Methylxanthines: toxicity to humans. 2. Caffeine.

[1]  P. Fried,et al.  Variability in caffeine consumption from coffee and tea: possible significance for epidemiological studies. , 1988, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[2]  J C Le Guennec,et al.  Delay in caffeine elimination in breast-fed infants. , 1987, Pediatrics.

[3]  B. Resch,et al.  [Effect of caffeine on the fetal heart]. , 1986, Orvosi hetilap.

[4]  R. Hoover,et al.  Methylxanthines and benign breast disease. , 1986, American journal of epidemiology.

[5]  A. Papatestas,et al.  Association of tumor differentiation with caffeine and coffee intake in women with breast cancer. , 1986, Surgery.

[6]  C. la Vecchia,et al.  Coffee consumption and the risk of breast cancer. , 1986, Surgery.

[7]  N. Boyd,et al.  A critique of the methodology of studies of benign breast disease and breast cancer risk. , 1986, Journal of the National Cancer Institute.

[8]  C. la Vecchia,et al.  Methylxanthine, alcohol-free diet and fibrocystic breast disease: a factorial clinical trial. , 1986, Surgery.

[9]  B B Fredholm,et al.  On the mechanism of action of theophylline and caffeine. , 2009, Acta medica Scandinavica.

[10]  P. Smits,et al.  Circulatory effects of coffee in relation to the pharmacokinetics of caffeine. , 1985, The American journal of cardiology.

[11]  J. Difranza,et al.  Smoking and drunk driving. , 1985, The New England journal of medicine.

[12]  C. Paré,et al.  Maturational changes of caffeine concentrations and disposition in infancy during maintenance therapy for apnea of prematurity: influence of gestational age, hepatic disease, and breast-feeding. , 1985, Pediatrics.

[13]  M. Lê.  Coffee consumption, benign breast disease, and breast cancer. , 1985, American journal of epidemiology.

[14]  J. T. Dalby,et al.  Will population decreases in caffeine consumption unveil attention deficit disorders in adults? , 1985, Medical hypotheses.

[15]  Pozniak Pc.  The carcinogenicity of caffeine and coffee: a review. , 1985 .

[16]  S. Shapiro,et al.  Breast cancer and the consumption of coffee. , 1985, American journal of epidemiology.

[17]  J. Wagner.  Theophylline. Pooled Michaelis-Menten parameters (Vmax and Km) and implications. , 1985, Clinical pharmacokinetics.

[18]  T. Takahashi,et al.  Effects of caffeine ingestion during pregnancy. , 1985, Gynecologic and obstetric investigation.

[19]  H. Miller,et al.  Effects of Chronic Caffeine Ingestion on Growth and Myocardial Function , 1985, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[20]  D T Chou,et al.  Caffeine tolerance: behavioral, electrophysiological and neurochemical evidence. , 1985, Life sciences.

[21]  C. Lacroix,et al.  [Theophylline-caffeine interaction in bronchial disease patients with cardiac and hepatic failure]. , 1985, Presse medicale.

[22]  M J Shirlow,et al.  A study of caffeine consumption and symptoms; indigestion, palpitations, tremor, headache and insomnia. , 1985, International journal of epidemiology.

[23]  C. Hill.  Coffee consumption and cholesterol concentrations , 1985 .

[24]  G. D. Timmons,et al.  Objectively Measured Hyperactivity—II. Caffeine and Amphetamine Effects , 1985, Journal of clinical pharmacology.

[25]  C. la Vecchia,et al.  Benign breast disease and consumption of beverages containing methylxanthines. , 1985, Journal of the National Cancer Institute.

[26]  J. Garriott,et al.  Five cases of fatal overdose from caffeine-containing "look-alike" drugs. , 1985, Journal of analytical toxicology.

[27]  D. Morgan,et al.  Influence of chronic dosing on theophylline clearance. , 1985, British journal of clinical pharmacology.

[28]  E. Ron,et al.  A case-control study of caffeine and methylxanthines in benign breast disease. , 1985, JAMA.

[29]  B. Modan,et al.  Coffee and methylxanthines and breast cancer: a case-control study. , 1985, Journal of the National Cancer Institute.

[30]  T. Montague,et al.  The effect of caffeine on cardiac rate, rhythm, and ventricular repolarization. Analysis of 18 normal subjects and 18 patients with primary ventricular dysrhythmia. , 1985, Chest.

