Modulation of epileptic networks by transient interictal epileptic activity: A dynamic approach to simultaneous EEG-fMRI

Highlights • EEG-fMRI has been instrumental in characterizing brain networks in epilepsy.• Its value is documented in the pre-surgical assessment of drug-resistant epilepsy.• The delineation of brain areas to resect is fundamental for the post-surgical outcome.• Standard EEG-fMRI in epilepsy assesses static functional connectivity of the network.• EEG-fMRI dynamic connectivity identifies transitory features of specific connections.• We integrate dynamic fMRI connectivity and dynamic patterns of simultaneous scalp EEG.• This allows to better characterize the spatiotemporal aspects of epileptic networks.• This may help in more efficiently target the surgical intervention.

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