , 2020, Cells.

[16]  G. van Niel,et al.  Transmissible Endosomal Intoxication: A Balance between Exosomes and Lysosomes at the Basis of Intercellular Amyloid Propagation , 2020, Biomedicines.

[17]  L. Laurent,et al.  RNA delivery by extracellular vesicles in mammalian cells and its applications , 2020, Nature Reviews Molecular Cell Biology.

[18]  M. Costafreda,et al.  Exosome mimicry by an HAVCR1/NPC1 pathway of endosomal fusion mediates hepatitis A virus infection , 2020, Nature Microbiology.

[19]  Alissa M. Weaver,et al.  A live cell reporter of exosome secretion and uptake reveals pathfinding behavior of migrating cells , 2020, Nature Communications.

[20]  B. Giepmans,et al.  Endocytosis of Extracellular Vesicles and Release of Their Cargo from Endosomes , 2020, ACS nano.

[21]  Y. Karamanos,et al.  Targeting and Crossing the Blood-Brain Barrier with Extracellular Vesicles , 2020, Cells.

[22]  Heedoo Lee,et al.  Sorting Mechanisms for MicroRNAs into Extracellular Vesicles and Their Associated Diseases , 2020, Cells.

[23]  Daniel G. Anderson,et al.  Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backbone , 2020, Nature Biomedical Engineering.

[24]  Jian Shen,et al.  Exosomes derived from HeLa cells break down vascular integrity by triggering endoplasmic reticulum stress in endothelial cells , 2020, Journal of extracellular vesicles.

[25]  Hector H. Huang,et al.  The LC3-Conjugation Machinery Specifies the Loading of RNA-Binding Proteins into Extracellular Vesicles , 2019, Nature Cell Biology.

[26]  Taro Shimizu,et al.  Cancer cell-type tropism is one of crucial determinants for the efficient systemic delivery of cancer cell-derived exosomes to tumor tissues. , 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[27]  S. Bhattacharyya,et al.  Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop , 2019, Journal of extracellular vesicles.

[28]  Mats Nilsson,et al.  Profiling surface proteins on individual exosomes using a proximity barcoding assay , 2019, Nature Communications.

[29]  C. Théry,et al.  Extracellular vesicles or exosomes? On primacy, precision, and popularity influencing a choice of nomenclature , 2019, Journal of extracellular vesicles.

[30]  Grégory Lavieu,et al.  Content release of extracellular vesicles in a cell‐free extract , 2019, FEBS letters.

[31]  G. Raposo,et al.  Lysosome-related organelles as functional adaptations of the endolysosomal system. , 2019, Current opinion in cell biology.

[32]  A. Hutcheon,et al.  Extracellular Vesicles and Cell–Cell Communication in the Cornea , 2019, Anatomical record.

[33]  J. Lötvall,et al.  Advances in therapeutic applications of extracellular vesicles , 2019, Science Translational Medicine.

[34]  Dylan T Burnette,et al.  Reassessment of Exosome Composition , 2019, Cell.

[35]  Eliot T. McKinley,et al.  Transfer of Functional Cargo in Exomeres , 2019, Cell reports.

[36]  Joshua A Welsh,et al.  Optimisation of imaging flow cytometry for the analysis of single extracellular vesicles by using fluorescence-tagged vesicles as biological reference material , 2019, Journal of extracellular vesicles.

[37]  F. Del Bene,et al.  Live Tracking of Inter-organ Communication by Endogenous Exosomes In Vivo. , 2019, Developmental cell.

[38]  F. Delalande,et al.  Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo. , 2019, Developmental cell.

[39]  C. Théry,et al.  Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication , 2019, Nature Cell Biology.

[40]  C. Lai,et al.  Imaging extracellular vesicles: current and emerging methods , 2018, Journal of Biomedical Science.

[41]  Jing Xu,et al.  Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines , 2018, Journal of Extracellular Vesicles.

[42]  Zhenghong Yuan,et al.  Exosomes Exploit the Virus Entry Machinery and Pathway To Transmit Alpha Interferon-Induced Antiviral Activity , 2018, Journal of Virology.