[31]  D. Charney,et al.  Increased anxiogenic effects of caffeine in panic disorders. , 1985, Archives of general psychiatry.

[32]  J. I. Levy,et al.  Plasma theophylline concentrations, six minute walking distances, and breathlessness in patients with chronic airflow obstruction , 1985, British medical journal.

[33]  A. Ferguson.  Should Pregnant Women Avoid Caffeine? , 1985 .

[34]  J. Ryu.  Caffeine in human milk and in serum of breast-fed infants. , 1985, Developmental pharmacology and therapeutics.

[35]  E. Renner,et al.  High-performance liquid chromatographic determination of dimethylxanthine metabolites of caffeine in human plasma. , 1985, Journal of chromatography.

[36]  J. Ryu.  Effect of maternal caffeine consumption on heart rate and sleep time of breast-fed infants. , 1985, Developmental pharmacology and therapeutics.

[37]  P. Fried,et al.  Maternal caffeine use before, during and after pregnancy and effects upon offspring. , 1985, Neurobehavioral toxicology and teratology.

[38]  M. Shirlow,et al.  Caffeine consumption and serum cholesterol levels. , 1984, International journal of epidemiology.

[39]  R. Levy,et al.  Unsuspected Caffeine Toxicity Complicating Theophylline Therapy , 1984, Human toxicology.

[40]  D R Ismond,et al.  Behavioral effects of caffeine in children. Relationship between dietary choice and effects of caffeine challenge. , 1984, Archives of general psychiatry.

[41]  R. Post,et al.  Increased sensitivity to caffeine in patients with panic disorders. Preliminary evidence. , 1984, Archives of general psychiatry.

[42]  M. King,et al.  Risk factors for benign breast disease: a case-control study of discordant twins. , 1984, American journal of epidemiology.

[43]  C. Bazil,et al.  Caffeine injection raises brain tryptophan level, but does not stimulate the rate of serotonin synthesis in rat brain. , 1984, Life sciences.

[44]  C. Dubray,et al.  [Caffeine poisoning in infants resulting from confusion between dosage forms. Apropos of 5 cases]. , 1984, Therapie.

[45]  L. Muhlbaier,et al.  Prospective study of "fibrocystic breast disease" and caffeine consumption. , 1984, Surgery.

[46]  M J Maloney,et al.  Caffeine toxicity as a cause of acute psychosis in anorexia nervosa. , 1984, The Journal of pediatrics.

[47]  H. Barr,et al.  Infant size at 8 months of age: relationship to maternal use of alcohol, nicotine, and caffeine during pregnancy. , 1984, Pediatrics.

[48]  V. Petkov,et al.  Effects of caffeine on aggressive behavior and avoidance learning of rats with isolation syndrome. , 1984, Methods and findings in experimental and clinical pharmacology.

[49]  M. Goldberg,et al.  Caffeine and hypertension. , 1984, The American journal of medicine.

[50]  J. Kelsey,et al.  Caffeine consumption and fibrocystic breast disease: a case-control epidemiologic study. , 1984, Journal of the National Cancer Institute.

[51]  A. Becker,et al.  The bronchodilator effects and pharmacokinetics of caffeine in asthma. , 1984, The New England journal of medicine.

[52]  S. Snyder,et al.  Adenosine as a Mediator of the Behavioral Effects of Xanthines , 1984 .

[53]  R. Wurtman,et al.  Caffeine and the Cardiovascular Effects of Physiological Levels of Adenosine , 1984 .

[54]  J. J. Barone,et al.  Human Consumption of Caffeine , 1984 .

[55]  H. Grice.  The Carcinogenic Potential of Caffeine , 1984 .

[56]  Eliot R. Spindel,et al.  Neuroendocrine Effects of Caffeine in Rat and Man , 1984 .

[57]  A. Leviton.  Epidemiologic Studies of Birth Defects , 1984 .

[58]  W. Scott,et al.  The Teratogenic Potential of Caffeine in Laboratory Animals , 1984 .

[59]  Maternal coffee drinking and unusually high concentrations of caffeine in the newborn. , 1984, Journal of toxicology. Clinical toxicology.

[60]  M. Arnaud,et al.  Caffeine: A Model Compound for Measuring Liver Function , 1984, Hepatology.

