Role of p38 mitogen-activated protein kinase in ozone-induced airway hyperresponsiveness and inflammation.

[1]  Hye-Youn Cho,et al.  Ozone-induced lung inflammation and hyperreactivity are mediated via tumor necrosis factor-alpha receptors. , 2001, American journal of physiology. Lung cellular and molecular physiology.

[2]  J. Kang,et al.  Inhibition of c-Jun NH2-terminal kinase or extracellular signal-regulated kinase improves lung injury , 2004, Respiratory research.

[3]  F. D’Acquisto,et al.  Involvement of NF‐κB in the regulation of cyclooxygenase‐2 protein expression in LPS‐stimulated J774 macrophages , 1997, FEBS letters.

[4]  K. Chung,et al.  Importance of p38 mitogen-activated protein kinase pathway in allergic airway remodelling and bronchial hyperresponsiveness. , 2006, European journal of pharmacology.

[5]  C. Cross,et al.  In vivo ozone exposure induces antioxidant/stress-related responses in murine lung and skin. , 2004, Free radical biology & medicine.

[6]  I. Adcock,et al.  Oxidative stress and redox regulation of lung inflammation in COPD , 2006, European Respiratory Journal.

[7]  H. Ichijo,et al.  The ASK1-MAP kinase cascades in mammalian stress response. , 2004, Journal of biochemistry.

[8]  T. Sandström,et al.  Effect of ozone on bronchial mucosal inflammation in asthmatic and healthy subjects. , 2002, Respiratory medicine.

[9]  P. Paggiaro,et al.  Airway inflammatory response to ozone in subjects with different asthma severity. , 1999, The European respiratory journal.

[10]  K. Chung,et al.  Role of cytokine-induced neutrophil chemoattractant (CINC) in ozone-induced airway inflammation and hyperresponsiveness. , 1997, American journal of respiratory and critical care medicine.

[11]  S. Medicherla,et al.  Antinociceptive action of a p38α MAPK inhibitor, SD-282, in a diabetic neuropathy model , 2004, Pain.

[12]  J. Boehm,et al.  p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases , 2003, Nature Reviews Drug Discovery.

[13]  H. Genant,et al.  A Selective p38α Mitogen-Activated Protein Kinase Inhibitor Reverses Cartilage and Bone Destruction in Mice with Collagen-Induced Arthritis , 2006, Journal of Pharmacology and Experimental Therapeutics.

[14]  T. Horie,et al.  Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates hydrogen peroxide-induced apoptosis in human pulmonary vascular endothelial cells , 2003, Critical care medicine.

[15]  S. Kleeberger,et al.  Differential susceptibility to ozone-induced airways hyperreactivity in inbred strains of mice. , 1995, Experimental lung research.

[16]  H. Takizawa.  Bronchial epithelial cells in allergic reactions. , 2005, Current drug targets. Inflammation and allergy.

[17]  I. Adcock,et al.  Potential role of c-Jun NH2-terminal kinase in allergic airway inflammation and remodelling: effects of SP600125. , 2005, European journal of pharmacology.

[18]  K. Kuwano,et al.  Nitric oxide synthase inhibitors attenuate ozone-induced airway inflammation in guinea pigs. Possible role of interleukin-8. , 2000, American journal of respiratory and critical care medicine.

[19]  J. Dean,et al.  The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation. , 2004, Cellular signalling.

[20]  P. Evelson,et al.  H2O2-induced proliferation of primary alveolar epithelial cells is mediated by MAP kinases. , 2005, Antioxidants & redox signaling.

[21]  Mark E. Eiswerth,et al.  Impacts of ozone on the activities of asthmatics: revisiting the data. , 2005, Journal of environmental management.

[22]  M. Peters-Golden,et al.  Prostaglandin E2 synthesis and suppression of fibroblast proliferation by alveolar epithelial cells is cyclooxygenase-2-dependent. , 2002, American journal of respiratory cell and molecular biology.

[23]  J. Massagué,et al.  Transforming growth factor-beta. , 1992, Cancer surveys.

[24]  L. Klotz,et al.  Activation pattern of mitogen‐activated protein kinases elicited by peroxynitrite: attenuation by selenite supplementation , 1999, FEBS letters.

[25]  Masao Tanaka,et al.  Lipopolysaccharide increases cyclo-oxygenase-2 expression in a colon carcinoma cell line through nuclear factor-κB activation , 2000, Oncogene.

[26]  J. Aubry,et al.  Mitogen-activated protein kinase (p38-, JNK-, ERK-) activation pattern induced by extracellular and intracellular singlet oxygen and UVA. , 1999, European journal of biochemistry.

[27]  S. Rennard,et al.  Transforming Growth Factor-β Receptor Type 1 (TGFβRI) Kinase Activity but Not p38 Activation Is Required for TGFβRI-Induced Myofibroblast Differentiation and Profibrotic Gene Expression , 2006, Molecular Pharmacology.

[28]  H. Genant,et al.  A Selective p 38 Mitogen-Activated Protein Kinase Inhibitor Reverses Cartilage and Bone Destruction in Mice with Collagen-Induced Arthritis , 2006 .

[29]  S. Shore,et al.  Ozone-induced airway hyperresponsiveness is reduced in immature mice. , 2002, Journal of applied physiology.

