Vascular, Cardiovascular, and Neurological Actions of Parathyroid-Related Protein

[1]  B. Sicari,et al.  Cellular Mechanism Through Which Parathyroid Hormone–Related Protein Induces Proliferation in Arterial Smooth Muscle Cells: Definition of an Arterial Smooth Muscle PTHrP/p27kip1 Pathway , 2006, Circulation research.

[2]  J. Foley,et al.  Parathyroid hormone hormone-related protein and the PTH receptor regulate angiogenesis of the skin. , 2006, The Journal of investigative dermatology.

[3]  A. Broadus,et al.  Induction of parathyroid hormone‐related peptide following peripheral nerve injury: Role as a modulator of Schwann cell phenotype , 2006, Glia.

[4]  H. Kronenberg PTHrP and Skeletal Development , 2006, Annals of the New York Academy of Sciences.

[5]  J. Whitfield Osteogenic PTHs and vascular ossification—Is there a danger for osteoporotics? , 2005, Journal of cellular biochemistry.

[6]  A. F. Stewart,et al.  Parathyroid Hormone–Related Protein as a Regulator of pRb and the Cell Cycle in Arterial Smooth Muscle , 2004, Circulation.

[7]  R. Ratan,et al.  Novel changes in gene expression following axotomy of a sympathetic ganglion: a microarray analysis. , 2004, Journal of neurobiology.

[8]  P. Kostyuk,et al.  Parathyroid hormone enhances calcium current in snail neurones — Simulation of the effect by phorbol esters , 1992, Pflügers Archiv.

[9]  M. Musso,et al.  The vasodilator action of parathyroid hormone fragments on isolated perfused rat kidney , 1989, Naunyn-Schmiedeberg's Archives of Pharmacology.

[10]  P. Esbrit,et al.  Possible Role of Parathyroid Hormone–Related Protein as a Proinflammatory Cytokine in Atherosclerosis , 2003, Stroke.

[11]  E. Gruenstein,et al.  Midgestational lethality in mice lacking the parathyroid hormone (PTH)/PTH-related peptide receptor is associated with abrupt cardiomyocyte death. , 2003, Endocrinology.

[12]  R. Terkeltaub,et al.  Parathyroid hormone–related peptide is a naturally occurring, protein kinase A–dependent angiogenesis inhibitor , 2002, Nature Medicine.

[13]  P. Wood,et al.  N-Cadherin Mediates Axon-Aligned Process Growth and Cell–Cell Interaction in Rat Schwann Cells , 2002, The Journal of Neuroscience.

[14]  Yoshiya Tanaka,et al.  The mutual regulation of arginine-vasopressin and PTHrP secretion in dissociated supraoptic neurons. , 2002, Endocrinology.

[15]  L. Kaczmarek,et al.  Endogenous parathyroid hormone-related protein functions as a neuroprotective agent , 2002, Brain Research.

[16]  R. Terkeltaub,et al.  Parathyroid hormone-related protein induces interleukin 8 production by prostate cancer cells via a novel intracrine mechanism not mediated by its classical nuclear localization sequence. , 2001, Cancer research.

[17]  J. Morgan,et al.  Differential and Prolonged Expression of Fos–lacZ and Jun–lacZ in Neurons, Glia, and Muscle Following Sciatic Nerve Damage , 2001, Experimental Neurology.

[18]  N. Iwahori,et al.  Parathyroid hormone-related peptide is a potent tumor angiogenic factor. , 2000, Endocrinology.

[19]  Y. Ouchi,et al.  Expression of parathyroid hormone-related protein in human and experimental atherosclerotic lesions: functional role in arterial intimal thickening. , 2000, Atherosclerosis.

[20]  D. Pette,et al.  Parathyroid hormone-related protein is rapidly up-regulated in blood vessels of rat skeletal muscle by low-frequency stimulation , 1999, Pflügers Archiv.

[21]  T. Usdin,et al.  TIP39: a new neuropeptide and PTH2-receptor agonist from hypothalamus , 1999, Nature Neuroscience.