[61]  I. Tebbutt,et al.  Caffeine, theophylline and theobromine in pregnancy. , 1984, Biological research in pregnancy and perinatology.

[62]  M. Puukka,et al.  The effect of caffeine on placental and fetal blood flow in human pregnancy. , 1983, American journal of obstetrics and gynecology.

[63]  T. Turmen,et al.  Effect of caffeine on control of breathing in infantile apnea. , 1983, The Journal of pediatrics.

[64]  R. Mathew,et al.  Caffeine and Cerebral Blood Flow , 1983, British Journal of Psychiatry.

[65]  J. D. Lane.  Caffeine and cardiovascular responses to stress. , 1983, Psychosomatic medicine.

[66]  D. B. Clayson,et al.  Book reviewCarcinogens and mutagens in the environment: Vol. 1. Food Products. H.F. Stich (Ed.), CRC Press Inc., Boca Raton, FL, U.S.A. (US$89.50; outside U.S., $99.50) , 1983 .

[67]  R. Labow.  Effects of caffeine being studied for treatment of apnea in newborns. , 1983, Canadian Medical Association journal.

[68]  J. Papp,et al.  Effects of caffeine on the fetal heart. , 1983, American journal of obstetrics and gynecology.

[69]  D Robertson,et al.  The health consequences of caffeine. , 1983, Annals of internal medicine.

[70]  C. Leier,et al.  The arrhythmogenic effects of caffeine in human beings. , 1983, The New England journal of medicine.

[71]  L. Hendeles,et al.  Current concepts. Slow-release theophylline rationale and basis for product selection. , 1983, The New England journal of medicine.

[72]  J Patel,et al.  Chronic caffeine consumption increases the number of brain adenosine receptors. , 1983, Life sciences.

[73]  J. Sours,et al.  Case reports of anorexia nervosa and caffeinism. , 1983, The American journal of psychiatry.

[74]  J. Steinberg,et al.  Effects of caffeine on human aggressive behavior , 1983, Psychiatry Research.

[75]  J L Brazier,et al.  Pharmacokinetics of caffeine during and after pregnancy. , 1983, Developmental pharmacology and therapeutics.

[76]  T. J. Haley,et al.  Metabolism and pharmacokinetics of theophylline in human neonates, children, and adults. , 1983, Drug metabolism reviews.

[77]  Boulenger Jp,et al.  Caffeine consumption and anxiety: preliminary results of a survey comparing patients with anxiety disorders and normal controls. , 1982 .

[78]  G. A. Nolen.  A reproduction/teratology study of brewed and instant decaffeinated coffees. , 1982, Journal of toxicology and environmental health.

[79]  N. Benowitz,et al.  Massive catecholamine release from caffeine poisoning. , 1982, JAMA.

[80]  W. Parsons,et al.  Delayed elimination of caffeine by women in the last 2 weeks of pregnancy. , 1982, Canadian Medical Association journal.

[81]  M. P. Lachance.  THE PHARMACOLOGY AND TOXICOLOGY OF CAFFEINE , 1982 .

[82]  S. Graham,et al.  Caffeine consumption and benign breast disease: a case-control comparison. , 1982, American journal of public health.

[83]  W. Hoff.  CAFFEINE IN PREGNANCY , 1982, The Lancet.

[84]  W. Pierson,et al.  Altered theophylline clearance during an influenza B outbreak. , 1982, Pediatrics.

[85]  A. Pradalier,et al.  Pharmacokinetics of theophylline in night-workers. , 1982, British journal of clinical pharmacology.

[86]  S. Shapiro,et al.  Selected Birth Defects in Relation to Caffeine‐Containing Beverages , 1982, JAMA.

[87]  T. K. Hunt,et al.  Effects of caffeine-free diet on benign breast disease: a randomized trial. , 1982, Surgery.

[88]  B. Rosner,et al.  No association between coffee consumption and adverse outcomes of pregnancy. , 1982, The New England journal of medicine.

[89]  Tarka Sm.  The toxicology of cocoa and methylxanthines: A review of the literature , 1982 .

[90]  M. Dumas,et al.  Systematic determination of caffeine plasma concentrations at birth in preterm and full-term infants. , 1982, Developmental pharmacology and therapeutics.

