Efficacy and safety of predeposit blood autodonation in 500 cases of myocardial revascularization.

Since 1985 all patients scheduled for coronary artery bypass grafting have been evaluated for admission to a program of predeposited blood autodonation. From a total of 816 consecutive patients, 505 were admitted to the program (group 1). The other 311 (group 2) were excluded on the basis of one or more of the following criteria: 1) emergency surgical indication, 2) hemoglobin less than 12 g/dl, or 3) uncontrolled angina or clinically manifest cardiac failure. Postoperative use of homologous blood products was required by 16% of the group 1 and 44% of the group 2 patients (p less than 0.001). Altogether 597 patients (73%) had no contact with homologous blood products. There was no intergroup difference in the incidence of postoperative complications. Non-A, non-B hepatitis developed in three group 1 and four group 2 patients. Its incidence was 0.9% among all discharged patients and 3.2% of the homologous blood recipients. The findings emphasize the safety and value of the autodonation with predeposit program in significantly reducing the requirement for homologous blood in coronary artery bypass grafting.

[1]  E. Foster,et al.  Predonated autologous blood use in elective cardiac surgery. , 1989, The Annals of thoracic surgery.

[2]  R. Thurer.  Blood conservation in cardiac operations. , 1988, Mayo Clinic proceedings.

[3]  H. Schaff,et al.  Effect of blood conservation efforts in cardiac operations at the Mayo Clinic. , 1988, Mayo Clinic proceedings.

[4]  J. Ward,et al.  Transmission of human immunodeficiency virus (HIV) by blood transfusions screened as negative for HIV antibody. , 1988, The New England journal of medicine.

[5]  J. Bove.  Transfusion-associated hepatitis and AIDS. , 1987, The New England journal of medicine.

[6]  K. Lui,et al.  Estimating the risks of transfusion‐associated acquired immune deficiency syndrome and human immunodeficiency virus infection , 1987, Transfusion.

[7]  W. Daggett,et al.  Transfusion of predonated autologous blood in elective cardiac surgery. , 1987, The Annals of thoracic surgery.

[8]  S. Lemeshow,et al.  Blood conservation for myocardial revascularization. Is it cost effective? , 1987, The Journal of thoracic and cardiovascular surgery.

[9]  J. Avorn,et al.  Blood donation by the elderly. Clinical and policy considerations. , 1987, JAMA.

[10]  H. Jaffe,et al.  Transfusion-associated acquired immunodeficiency syndrome in the United States. , 1985, JAMA.

[11]  Felix Gozo,et al.  "Asanguinous" Open-Heart Surgery , 1985, Indiana medicine : the journal of the Indiana State Medical Association.

[12]  M. Wick,et al.  Non‐A, non‐B hepatitis associated with blood transfusion , 1985, Transfusion.

[13]  Cutler Bs.  Avoidance of homologous transfusion in aortic operations: the role of autotransfusion, hemodilution, and surgical technique. , 1984 .

[14]  D. Goldfinger,et al.  Safety of autologous blood donation prior to elective surgery for a variety of potentially “high‐risk” patients , 1983, Transfusion.

[15]  H. Perkins,et al.  ACQUIRED IMMUNODEFICIENCY IN AN INFANT: POSSIBLE TRANSMISSION BY MEANS OF BLOOD PRODUCTS , 1983, The Lancet.

[16]  A. Alberti,et al.  POST-TRANSFUSION HEPATITIS IN ITALY , 1982, The Lancet.

[17]  E. Klopp,et al.  Autotransfusion: current status. , 1981, Heart & lung : the journal of critical care.

[18]  J. Newell,et al.  Increased cardiac output and oxygen transport after intraoperative isovolemic hemodilution. A study in patients with peripheral vascular disease. , 1980, Archives of surgery.

[19]  R. Malchus,et al.  Hepatitis after Cardiosurgery. Frequency and Causes , 1980, The Thoracic and cardiovascular surgeon.

[20]  W. Bayer,et al.  The use of blood and blood components in 1,769 patients undergoing open-heart surgery. , 1980, The Annals of thoracic surgery.

[21]  F. Loop,et al.  Blood conservation during myocardial revascularization. , 1979, The Annals of thoracic surgery.

[22]  R. Purcell,et al.  The chronic sequelae of non-A, non-B hepatitis. , 1979, Annals of internal medicine.

[23]  J. Matloff,et al.  Autologous Blood Transfusion in Coronary Artery Bypass Surgery , 2003, Transfusion.

[24]  J. Greenberg,et al.  The Use of Autologous Blood in Open‐Heart Surgery , 1974, Transfusion.

[25]  N. Mills,et al.  The Use of Hemodilution and Fresh Autologous Blood in Open‐Heart Surgery , 1974, Anesthesia and analgesia.

[26]  R. Hamstra,et al.  Use of banked autologous blood in elective surgery. , 1971, JAMA.

[27]  J. Anderson,et al.  EMIGRATION TO THE UNITED STATES. , 1965, Lancet.