Intensely phosphorescent block copolymer micelles containing gold(i) complexes.

The electrostatic combination of anionic block copolymers with cationic gold(i) complexes leads to the formation of spherical micelles, where gold(i)-containing ionic cores were formed with anionic blocks and further stabilized by neutral blocks of polystyrene or poly(ethylene oxide). This self-assembled strategy induces remarkable phosphorescence enhancement of the gold(i) complexes in solution. The emissive intensity increases unexpectedly with increasing molecular weight of the anionic block that is not coordinated onto the gold(i) complexes. The intensely phosphorescent micelles formed in water can be utilized as a luminescence bioimaging probe in living cells.

[1]  Qun He,et al.  Coordination-driven micellelization of block copolymers with gold(i) complexes induces remarkable phosphorescence enhancements with reversible mechanochromism. , 2018, Soft matter.

[2]  Qun He,et al.  Phosphorescent and semiconductive fiber-like micelles formed by platinum(II) complexes and block copolymers , 2017 .

[3]  Qun He,et al.  Synthesis of platinum(II) complex end functionalized star polymers: luminescence enhancements and unimolecular micelles in solvents of weakened quality , 2017 .

[4]  Nijuan Liu,et al.  Stepwise self-assembly of a block copolymer-platinum(ii) complex hybrid in solvents of variable quality: from worm-like micelles to free-standing sheets to vesicle-like nanostructures. , 2017, Soft matter.

[5]  Nijuan Liu,et al.  Syntheses and Controllable Self-Assembly of Luminescence Platinum(II) Plane-Coil Diblock Copolymers , 2017 .

[6]  Liquan Wang,et al.  Interaction Pathways between Plasma Membrane and Block Copolymer Micelles. , 2017, Biomacromolecules.

[7]  W. Lu,et al.  Reversible Photoactivated Phosphorescence of Gold(I) Arylethynyl Complexes in Aerated DMSO Solutions and Gels. , 2017, Angewandte Chemie.

[8]  Bingran Yu,et al.  Well‐Defined Protein‐Based Supramolecular Nanoparticles with Excellent MRI Abilities for Multifunctional Delivery Systems , 2016 .

[9]  Vonika Ka-Man Au,et al.  Light-Emitting Self-Assembled Materials Based on d(8) and d(10) Transition Metal Complexes. , 2015, Chemical reviews.

[10]  Shaoliang Lin,et al.  Optical properties of amphiphilic copolymer-based self-assemblies , 2015 .

[11]  K. Eliceiri,et al.  Multi-functional self-fluorescent unimolecular micelles for tumor-targeted drug delivery and bioimaging. , 2015, Biomaterials.

[12]  Nijuan Liu,et al.  Self-assembly of star micelle into vesicle in solvents of variable quality: the star micelle retains its core-shell nanostructure in the vesicle. , 2015, Langmuir : the ACS journal of surfaces and colloids.

[13]  Jiuyang Zhang,et al.  Metallopolymers with transition metals in the side-chain by living and controlled polymerization techniques , 2014 .

[14]  D. Yan,et al.  Photo-responsive polymeric micelles. , 2014, Soft matter.

[15]  I. Manners,et al.  Metalloblock Copolymers: New Functional Nanomaterials , 2014 .

[16]  P. Dave,et al.  pH and thermo-responsive tetronic micelles for the synthesis of gold nanoparticles: effect of physiochemical aspects of tetronics. , 2014, Physical chemistry chemical physics : PCCP.

[17]  A. Gennaro,et al.  Dinuclear gold(I) complexes with propylene bridged N-heterocyclic dicarbene ligands: synthesis, structures, and trends in reactivities and properties. , 2013, Dalton transactions.

[18]  Vijender Singh,et al.  Block copolymer micelles as nanoreactors for self-assembled morphologies of gold nanoparticles. , 2013, The journal of physical chemistry. B.

[19]  Katsuhiko Ariga,et al.  Emerging trends in metal-containing block copolymers: synthesis, self-assembly, and nanomanufacturing applications , 2013 .

[20]  Kazuki Yoshii,et al.  Polypeptides-induced self-aggregation and tuning of emission properties of luminescent complexes , 2012 .