[91]  T. Black,et al.  A study of the teratogenic potential of caffeine given by oral intubation to rats , 1981 .

[92]  S. Riegelman,et al.  Metabolism of theophylline to caffeine in adults. , 1981, Research communications in chemical pathology and pharmacology.

[93]  K. Rothman,et al.  Coffee and tea consumption and breast disease. , 1981, Surgery.

[94]  H. Abou-Issa,et al.  Biochemical subgrouping of benign breast disease to define premalignant potential. , 1981, Surgery.

[95]  T. Turmen,et al.  Relationship of dose and plasma concentrations of caffeine and ventilation in neonatal apnea. , 1981, Seminars in perinatology.

[96]  H. Abou-Issa,et al.  Clinical and biochemical studies on methylxanthine-related fibrocystic breast disease. , 1981, Surgery.

[97]  M. Jacobson,et al.  COFFEE AND BIRTH DEFECTS , 1981, The Lancet.

[98]  R. Wiggins,et al.  A possible effect of the methylxanthines caffeine, theophylline and aminophylline on postnatal myelination of the rat brain , 1981, Brain Research.

[99]  S. Gart,et al.  Measuring the effect of caffeine restriction on fibrocystic breast disease: the role of graphic stress telethermometry as an objective monitor of disease. , 1981, The Journal of reproductive medicine.

[100]  S H Snyder,et al.  Adenosine receptors and behavioral actions of methylxanthines. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[101]  A H Neims,et al.  Prolonged half-life of caffeine in healthy tem newborn infants. , 1981, The Journal of pediatrics.

[102]  G. A. Nolen.  The effect of brewed and instant coffee on reproduction and teratogenesis in the rat. , 1981, Toxicology and applied pharmacology.

[103]  R Workman,et al.  Tolerance to the humoral and hemodynamic effects of caffeine in man. , 1981, The Journal of clinical investigation.

[104]  K Gilliland,et al.  Ad lib caffeine consumption, symptoms of caffeinism, and academic performance. , 1981, The American journal of psychiatry.

[105]  J. J. Jeffries,et al.  Should psychiatric patients drink coffee? , 1981, Canadian Medical Association journal.

[106]  M S Buchsbaum,et al.  Acute effects of caffeine in normal prepubertal boys. , 1981, The American journal of psychiatry.

[107]  C. Schlatter,et al.  The Effect of Pregnancy on the Pharmacokinetics of Caffeine , 1981 .

[108]  M. J. Maisels,et al.  The metabolic effects of caffeine in the newborn infant. , 1981, Pediatric pharmacology.

[109]  S. Heyden.  Coffee and fibrocystic breast disease. , 1980, Surgery.

[110]  D T Reay,et al.  Deaths related to coffee enemas. , 1980, JAMA.

[111]  J. Grygiel,et al.  Effect of age on patterns of theophylline metabolism , 1980, Clinical pharmacology and therapeutics.

[112]  B C White,et al.  Anxiety and muscle tension as consequences of caffeine withdrawal. , 1980, Science.

[113]  A. V. Peterson,et al.  Risk of breast cancer in women with benign breast disease. , 1980, Journal of the National Cancer Institute.

[114]  P. Czajka,et al.  Acute caffeine overdose in the neonate. , 1980, American journal of diseases of children.

[115]  S. Schenker,et al.  Impaired elimination of caffeine by oral contraceptive steroids. , 1980, The Journal of laboratory and clinical medicine.

[116]  B E Statland,et al.  Serum caffeine half-lives. Healthy subjects vs. patients having alcoholic hepatic disease. , 1980, American journal of clinical pathology.

[117]  R. Gilbert.  Caffeine: Overview and anthology , 1980 .

[118]  M B McGee,et al.  Caffeine poisoning in a 19-year-old female. , 1980, Journal of forensic sciences.

[119]  W. Dodson,et al.  Caffeine secretion into breast milk. , 1979, Archives of disease in childhood.

[120]  R. D. Dorand,et al.  Caffeine toxicity in a neonate . , 1979, Pediatrics.

[121]  Webster Dj,et al.  Caffeine, cyclic nucleotides, and breast disease. , 1979, Surgery.

[122]  R. Royer,et al.  Caffeine, a metabolite of theophylline during the treatment of apnea in the premature infant. , 1979, The Journal of pediatrics.

