Generation of myeloid-derived suppressor cells using prostaglandin E2

[1]  James A. Hutchinson,et al.  Alternative approaches to myeloid suppressor cell therapy in transplantation: comparing regulatory macrophages to tolerogenic DCs and MDSCs , 2012, Transplantation research.

[2]  S. Gregori,et al.  Human tolerogenic DC-10: perspectives for clinical applications , 2012, Transplantation research.

[3]  C. Macedo,et al.  Immunoregulatory properties of rapamycin-conditioned monocyte-derived dendritic cells and their role in transplantation , 2012, Transplantation research.

[4]  P. Dahm,et al.  Circulating and tumor‐infiltrating myeloid cell subsets in patients with bladder cancer , 2012, International journal of cancer.

[5]  P. Kalinski.  Regulation of Immune Responses by Prostaglandin E2 , 2012, The Journal of Immunology.

[6]  K. Odunsi,et al.  PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment. , 2011, Cancer research.

[7]  R. Edwards,et al.  Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells. , 2011, Blood.

[8]  S. H. van der Burg,et al.  M2 Macrophages Induced by Prostaglandin E2 and IL-6 from Cervical Carcinoma Are Switched to Activated M1 Macrophages by CD4+ Th1 Cells , 2011, The Journal of Immunology.

[9]  J. G. Cripps,et al.  MDSC in autoimmunity. , 2011, International immunopharmacology.

[10]  B. Rini,et al.  Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma. , 2011, Neuro-oncology.

[11]  G. Lesinski,et al.  Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4+ T cells from patients with GI malignancy , 2011, Cancer Immunology, Immunotherapy.

[12]  D. Munn,et al.  Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13. , 2010, Blood.

[13]  A. Le Moine,et al.  Myeloid-derived suppressor cells in transplantation , 2010, Current opinion in organ transplantation.

[14]  C. Divino,et al.  Myeloid-Derived Suppressor Cells Prevent Type 1 Diabetes in Murine Models , 2010, The Journal of Immunology.

[15]  J. Ochando,et al.  Myeloid-derived suppressor cells: natural regulators for transplant tolerance. , 2010, Human immunology.

[16]  P. Serafini.  Editorial: PGE2‐producing MDSC: a role in tumor progression? , 2010, Journal of leukocyte biology.

[17]  J. Vieweg,et al.  Pivotal Advance: Tumor‐mediated induction of myeloid‐derived suppressor cells and M2‐polarized macrophages by altering intracellular PGE2 catabolism in myeloid cells , 2010, Journal of leukocyte biology.

[18]  Y. Shoenfeld,et al.  Tolerogenic dendritic cells in autoimmune diseases: crucial players in induction and prevention of autoimmunity. , 2010, Autoimmunity reviews.

[19]  Pei Su,et al.  High‐Efficiency Induction of Neural Conversion in Human ESCs and Human Induced Pluripotent Stem Cells with a Single Chemical Inhibitor of Transforming Growth Factor Beta Superfamily Receptors , 2010, Stem cells.

[20]  A. Epstein,et al.  Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells , 2010, The Journal of Immunology.

[21]  Bali Pulendran,et al.  Programming dendritic cells to induce TH2 and tolerogenic responses , 2010, Nature Immunology.

[22]  S. Wenzel,et al.  TLR4/MyD88-Induced CD11b+Gr-1intF4/80+ Non-Migratory Myeloid Cells Suppress Th2 Effector Function in the Lung , 2010, Mucosal Immunology.

[23]  H. Ueno,et al.  Dendritic Cells: Are They Clinically Relevant? , 2010, Cancer journal.

[24]  F. Ginhoux,et al.  Monocytic suppressive cells mediate cardiovascular transplantation tolerance in mice. , 2010, The Journal of clinical investigation.

[25]  S. Bicciato,et al.  Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor. , 2010, Immunity.

[26]  A. Dietz,et al.  Immunosuppressive CD14+HLA‐DRlow/− monocytes in prostate cancer , 2010, The Prostate.

[27]  C. Divino,et al.  Development and Function of Myeloid‐Derived Suppressor Cells Generated From Mouse Embryonic and Hematopoietic Stem Cells , 2010, Stem cells.

[28]  E. Traggiai,et al.  Hierarchy of immunosuppressive strength among myeloid‐derived suppressor cell subsets is determined by GM‐CSF , 2009, European journal of immunology.

[29]  M. Manns,et al.  Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor , 2009, Hepatology.

[30]  M. Goldman,et al.  Endotoxin‐Induced Myeloid‐Derived Suppressor Cells Inhibit Alloimmune Responses via Heme Oxygenase‐1 , 2009, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[31]  T. Padhya,et al.  Mechanism Regulating Reactive Oxygen Species in Tumor-Induced Myeloid-Derived Suppressor Cells1 , 2009, The Journal of Immunology.

[32]  Srinivas Nagaraj,et al.  Myeloid-derived suppressor cells as regulators of the immune system , 2009, Nature Reviews Immunology.

[33]  Xuetao Cao,et al.  Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF-β11 , 2009, The Journal of Immunology.