[21]  Hassan S. Bazzi,et al.  Luminescent Iridium(III)-Containing Block Copolymers: Self-Assembly into Biotin-Labeled Micelles for Biodetection Assays. , 2012, ACS macro letters.

[22]  C. Che,et al.  Luminescent organogold(III) complexes with long-lived triplet excited states for light-induced oxidative C-H bond functionalization and hydrogen production. , 2012, Angewandte Chemie.

[23]  L. Cavallo,et al.  Blue-emitting dinuclear N-heterocyclic dicarbene gold(I) complex featuring a nearly unit quantum yield. , 2012, Inorganic chemistry.

[24]  H. Schmidbaur,et al.  Aurophilic interactions as a subject of current research: an up-date. , 2012, Chemical Society Reviews.

[25]  J. C. Lima,et al.  Applications of gold(I) alkynyl systems: a growing field to explore. , 2011, Chemical Society reviews.

[26]  Weisheng Liu,et al.  Luminescent polymeric hybrids formed by platinum(II) complexes and block copolymers. , 2011, Chemical communications.

[27]  Kazuki Yoshii,et al.  Luminescent properties of dicyanoaurate(I) aggregates based on electrostatic assembly along poly(allylamine hydrochloride) , 2010 .

[28]  Hassan S. Bazzi,et al.  Ring-Opening Metathesis Polymers for Biodetection and Signal Amplification: Synthesis and Self-Assembly , 2010 .

[29]  C. Bazuin,et al.  Poly(4-vinylpyridine) Derivatives with Diphosphine Complexes of Gold(I) , 2010 .

[30]  N. Mizuno,et al.  Micelles and vesicles formed by polyoxometalate-block copolymer composites. , 2009, Angewandte Chemie.

[31]  V. Yam,et al.  Selective ion probe for Mg2+ based on Au(I)Au(I) interactions in a tripodal alkynylgold(I) complex with oligoether pendants. , 2009, Chemical communications.

[32]  Amitabha Bhattacharyya,et al.  Coinage metal-N-heterocyclic carbene complexes. , 2009, Chemical reviews.

[33]  A. Laguna,et al.  Golden metallopolymers with an active T(1) state via coordination of poly(4-vinyl)pyridine to pentahalophenyl-gold(I) precursors. , 2009, Journal of the American Chemical Society.

[34]  Peng Xu,et al.  Tunable morphologies of rhenium complex-containing polystyrene-block-poly(2-vinylpyridine) aggregates , 2008 .

[35]  Kevin J. T. Noonan,et al.  Phosphorus-containing block copolymer templates can control the size and shape of gold nanostructures. , 2008, Journal of the American Chemical Society.

[36]  J. Mays,et al.  Micellization coupled with facilitation of J-aggregation for poly(1,3-cyclohexadiene)-based amphiphilic block copolymers. , 2008, Soft matter.

[37]  H. Sleiman,et al.  Luminescent Vesicles, Tubules, Bowls, and Star Micelles from Ruthenium−Bipyridine Block Copolymers , 2007 .

[38]  Ka Yan Kitty Man,et al.  Synthesis and characterization of random and block copolymers with pendant rhenium diimine complexes by controlled radical polymerization , 2005 .

[39]  H. Sleiman,et al.  Biotin-Terminated Ruthenium Bipyridine Ring-Opening Metathesis Polymerization Copolymers: Synthesis and Self-Assembly with Streptavidin , 2005 .

[40]  H. Sleiman,et al.  Ruthenium Bipyridine-Containing Polymers and Block Copolymers via Ring-Opening Metathesis Polymerization , 2004 .

[41]  W. Chan,et al.  Polymer aggregates formed by polystyrene-block-poly(4-vinyl-pyridine) functionalized with rhenium(I) 2,2′-bipyridyl complexes , 1999 .

[42]  D. Nguyen,et al.  Effect of Ionic Chain Polydispersity on the Size of Spherical Ionic Microdomains in Diblock Ionomers , 1994 .

[43]  D. Nguyen,et al.  Microphase structure of block ionomers. 3. A SAXS study of the effects of architecture and chemical structure , 1993 .

[44]  M. Doi,et al.  Microdomains in block copolymers and multiplets in ionomers : parallels in behavior , 1993 .