[30]  B. Fanburg,et al.  Reactive oxygen species in cell signaling. , 2000, American journal of physiology. Lung cellular and molecular physiology.

[31]  D. Gupta.  LUNG INJURY, INFLAMMATION, AND INFLAMMATORY STIMULI IN RATS EXPOSED TO OZONE , 2000, Journal of toxicology and environmental health. Part A.

[32]  M. Cobb,et al.  Pharmacological inhibitors of MAPK pathways. , 2002, Trends in pharmacological sciences.

[33]  D. Laskin,et al.  Enhanced production of interleukin-1, tumor necrosis factor-alpha, and fibronectin by rat lung phagocytes following inhalation of a pulmonary irritant. , 1994, American journal of respiratory cell and molecular biology.

[34]  H. Lander,et al.  Differential Activation of Mitogen-activated Protein Kinases by Nitric Oxide-related Species* , 1996, The Journal of Biological Chemistry.

[35]  J. Banegas,et al.  Short-term effects of air pollution on daily asthma emergency room admissions , 2003, European Respiratory Journal.

[36]  P. O'Byrne,et al.  Airway hyperresponsiveness and changes in cell counts in bronchoalveolar lavage after ozone exposure in dogs. , 1984, The American review of respiratory disease.

[37]  H. Frumkin,et al.  Ambient Air Pollution and Respiratory Emergency Department Visits , 2005, Epidemiology.

[38]  S. Shore,et al.  CXCR2 is essential for maximal neutrophil recruitment and methacholine responsiveness after ozone exposure. , 2005, American journal of physiology. Lung cellular and molecular physiology.

[39]  S. Shore,et al.  Role of interleukin-6 in murine airway responses to ozone. , 2005, American journal of physiology. Lung cellular and molecular physiology.

[40]  Ze'ev Ronai,et al.  Role of redox potential and reactive oxygen species in stress signaling , 1999, Oncogene.

[41]  J. Moss,et al.  Mitogen-activated Protein Kinases Mediate Activator Protein-1-dependent Human Inducible Nitric-oxide Synthase Promoter Activation* , 2001, The Journal of Biological Chemistry.

[42]  I. Adcock,et al.  Ozone induction of cytokine‐induced neutrophil chemoattractant (CINC) and nuclear factor‐κb in rat lung: inhibition by corticosteroids , 1996, FEBS letters.

[43]  C. Scannell,et al.  Effects of ozone on normal and potentially sensitive human subjects. Part I: Airway inflammation and responsiveness to ozone in normal and asthmatic subjects. , 1997, Research report.

[44]  Hui Wang,et al.  p38 Inhibition attenuates the pro-inflammatory response to C-reactive protein by human peripheral blood mononuclear cells. , 2004, Journal of molecular and cellular cardiology.

[45]  C. Cross,et al.  Induction of stress proteins and MMP-9 by 0.8 ppm of ozone in murine skin. , 2003, Biochemical and biophysical research communications.

[46]  S. Gupta,et al.  Amelioration of ozone-induced lung injury by anti-tumor necrosis factor-alpha. , 2002, Toxicological sciences : an official journal of the Society of Toxicology.

[47]  B. Stripp,et al.  Inflammatory and antioxidant gene expression in C57BL/6J mice after lethal and sublethal ozone exposures. , 1999, Experimental lung research.

[48]  TylerZARUBIN,et al.  Activation and signaling of the p38 MAP kinase pathway , 2005 .

[49]  S. Rennard,et al.  Transforming growth factor-beta receptor type 1 (TGFbetaRI) kinase activity but not p38 activation is required for TGFbetaRI-induced myofibroblast differentiation and profibrotic gene expression. , 2006, Molecular Pharmacology.

[50]  L Bibbs,et al.  A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. , 1994, Science.

[51]  E. Gelfand,et al.  Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone. , 2004, American journal of respiratory cell and molecular biology.

[52]  Antonella Zanobetti,et al.  The effect of ozone and PM10 on hospital admissions for pneumonia and chronic obstructive pulmonary disease: a national multicity study. , 2006, American journal of epidemiology.

[53]  N. Holbrook,et al.  Cellular response to oxidative stress: Signaling for suicide and survival * , 2002, Journal of cellular physiology.

[54]  G. E. Jones,et al.  Mitogen-activated protein kinases mediate peroxynitrite-induced cell death in human bronchial epithelial cells. , 2003, American journal of physiology. Lung cellular and molecular physiology.

[55]  Y. Nasuhara,et al.  Inhibition of ozone-induced lung neutrophilia and nuclear factor-kappaB binding activity by vitamin A in rat. , 1999, European journal of pharmacology.

[56]  C. Sen.  Redox signaling and the emerging therapeutic potential of thiol antioxidants. , 1998, Biochemical pharmacology.

[57]  H. Genant,et al.  A selective p38 alpha mitogen-activated protein kinase inhibitor reverses cartilage and bone destruction in mice with collagen-induced arthritis. , 2006, The Journal of pharmacology and experimental therapeutics.

[58]  H. Boushey,et al.  O3-induced change in bronchial reactivity to methacholine and airway inflammation in humans. , 1986, Journal of applied physiology.