Kava use and risk of car crash injury: a population-based case control study in Fiji

Background The contribution from kava (a commonly consumed drink with sedative and anaesthetic properties) to the relatively high rates of road crashes in Pacific Island nations has received minimal research or policy attention. Aim/Objectives/Purpose To quantify the relationship between kava use before driving and car crash injuries in Viti Levu, Fiji. Methods A population-based case-control study was designed to include all cars involved in crashes where at least one occupant died or was hospitalised (case vehicles) and a random sample of cars being driven on roads in Viti Levu, Fiji (control vehicles). The drivers or their proxies in 154 case and 752control vehicles were administered structured questionnaires eliciting data on putative risk and protective factors including kava use. Results/Outcomes After adjustment for major confounders including alcohol use, consuming kava within 12 h of driving was associated with a five-fold increase in the odds of crash involvement (OR=5.23, 95% CI 2.16 to 12.7). Almost 20% of car crashes in Viti Levu could be attributed to the acute consumption of kava (Population Attributable Risk 19%, 95% CI 15% to 23%). Significance Kava use by drivers is a major contributor to serious injury-involved road crashes in Fiji and should be an explicit target in road safety strategies. While further studies are required to identify concentrations of kava and patterns of use that pose the greatest risk, this study illustrates the importance of investigating context-specific factors that account for a substantially greater burden of road crashes in some less-resourced settings than currently appreciated.

[1]  Junaid Abdul Razzak,et al.  Alcohol and marijuana use while driving--an unexpected crash risk in Pakistani commercial drivers: a cross-sectional survey , 2012, BMC Public Health.

[2]  E. Krug,et al.  The global burden of injuries. , 2000, American journal of public health.

[3]  C. Hocart,et al.  Chemical archaeology of kava, a potent brew. , 1993, Rapid communications in mass spectrometry : RCM.

[4]  Allen Abramson Drinking to mana and ethnicity: Trajectories of yaqona practice and symbolism in eastern Fiji , 2005 .

[5]  S Greenland,et al.  Modeling and variable selection in epidemiologic analysis. , 1989, American journal of public health.

[6]  G. Gururaj Alcohol and road traffic injuries in South Asia: challenges for prevention. , 2004, Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.

[7]  Anthony B. Zwi,et al.  ALCOHOL-RELATED TRAFFIC INJURIES AND FATALITIES IN DEVELOPING COUNTRIES: A CRITICAL REVIEW OF LITERATURE , 1995 .

[8]  R. Norman,et al.  The high burden of injuries in South Africa. , 2007, Bulletin of the World Health Organization.

[9]  Meleckidzedeck Khayesi,et al.  Road traffic injuries in Kenya: Magnitude, causes and status of intervention , 2003, Injury control and safety promotion.

[10]  Margaret M. Peden,et al.  World Report on Road Traffic Injury Prevention , 2004 .

[11]  S. Ameratunga,et al.  Development and piloting of the Fiji Injury Surveillance in Hospitals System (TRIP Project-1) , 2013, Injury.

[12]  J. Lemon,et al.  Acute effects of kava, alone or in combination with alcohol, on subjective measures of impairment and intoxication and on cognitive performance. , 1997, Drug and alcohol review.

[13]  Karen J. Brison CONSTRUCTING IDENTITY THROUGH CEREMONIAL LANGUAGE IN RURAL FIJI , 2001 .

[14]  R. Norton,et al.  Road-traffic injuries: confronting disparities to address a global-health problem , 2006, The Lancet.

[15]  A. Clough,et al.  The Neurobehavioural Effects of Kava , 2002, The Australian and New Zealand journal of psychiatry.

[16]  Gautam Roy,et al.  Epidemiological Study of Road Traffic Accident Cases: A Study from South India , 2004 .

[17]  P G Jackson,et al.  THE INFLUENCE OF CANNABIS AND ALCOHOL ON DRIVING , 2002 .

[18]  M. Woodward,et al.  Marijuana use and car crash injury. , 2005, Addiction.

[19]  A. Clough,et al.  Saccade and Cognitive Function in Chronic Kava Users , 2003, Neuropsychopharmacology.

[20]  B Ludes,et al.  Comparison of the prevalence of alcohol, cannabis and other drugs between 900 injured drivers and 900 control subjects: results of a French collaborative study. , 2003, Forensic science international.

[21]  M. Reich,et al.  The neglected epidemic: road traffic injuries in developing countries , 2002, BMJ : British Medical Journal.

[22]  M. Reich,et al.  Equity dimensions of road traffic injuries in low- and middle-income countries , 2003, Injury control and safety promotion.