[22]  A. Broadus,et al.  Parathyroid hormone-related protein protects against kainic acid excitotoxicity in rat cerebellar granule cells by regulating L-type channel calcium flux , 1999, Neuroscience Letters.

[23]  S. Hall The Biology of Chronically Denervated Schwann Cells , 1999, Annals of the New York Academy of Sciences.

[24]  H. Lang,et al.  Parathyroid Hormone-Related Protein in Rat Penis: Expression, Localization, and Effect on Cavernosal Pressure1. , 1999, Endocrinology.

[25]  T. Clemens,et al.  Vasorelaxant properties of parathyroid hormone-related protein in the mouse: evidence for endothelium involvement independent of nitric oxide formation. , 1999, Endocrinology.

[26]  T. Clemens,et al.  Printed in U.S.A. Copyright © 1999 by The Endocrine Society Reduced Blood Pressure and Increased Sensitivity of the Vasculature to Parathyroid Hormone-Related Protein (PTHrP) in Transgenic Mice Overexpressing the PTH/ PTHrP Receptor in Vascular Smooth Mus , 2022 .

[27]  M. Brines,et al.  Parathyroid hormone-related protein markedly potentiates depolarization-induced catecholamine release in PC12 cells via L-type voltage-sensitive Ca2+ channels. , 1999, Endocrinology.

[28]  X. Wu,et al.  Pharmacomechanical coupling: the role of calcium, G-proteins, kinases and phosphatases. , 1999, Reviews of physiology, biochemistry and pharmacology.

[29]  N. Amizuka,et al.  Inactivating mutation in the human parathyroid hormone receptor type 1 gene in Blomstrand chondrodysplasia. , 1998, Endocrinology.

[30]  H. Miyakawa,et al.  Activation of dihydropyridine sensitive Ca2+ channels in rat hippocampal neurons in culture by parathyroid hormone , 1998, Neuroscience Letters.

[31]  Denise S Walker,et al.  Subunit interaction sites in voltage-dependent Ca2+ channels: role in channel function , 1998, Trends in Neurosciences.

[32]  B. Lanske,et al.  Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development. , 1998, Development.

[33]  E. Nabel,et al.  Expression of cyclin-dependent kinase inhibitors in vascular disease. , 1998, Circulation research.

[34]  B. Lanske,et al.  Parathyroid hormone-related peptide (PTHrP) and parathyroid hormone (PTH)/PTHrP receptor. , 1998, Critical reviews in eukaryotic gene expression.

[35]  K. Schlüter,et al.  Cardiovascular actions of parathyroid hormone and parathyroid hormone-related peptide. , 1998, Cardiovascular research.

[36]  Y. Ouchi,et al.  Amino-terminal fragment (1-34) of parathyroid hormone-related protein inhibits migration and proliferation of cultured vascular smooth muscle cells. , 1998, Atherosclerosis.

[37]  S. Yamamoto,et al.  Centrally administered parathyroid hormone (PTH)-related protein(1-34) but not PTH(1-34) stimulates arginine-vasopressin secretion and its messenger ribonucleic acid expression in supraoptic nucleus of the conscious rats. , 1998, Endocrinology.

[38]  A. F. Stewart,et al.  Opposing mitogenic and anti-mitogenic actions of parathyroid hormone-related protein in vascular smooth muscle cells: a critical role for nuclear targeting. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[39]  Keiko Tanaka,et al.  PTH-related peptide-like immunoreactivity in the median emminence, paraventricular and supraoptic nuclei in colchicine-treated rats , 1997, Brain Research.

[40]  S. Brennecke,et al.  Vascular effects of PTHrP (1-34) and PTH (1-34) in the human fetal-placental circulation. , 1997, Placenta.

[41]  G. Condorelli,et al.  Activation of cAMP–PKA signaling in vivo inhibits smooth muscle cell proliferation induced by vascular injury , 1997, Nature Medicine.