[43]  H. Valadi,et al.  Extracellular Vesicles and Matrix Remodeling Enzymes: The Emerging Roles in Extracellular Matrix Remodeling, Progression of Diseases and Tissue Repair , 2018, Cells.

[44]  Christopher G. Adda,et al.  Arrestin‐Domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles , 2018, Proteomics.

[45]  G. van Niel,et al.  To be or not to be... secreted as exosomes, a balance finely tuned by the mechanisms of biogenesis. , 2018, Essays in biochemistry.

[46]  A. Maitra,et al.  Generation and testing of clinical-grade exosomes for pancreatic cancer. , 2018, JCI insight.

[47]  E. Buzás,et al.  Molecular interactions at the surface of extracellular vesicles , 2018, Seminars in Immunopathology.

[48]  T. Lagerweij,et al.  Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8 , 2018, Journal of extracellular vesicles.

[49]  André M. N. Silva,et al.  Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation , 2018, Nature Cell Biology.

[50]  A. Elkahloun,et al.  A function-blocking CD47 antibody modulates extracellular vesicle-mediated intercellular signaling between breast carcinoma cells and endothelial cells , 2018, Journal of Cell Communication and Signaling.

[51]  Emmanuel Dias-Neto,et al.  Technical challenges of working with extracellular vesicles. , 2018, Nanoscale.

[52]  Graça Raposo,et al.  Shedding light on the cell biology of extracellular vesicles , 2018, Nature Reviews Molecular Cell Biology.

[53]  J. Neefjes,et al.  Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling , 2018, The Journal of cell biology.

[54]  J. Briggs,et al.  The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer , 2018, Cell.

[55]  L. Fradkin,et al.  Retrovirus-like Gag Protein Arc1 Binds RNA and Traffics across Synaptic Boutons , 2018, Cell.

[56]  Zhibin Li,et al.  Protein Profiling and Sizing of Extracellular Vesicles from Colorectal Cancer Patients via Flow Cytometry. , 2018, ACS nano.

[57]  C. Théry,et al.  Why the need and how to approach the functional diversity of extracellular vesicles , 2017, Philosophical Transactions of the Royal Society B: Biological Sciences.

[58]  P. Nieminen,et al.  Extracellular vesicles are integral and functional components of the extracellular matrix. , 2017, Matrix biology : journal of the International Society for Matrix Biology.

[59]  D. Margolis,et al.  Neutrophil microparticle production and inflammasome activation by hyperglycemia due to cytoskeletal instability , 2017, The Journal of Biological Chemistry.

[60]  Yuki Takahashi,et al.  Pharmacokinetics of Exosomes-An Important Factor for Elucidating the Biological Roles of Exosomes and for the Development of Exosome-Based Therapeutics. , 2017, Journal of pharmaceutical sciences.

[61]  Romaric Lacroix,et al.  Methodological Guidelines to Study Extracellular Vesicles. , 2017, Circulation research.

[62]  Raghu Kalluri,et al.  Exosomes Facilitate Therapeutic Targeting of Oncogenic Kras in Pancreatic Cancer , 2017, Nature.

[63]  Patrizia Agostinis,et al.  EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research , 2017, Nature Methods.

[64]  D. Hall,et al.  C. elegans Neurons Jettison Protein Aggregates and Mitochondria Under Neurotoxic Stress , 2017, Nature.

[65]  Paolo Bettotti,et al.  Digital Detection of Exosomes by Interferometric Imaging , 2016, Scientific Reports.

[66]  G. Banting,et al.  Tetherin is an exosomal tether , 2016, eLife.

[67]  T. Ochiya,et al.  Generation of a novel transgenic rat model for tracing extracellular vesicles in body fluids , 2016, Scientific Reports.

[68]  James W. Clancy,et al.  Biology and biogenesis of shed microvesicles , 2016, Small GTPases.

[69]  A. Llorente,et al.  PIKfyve inhibition increases exosome release and induces secretory autophagy , 2016, Cellular and Molecular Life Sciences.

[70]  Melissa M. Sprachman,et al.  SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions , 2016, Science.