[34]  Yuan Zhang,et al.  B7-H1 on myeloid-derived suppressor cells in immune suppression by a mouse model of ovarian cancer. , 2008, Clinical immunology.

[35]  Wei Zhang,et al.  Human Inhibitory Receptor Immunoglobulin-Like Transcript 2 Amplifies CD11b+Gr1+ Myeloid-Derived Suppressor Cells That Promote Long-Term Survival of Allografts , 2008, Transplantation.

[36]  M. Manns,et al.  Myeloid-derived suppressor cells in inflammatory bowel disease: a new immunoregulatory pathway. , 2008, Gastroenterology.

[37]  M. Manns,et al.  A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells. , 2008, Gastroenterology.

[38]  M. Zöller,et al.  The Importance of Myeloid-Derived Suppressor Cells in the Regulation of Autoimmune Effector Cells by a Chronic Contact Eczema1 , 2007, The Journal of Immunology.

[39]  V. Kuchroo,et al.  CD11b+Ly-6Chi Suppressive Monocytes in Experimental Autoimmune Encephalomyelitis1 , 2007, The Journal of Immunology.

[40]  L. Mariani,et al.  Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[41]  L. Moldawer,et al.  MyD88-dependent expansion of an immature GR-1+CD11b+ population induces T cell suppression and Th2 polarization in sepsis , 2007, The Journal of experimental medicine.

[42]  P. Sinha,et al.  Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells. , 2007, Cancer research.

[43]  S. Narumiya,et al.  Prostaglandin E Receptors* , 2007, Journal of Biological Chemistry.

[44]  G. Rabinovich,et al.  Immunosuppressive strategies that are mediated by tumor cells. , 2007, Annual review of immunology.

[45]  P. Rodriguez,et al.  Arginase, Prostaglandins, and Myeloid-Derived Suppressor Cells in Renal Cell Carcinoma , 2007, Clinical Cancer Research.

[46]  A. Villa,et al.  Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth factor-beta-mediated suppressive activity on T lymphocytes. , 2006, Cancer research.

[47]  A. Gruber,et al.  Autoimmune-mediated intestinal inflammation-impact and regulation of antigen-specific CD8+ T cells. , 2006, Gastroenterology.

[48]  D. Gabrilovich,et al.  Tumor Associated CD8+ T-Cell Tolerance Induced by Bone Marrow Derived Immature Myeloid Cells , 2005 .

[49]  S. Dubinett,et al.  Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma , 2005, The Journal of experimental medicine.

[50]  V. Bronte,et al.  Regulation of immune responses by L-arginine metabolism , 2005, Nature Reviews Immunology.

[51]  G. Hill,et al.  Cytokine Expanded Myeloid Precursors Function as Regulatory Antigen-Presenting Cells and Promote Tolerance through IL-10-Producing Regulatory T Cells1 , 2005, The Journal of Immunology.

[52]  D. Gabrilovich.  Mechanisms and functional significance of tumour-induced dendritic-cell defects , 2004, Nature Reviews Immunology.

[53]  D. Munn,et al.  Ido expression by dendritic cells: tolerance and tryptophan catabolism , 2004, Nature Reviews Immunology.

[54]  T. Curiel,et al.  Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity , 2003, Nature Medicine.

[55]  Jeonghee Cho,et al.  Induction of COX‐2 by LPS in macrophages is regulated by Tpl2‐dependent CREB activation signals , 2002, The EMBO journal.

[56]  V. Bronte,et al.  Tumor-induced immune dysfunctions caused by myeloid suppressor cells. , 2001, Journal of immunotherapy.

[57]  J. Banchereau,et al.  Sensing Pathogens and Tuning Immune Responses , 2001, Science.

[58]  J. Banchereau,et al.  IL-6 switches the differentiation of monocytes from dendritic cells to macrophages , 2000, Nature Immunology.

[59]  K. Ozato,et al.  Interferon Regulatory Factor (Irf)-1 and Irf-2 Regulate Interferon γ–Dependent Cyclooxygenase 2 Expression , 2000, The Journal of experimental medicine.

[60]  Milton W. Taylor,et al.  Indoleamine 2,3-Dioxygenase Production by Human Dendritic Cells Results in the Inhibition of T Cell Proliferation , 2000, The Journal of Immunology.

[61]  Li Zhu,et al.  Specific Inhibition of Cyclooxygenase 2 Restores Antitumor Reactivity by Altering the Balance of IL-10 and IL-12 Synthesis1 , 2000, The Journal of Immunology.

[62]  J. Blay,et al.  Inhibition of the differentiation of dendritic cells from CD34(+) progenitors by tumor cells: role of interleukin-6 and macrophage colony-stimulating factor. , 1998, Blood.

[63]  D. Carbone,et al.  Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo. , 1998, Blood.

[64]  Li Zhu,et al.  Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production. , 1998, Cancer research.

[65]  P. Kalinski,et al.  IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells. , 1997, Journal of immunology.

[66]  D. Gabrilovich,et al.  Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function. , 2011, Trends in immunology.

[67]  V. Kuchroo,et al.  CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis. , 2007, Journal of immunology.