Susceptibility to JRA/JIA: complementing general autoimmune and arthritis traits

[1]  J. Tuomilehto,et al.  Finnish case–control and family studies support PTPN22 R620W polymorphism as a risk factor in rheumatoid arthritis, but suggest only minimal or no effect in juvenile idiopathic arthritis , 2005, Genes and Immunity.

[2]  Elizabeth W Karlson,et al.  Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4. , 2005, American journal of human genetics.

[3]  Steven J. Schrodi,et al.  PTPN22 genetic variation: evidence for multiple variants associated with rheumatoid arthritis. , 2005, American journal of human genetics.

[4]  B. Franke,et al.  Correlation of rheumatoid arthritis severity with the genetic functional variants and circulating levels of macrophage migration inhibitory factor. , 2005, Arthritis and rheumatism.

[5]  F. Nicoletti,et al.  Critical role of macrophage migration inhibitory factor activity in experimental autoimmune diabetes. , 2005, Endocrinology.

[6]  Wendy Thomson,et al.  Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: further support that PTPN22 is an autoimmunity gene. , 2005, Arthritis and rheumatism.

[7]  H. Shimizu,et al.  Promoter region polymorphism of macrophage migration inhibitory factor is strong risk factor for young onset of extensive alopecia areata , 2005, Genes and Immunity.

[8]  K. Pfeffer,et al.  The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games , 2005, Immunology.

[9]  K. Boberg,et al.  Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases , 2005, Genes and Immunity.

[10]  P. Gregersen.  Pathways to gene identification in rheumatoid arthritis: PTPN22 and beyond , 2005, Immunological reviews.

[11]  S. Gough,et al.  CTLA4 gene polymorphism and autoimmunity , 2005, Immunological reviews.

[12]  Annette Lee,et al.  Analysis of Families in the Multiple Autoimmune Disease Genetics Consortium (madgc) Collection: the Ptpn22 620w Allele Associates with Multiple Autoimmune Phenotypes , 2022 .

[13]  V. Pascual,et al.  Cross-regulation of TNF and IFN-¿ in autoimmune diseases , 2005 .

[14]  J. Tuomilehto,et al.  Association of SLC11A1 (NRAMP1) with persistent oligoarticular and polyarticular rheumatoid factor-negative juvenile idiopathic arthritis in Finnish patients: haplotype analysis in Finnish families. , 2005, Arthritis and rheumatism.

[15]  V. Pascual,et al.  Cross-regulation of TNF and IFN-alpha in autoimmune diseases. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[16]  C. Held,et al.  Genetic predisposition of the interleukin-6 response to inflammation: implications for a variety of major diseases? , 2004, Clinical chemistry.

[17]  Sampath Prahalad,et al.  A genome-wide scan for juvenile rheumatoid arthritis in affected sibpair families provides evidence of linkage. , 2004, Arthritis and rheumatism.

[18]  Y. Matsui,et al.  Blockade of macrophage migration inhibitory factor ameliorates experimental autoimmune myocarditis. , 2004, Journal of molecular and cellular cardiology.

[19]  A. Vicente,et al.  Evidence for CTLA4 as a susceptibility gene for systemic lupus erythematosus , 2004, European Journal of Human Genetics.

[20]  Steven J. Schrodi,et al.  A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. , 2004, American journal of human genetics.

[21]  D. Glass,et al.  Juvenile rheumatoid arthritis affected sibpairs: extent of clinical phenotype concordance. , 2004, Arthritis and rheumatism.

[22]  E. Zeggini,et al.  A functional promoter haplotype of macrophage migration inhibitory factor is linked and associated with juvenile idiopathic arthritis. , 2004, Arthritis and rheumatism.

[23]  S. Giannouli,et al.  Autoimmune manifestations in human myelodysplasia: a positive correlation with interferon regulatory factor-1 (IRF-1) expression , 2004, Annals of the Rheumatic Diseases.

[24]  Nunzio Bottini,et al.  A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes , 2004, Nature Genetics.

[25]  M. Suarez‐Almazor,et al.  International League of Associations for Rheumatology: International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001 , 2004 .

[26]  L. Diehl,et al.  PEST Domain-Enriched Tyrosine Phosphatase (PEP) Regulation of Effector/Memory T Cells , 2004, Science.

[27]  M. Simmonds,et al.  Genetic insights into disease mechanisms of autoimmunity. , 2004, British medical bulletin.

