Introducing estimated glomerular filtration rate (eGFR) into clinical practice in the UK: implications for the use of metformin

Aims  The reporting of estimated glomerular filtration rate (eGFR) will identify people with diabetes who have previously undiagnosed renal impairment. Our current guideline recommends discontinuation of metformin when serum creatinine > 150 µmol/l. We examined the implications of replacing this with a criterion based on eGFR.