Staphylococcus aureus requires less virulence to establish an infection in diabetic hosts.

[1]  M. Spraul,et al.  Diabetic Foot Syndrome. , 2020, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

[2]  T. Foster,et al.  The remarkably multifunctional fibronectin binding proteins of Staphylococcus aureus , 2016, European Journal of Clinical Microbiology and Infectious Diseases.

[3]  A. Mellmann,et al.  Real-Time Genome Sequencing of Resistant Bacteria Provides Precision Infection Control in an Institutional Setting , 2016, Journal of Clinical Microbiology.

[4]  C. Dunyach-Rémy,et al.  Staphylococcus aureus Toxins and Diabetic Foot Ulcers: Role in Pathogenesis and Interest in Diagnosis , 2016, Toxins.

[5]  B. Furman,et al.  Streptozotocin‐Induced Diabetic Models in Mice and Rats , 2015, Current protocols in pharmacology.

[6]  M. Fraunholz,et al.  Sigma Factor SigB Is Crucial to Mediate Staphylococcus aureus Adaptation during Chronic Infections , 2015, PLoS pathogens.

[7]  V. Fowler,et al.  Amino acid alterations in fibronectin binding protein A (FnBPA) and bacterial genotype are associated with cardiac device related infection in Staphylococcus aureus bacteraemia. , 2015, The Journal of infection.

[8]  Benjamin A Lipsky,et al.  Ceftaroline fosamil for treatment of diabetic foot infections: the CAPTURE study experience , 2015, Diabetes/metabolism research and reviews.

[9]  G. Peters,et al.  Staphylococcus aureus isolates from chronic osteomyelitis are characterized by high host cell invasion and intracellular adaptation, but still induce inflammation. , 2014, International journal of medical microbiology : IJMM.

[10]  Benjamin A Lipsky,et al.  Do Diabetic Foot Infections With Methicillin-Resistant Staphylococcus aureus Differ From Those With Other Pathogens? , 2014, The international journal of lower extremity wounds.

[11]  S. Fauziyah,et al.  Antibiotic therapy for diabetic foot infections in a tertiary care hospital in Jakarta, Indonesia. , 2014, Diabetes & metabolic syndrome.

[12]  Suleyman Yazici,et al.  The relationship between complete blood count parameters and Fontaine’s Stages in patients with peripheral arterial disease , 2014, Vascular.

[13]  Benjamin A Lipsky,et al.  Diabetic Foot Ulcer Microbiome: One Small Step for Molecular Microbiology . . . One Giant Leap for Understanding Diabetic Foot Ulcers? , 2013, Diabetes.

[14]  R. Ridley,et al.  Differential adhesion and invasion by Staphylococcus aureus of epithelial cells derived from different anatomical sites. , 2012, Journal of medical microbiology.

[15]  M. Fraunholz,et al.  Intracellular staphylococcus aureus: Live-in and let die , 2012, Front. Cell. Inf. Microbio..

[16]  Sunny Park,et al.  Reduced Neutrophil Apoptosis in Diabetic Mice during Staphylococcal Infection Leads to Prolonged Tnfα Production and Reduced Neutrophil Clearance , 2011, PloS one.

[17]  R. Proctor,et al.  Staphylococcus aureus phenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infection , 2011, EMBO molecular medicine.

[18]  Benjamin A Lipsky,et al.  Treating Osteomyelitis: Antibiotics and Surgery , 2011, Plastic and reconstructive surgery.

[19]  D. Viemann,et al.  Staphylococcal strains vary greatly in their ability to induce an inflammatory response in endothelial cells. , 2010, The Journal of infectious diseases.

[20]  F. Lowy Staphylococcus aureus infections. , 2009, The New England journal of medicine.

[21]  George Y. Liu Molecular Pathogenesis of Staphylococcus aureus Infection , 2009, Pediatric Research.

[22]  J. S. van de Gevel,et al.  Contribution of (sub)domains of Staphylococcus aureus fibronectin-binding protein to the proinflammatory and procoagulant response of human vascular endothelial cells , 2009, Thrombosis and Haemostasis.

[23]  Sunny Park,et al.  Defects in Innate Immunity Predispose C57BL/6J-Leprdb/Leprdb Mice to Infection by Staphylococcus aureus , 2008, Infection and Immunity.