[28]  T. Hibi,et al.  Association of the −173 G/C polymorphism of the macrophage migration inhibitory factor gene with ulcerative colitis , 2004, Journal of Gastroenterology.

[29]  J. Epplen,et al.  Complex genetic predisposition in adult and juvenile rheumatoid arthritis , 2004, BMC Genetics.

[30]  S. Fisher,et al.  The -174G allele of the interleukin-6 gene confers susceptibility to systemic arthritis in children: a multicenter study using simplex and multiplex juvenile idiopathic arthritis families. , 2003, Arthritis and rheumatism.

[31]  S. Chang,et al.  Association of CTLA4 gene A-G polymorphism with rheumatoid arthritis in Chinese , 2003, Clinical Rheumatology.

[32]  Luc J. Smink,et al.  Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease , 2003, Nature.

[33]  P. Gregersen,et al.  Macrophage migration inhibitory factor, MIF alleles, and the genetics of inflammatory disorders: incorporating disease outcome into the definition of phenotype. , 2003, Arthritis and rheumatism.

[34]  W. Thomson,et al.  Functional and prognostic relevance of the -173 polymorphism of the macrophage migration inhibitory factor gene in systemic-onset juvenile idiopathic arthritis. , 2003, Arthritis and rheumatism.

[35]  N. Wilkinson,et al.  Disseminated congenital neuroblastoma presenting at birth , 2003, Archives of disease in childhood.

[36]  Jacqueline K. White,et al.  Divalent cation transport and susceptibility to infectious and autoimmune disease: continuation of the Ity/Lsh/Bcg/Nramp1/Slc11a1 gene story. , 2003, Immunology letters.

[37]  E. Zeggini,et al.  Linkage and association studies of single-nucleotide polymorphism-tagged tumor necrosis factor haplotypes in juvenile oligoarthritis. , 2002, Arthritis and rheumatism.

[38]  D. Alarcón-Segovia,et al.  A major susceptibility locus for systemic lupus erythemathosus maps to chromosome 1q31. , 2002, American journal of human genetics.

[39]  P. Rieckmann,et al.  CTLA4 exon 1 dimorphism is associated with primary progressive multiple sclerosis , 2002, Journal of Neuroimmunology.

[40]  E. Zeggini,et al.  Mutation screening of the macrophage migration inhibitory factor gene: positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile idiopathic arthritis. , 2002, Arthritis and rheumatism.

[41]  Sampath Prahalad,et al.  Increased prevalence of familial autoimmunity in simplex and multiplex families with juvenile rheumatoid arthritis. , 2002, Arthritis and rheumatism.

[42]  D. Lovell,et al.  Advanced therapy for juvenile arthritis. , 2002, Best practice & research. Clinical rheumatology.

[43]  C. Sanjeevi,et al.  Major histocompatibility complex class I chain related (MIC) A gene, TNFa microsatellite alleles and TNFB alleles in juvenile idiopathic arthritis patients from Latvia. , 2002, Human immunology.

[44]  P. Gregersen,et al.  A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis , 2002, Genes and Immunity.

[45]  Ali Duzova,et al.  Tumour necrosis factor α G→A −238 and G→A −308 polymorphisms in juvenile idiopathic arthritis , 2002 .

[46]  S. Pearce,et al.  An association between the CTLA4 exon 1 polymorphism and early rheumatoid arthritis with autoimmune endocrinopathies. , 2002, Rheumatology.

[47]  J. Terwilliger,et al.  Genomewide linkage analysis of celiac disease in Finnish families. , 2002, American journal of human genetics.

[48]  J. Franklyn,et al.  Polymorphism of the CTLA-4 gene is associated with autoimmune hypothyroidism in the United Kingdom. , 2002, Thyroid : official journal of the American Thyroid Association.

[49]  A. Bakkaloğlu,et al.  Tumour necrosis factor alpha G-->A -238 and G-->A -308 polymorphisms in juvenile idiopathic arthritis. , 2002, Rheumatology.

[50]  S. Sawcer,et al.  A genome screen for multiple sclerosis in Sardinian multiplex families , 2001, European Journal of Human Genetics.

[51]  J. Barrett,et al.  Cytokine gene polymorphisms and susceptibility to juvenile idiopathic arthritis , 2001 .

[52]  G. Assmann,et al.  Interleukin-6 promoter polymorphism (--174 G/C) in Caucasian German patients with systemic lupus erythematosus. , 2001, Rheumatology.

