American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control.

This report is being published concurrently in 2009 in Endocrine Practice and Diabetes Care by the American Association of Clinical Endocrinologists and the American Diabetes Association. From the 1Department of Medicine, University of California Los Angeles, Los Angeles, California, 2Department of Medicine, Division of Endocrinology and Metabolism, University of Pittsburgh, Pittsburgh, Pennsylvania, 3Division of Endocrinology and Metabolism, Veterans Affairs Pittsburgh Health Center and University of Pittsburgh School of Nursing PhD Program, Pittsburgh, Pennsylvania, 4Scripps Whittier Diabetes Institute, La Jolla, California, University of California San Diego School of Medicine, San Diego, California, and Diabetes and Endocrine Associates, La Jolla, California, 5Department of Medicine, University of Missouri-Kansas City School of Medicine and Hellman and Rosen Endocrine Associates, North Kansas City, Missouri, 6Department of Medicine, University of Washington School of Medicine, Seattle, Washington, 7Department of Medicine, Section of Endocrinology, Yale University School of Medicine and the Yale Diabetes Center, Yale-New Haven Hospital, New Haven, Connecticut, 8Department of Medicine, Physiology and Biophysics, Division of Clinical and Molecular Endocrinology, Case Western Reserve University, Cleveland, Ohio, 9Clinical Affairs, American Diabetes Association, Alexandria, Virginia, and 10Department of Medicine/Endocrinology, Emory University, Atlanta, Georgia. Address correspondence and reprint requests to Dr. Etie S. Moghissi, 4644 Lincoln Boulevard, Suite 409, Marina del Rey, CA 90292. © 2009 by the American Association of Clinical Endocrinologists and the American Diabetes Association. Abbreviations: AACE = American Association of Clinical Endocrinologists; ACE = American College of Endocrinology; ADA = American Diabetes Association; AMI = acute myocardial infarction; BG = blood glucose; DIGAMI = Diabetes and InsulinGlucose Infusion in Acute Myocardial Infarction; ICUs = intensive care units; IV = intravenous; LOS = length of stay; NICE-SUGAR = Normoglycemia in Intensive

[1]  H. Heath Postural and venous stasis-induced changes in total calcium. , 2005, Mayo Clinic proceedings.

[2]  M. Apkon,et al.  Persistent hyperglycemia in critically ill children. , 2005, The Journal of pediatrics.

[3]  J. Krinsley,et al.  Severe hypoglycemia in critically ill patients: Risk factors and outcomes* , 2007, Critical care medicine.

[4]  F. Bilotta,et al.  Intensive Insulin Therapy After Severe Traumatic Brain Injury: A Randomized Clinical Trial , 2008, Neurocritical care.

[5]  T. Scalea,et al.  Admission hyperglycemia is predictive of outcome in critically ill trauma patients. , 2005, The Journal of trauma.

[6]  R. Tasker,et al.  Glucose level and risk of mortality in pediatric septic shock* , 2005, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[7]  H. Krumholz,et al.  Relationship between spontaneous and iatrogenic hypoglycemia and mortality in patients hospitalized with acute myocardial infarction. , 2009, JAMA.

[8]  V. Montori,et al.  Hyperglycemia in acutely ill patients. , 2002, JAMA.

[9]  G. Umpierrez,et al.  Sliding scale insulin use: myth or insanity? , 2007, The American journal of medicine.

[10]  H. Gerstein,et al.  Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview , 2000, The Lancet.

[11]  J. Seley,et al.  Meeting the Challenge of Inpatient Diabetes Education: An Interdisciplinary Approach , 2009 .

[12]  J. Davidson,et al.  New-Onset Diabetes After Transplantation 2003 International Consensus Guidelines: an endocrinologist's view. , 2004, Diabetes care.

[13]  Richard L. Jones,et al.  Cost analysis of intensive glycemic control in critically ill adult patients. , 2006, Chest.

[14]  D. Bates,et al.  Improving safety with information technology. , 2003, The New England journal of medicine.