[42]  J. Golding,et al.  Effects of Extracellular Matrix Components on Axonal Outgrowth from Peripheral Nerves of Adult Animalsin Vitro , 1997, Experimental Neurology.

[43]  Y. Nishizawa,et al.  Parathyroid hormone-related peptide as a local regulator of vascular calcification. Its inhibitory action on in vitro calcification by bovine vascular smooth muscle cells. , 1997, Arteriosclerosis, thrombosis, and vascular biology.

[44]  A. Ogura,et al.  Activity-dependent Expression of Parathyroid Hormone-related Protein (PTHrP) in Rat Cerebellar Granule Neurons , 1997, The Journal of Biological Chemistry.

[45]  M. Brines,et al.  Parathyroid Hormone-related Peptide Is Produced by Cultured Cerebellar Granule Cells in Response to L-type Voltage-sensitive Ca2+ Channel Flux via a Ca2+/Calmodulin-dependent Kinase Pathway* , 1996, The Journal of Biological Chemistry.

[46]  T. Bonner,et al.  Distribution of parathyroid hormone-2 receptor messenger ribonucleic acid in rat. , 1996, Endocrinology.

[47]  B. Lanske,et al.  PTH/PTHrP Receptor in Early Development and Indian Hedgehog--Regulated Bone Growth , 1996, Science.

[48]  T. Clemens,et al.  Cell-specific signal transduction of parathyroid hormone (PTH)-related protein through stably expressed recombinant PTH/PTHrP receptors in vascular smooth muscle cells. , 1996, Endocrinology.

[49]  C. Idé Peripheral nerve regeneration , 1996, Neuroscience Research.

[50]  M. Nobuyoshi,et al.  Evidence that implicates the parathyroid hormone-related peptide in vascular stenosis. Increased gene expression in the intima of injured carotid arteries and human restenotic coronary lesions. , 1996, Arteriosclerosis, thrombosis, and vascular biology.

[51]  S. Scherer,et al.  Axon‐Schwann cell interactions regulate the expression of c‐jun in Schwann cells , 1996, Journal of neuroscience research.

[52]  J. Orloff,et al.  Defining the roles of parathyroid hormone-related protein in normal physiology. , 1996, Physiological reviews.

[53]  P. A. Friedman,et al.  Multiple calcium channel transcripts in rat osteosarcoma cells: selective activation of alpha 1D isoform by parathyroid hormone. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[54]  K. Ishibashi,et al.  Vascular actions of the calcium-regulating hormones. , 1995, Seminars in nephrology.

[55]  J. C. Chisholm,et al.  Signaling by N- and C-terminal sequences of parathyroid hormone-related protein in hippocampal neurons. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[56]  S. Lipton,et al.  Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function , 1995, Neuron.

[57]  B. Lanske,et al.  Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promote apoptotic cell death , 1995, Molecular and cellular biology.

[58]  D. Burkhoff,et al.  The hemodynamic basis for the cardiac effects of parathyroid hormone (PTH) and PTH-related protein. , 1995, Endocrinology.

[59]  T. Bonner,et al.  Identification and Functional Expression of a Receptor Selectively Recognizing Parathyroid Hormone, the PTH2 Receptor (*) , 1995, The Journal of Biological Chemistry.

[60]  A. Brickman,et al.  Desensitization of vascular tissue to parathyroid hormone and parathyroid hormone-related protein. , 1995, Endocrinology.

[61]  D. Mochly‐Rosen Localization of protein kinases by anchoring proteins: a theme in signal transduction. , 1995, Science.

[62]  M E Greenberg,et al.  Calcium signaling in neurons: molecular mechanisms and cellular consequences. , 1995, Science.

[63]  T. Clemens,et al.  Involvement of cell cycle and mitogen-activated pathways in induction of parathyroid hormone-related protein gene expression in rat aortic smooth muscle cells. , 1995, Endocrinology.

[64]  D. Weaver,et al.  Localization of parathyroid hormone-related peptide (PTHrP) and PTH/PTHrP receptor mRNAs in rat brain. , 1995, Brain research. Molecular brain research.

