Domains of human topoisomerase I and associated functions.
暂无分享,去创建一个
[1] G. Ireton,et al. Reconstitution of human topoisomerase I by fragment complementation. , 1997, Journal of molecular biology.
[2] S. Shuman,et al. Histidine 265 Is Important for Covalent Catalysis by Vaccinia Topoisomerase and Is Conserved in All Eukaryotic Type I Enzymes* , 1997, The Journal of Biological Chemistry.
[3] P. Sharp,et al. Topoisomerase I enhances TFIID-TFIIA complex assembly during activation of transcription. , 1997, Genes & development.
[4] S. Shuman,et al. Mutations within a conserved region of vaccinia topoisomerase affect the DNA cleavage-religation equilibrium. , 1996, Journal of molecular biology.
[5] P. Brzoska,et al. Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae. , 1996, Genes & development.
[6] R. Sternglanz,et al. Cloning and characterization of the gene for the somatic form of DNA topoisomerase I from Xenopus laevis. , 1996, Nucleic acids research.
[7] B. Stillman,et al. Simian virus 40 large T antigen binds to topoisomerase I. , 1996, Virology.
[8] J. Fostel,et al. Identification of the gene encoding DNA topoisomerase I from Candida albicans. , 1996, FEMS microbiology letters.
[9] I. Chung,et al. cDNA cloning, expression, and chromosomal localization of Caenorhabditis elegans DNA topoisomerase I. , 1996, European journal of biochemistry.
[10] G. Ireton,et al. Biochemical and Biophysical Analyses of Recombinant Forms of Human Topoisomerase I (*) , 1996, The Journal of Biological Chemistry.
[11] J. Svejstrup,et al. Purification and characterization of human topoisomerase I mutants. , 1996, European journal of biochemistry.
[12] D. Kufe,et al. Identification of a Nucleolin Binding Site in Human Topoisomerase I (*) , 1996, The Journal of Biological Chemistry.
[13] J. Berger,et al. Structure and mechanism of DNA topoisomerase II , 1996, Nature.
[14] S. T. Taylor,et al. The creation of a camptothecin-sensitive Escherichia coli based on the expression of the human topoisomerase I. , 1995, Gene.
[15] J. Wang,et al. A 26 kDa yeast DNA topoisomerase I fragment: crystallographic structure and mechanistic implications. , 1995, Structure.
[16] B. Kilbey,et al. The gene encoding topoisomerase I from the human malaria parasite Plasmodium falciparum. , 1995, Gene.
[17] M. Bjornsti,et al. SCT1 mutants suppress the camptothecin sensitivity of yeast cells expressing wild-type DNA topoisomerase I. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[18] Y. Pommier,et al. Eukaryotic DNA topoisomerases I. , 1995, Biochimica et biophysica acta.
[19] M. Bjornsti,et al. A Camptothecin-resistant DNA Topoisomerase I Mutant Exhibits Altered Sensitivities to Other DNA Topoisomerase Poisons (*) , 1995, The Journal of Biological Chemistry.
[20] S. Shuman,et al. Mutational analysis of vaccinia DNA topoisomerase defines amino acid residues essential for covalent catalysis. , 1994, The Journal of biological chemistry.
[21] Y. Pommier,et al. Saintopin, a dual inhibitor of DNA topoisomerases I and II, as a probe for drug-enzyme interactions. , 1994, The Journal of biological chemistry.
[22] D. Gerhold,et al. The topoisomerase I gene from Ustilago maydis: sequence, disruption and mutant phenotype. , 1994, Nucleic acids research.
[23] N. Zini,et al. Discrete localization of different DNA topoisomerases in HeLa and K562 cell nuclei and subnuclear fractions. , 1994, Experimental cell research.
[24] D. Kufe,et al. Identification of a mutant human topoisomerase I with intact catalytic activity and resistance to 9-nitro-camptothecin. , 1994, The Journal of biological chemistry.
[25] Alfonso Mondragón,et al. Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I , 1994, Nature.
[26] R. Roeder,et al. Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[27] L. Liu,et al. Interaction between replication forks and topoisomerase I-DNA cleavable complexes: studies in a cell-free SV40 DNA replication system. , 1993, Cancer research.
[28] Y. Pommier,et al. Cloning of Chinese hamster DNA topoisomerase I cDNA and identification of a single point mutation responsible for camptothecin resistance. , 1993, The Journal of biological chemistry.
