The mechanism of excitation by acetylcholine in the cerebral cortex

1. The muscarinic depolarizing action of ACh on cortical neurones is associated with an increase in membrane resistance (mean ΔV/ΔR = 3·16 mV/MΩ).

[1]  H. Jasper,et al.  INTRACELLULAR OSCILLATORY RHYTHMS IN PYRAMIDAL TRACT NEURONES IN THE CAT. , 1965, Electroencephalography and clinical neurophysiology.

[2]  M. Spiegel-Adolf,et al.  Cerebrospinal fluid. , 1965, Progress in neurology and psychiatry.

[3]  K. Krnjević,et al.  Acetylcholine‐sensitive cells in the cerebral cortex , 1963, The Journal of physiology.

[4]  B. Libet,et al.  Actions of noradrenaline and acetylcholine on sympathetic ganglion cells , 1970, The Journal of physiology.

[5]  K. Krnjević,et al.  Actions of dinitrophenol and some other metabolic inhibitors on cortical neurones , 1971, The Journal of physiology.

[6]  K. Krnjević,et al.  Iontophoretic studies of neurones in the mammalian cerebral cortex , 1963, The Journal of physiology.

[7]  R. Gerard Biological roots of psychiatry. , 1955, Science.

[8]  R. H. Adrian,et al.  The potassium and chloride conductance of frog muscle membrane , 1962, The Journal of physiology.

[9]  R. B. Wuerker,et al.  Membrane impedance changes during synaptic transmission in cat spinal motoneurons. , 1967, Journal of neurophysiology.

[10]  D. R. Curtis,et al.  Pharmacological studies on feline Betz cells , 1966, The Journal of physiology.

[11]  R. Spehlmann Acetylcholine and prostigmine electrophoresis at visual cortex neurons. , 1963, Journal of neurophysiology.

[12]  E. Bulbring Changes in configuration of spontaneously discharged spike potentials from smooth muscle of the guinea-pig's taenia coli; the effect of electrotonic currents and of adrenaline, acetylcholine and histamine. , 1957, The Journal of physiology.

[13]  W W Alberts,et al.  Responses of human somatosensory cortex to stimuli below threshold for conscious sensation. , 1967, Science.

[14]  S. W. Kuffler,et al.  The physiology of neuroglial cells. , 1966, Ergebnisse der Physiologie, biologischen Chemie und experimentellen Pharmakologie.

[15]  M. Randić,et al.  ACETYLCHOLINE DEPRESSION OF CORTICAL NEURONS. , 1964, Experimental neurology.

[16]  K. Krnjević,et al.  A histochemical study of cholinergic fibres in the cerebral cortex. , 1965, Journal of anatomy.

[17]  B. Libet,et al.  Generation of slow postsynaptic potentials without increases in ionic conductance. , 1968, Proceedings of the National Academy of Sciences of the United States of America.

[18]  M. Dennis,et al.  Some physiological properties of identified mammalian neuroglial cells , 1969, The Journal of physiology.

[19]  C. Li Cortical intracellular synaptic potentials. , 1961, Journal of cellular and comparative physiology.

[20]  M. Santini,et al.  Hyperpolarizing increase in membrane conductance in hippocampal neurons. , 1968, Brain research.

[21]  K. Krnjević,et al.  Pharmacology of cortical inhibition , 1966, The Journal of physiology.

[22]  A. Ames,et al.  Relation of potassium concentration in choroidplexus fluid to that in plasma. , 1965, The Journal of physiology.

[23]  G. Koelle The histochemical localization of cholinesterases in the central nervous system of the rat , 1954, The Journal of comparative neurology.

[24]  P. G. Nelson,et al.  Anomalous rectification in cat spinal motoneurons and effect of polarizing currents on excitatory postsynaptic potential. , 1967, Journal of neurophysiology.

[25]  K. Takahashi,et al.  Slow and fast groups of pyramidal tract cells and their respective membrane properties. , 1965, Journal of neurophysiology.

[26]  A. Hodgkin,et al.  A quantitative description of membrane current and its application to conduction and excitation in nerve , 1952, The Journal of physiology.

[27]  K. Krnjević,et al.  Unexpected Features of the Action of Dinitrophenol on Cortical Neurones , 1970, Nature.

[28]  A. Hodgkin,et al.  The influence of potassium and chloride ions on the membrane potential of single muscle fibres , 1959, The Journal of physiology.

[29]  D A Pollen,et al.  Electrical constants of neurons in the motor cortex of the cat. , 1966, Journal of neurophysiology.

[30]  D. Jenkinson,et al.  The effect of carbachol on the permeability of depolarized smooth muscle to inorganic ions , 1961, The Journal of physiology.

[31]  W. Holland,et al.  Studies on the permeability of erythrocytes. III. The effect of physostigmine and acetylcholine on the permeability of dog, cat and rabbit erythrocytes to sodium and potassium. , 1950, The American journal of physiology.

[32]  C. G. Phillips,et al.  Actions of antidromic pyramidal volleys on single Betz cells in the cat. , 1959, Quarterly journal of experimental physiology and cognate medical sciences.

[33]  K. Krnjević Central cholinergic pathways. , 1969, Federation proceedings.

[34]  B. Libet,et al.  Cortical Activation in Conscious and Unconscious Experience , 2015, Perspectives in biology and medicine.

[35]  K. Krnjević,et al.  Effects of Ba2+ and tetraethylammonium on cortical neurones , 1971, The Journal of physiology.

[36]  D. Jenkinson,et al.  The calcium dependence of tension development in depolarized smooth muscle , 1961, The Journal of physiology.

[37]  K. Krnjević,et al.  Pharmacological properties of acetylcholine‐sensitive cells in the cerebral cortex , 1963, The Journal of physiology.

[38]  D. B. Tower,et al.  FLUID COMPARTMENTATION AND ELECTROLYTES OF CAT CEREBRAL CORTEX IN VITRO–II SODIUM, POTASSIUM AND CHLORIDE OF MATURE CEREBRAL CORTEX , 1966, Journal of neurochemistry.

[39]  F. F. Weight,et al.  Slow Synaptic Excitation in Sympathetic Ganglion Cells: Evidence for Synaptic Inactivation of Potassium Conductance , 1970, Science.

[40]  J. Phillis,et al.  Pharmacological studies on a cholinergic inhibition in the cerebral cortex. , 1968, Brain research.