[71]  Gary K. Schwartz,et al.  Tumour exosome integrins determine organotropic metastasis , 2015, Nature.

[72]  James W. Clancy,et al.  Extracellular microvesicles and invadopodia mediate non-overlapping modes of tumor cell invasion , 2015, Scientific Reports.

[73]  Jacco van Rheenen,et al.  In Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior , 2015, Cell.

[74]  F. Sánchez‐Madrid,et al.  Organizing Polarized Delivery of Exosomes at Synapses , 2015, Traffic.

[75]  P. Altevogt,et al.  Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment , 2015, Oncoimmunology.

[76]  J. Debnath,et al.  ATG12-ATG3 Interacts with Alix to Promote Basal Autophagic Flux and Late Endosome Function , 2015, Nature Cell Biology.

[77]  L. O’Driscoll,et al.  Biological properties of extracellular vesicles and their physiological functions , 2015, Journal of extracellular vesicles.

[78]  Y. Li,et al.  Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration , 2014, Cell Research.

[79]  David L. Stokes,et al.  Polarized release of TCR-enriched microvesicles at the T cell immunological synapse , 2014, Nature.

[80]  R. Pink,et al.  Routes and mechanisms of extracellular vesicle uptake , 2014, Journal of extracellular vesicles.

[81]  Clotilde Théry,et al.  Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles , 2013, Journal of Cell Science.

[82]  M. Zöller,et al.  Host matrix modulation by tumor exosomes promotes motility and invasiveness. , 2013, Neoplasia.

[83]  Ylva Ivarsson,et al.  Syndecan–syntenin–ALIX regulates the biogenesis of exosomes , 2012, Nature Cell Biology.

[84]  Guimei Zhang,et al.  Delivery of chemotherapeutic drugs in tumour cell-derived microparticles , 2012, Nature Communications.

[85]  J. Nance,et al.  The P4-ATPase TAT-5 Inhibits the Budding of Extracellular Vesicles in C. elegans Embryos , 2011, Current Biology.

[86]  P. Saftig,et al.  The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis. , 2011, Developmental cell.

[87]  Fátima Sánchez-Cabo,et al.  Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells , 2011, Nature communications.

[88]  Haitao Wang,et al.  Visualizing of the cellular uptake and intracellular trafficking of exosomes by live‐cell microscopy , 2010, Journal of cellular biochemistry.

[89]  Graca Raposo,et al.  ARF6-Regulated Shedding of Tumor Cell-Derived Plasma Membrane Microvesicles , 2009, Current Biology.

[90]  C. Melief,et al.  MHC II in Dendritic Cells is Targeted to Lysosomes or T Cell‐Induced Exosomes Via Distinct Multivesicular Body Pathways , 2009, Traffic.

[91]  Petra Schwille,et al.  Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes , 2008, Science.

[92]  Simon C Watkins,et al.  Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells. , 2004, Blood.

[93]  M. Vidal,et al.  Exosome Release Is Regulated by a Calcium-dependent Mechanism in K562 Cells* , 2003, Journal of Biological Chemistry.

[94]  J. Slot,et al.  Immunoelectron Microscopic Localization of Cholesterol Using Biotinylated and Non-cytolytic Perfringolysin O , 2002, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[95]  M. Kleijmeer,et al.  Follicular Dendritic Cells Carry MHC Class II-Expressing Microvesicles at Their Surface1 , 2000, The Journal of Immunology.

[96]  A. Khvorova,et al.  RNAs that bind and change the permeability of phospholipid membranes. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[97]  K. Jacobson,et al.  The dynamic structure of the pericellular matrix on living cells , 1993, The Journal of cell biology.

[98]  I. Poon,et al.  Apoptotic Bodies: Mechanism of Formation, Isolation and Functional Relevance. , 2021, Sub-cellular biochemistry.

[99]  Miguel C. Seabra,et al.  Rab27a and Rab27b control different steps of the exosome secretion pathway , 2010, Nature Cell Biology.

[100]  Miguel C. Seabra,et al.  1 Rab 27 a and Rab 27 b control different steps of the exosome secretion pathway , 2009 .