[15]  G. Tinkoff,et al.  Admission hyperglycemia as a prognostic indicator in trauma. , 2003, The Journal of trauma.

[16]  S. Shabat,et al.  Prevalence of diabetes mellitus in elderly patients received enteral nutrition long-term care service. , 2008, Archives of gerontology and geriatrics.

[17]  G. Grunkemeier,et al.  Continuous insulin infusion reduces mortality in patients with diabetes undergoing coronary artery bypass grafting. , 2003, The Journal of thoracic and cardiovascular surgery.

[18]  S. Bratton Early Insulin Therapy in Very-Low-Birthweight Infants , 2009 .

[19]  Katsuhiko Kuwa,et al.  Approved IFCC recommendation on reporting results for blood glucose (abbreviated). , 2005, Clinical chemistry.

[20]  A. Donihi,et al.  Effect of a diabetes order set on glycaemic management and control in the hospital , 2008, Quality & Safety in Health Care.

[21]  G. Umpierrez Basal Versus Sliding-Scale Regular Insulin in Hospitalized Patients With Hyperglycemia During Enteral Nutrition Therapy , 2009, Diabetes Care.

[22]  M. Devita,et al.  Evolution of a diabetes inpatient safety committee. , 2006, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[23]  M. Mclean,et al.  The Hyperglycemia: Intensive Insulin Infusion in Infarction (HI-5) study: a randomized controlled trial of insulin infusion therapy for myocardial infarction. , 2006, Diabetes care.

[24]  James D Dziura,et al.  Implementation of a safe and effective insulin infusion protocol in a medical intensive care unit. , 2004, Diabetes care.

[25]  T. D. Kweon,et al.  Intravenous glucose–insulin–potassium during off‐pump coronary artery bypass surgery does not reduce myocardial injury , 2006, Acta anaesthesiologica Scandinavica.

[26]  Susan K Jones,et al.  Hyperglycemia and Infections in Pediatric Trauma Patients , 2008, The American surgeon.

[27]  M. Molitch,et al.  Inpatient management of hyperglycemia: the Northwestern experience. , 2006, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[28]  Steven B Johnson,et al.  Persistent hyperglycemia is predictive of outcome in critically ill trauma patients. , 2005, The Journal of trauma.

[29]  J. Lau,et al.  Insulin therapy for critically ill hospitalized patients: a meta-analysis of randomized controlled trials. , 2004, Archives of internal medicine.

[30]  P. Cryer,et al.  Hypoglycaemia: the limiting factor in the glycaemic management of the critically ill? , 2006, Diabetologia.

[31]  B. Large Providing timely discharge counseling. , 1999, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[32]  M. Siegel,et al.  Glucose control in the ICU--how tight is too tight? , 2009, The New England journal of medicine.

[33]  Etie S Moghissi,et al.  Insulin strategies for managing inpatient and outpatient hyperglycemia and diabetes. , 2008, The Mount Sinai journal of medicine, New York.

[34]  P. Cryer,et al.  Hypoglycemia in diabetes. , 2003, Diabetes care.

[35]  C. Cook,et al.  Continuous subcutaneous insulin infusion (insulin pump) therapy can be safely used in the hospital in select patients. , 2009, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[36]  W. Ricart,et al.  Short-term mortality of myocardial infarction patients with diabetes or hyperglycaemia during admission , 2002, Journal of epidemiology and community health.

[37]  G. Van den Berghe,et al.  Intensive insulin therapy in the medical ICU. , 2006, The New England journal of medicine.

[38]  L. Fogg,et al.  Impact of a subcutaneous insulin protocol in the emergency department: Rush Emergency Department Hyperglycemia Intervention (REDHI). , 2011, The Journal of emergency medicine.

[39]  James Stephen Krinsley,et al.  Effect of an intensive glucose management protocol on the mortality of critically ill adult patients. , 2004, Mayo Clinic proceedings.

