Pumping potential of a two-layer left-ventricle-like flexible-matrix-composite structure

The pumping potential, defined as the amount of relative volume reduction engendered by an applied load (relative input stroke), is an important criterion for flexible-body pumps. It is introduced as a measure of the volumetric efficiency of pumping. The PP of many flexible-matrix-composite (FMC) structures has been considered in the literature. Most recently, the PP of a single-layer left-ventricle-like FMC structure, based on the helical ventricular myocardial band hypothesis, has been investigated. A PP of 1.67–1.9 has been achieved. Though reasonably high, it is much smaller than that of the actual left ventricle of the heart (3.33–4.0). In here this work is extended to a two-layer left-ventricle-like FMC structure, which adopts a more accurate fiber orientation. The PP of the two-layer left-ventricle-like FMC structure is determined experimentally and analytically. A FMC flat band is created then twisted and looped to form the flexible-body structure. The analytical investigation using the ANSYS software engenders a PP of 2.5, and the experimental one using a PU/SMA (shape memory alloy) FMC renders a PP of 2.85. These higher values of PP indicate that accurate fiber-orientation in heart-mimicking flexible-structural pumps is very important.

[1]  Enric Martí,et al.  MIOCARDIA: integrating cardiac function and muscular architecture for a better diagnosis , 2011, ISABEL '11.

[2]  Gerald D Buckberg,et al.  Basic science review: the helix and the heart. , 2002, The Journal of thoracic and cardiovascular surgery.

[3]  G. Buckberg,et al.  Spatial orientation of the ventricular muscle band: physiologic contribution and surgical implications. , 2001, The Journal of thoracic and cardiovascular surgery.

[4]  E. Sonnenblick,et al.  Structural conditions in the hypertrophied and failing heart. , 1973, The American journal of cardiology.

[5]  F. P. Mall,et al.  On the muscular architecture of the ventricles of the human heart , 1911 .

[6]  A. McCulloch,et al.  Passive material properties of intact ventricular myocardium determined from a cylindrical model. , 1991, Journal of biomechanical engineering.

[7]  M. Gharib,et al.  Computational models of heart pumping efficiencies based on contraction waves in spiral elastic bands. , 2009, Journal of theoretical biology.

[8]  P. Hunter,et al.  Mathematical model of geometry and fibrous structure of the heart. , 1991, The American journal of physiology.

[9]  Michael Philen,et al.  Variable Stiffness Structures Utilizing Fluidic Flexible Matrix Composites , 2009 .

[10]  A. McCulloch,et al.  Finite element stress analysis of left ventricular mechanics in the beating dog heart. , 1995, Journal of biomechanics.

[11]  I. LeGrice,et al.  Shear properties of passive ventricular myocardium. , 2002, American journal of physiology. Heart and circulatory physiology.

[12]  R J Zdrahala,et al.  Biomedical Applications of Polyurethanes: A Review of Past Promises, Present Realities, and a Vibrant Future , 1999, Journal of biomaterials applications.

[13]  P F Niederer,et al.  A finite element model of the human left ventricular systole , 2006, Computer methods in biomechanics and biomedical engineering.

[14]  S. Göktepe,et al.  Computational modeling of passive myocardium , 2011 .

[15]  A. McCulloch,et al.  Three-dimensional analysis of regional cardiac function: a model of rabbit ventricular anatomy. , 1998, Progress in biophysics and molecular biology.

[16]  Teresa T Wang,et al.  Multi-scale analysis of cardiac myoarchitecture , 2008 .

[17]  Hervé Delingette,et al.  An electromechanical model of the heart for image analysis and simulation , 2006, IEEE Transactions on Medical Imaging.

[18]  Francisco Torrent-Guasp,et al.  The helical ventricular myocardial band: global, three-dimensional, functional architecture of the ventricular myocardium. , 2006, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[19]  P. Hunter,et al.  Integration from proteins to organs: the Physiome Project , 2003, Nature Reviews Molecular Cell Biology.

[20]  Antonio F Corno,et al.  The helical ventricular myocardial band of Torrent-Guasp. , 2007, Seminars in thoracic and cardiovascular surgery. Pediatric cardiac surgery annual.

[21]  Satoshi Nakatani,et al.  Left Ventricular Rotation and Twist: Why Should We Learn? , 2011, Journal of cardiovascular ultrasound.

[22]  W F Whimster,et al.  A silicone rubber mould of the heart. , 1997, Technology and health care : official journal of the European Society for Engineering and Medicine.

[23]  Hany Ghoneim,et al.  Pumping potential of a hyperbolic shell-of-revolution flexible-matrix-composite structure , 2013 .

[24]  Huafeng Liu,et al.  Meshfree implementation of individualized active cardiac dynamics , 2010, Comput. Medical Imaging Graph..

[25]  Mbbs Md FRCPath Donald N. Pritzker Vinay Kumar Robbins and Cotran pathologic basis of disease , 2015 .

[26]  N. Trayanova Whole-heart modeling: applications to cardiac electrophysiology and electromechanics. , 2011, Circulation research.

[27]  Martyn P. Nash,et al.  Mechanics and material properties of the heart using an anatomically accurate mathematical model. , 1998 .

[28]  Gerhard A Holzapfel,et al.  Constitutive modelling of passive myocardium: a structurally based framework for material characterization , 2009, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

[29]  W. Harvey,et al.  AN ANATOMICAL DISQUISITION ON THE MOTION OF THE HEART AND BLOOD IN ANIMALS * , 2000 .

[30]  R. Jonas Seminars in thoracic and cardiovascular surgery : pediatric cardiac surgery annual , 2007 .

[31]  K Wildenthal,et al.  Geometrical studies of the left ventricle utilizing biplane cinefluorography. , 1969, Federation proceedings.