Optogenetic restoration of retinal ganglion cell activity in the living primate

[1]  Jennifer J. Hunter,et al.  Cellular-scale evaluation of induced photoreceptor degeneration in the living primate eye. , 2018, Biomedical optics express.

[2]  Khang T. Huynh,et al.  Functional architecture of the foveola revealed in the living primate , 2018, PloS one.

[3]  Tushar H. Ganjawala,et al.  A Robust Optomotor Assay for Assessing the Efficacy of Optogenetic Tools for Vision Restoration , 2018, Investigative ophthalmology & visual science.

[4]  Dirk Trauner,et al.  Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor , 2017, Nature Communications.

[5]  Philippe Hantraye,et al.  A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina. , 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

[6]  Kathleen A. Marshall,et al.  Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial , 2017, The Lancet.

[7]  G. Boynton,et al.  Learning to see again: biological constraints on cortical plasticity and the implications for sight restoration technologies , 2017, bioRxiv.

[8]  Olivier Marre,et al.  Red‐shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina , 2016, EMBO molecular medicine.

[9]  Evelyne Sernagor,et al.  Dampening Spontaneous Activity Improves the Light Sensitivity and Spatial Acuity of Optogenetic Retinal Prosthetic Responses , 2016, Scientific Reports.

[10]  David R. Williams,et al.  In Vivo Two-Photon Fluorescence Kinetics of Primate Rods and Cones , 2016, Investigative ophthalmology & visual science.

[11]  Michael H Berry,et al.  Optogenetic Vision Restoration Using Rhodopsin for Enhanced Sensitivity , 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

[12]  Siegrid Löwel,et al.  Restoring the ON Switch in Blind Retinas: Opto-mGluR6, a Next-Generation, Cell-Tailored Optogenetic Tool , 2015, PLoS biology.

[13]  Stefan R. Pulver,et al.  Independent Optical Excitation of Distinct Neural Populations , 2014, Nature Methods.

[14]  Stefan R. Pulver,et al.  Ultra-sensitive fluorescent proteins for imaging neuronal activity , 2013, Nature.

[15]  Deniz Dalkara,et al.  In Vivo–Directed Evolution of a New Adeno-Associated Virus for Therapeutic Outer Retinal Gene Delivery from the Vitreous , 2013, Science Translational Medicine.

[16]  E J Chichilnisky,et al.  Changes in physiological properties of rat ganglion cells during retinal degeneration. , 2011, Journal of neurophysiology.

[17]  David R Williams,et al.  Intravitreal injection of AAV2 transduces macaque inner retina. , 2011, Investigative ophthalmology & visual science.

[18]  Deniz Dalkara,et al.  Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

[19]  S. Stasheff,et al.  Emergence of sustained spontaneous hyperactivity and temporary preservation of OFF responses in ganglion cells of the retinal degeneration (rd1) mouse. , 2008, Journal of neurophysiology.

[20]  David R Williams,et al.  In vivo imaging of the fine structure of rhodamine-labeled macaque retinal ganglion cells. , 2008, Investigative ophthalmology & visual science.

[21]  A. Stockman,et al.  Human cone light adaptation: from behavioral measurements to molecular mechanisms. , 2006, Journal of vision.

[22]  B. Jones,et al.  Neural remodeling in retinal degeneration , 2003, Progress in Retinal and Eye Research.

[23]  R. M. C. So,et al.  Flow patterns of cross-flow around four equispaced cylinders at low reynolds number , 2003, J. Vis..

[24]  J. Pokorny,et al.  Sawtooth contrast sensitivity: Decrements have the edge , 1989, Vision Research.

[25]  Forrest L. Dimmick,et al.  The retina. The anatomy and the histology of the retina in man, ape, and monkey, including the consideration of visual functions, the history of physiological optics, and the histological laboratory technique. , 1944 .

[26]  S. Polyak,et al.  The retina : the anatomy and the histology of the retina in man, ape, and monkey, including the consideration of visual functions, the history of psysiological optics, and the histological laboratory technique , 1941 .