[53]  J. Barrett,et al.  Cytokine gene polymorphisms and susceptibility to juvenile idiopathic arthritis. British Paediatric Rheumatology Study Group. , 2001, Arthritis and rheumatism.

[54]  A. Demaine,et al.  A polymorphism in the promoter region of the gene for interleukin-6 is associated with susceptibility to type 1 diabetes mellitus. , 2000, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

[55]  S D Thompson,et al.  Juvenile rheumatoid arthritis: linkage to HLA demonstrated by allele sharing in affected sibpairs. , 2000, Arthritis and rheumatism.

[56]  A. Grom,et al.  T-cell and T-cell receptor abnormalities in the immunopathogenesis of juvenile rheumatoid arthritis , 2000, Current opinion in rheumatology.

[57]  K. Tokunaga,et al.  Independent contribution of HLA-DRB1 and TNFα promoter polymorphisms to the susceptibility to Crohn’s disease , 2000, Genes and Immunity.

[58]  E. N. Miller,et al.  Polymorphism at NRAMP1 and D2S1471 loci associated with juvenile rheumatoid arthritis. , 2000, Arthritis and rheumatism.

[59]  W. Thomson,et al.  Different gene loci within the HLA-DR and TNF regions are independently associated with susceptibility and severity in Spanish rheumatoid arthritis patients. , 2000, Tissue antigens.

[60]  S. Pearce,et al.  CTLA-4 gene polymorphism confers susceptibility to primary biliary cirrhosis. , 2000, Journal of hepatology.

[61]  T. Olsson,et al.  Lack of association between the interferon regulatory factor-1 (IRF1) locus at 5q31.1 and multiple sclerosis in Germany, Northern Italy, Sardinia and Sweden , 2000, Genes and Immunity.

[62]  T. Sasazuki,et al.  Identification of a genetic risk factor for systemic juvenile rheumatoid arthritis in the 5'-flanking region of the TNFalpha gene and HLA genes. , 1999, Arthritis and rheumatism.

[63]  D. Glass,et al.  Juvenile rheumatoid arthritis as a complex genetic trait. , 1999, Arthritis and rheumatism.

[64]  D. Glass,et al.  Age-specific effects of juvenile rheumatoid arthritis-associated HLA alleles. , 1999, Arthritis and rheumatism.

[65]  A. Silman,et al.  Combined sib-TDT and TDT provide evidence for linkage of the interleukin-1 gene cluster to erosive rheumatoid arthritis. , 1999, Human molecular genetics.

[66]  J. Morrison,et al.  Genome-wide screen for systemic lupus erythematosus susceptibility genes in multiplex families. , 1999, Human molecular genetics.

[67]  J. Blackwell,et al.  Evidence for a functional repeat polymorphism in the promoter of the human NRAMP1 gene that correlates with autoimmune versus infectious disease susceptibility , 1999, Journal of medical genetics.

[68]  J. Cloutier,et al.  Cooperative Inhibition of  T-Cell Antigen Receptor Signaling by a Complex between a Kinase and a Phosphatase , 1999, The Journal of experimental medicine.

[69]  FarhanA.J BarrettJ.H ThomsonW WorthingtonJ Ollier Wer. DonnR.P.  Absence of association between interleukin 1 alpha and oligoarticular juvenile chronic arthritis in UK patients , 1999 .

[70]  P. Gaffney,et al.  A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[71]  M. Petri,et al.  Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigrees. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[72]  N. Kamatani,et al.  Identification of the gene loci that predispose to rheumatoid arthritis. , 1998, International immunology.

[73]  Watson,et al.  A cytotoxic T lymphocyte antigen‐4 (CTLA‐4) gene polymorphism is associated with autoimmune Addison's disease in English patients , 1998, Clinical endocrinology.

[74]  J. Todd,et al.  Genetic analysis of chromosome 2 in type 1 diabetes: analysis of putative loci IDDM7, IDDM12, and IDDM13 and candidate genes NRAMP1 and IA-2 and the interleukin-1 gene cluster. IMDIAB Group. , 1998, Diabetes.

[75]  M. Suarez‐Almazor,et al.  Revision of the proposed classification criteria for juvenile idiopathic arthritis: Durban, 1997. , 1998, The Journal of rheumatology.

[76]  J S Yudkin,et al.  The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. , 1998, The Journal of clinical investigation.