[65]  T. Ogihara,et al.  Role of parathyroid hormone-related protein in the proliferation of vascular smooth muscle cells. , 1995, Mineral and electrolyte metabolism.

[66]  Y. Ouchi,et al.  Parathyroid hormone-related protein reduces cytosolic free Ca2+ level and tension in rat aortic smooth muscle. , 1994, European journal of pharmacology.

[67]  R. A. Murphy,et al.  Cyclic nucleotide dependent relaxation in vascular smooth muscle. , 1994, Canadian journal of physiology and pharmacology.

[68]  T. Clemens,et al.  Parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptor and its messenger ribonucleic acid in rat aortic vascular smooth muscle cells and UMR osteoblast-like cells: cell-specific regulation by angiotensin-II and PTHrP. , 1994, Endocrinology.

[69]  K. Kurokawa,et al.  Synergistic stimulation of parathyroid hormone-related peptide gene expression by mechanical stretch and angiotensin II in rat aortic smooth muscle cells. , 1994, The Journal of biological chemistry.

[70]  M. Thiede,et al.  Parathyroid hormone-related protein: a regulated calcium-mobilizing product of the mammary gland. , 1994, Journal of dairy science.

[71]  S. Davis,et al.  Increased mammary blood flow in the lactating goat induced by parathyroid hormone‐related protein , 1994, Experimental physiology.

[72]  L. Deftos,et al.  Parathyroid hormone-related protein in the cardiovascular system. , 1994, Endocrinology.

[73]  T. Clemens,et al.  Mechanical stimuli induce vascular parathyroid hormone-related protein gene expression in vivo and in vitro. , 1994, Endocrinology.

[74]  Y. Ouchi,et al.  Immunocytochemical detection of parathyroid hormone-related protein in vascular endothelial cells. , 1994, Biochemical and biophysical research communications.

[75]  K. Gautvik,et al.  Parathyroid hormone-related protein is produced by cultured endothelial cells: a possible role in angiogenesis. , 1994, Biochemical and biophysical research communications.

[76]  L. Myatt,et al.  Vasodilator Effects of Parathyroid Hormone, Parathyroid Hormone-Related Protein, and Calcitonin Gene-Related Peptide in the Human Fetal-Placental Circulation , 1994, The Journal of the Society for Gynecologic Investigation: JSGI.

[77]  Jing Shan,et al.  Cardiovascular effects of human parathyroid hormone and parathyroid hormone-related peptide. , 1994, Journal of cardiovascular pharmacology.

[78]  S. Harvey,et al.  Parathyroid hormone: neural and neuroendocrine perspectives. , 1993, The Journal of endocrinology.

[79]  T. Clemens,et al.  Effects of N-terminal, midregion, and C-terminal parathyroid hormone-related peptides on adenosine 3',5'-monophosphate and cytoplasmic free calcium in rat aortic smooth muscle cells and UMR-106 osteoblast-like cells. , 1993, Endocrinology.

[80]  J. Hell,et al.  Differential phosphorylation of two size forms of the neuronal class C L-type calcium channel alpha 1 subunit. , 1993, The Journal of biological chemistry.

[81]  H. Jüppner,et al.  Parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acids are widely distributed in rat tissues. , 1993, Endocrinology.

[82]  P. Scarpace,et al.  Vasoactive properties of a parathyroid hormone-related protein in the rat aorta , 1993, Peptides.

[83]  T. Clemens,et al.  Angiotensin II regulates parathyroid hormone-related protein expression in cultured rat aortic smooth muscle cells through transcriptional and post-transcriptional mechanisms. , 1993, The Journal of biological chemistry.

[84]  A. Broadus,et al.  Stretch-induced parathyroid hormone-related peptide gene expression in the rat uterus. , 1992, The Journal of biological chemistry.