[123]  P. Loughnan,et al.  Pharmacokinetic profile of caffeine in the premature newborn infant with apnea. , 1979, The Journal of pediatrics.

[124]  L. Soyka.  Effects of methylxanthines on the fetus. , 1979, Clinics in perinatology.

[125]  J. Brazier,et al.  Plasma xanthine levels in low birthweight infants treated or not treated with theophylline. , 1979, Archives of disease in childhood.

[126]  A W Peck,et al.  Effects of caffeine and cyclizine alone and in combination on human performance, subjective effects and EEG activity. , 1979, British journal of clinical pharmacology.

[127]  John F. Greden,et al.  Coffee, Tea and You , 1979 .

[128]  D. Graham,et al.  Caffeine--its identity, dietary sources, intake and biological effects. , 2009, Nutrition reviews.

[129]  E. Mikkelsen,et al.  Caffeine and schizophrenia. , 1978, The Journal of clinical psychiatry.

[130]  J. Duffy,et al.  No relation between coffee and blood pressure. , 1978, The New England journal of medicine.

[131]  J. Adams,et al.  Monoamine synthesis and caffeine-induced locomotor activity , 1978, Neuropharmacology.

[132]  D Robertson,et al.  Effects of caffeine on plasma renin activity, catecholamines and blood pressure. , 1978, The New England journal of medicine.

[133]  J. R. Lodge,et al.  Caffeine and pregnancy. A retrospective survey. , 1977, Postgraduate medicine.

[134]  J. Sullivan.  Caffeine poisoning in an infant , 1977 .

[135]  T. Gunn,et al.  Efficacy of caffeine in treatment of apnea in the low-birth-weight infant. , 1977, The Journal of pediatrics.

[136]  W. Kannel,et al.  Coffee and cardiovascular disease. , 1974, The Medical letter on drugs and therapeutics.

[137]  R. H. Cravey,et al.  A fatal ingestion of caffeine. , 1977, Clinical toxicology.

[138]  Winstead Dk,et al.  Coffee consumption among psychiatric inpatients. , 1976 .

[139]  J. Aranda.  Coffee, Tea, and Apnea-Reply , 1976 .

[140]  M. Deutsch.  Letter: Coffee, tea, and apnea. , 1976, JAMA.

[141]  C. Hennekens,et al.  Coffee drinking and death due to coronary heart disease. , 1976, The New England journal of medicine.

[142]  R. Gilbert,et al.  Caffeine content of beverages as consumed. , 1976, Canadian Medical Association journal.

[143]  J. Mace,et al.  Caffeine (no-doz) poisoning in childhood. , 1976, The Western journal of medicine.

[144]  M. Thorogood,et al.  COFFEE-DRINKING AND MYOCARDIAL INFARCTION , 1975, The Lancet.

[145]  P. Spano,et al.  Accumulation of caffeine and its metabolites in rat fetal brain and liver. , 1975, Pharmacological research communications.

[146]  M. Horning,et al.  Drug metabolism in the human neonate. , 1975, Life sciences.

[147]  J. Garriott,et al.  Lethal caffeine poisoning in a child. , 1974, Forensic science.

[148]  J. Greden,et al.  Anxiety or caffeinism: a diagnostic dilemma. , 1974, The American journal of psychiatry.

[149]  A. Siegelaub,et al.  Coffee drinking prior to acute myocardial infarction. Results from the Kaiser-Permanente Epidemiologic Study of Myocardial Infarction. , 1973, JAMA.

[150]  J. Mulvihill.  Caffeine as teratogen and mutagen. , 1973, Teratology.

[151]  S. Shapiro,et al.  Coffee and myocardial infarction. , 1973, The New England journal of medicine.

[152]  R. Hill.  Drugs ingested by pregnant women , 1973, Clinical pharmacology and therapeutics.

[153]  R B Forney,et al.  Report of a human fatality due to caffeine. , 1973, Journal of forensic sciences.

[154]  S. Hayreh,et al.  Coffee drinking and acute myocardial infarction. , 1973, Lancet.

[155]  S. Bellet,et al.  The effect of caffeine on free fatty acids. , 1965, Archives of internal medicine.

[156]  Margaret C. Mc Manamy,et al.  Caffeine Intoxication: Report of a Case the Symptoms of Which Amounted to a Psychosis , 1936 .