[77]  Barnett,et al.  No evidence for allelic association of a human CTLA‐4 promoter polymorphism with autoimmune thyroid disease in either population‐based case–control or family‐based studies , 1998, Clinical endocrinology.

[78]  G. Gyapay,et al.  New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[79]  J. Trent,et al.  Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[80]  J. Bach,et al.  CTLA-4 gene polymorphism is associated with predisposition to coeliac disease , 1998, Gut.

[81]  J. Weber,et al.  Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[82]  J. Cloutier,et al.  Sequence Requirements for Association of Protein-tyrosine Phosphatase PEP with the Src Homology 3 Domain of Inhibitory Tyrosine Protein Kinase p50 csk * , 1998, The Journal of Biological Chemistry.

[83]  K. Usadel,et al.  CTLA-4 promoter variants in patients with Graves' disease and Hashimoto's thyroiditis. , 1998, Tissue antigens.

[84]  K. Usadel,et al.  Codon 17 polymorphism of the cytotoxic T lymphocyte antigen 4 gene in Hashimoto's thyroiditis and Addison's disease. , 1997, The Journal of clinical endocrinology and metabolism.

[85]  D. Mosier,et al.  CD4+ T cells from IRF-1-deficient mice exhibit altered patterns of cytokine expression and cell subset homeostasis. , 1997, Journal of immunology.

[86]  F. Pociot,et al.  No association or linkage to IDDM of an interferon regulatory factor-1 gene polymorphism in a Danish population. The Danish Study Group for Diabetes in Childhood. , 1997, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

[87]  S. Galandiuk,et al.  The natural resistance-associated macrophage protein gene is associated with Crohn's disease. , 1997, Surgery.

[88]  K. Kotsa,et al.  A CTLA‐4 gene polymorphism is associated with both Graves' disease and autoimmune hypothyroidism , 1997, Clinical endocrinology.

[89]  R. Atkins,et al.  The Pathogenic Role of Macrophage Migration Inhibitory Factor in Immunologically Induced Kidney Disease in the Rat , 1997, The Journal of experimental medicine.

[90]  D. Glass,et al.  Patterns of expression of tumor necrosis factor α, tumor necrosis factor β, and their receptors in synovia of patients with juvenile rheumatoid arthritis and juvenile spondylarthropathy , 1996 .

[91]  D. Clayton,et al.  Linkage of rheumatoid arthritis to the candidate gene NRAMP1 on 2q35. , 1996, Journal of medical genetics.

[92]  W. Ollier,et al.  JUVENILE CHRONIC ARTHRITIS – A TIME FOR CHANGE? , 1996, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

[93]  J. Blackwell,et al.  Structure and function of the natural-resistance-associated macrophage protein (Nramp1), a candidate protein for infectious and autoimmune disease susceptibility. , 1996, Molecular medicine today.

[94]  E. Albert,et al.  IMMUNOPRINTING EXCLUDES MANY POTENTIAL SUSCEPTIBILITY GENES AS PREDISPOSING TO EARLY ONSET PAUCIARTICULAR JUVENILE CHRONIC ARTHRITIS EXCEPT HLA CLASS II AND TNF , 1995, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

[95]  C. Fink.  Proposal for the development of classification criteria for idiopathic arthritides of childhood. , 1995, The Journal of rheumatology.

[96]  P. Woo,et al.  Inflammatory cytokine responses in juvenile chronic arthritis. , 1995, British journal of rheumatology.

[97]  R. Płoski,et al.  A genetic association between juvenile rheumatoid arthritis and a novel interleukin-1α polymorphism , 1995 .

[98]  P. Liebmann,et al.  Serum cytokines in juvenile rheumatoid arthritis. Correlation with conventional inflammation parameters and clinical subtypes. , 1995, Arthritis and rheumatism.

[99]  R. Płoski,et al.  A genetic association between juvenile rheumatoid arthritis and a novel interleukin-1 alpha polymorphism. , 1995, Arthritis and rheumatism.

[100]  T. Taniguchi,et al.  Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development , 1993, Cell.

[101]  A. Martini,et al.  Correlation of serum interleukin-6 levels with joint involvement and thrombocytosis in systemic juvenile rheumatoid arthritis. , 1991, Arthritis and rheumatism.

[102]  R. Petty,et al.  Textbook of pediatric rheumatology , 1982 .

[103]  J. Baum,et al.  Current proposed revision of JRA Criteria. JRA Criteria Subcommittee of the Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Section of The Arthritis Foundation. , 1977, Arthritis and rheumatism.