[29] K W Kohn,et al. Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin. , 1993, Nucleic acids research.
[30] M. Bjornsti,et al. Mechanisms of camptothecin resistance in yeast DNA topoisomerase I mutants. , 1993, The Journal of biological chemistry.
[31] D. Reinberg,et al. DNA topoisomerase I is involved in both repression and activation of transcription , 1993, Nature.
[32] J. Wang,et al. Camptothecin resistance from a single mutation changing glycine 363 of human DNA topoisomerase I to cysteine. , 1993, Cancer research.
[33] R. Laskey,et al. Nuclear shuttling: The default pathway for nuclear proteins? , 1993, Cell.
[34] L. Kühn,et al. Nuclear export of proteins: The role of nuclear retention , 1993, Cell.
[35] P. Traktman,et al. Biochemical analysis of mutant alleles of the vaccinia virus topoisomerase I carrying targeted substitutions in a highly conserved domain. , 1993, The Journal of biological chemistry.
[36] E. Nigg,et al. Protein localization to the nucleolus: a search for targeting domains in nucleolin. , 1993, Journal of cell science.
[37] A. Andersen,et al. Eukaryotic topoisomerase I-mediated cleavage requires bipartite DNA interaction. Cleavage of DNA substrates containing strand interruptions implicates a role for topoisomerase I in illegitimate recombination. , 1993, The Journal of biological chemistry.
[38] J. Champoux,et al. Analysis of the biased distribution of topoisomerase I break sites on replicating simian virus 40 DNA. , 1993, Journal of molecular biology.
[39] G. Fink,et al. A novel mutation in DNA topoisomerase I of yeast causes DNA damage and RAD9-dependent cell cycle arrest. , 1993, Genetics.
[40] J. Fostel,et al. Isolation and characterization of a gene encoding DNA topoisomerase I in Drosophila melanogaster. , 1992, Nucleic acids research.
[41] N. Saijo,et al. Detection of topoisomerase I gene point mutation in CPT-11 resistant lung cancer cell line. , 1992, Biochemical and biophysical research communications.
[42] J. Alsner,et al. Identification of an N-terminal domain of eukaryotic DNA topoisomerase I dispensable for catalytic activity but essential for in vivo function. , 1992, The Journal of biological chemistry.
[43] J. Champoux,et al. Overexpression of human topoisomerase I in baby hamster kidney cells: hypersensitivity of clonal isolates to camptothecin. , 1992, Cancer research.
[44] J. Svejstrup,et al. New technique for uncoupling the cleavage and religation reactions of eukaryotic topoisomerase I. The mode of action of camptothecin at a specific recognition site. , 1991, Journal of molecular biology.
[45] D. Wigley,et al. Crystal structure of an N-terminal fragment of the DNA gyrase B protein , 1991, Nature.
[46] Eric Patterson,et al. Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites , 1991, Nucleic Acids Res..
[47] R. Snapka,et al. Patterns of strongly protein-associated simian virus 40 DNA replication intermediates resulting from exposures to specific topoisomerase poisons. , 1990, Biochemistry.
[48] N. Osheroff,et al. Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers. , 1990, The EMBO journal.
[49] L. Liu,et al. Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons. , 1990, Cancer research.
[50] A. Amadei,et al. Regulation of the function of eukaryotic DNA topoisomerase I: analysis of the binding step and of the catalytic constants of topoisomerization as a function of DNA topology. , 1990, Biochemistry.
[51] S. Shuman,et al. Phenotypic selection and characterization of mutant alleles of a eukaryotic DNA topoisomerase I. , 1990, Genes & development.
[52] R. Herrera,et al. Rapid induction of c-fos transcription reveals quantitative linkage of RNA polymerase II and DNA topoisomerase I enzyme activities , 1990, Cell.
[53] J. Wang,et al. Expression of human DNA topoisomerase I in yeast cells lacking yeast DNA topoisomerase I: restoration of sensitivity of the cells to the antitumor drug camptothecin. , 1989, Cancer research.
[54] P. Kroeger,et al. Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene. , 1989, Nucleic acids research.
[55] J. Champoux,et al. The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I. , 1989, Nucleic acids research.
[56] K. Kohn,et al. Protein-linked DNA strand breaks induced in mammalian cells by camptothecin, an inhibitor of topoisomerase I. , 1989, Cancer research.
