Enhancement of HIV-1 infection and intestinal CD4+ T cell depletion ex vivo by gut microbes altered during chronic HIV-1 infection
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Daniel N. Frank | Kejun Guo | M. McCarter | M. Santiago | D. Frank | Cara C Wilson | Eric J. Lee | S. Dillon | Michael S. Harper | Mario L. Santiago | Cara C. Wilson | Stephanie M. Dillon | Andrew M. Donovan | Martin D. McCarter | K. Guo | Michael S Harper
[1] A. Keshavarzian,et al. A Compositional Look at the Human Gastrointestinal Microbiome and Immune Activation Parameters in HIV Infected Subjects , 2014, PLoS pathogens.
[2] R P Johnson,et al. Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. , 1998, Science.
[3] G. Silvestri,et al. Microbial Translocation in the Pathogenesis of HIV Infection and AIDS , 2013, Clinical Microbiology Reviews.
[4] M. Paiardini. Th17 cells in natural SIV hosts , 2010, Current opinion in HIV and AIDS.
[5] W. Greene,et al. Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue , 2010, Cell.
[6] A. Kane,et al. Intestinal microbiota, microbial translocation, and systemic inflammation in chronic HIV infection. , 2015, The Journal of infectious diseases.
[7] S. Rhee,et al. Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4 , 1994, Journal of Virology.
[8] A. Gettie,et al. The Frequency of &agr;4&bgr;7high Memory CD4+ T Cells Correlates With Susceptibility to Rectal Simian Immunodeficiency Virus Infection , 2013, Journal of acquired immune deficiency syndromes.
[9] Xin Geng,et al. Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection , 2013, Nature.
[10] J. García,et al. Impact of highly active antiretroviral therapy initiation on CD4+ T-cell repopulation in duodenal and rectal mucosa , 2013, AIDS.
[11] S. Gianella,et al. An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia , 2014, Mucosal Immunology.
[12] Elmar Pruesse,et al. SINA: Accurate high-throughput multiple sequence alignment of ribosomal RNA genes , 2012, Bioinform..
[13] S. Nielsen,et al. Incomplete Immune Recovery in HIV Infection: Mechanisms, Relevance for Clinical Care, and Possible Solutions , 2012, Clinical & developmental immunology.
[14] M. Lederman,et al. Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment. , 2014, The Journal of infectious diseases.
[15] Handan Wand,et al. Plasma levels of soluble CD14 independently predict mortality in HIV infection. , 2011, The Journal of infectious diseases.
[16] K. Mansfield,et al. Dynamics of CCR5 Expression by CD4+ T Cells in Lymphoid Tissues during Simian Immunodeficiency Virus Infection , 2000, Journal of Virology.
[17] Mario Roederer,et al. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection , 2005, Nature.
[18] M. Herzberg,et al. Porphyromonas gingivalis Selectively Up-Regulates the HIV-1 Coreceptor CCR5 in Oral Keratinocytes1 , 2007, The Journal of Immunology.
[19] V. Piguet,et al. The role of human dendritic cells in HIV-1 infection. , 2015, The Journal of investigative dermatology.
[20] C. Mackay,et al. Enhanced levels of functional HIV-1 co-receptors on human mucosal T cells demonstrated using intestinal biopsy tissue , 2000, AIDS.
[21] M. Markowitz,et al. Erratum: Lack of mucosal immune reconstitution during prolonged treatment of acute and early HIV-1 infection (PloS Medicine 3,12 DOI:10.1371/journal.pmed. 0030484) , 2006 .
[22] A. Latorre,et al. Altered metabolism of gut microbiota contributes to chronic immune activation in HIV-infected individuals , 2014, Mucosal Immunology.
[23] M. Bocchino,et al. Expansion of CCR5+ CD4+ T-lymphocytes in the course of active pulmonary tuberculosis , 2004, European Respiratory Journal.
[24] Ryan D. Hernandez,et al. Dysbiosis of the Gut Microbiota Is Associated with HIV Disease Progression and Tryptophan Catabolism , 2013, Science Translational Medicine.
[25] T. van der Poll,et al. Patients with active tuberculosis have increased expression of HIV coreceptors CXCR4 and CCR5 on CD4(+) T cells. , 2001, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[26] M. Herzberg,et al. Plausibility of HIV-1 Infection of Oral Mucosal Epithelial Cells , 2011, Advances in dental research.
[27] M. McCarter,et al. Human Intestinal Lamina Propria CD1c+ Dendritic Cells Display an Activated Phenotype at Steady State and Produce IL-23 in Response to TLR7/8 Stimulation , 2010, The Journal of Immunology.
[28] I. Chen,et al. A Preponderance of CCR5+CXCR4+ Mononuclear Cells Enhances Gastrointestinal Mucosal Susceptibility to Human Immunodeficiency Virus Type 1 Infection , 2001, Journal of Virology.
[29] Natalie J Torok,et al. Molecular Characterization of Stool Microbiota in HIV-Infected Subjects by Panbacterial and Order-Level 16S Ribosomal DNA (rDNA) Quantification and Correlations With Immune Activation , 2011, Journal of acquired immune deficiency syndromes.
[30] M. Lederman,et al. Gut epithelial barrier dysfunction and innate immune activation predict mortality in treated HIV infection. , 2014, The Journal of infectious diseases.
[31] S. Bixler,et al. Loss and Dysregulation of Th17 Cells during HIV Infection , 2013, Clinical & developmental immunology.
[32] F. Chirdo,et al. Immunomodulatory dendritic cells in intestinal lamina propria , 2005, European journal of immunology.
