Bioimpedance: A Review for Food Processing

Electrical measurement is a simple innocuous tool for material characterization. Unlike for instance milk or dairy products, the majority of naturally grown food is composed of cells. The cells of meat or vegetables are surrounded by an insulating membrane, while the cytosol and the extracellular fluids are electrolytes. Despite the high permittivity of water, electrolytes behave like ohmic resistors up to hundreds of MHz. In contrast, membranes form capacitive elements due to their high resistance. The typical time constant for charging cell membranes is of the order of a microsecond. Thus, cells influence the impedance in a frequency range up to several MHz. At higher frequencies, the cytosolic content, i.e., macromolecules, gives rise to characteristic relaxation processes. Using the impedance in the microwave range where water dipoles show a distinct dispersion, humidity of dried matter can be addressed. Moreover, with sensitive measurement setup and proper models, one can determine the dry content in mashes and slurries as well. Several quality standards correlate well with the permeability of the membranes or the total water content. Because of the comparatively simple measurement of the electrical impedance together with advanced mathematical modeling, it is often a good approach in quality assessment of agricultural products. The change in conductivity of a culture medium contains information about the metabolism of incubated cells. Using specific culture media and time-lapse conductivity monitoring allows a high sensitivity and selectivity in microbial detection. Because the electrical impedance is very sensitive to the permeability of cell membranes, it is a great choice for the assessment of changes due to high voltage application. Today, many attempts to use impedance measurement in food technology show fast success in research but fail in practice. The reason is often an overestimation especially of the selectivity while underestimating the uncertainties in a harsh environment of a food-processing plant. Established, however, is the use of robust process measurement systems and the limitation of impedance measurement to applications with highly significant outcome or as supplemental measurement in a multiparameter approach. This review introduces the basics of bioimpedance measurement, points to sources of uncertainty, and presents successful applications in food industry.

[1]  J. Lyng,et al.  Dielectric and thermophysical properties of different beef meat blends over a temperature range of -18 to +10°C. , 2008, Meat science.

[2]  E. Gersing,et al.  Evaluation of Fast Time-domain Based Impedance Measurements on Biological Tissue - Beurteilung schneller Impedanzmessungen im Zeitbereich an biologischen Geweben , 2000, Biomedizinische Technik. Biomedical engineering.

[3]  Hanne Christine Bertram,et al.  Relationship between meat structure, water mobility, and distribution: a low-field nuclear magnetic resonance study. , 2002, Journal of agricultural and food chemistry.

[4]  Stephan Noack,et al.  New type of dry substances content meter using microwaves for application in biogas plants , 2005, Analytical and bioanalytical chemistry.

[5]  Joseph G. Hoffman,et al.  Physical Techniques in Biological Research , 1963 .

[6]  R Bragós,et al.  A wide-band AC-coupled current source for electrical impedance tomography. , 1994, Physiological measurement.

[7]  Werner Ebeling,et al.  Theorie der Elektrolyte , 1971 .

[8]  JOHN W. Moore Membranes, ions, and impulses , 1976 .

[9]  Prediction of fat-free mass of pigs from 50 to 130 kilograms live weight. , 1999, Journal of animal science.

[10]  M. Chanet,et al.  Electric impedance spectrometry for the control of manufacturing process of comminuted meat products , 1999 .

[11]  H. Fricke,et al.  THE ELECTRIC RESISTANCE AND CAPACITY OF BLOOD FOR FREQUENCIES BETWEEN 800 AND 4½ MILLION CYCLES , 1925, The Journal of general physiology.

[12]  DESIGN OF A SYSTEM FOR CONTACT-FREE MEASUREMENT OF THE CONDUCTIVITY OF BIOLOGICAL TISSUE , 2002, Biomedizinische Technik. Biomedical engineering.

[13]  S. Trabelsi,et al.  Dielectric properties of uncooked chicken breast muscles from ten to one thousand eight hundred megahertz. , 2007, Poultry science.

[14]  M. Kent,et al.  Composition of foods including added water using microwave dielectric spectra , 2001 .

[15]  E. Neumann,et al.  Electroporation and Electrofusion in Cell Biology , 1989, Springer US.

[16]  J. Weaver,et al.  Electroporation: A general phenomenon for manipulating cells and tissues , 1993, Journal of cellular biochemistry.

[17]  Reinhard Knöchel,et al.  Resonant microwave sensors for instantaneous determination of moisture in foodstuffs , 2001 .

[18]  C Gabriel,et al.  The dielectric properties of biological tissues: I. Literature survey. , 1996, Physics in medicine and biology.

[19]  Dietrich Knorr,et al.  Electrophysiological Model of Intact and Processed Plant Tissues: Cell Disintegration Criteria , 1999, Biotechnology progress.

[20]  R. Cole,et al.  Evaluation of dielectric behavior by time domain spectroscopy. 3. Precision difference methods , 1980 .

[21]  Jean-Louis Damez,et al.  Beef meat electrical impedance spectroscopy and anisotropy sensing for non-invasive early assessment of meat ageing , 2008 .

[22]  S. Nelson Dielectric properties of agricultural products-measurements and applications , 1991 .

[23]  L. A. Geddes,et al.  The polarization impedance of common electrode metals operated at low current density , 2006, Annals of Biomedical Engineering.

[24]  J. D. Bourland,et al.  Tetrapolar electrode system for measuring physiological events by impedance , 2006, Medical and Biological Engineering and Computing.