[57] L. Liu,et al. Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. , 1989, Cancer research.
[58] L. Liu,et al. DNA topoisomerase I-mediated DNA cleavage and cytotoxicity of camptothecin analogues. , 1989, Cancer research.
[59] R. Hertzberg,et al. On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex. , 1989, Biochemistry.
[60] J. Wang,et al. Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[61] E. Di Mauro,et al. Regulation of the function of eukaryotic DNA topoisomerase I: topological conditions for inactivity. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[62] J. Champoux,et al. Mapping in vivo topoisomerase I sites on simian virus 40 DNA: asymmetric distribution of sites on replicating molecules , 1989, Molecular and cellular biology.
[63] R. Sternglanz,et al. Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin. , 1988, Molecular pharmacology.
[64] J. Wang,et al. DNA topoisomerase-targeting antitumor drugs can be studied in yeast. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[65] E. Di Mauro,et al. Eukaryotic DNA topoisomerase I reaction is topology dependent. , 1988, Nucleic acids research.
[66] L. Bolund,et al. Sequence-dependent effect of camptothecin on human topoisomerase I DNA cleavage. , 1988, Journal of molecular biology.
[67] W. Earnshaw,et al. cDNA cloning of human DNA topoisomerase I: catalytic activity of a 67.7-kDa carboxyl-terminal fragment. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[68] J. Wang,et al. Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[69] T. Uemura,et al. Cloning and sequencing of Schizosaccharomyces pombe DNA topoisomerase I gene, and effect of gene disruption. , 1987, Nucleic acids research.
[70] J. Wang,et al. Expression of yeast DNA topoisomerase I can complement a conditional-lethal DNA topoisomerase I mutation in Escherichia coli. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[71] J. Wang,et al. Supercoiling of the DNA template during transcription. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[72] S. Crooke,et al. Relationship between the intracellular effects of camptothecin and the inhibition of DNA topoisomerase I in cultured L1210 cells. , 1987, Cancer research.
[73] John T. Lis,et al. Topoisomerase I interacts with transcribed regions in Drosophila cells , 1986, Cell.
[74] R. Hertzberg,et al. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. , 1985, The Journal of biological chemistry.
[75] J. Wang,et al. Cloning of yeast TOP1, the gene encoding DNA topoisomerase I, and construction of mutants defective in both DNA topoisomerase I and DNA topoisomerase II. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[76] R. Sternglanz,et al. Cloning, characterization, and sequence of the yeast DNA topoisomerase I gene. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[77] O. Westergaard,et al. A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in tetrahymena R-chromatin , 1985, Cell.
[78] M. Muller. Quantitation of eukaryotic topoisomerase I reactivity with DNA. Preferential cleavage of supercoiled DNA. , 1985, Biochimica et biophysica acta.
[79] J. Wang,et al. Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[80] R. Burgess,et al. Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA. , 1984, Nucleic acids research.
[81] M. Olson,et al. Interaction of nucleolar phosphoprotein C23 with cloned segments of rat ribosomal deoxyribonucleic acid. , 1983, Biochemistry.
[82] L. Liu,et al. Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[83] J. Champoux,et al. Purification and characterization of the DNA untwisting enzyme from rat liver. , 1976, Biochemistry.
[84] W. Keller. Characterization of purified DNA-relaxing enzyme from human tissue culture cells. , 1975, Proceedings of the National Academy of Sciences of the United States of America.
[85] Leroy F. Liu. DNA Topoisomerases : biochemistry and molecular biology , 1994 .
[86] T. Hsieh,et al. Structure of eukaryotic type I DNA topoisomerase. , 1994, Advances in pharmacology.
[87] J. Nitiss. Roles of DNA topoisomerases in chromosomal replication and segregation. , 1994, Advances in pharmacology.
[88] L. Liu,et al. Roles of DNA topoisomerases in transcription. , 1994, Advances in pharmacology.
[89] M. Gellert,et al. The biochemistry and biology of DNA gyrase. , 1994, Advances in pharmacology.
[90] R. Laskey,et al. Nuclear targeting sequences--a consensus? , 1991, Trends in biochemical sciences.
[91] Nicholas R. Cozzarelli,et al. DNA topology and its biological effects , 1990 .
[92] R. Sternglanz,et al. Need for DNA topoisomerase activity as a swivel for DNA replication for transcription of ribosomal RNA , 1987, Nature.