[85]  D. Bruns,et al.  Abundant expression of parathyroid hormone-related protein in human amnion and its association with labor. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[86]  M. Thiede,et al.  Parathyroid hormone-related protein in the rat urinary bladder: a smooth muscle relaxant produced locally in response to mechanical stretch. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[87]  R. Schleiffer Involvement of parathyroid hormone (PTH) in genetic models of hypertension. , 1992, Journal of endocrinological investigation.

[88]  T. Hökfelt Neuropeptides in perspective: The last ten years , 1991, Neuron.

[89]  T. Clemens,et al.  Abundant expression of parathyroid hormone-related protein in primary rat aortic smooth muscle cells accompanies serum-induced proliferation. , 1991, The Journal of clinical investigation.

[90]  L. Duong,et al.  Expression of the parathyroid hormone-related protein gene in the avian oviduct: potential role as a local modulator of vascular smooth muscle tension and shell gland motility during the egg-laying cycle. , 1991, Endocrinology.

[91]  P. Pang,et al.  Parathyroid hormone selectively inhibits L‐type calcium channels in single vascular smooth muscle cells of the rat. , 1991, The Journal of physiology.

[92]  Rui Wang,et al.  The effects of parathyroid hormone on L‐type voltage‐dependent calcium channel currents in vascular smooth muscle cells and ventricular myocytes are mediated by a cyclic AMP dependent mechanism , 1991, FEBS letters.

[93]  R. Lewanczuk,et al.  Parathyroid hypertensive factor, a circulating factor in animal and human hypertension. , 1991, American journal of hypertension.

[94]  K. Nicolaides,et al.  Parathyroid hormone-related peptide in normal human fetal development. , 1990, Journal of molecular endocrinology.

[95]  A. Broadus,et al.  Intrauterine occupancy controls expression of the parathyroid hormone-related peptide gene in preterm rat myometrium. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[96]  D. Choi,et al.  The calcium channel blocker nifedipine attenuates slow excitatory amino acid neurotoxicity. , 1990, Science.

[97]  J. Helwig,et al.  Binding of parathyroid hormone and parathyroid hormone-related protein to vascular smooth muscle of rabbit renal microvessels. , 1990, Endocrinology.

[98]  A. Broadus,et al.  Parathyroid hormone-related peptide gene is expressed in the mammalian central nervous system. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[99]  J. Shan,et al.  Specific inhibition of long-lasting, L-type calcium channels by synthetic parathyroid hormone. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[100]  J. Thompson,et al.  Parathyroid hormone as a smooth muscle relaxant. , 1989, Endocrine reviews.

[101]  A. Nana,et al.  Hypotension and cardiac stimulation due to the parathyroid hormone-related protein, humoral hypercalcemia of malignancy factor. , 1989, Endocrinology.

[102]  S. Harvey,et al.  Immunocytochemical distribution of PTH immunoreactivity in vertebrate brains. , 1988, The American journal of physiology.

[103]  D. McCarron,et al.  Calcium Metabolism in Experimental Hypertension , 1988, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[104]  G. Vlasuk,et al.  Synthetic tumor-derived human hypercalcemic factor exhibits parathyroid hormone-like vasorelaxation in renal arteries. , 1987, Biochemical and biophysical research communications.

[105]  R. Bunge Tissue culture observations relevant to the study of axon-Schwann cell interactions during peripheral nerve development and repair. , 1987, The Journal of experimental biology.

[106]  W. Cline,et al.  Parathyroid hormone-induced changes in cyclic nucleotide levels during relaxation of the rat aorta , 1987 .

[107]  J. Salzer,et al.  Studies of Schwann cell proliferation. I. An analysis in tissue culture of proliferation during development, Wallerian degeneration, and direct injury , 1980, The Journal of cell biology.

[108]  Charbon Ga Vasodilator action of parathyroid hormone used as bioassay. , 1969 .

[109]  G. A. Charbon A rapid and selective vasodialtor effect of parathyroid hormone. , 1968, European journal of pharmacology.

[110]  J. B. Collip,et al.  FURTHER STUDIES ON THE PHYSIOLOGICAL ACTION OF A PARATHYROID HORMONE , 1925 .