[40]  J Wayne Meredith,et al.  Relationship of early hyperglycemia to mortality in trauma patients. , 2004, The Journal of trauma.

[41]  Kimberly A Jameson,et al.  Beliefs About Hospital Diabetes and Perceived Barriers to Glucose Management Among Inpatient Midlevel Practitioners , 2008, The Diabetes educator.

[42]  Steven B. Johnson,et al.  Early hyperglycemic control is important in critically injured trauma patients. , 2007, The Journal of trauma.

[43]  C. Sirio,et al.  Scheduling of Pharmacist-Provided Medication Education for Hospitalized Patients , 2008 .

[44]  C. Saudek,et al.  Antecedent Hyperglycemia Is Associated With an Increased Risk of Neutropenic Infections During Bone Marrow Transplantation , 2008, Diabetes Care.

[45]  S. Braithwaite,et al.  Hospital hypoglycemia: not only treatment but also prevention. , 2004, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[46]  J. Collins,et al.  Early Glucose Normalization Does Not Improve Outcome in the Critically Ill Trauma Population , 2007, The American surgeon.

[47]  Jack Chen,et al.  Inpatient medical errors involving glucose-lowering medications and their impact on patients: review of 2,598 incidents from a voluntary electronic error-reporting database. , 2008, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[48]  C. Tei,et al.  Acute hyperglycemia is associated with adverse outcome after acute myocardial infarction in the coronary intervention era. , 2005, American heart journal.

[49]  G. Grunkemeier,et al.  Continuous intravenous insulin infusion reduces the incidence of deep sternal wound infection in diabetic patients after cardiac surgical procedures. , 1999, The Annals of thoracic surgery.

[50]  F. Brancati,et al.  Glycemic control and sliding scale insulin use in medical inpatients with diabetes mellitus. , 1997, Archives of internal medicine.

[51]  R. Mcnutt,et al.  Eliminating inpatient sliding-scale insulin: a reeducation project with medical house staff. , 2005, Diabetes care.

[52]  P. Jones,et al.  Hyperglycaemia is associated with poor outcomes in patients admitted to hospital with acute exacerbations of chronic obstructive pulmonary disease , 2006, Thorax.

[53]  Jun Zhu,et al.  Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: the CREATE-ECLA randomized controlled trial. , 2005, JAMA.

[54]  Mathijs Vogelzang,et al.  Hyperglycaemic index as a tool to assess glucose control: a retrospective study , 2004, Critical care.

[55]  I. Hirsch,et al.  Hospital management of diabetes. , 2005, Endocrinology and metabolism clinics of North America.

[56]  S. Arbabi,et al.  Mean glucose values predict trauma patient mortality. , 2008, The Journal of trauma.

[57]  A. Donihi,et al.  Implementation of standardized instructions for insulin at hospital discharge. , 2009, Journal of hospital medicine.

[58]  Tracey A. Dechert,et al.  Blood glucose levels at 24 hours after trauma fails to predict outcomes. , 2008, The Journal of trauma.

[59]  J. Donado,et al.  Strict glycaemic control in patients hospitalised in a mixed medical and surgical intensive care unit: a randomised clinical trial , 2008, Critical care.

[60]  Rolf Rossaint,et al.  Intensive insulin therapy and pentastarch resuscitation in severe sepsis. , 2008, The New England journal of medicine.

[61]  David B Sacks,et al.  Tight glucose control in the intensive care unit: are glucose meters up to the task? , 2009, Clinical chemistry.

[62]  F. Toledo,et al.  Insulin Therapy and Glycemic Control in Hospitalized Patients With Diabetes During Enteral Nutrition Therapy , 2009, Diabetes Care.

[63]  K. Malmberg Prospective randomised study of intensive insulin treatment on long term survival after acute myocardial infarction in patients with diabetes mellitus , 1997, BMJ.

[64]  V. Basevi Standards of medical care in diabetes--2007. , 2009, Diabetes care.