[25]  M. Marchello,et al.  Bioelectrical impedance can predict skeletal muscle and fat-free skeletal muscle of beef cows and their carcasses. , 1994, Journal of animal science.

[26]  L. Ward,et al.  Prediction of the chemical composition of lamb carcasses from multi-frequency impedance data , 1998, British Journal of Nutrition.

[27]  G. Chryssikos,et al.  Time domain reflection methods for dielectric measurements to 10 GHz , 1989 .

[28]  J. Oehlenschläger,et al.  A new multivariate approach to the problem of fish quality estimation , 2004 .

[29]  F Pliquett,et al.  P(y)-a parameter for meat quality. , 2003, Meat science.

[30]  Eugène Vorobiev,et al.  Estimation of characteristic damage time of food materials in pulsed-electric fields , 2002 .

[31]  M. Marchello,et al.  Bioelectrical impedance: fat content of beef and pork from different size grinds. , 1999, Journal of animal science.

[32]  P Riu,et al.  Evaluation of the electrical impedance spectroscopy (EIS) equipment for ham meat quality selection. , 2001, Meat science.

[33]  F. Vacher,et al.  Eddy current nondestructive testing with giant magneto-impedance sensor , 2007 .

[34]  R. Cole,et al.  Time domain reflectometry. , 1977, Annual review of physical chemistry.

[35]  Rudolf Zetik,et al.  Liquid and moisture sensing by ultra-wideband pseudo-noise sequence signals , 2007 .

[36]  D. Kell,et al.  The passive electrical properties of biological systems: their significance in physiology, biophysics and biotechnology. , 1987, Physics in medicine and biology.

[37]  K. Schoenbach,et al.  Changes in electrical impedance of biological matter due to the application of ultrashort high voltage pulses , 2009, IEEE Transactions on Dielectrics and Electrical Insulation.

[38]  Stuart O. Nelson,et al.  Electrical Properties of Agricultural Products-A Critical Review , 1973 .

[39]  Frank Daschner,et al.  Time domain reflectometry as a tool for the estimation of quality in foods , 2004 .

[40]  Sverre Grimnes,et al.  Bioimpedance and Bioelectricity Basics , 2000 .

[41]  R. Bragós,et al.  Biomass Monitoring Using Impedance Spectroscopy a , 1999, Annals of the New York Academy of Sciences.

[42]  K. Foster,et al.  Dielectric properties of tissues and biological materials: a critical review. , 1989, Critical reviews in biomedical engineering.

[43]  M. Kent,et al.  Determination of prior treatment of fish and fish products using microwave dielectric spectra , 2000 .

[44]  S. O. Nelson,et al.  FREQUENCY AND TEMPERATURE DEPENDENCE OF THE DIELECTRIC PROPERTIES OF FOOD MATERIALS , 2002 .

[45]  M. Kent,et al.  Determination of added water in pork products using microwave dielectric spectroscopy , 2002 .

[46]  Yuri Feldman,et al.  Time domain dielectric spectroscopy study of biological systems , 2003 .

[47]  Douglas B. Kell,et al.  Dielectric permittivity of microbial suspensions at radio frequencies: a novel method for the real-time estimation of microbial biomass , 1987 .

[48]  Uwe Pliquett,et al.  Nonlinear current-voltage relationship of the plasma membrane of single CHO cells. , 2007, Bioelectrochemistry.

[49]  Leslie A. Geddes,et al.  Who introduced the tetrapolar method for measuring resistance and impedance , 1996 .

[50]  H. Schwan Electrical properties of tissue and cell suspensions. , 1957, Advances in biological and medical physics.

[51]  Juming Tang,et al.  Dielectric properties of foods relevant to RF and microwave pasteurization and sterilization , 2003 .

[52]  R. W. Lau,et al.  The dielectric properties of biological tissues: II. Measurements in the frequency range 10 Hz to 20 GHz. , 1996, Physics in medicine and biology.

[53]  Taner Baysal,et al.  Dielectrical Properties of Food Materials—1: Factors Affecting and Industrial Uses , 2004, Critical reviews in food science and nutrition.

[54]  S. Bone,et al.  Time domain reflectrometry: the difference method applied to conductive aqueous solutions. , 1988, Biochimica et biophysica acta.

[55]  Herman P. Schwan,et al.  CHAPTER 6 – DETERMINATION OF BIOLOGICAL IMPEDANCES1 , 1963 .

[56]  Douglas J. Reinemann,et al.  Online Milk Sensing Issues for Automatic Milking , 2004 .

[57]  Christopher L. Davey,et al.  Introduction to the dielectric estimation of cellular biomass in real time, with special emphasis on measurements at high volume fractions , 1993 .

[58]  R. Firstenberg-Eden,et al.  Electrochemical changes in media due to microbial , 1984 .

[59]  M Min,et al.  Broadband excitation for short-time impedance spectroscopy , 2008, Physiological measurement.

[60]  R. W. Lau,et al.  The dielectric properties of biological tissues: III. Parametric models for the dielectric spectrum of tissues. , 1996, Physics in medicine and biology.

[61]  U. Pliquett,et al.  Prediction of intramuscular fat by impedance spectroscopy. , 2006, Meat science.

[62]  Rudolf Höber,et al.  Eine Methode, die elektrische Leitfähigkeit im Innern von Zellen zu messen , 1910, Pflüger's Archiv für die gesamte Physiologie des Menschen und der Tiere.