[24]  S. Lenzen,et al.  The mechanisms of alloxan- and streptozotocin-induced diabetes , 2008, Diabetologia.

[25]  A. Kennedy,et al.  Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA , 2007, Nature Medicine.

[26]  Jean C. Lee,et al.  The pathogenesis of Staphylococcus aureus infection in the diabetic NOD mouse. , 2005, Diabetes.

[27]  U. Fischer,et al.  Multiple virulence factors are required for Staphylococcus aureus‐induced apoptosis in endothelial cells , 2005, Cellular microbiology.

[28]  C. Wolz,et al.  sae is essential for expression of the staphylococcal adhesins Eap and Emp. , 2005, Microbiology.

[29]  G. Peters,et al.  Truncation of Fibronectin-Binding Proteins in Staphylococcus aureus Strain Newman Leads to Deficient Adherence and Host Cell Invasion Due to Loss of the Cell Wall Anchor Function , 2004, Infection and Immunity.

[30]  F. Waldvogel,et al.  Osteomyelitis , 2004, The Lancet.

[31]  G. Peters,et al.  Reduced adherence and host cell invasion by methicillin-resistant Staphylococcus aureus expressing the surface protein Pls. , 2004, The Journal of infectious diseases.

[32]  K. Schulze-Osthoff,et al.  Staphylococcus aureusα‐toxin induces apoptosis in peripheral blood mononuclear cells: role of endogenous tumour necrosis factor‐α and the mitochondrial death pathway , 2003, Cellular microbiology.

[33]  B. Menzies,et al.  The role of fibronectin binding proteins in the pathogenesis of Staphylococcus aureus infections , 2003, Current opinion in infectious diseases.

[34]  M. Clare-Salzer,et al.  Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[35]  Chyung-Ru Wang,et al.  Cd1-Restricted Nk T Cells Protect Nonobese Diabetic Mice from Developing Diabetes , 2001, The Journal of experimental medicine.

[36]  M. Pfaffl,et al.  A new mathematical model for relative quantification in real-time RT-PCR. , 2001, Nucleic acids research.

[37]  J. Bluestone,et al.  B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. , 2000, Immunity.

[38]  Bhanu Sinha,et al.  Fibronectin‐binding protein acts as Staphylococcus aureus invasin via fibronectin bridging to integrin α5β1 , 1999, Cellular microbiology.

[39]  M. Smeltzer,et al.  Mechanisms of Staphylococcus aureus invasion of cultured osteoblasts. , 1999, Microbial pathogenesis.

[40]  T. Foster,et al.  Surface protein adhesins of Staphylococcus aureus. , 1998, Trends in microbiology.

[41]  H. Gaskins,et al.  Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice. , 1993, Journal of immunology.

[42]  I Nicoletti,et al.  A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. , 1991, Journal of immunological methods.

[43]  J. Bach,et al.  Anti‐suppressor effect of cyclophosphamide on the development of spontaneous diabetes in nod mice , 1988, European journal of immunology.

[44]  J. Satoh,et al.  Immunologic Aspects of the Nonobese Diabetic (NOD) Mouse: Abnormalities of Cellular Immunity , 1983, Diabetes.

[45]  D. Armstrong,et al.  2012 infectious diseases society of america clinical practice guideline for the diagnosis and treatment of diabetic foot infections. , 2013, Journal of the American Podiatric Medical Association.

[46]  J. Roth,et al.  Subcutaneous infection with S. aureus in mice reveals association of resistance with influx of neutrophils and Th2 response. , 2011, The Journal of investigative dermatology.

[47]  M. Bischoff,et al.  Role of (cid:2) B in the Expression of Staphylococcus aureus Cell Wall Adhesins ClfA and FnbA and Contribution to Infectivity in a Rat Model of Experimental Endocarditis , 2005 .

[48]  Mark S. Anderson,et al.  The NOD mouse: a model of immune dysregulation. , 2005, Annual review of immunology.

[49]  J. Bluestone,et al.  Impairment of NK cell function by NKG2D modulation in NOD mice. , 2003, Immunity.

[50]  S Bhakdi,et al.  Alpha-toxin of Staphylococcus aureus. , 1991, Microbiological reviews.

[51]  F. Cerra,et al.  Stimulation of repair in chronic, nonhealing, cutaneous ulcers using platelet-derived wound healing formula. , 1990, Surgery, gynecology & obstetrics.