[33] Pelin Yilmaz,et al. The SILVA ribosomal RNA gene database project: improved data processing and web-based tools , 2012, Nucleic Acids Res..
[34] M. McCarter,et al. HIV-1 Infection of Human Intestinal Lamina Propria CD4+ T Cells In Vitro Is Enhanced by Exposure to Commensal Escherichia coli , 2012, The Journal of Immunology.
[35] M. Zeitz,et al. Rapid mucosal CD4(+) T-cell depletion and enteropathy in simian immunodeficiency virus-infected rhesus macaques. , 1999, Gastroenterology.
[36] R. Kaul,et al. The integrin α4β7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1 , 2009, Proceedings of the National Academy of Sciences.
[37] M. McCarter,et al. Evidence for dendritic cell-dependent CD4(+) T helper-1 type responses to commensal bacteria in normal human intestinal lamina propria. , 2009, Clinical immunology.
[38] Desmond J. Martin,et al. Distribution of the Human Immunodeficiency Virus Coreceptors CXCR4 and CCR5 on Leukocytes of Persons with Human Immunodeficiency Virus Type 1 Infection and Pulmonary Tuberculosis: Implications for Pathogenesis , 2001, Journal of Clinical Immunology.
[39] M. Markowitz,et al. Mechanisms of Gastrointestinal CD4+ T-Cell Depletion during Acuteand Early Human Immunodeficiency Virus Type 1 Infection , 2006, Journal of Virology.
[40] R. Kaul,et al. A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis , 2012, Mucosal Immunology.
[41] Paul M. Ruegger,et al. HIV Infection is associated with compositional and functional shifts in the rectal mucosal microbiota , 2013, Microbiome.
[42] Qingsheng Li,et al. Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells , 2005, Nature.
[43] P. Gaulard,et al. Early initiation of combined antiretroviral therapy preserves immune function in the gut of HIV-infected patients , 2014, Mucosal Immunology.
[44] M. McCarter,et al. Gut Dendritic Cell Activation Links an Altered Colonic Microbiome to Mucosal and Systemic T Cell Activation in Untreated HIV-1 infection , 2015, Mucosal Immunology.
[45] S. Pittaluga,et al. Damaged Intestinal Epithelial Integrity Linked to Microbial Translocation in Pathogenic Simian Immunodeficiency Virus Infections , 2010, PLoS pathogens.
[46] M. Lederman,et al. Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection. , 2009, The Journal of infectious diseases.
[47] F. Belardelli,et al. Human intestinal lamina propria lymphocytes are naturally permissive to HIV‐1 infection , 1999, European journal of immunology.
[48] M. Clerici,et al. Immune activation, apoptosis, and Treg activity are associated with persistently reduced CD4+ T-cell counts during antiretroviral therapy , 2010, AIDS.
[49] M. Lederman,et al. Immunologic failure despite suppressive antiretroviral therapy is related to activation and turnover of memory CD4 cells. , 2011, The Journal of infectious diseases.
[50] M. Markowitz,et al. Lack of Mucosal Immune Reconstitution during Prolonged Treatment of Acute and Early HIV-1 Infection , 2006, PLoS medicine.
[51] B. Palmer,et al. HIV-induced alteration in gut microbiota , 2014, Gut microbes.
[52] J. Lifson,et al. α4+β7hiCD4+ memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection , 2009, Mucosal Immunology.
[53] C. Tincati,et al. Microbial translocation is associated with sustained failure in CD4+ T-cell reconstitution in HIV-infected patients on long-term highly active antiretroviral therapy , 2008, AIDS.
[54] M. McCarter,et al. Microbial exposure alters HIV-1-induced mucosal CD4+ T cell death pathways Ex vivo , 2014, Retrovirology.
[55] K. Mansfield,et al. Identifying the Target Cell in Primary Simian Immunodeficiency Virus (SIV) Infection: Highly Activated Memory CD4+ T Cells Are Rapidly Eliminated in Early SIV Infection In Vivo , 2000, Journal of Virology.
[56] Steven Wolinsky,et al. Microbial Translocation Is Associated with Increased Monocyte Activation and Dementia in AIDS Patients , 2008, PloS one.
[57] A. E. Sousa,et al. Enteric mucosa integrity in the presence of a preserved innate interleukin 22 compartment in HIV type 1-treated individuals. , 2014, The Journal of infectious diseases.
[58] Matthew J. Gebert,et al. Alterations in the gut microbiota associated with HIV-1 infection. , 2013, Cell host & microbe.
[59] S. Dandekar,et al. Gastrointestinal T Lymphocytes Retain High Potential for Cytokine Responses but Have Severe CD4+ T-Cell Depletion at All Stages of Simian Immunodeficiency Virus Infection Compared to Peripheral Lymphocytes , 1998, Journal of Virology.
[60] M. Zeitz,et al. HIV infection and the intestinal mucosal barrier , 2012, Annals of the New York Academy of Sciences.
[61] J. Brenchley,et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection , 2006, Retrovirology.
[62] E. Myers,et al. Basic local alignment search tool. , 1990, Journal of molecular biology.
[63] Z. Klase,et al. Dysbiotic Bacteria Translocate in Progressive SIV Infection , 2014, Mucosal Immunology.
[64] A. d’Arminio Monforte,et al. Evidence for Polymicrobic Flora Translocating in Peripheral Blood of HIV-Infected Patients with Poor Immune Response to Antiretroviral Therapy , 2011, PloS one.