[65]  David B Sacks,et al.  A new look at screening and diagnosing diabetes mellitus. , 2008, The Journal of clinical endocrinology and metabolism.

[66]  Aesha Drozdowski,et al.  Standards of medical care in diabetes. , 2004, Diabetes care.

[67]  R. Giugliano,et al.  U-shaped relationship of blood glucose with adverse outcomes among patients with ST-segment elevation myocardial infarction. , 2005, Journal of the American College of Cardiology.

[68]  B A Mizock,et al.  Alterations in carbohydrate metabolism during stress: a review of the literature. , 1995, The American journal of medicine.

[69]  D. Bates,et al.  Effect of computerized physician order entry and a team intervention on prevention of serious medication errors. , 1998, JAMA.

[70]  S. Jabbour,et al.  Diabetes knowledge: are resident physicians and nurses adequately prepared to manage diabetes? , 2007, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[71]  J. Wilberger,et al.  The impact of hyperglycemia on patients with severe brain injury. , 2005, The Journal of trauma.

[72]  J. Mahoney,et al.  Glucose Measurement: Confounding Issues in Setting Targets for Inpatient Management , 2007, Diabetes Care.

[73]  Richard Hellman,et al.  A systems approach to reducing errors in insulin therapy in the inpatient setting. , 2004, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[74]  H. Krumholz,et al.  Admission Glucose and Mortality in Elderly Patients Hospitalized With Acute Myocardial Infarction: Implications for Patients With and Without Recognized Diabetes , 2005, Circulation.

[75]  A. Kitabchi,et al.  Hyperglycemia: an independent marker of in-hospital mortality in patients with undiagnosed diabetes. , 2002, The Journal of clinical endocrinology and metabolism.

[76]  A. Winterstein,et al.  Causes of hyperglycemia and hypoglycemia in adult inpatients. , 2005, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[77]  M. Devita,et al.  Nurse-Directed Protocol for Recognition and Treatment of Hypoglycemia in Hospitalized Patients , 2005 .

[78]  I. Hirsch,et al.  The contribution of malglycemia to mortality among allogeneic hematopoietic cell transplant recipients. , 2009, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

[79]  H Wedel,et al.  Infarction : Long-Term Results From the Diabetes and Insulin-Glucose Infusion Conventionally Treated Patients With Diabetes Mellitus and Acute Myocardial Glycometabolic State at Admission : Important Risk Marker of Mortality in , 1999 .

[80]  Katie Weinger,et al.  Educating your patient with diabetes , 2009 .

[81]  James G. Anderson Improving Patient Safety with Information Technology , 2010 .

[82]  Bruce Buckingham,et al.  Association of Hypoglycemia, Hyperglycemia, and Glucose Variability With Morbidity and Death in the Pediatric Intensive Care Unit , 2006, Pediatrics.

[83]  S. Crawford,et al.  Survey of hospital systems and common serious medication errors. , 1998, Journal of healthcare risk management : the journal of the American Society for Healthcare Risk Management.

[84]  Christopher A. Newton,et al.  Financial implications of glycemic control: results of an inpatient diabetes management program. , 2006, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[85]  J Herlitz,et al.  Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity. , 2005, European heart journal.

[86]  P. Pancorbo-Hidalgo,et al.  Complications associated with enteral nutrition by nasogastric tube in an internal medicine unit. , 2001, Journal of clinical nursing.

[87]  V. Montori,et al.  CONTEMPO UPDATES LINKING EVIDENCE AND EXPERIENCE Hyperglycemia in Acutely Ill Patients , 2002 .

[88]  Limin Peng,et al.  Comparison of inpatient insulin regimens with detemir plus aspart versus neutral protamine hagedorn plus regular in medical patients with type 2 diabetes. , 2009, The Journal of clinical endocrinology and metabolism.

[89]  I. Hirsch,et al.  Should minimal blood glucose variability become the gold standard of glycemic control? , 2005, Journal of diabetes and its complications.

[90]  P. Cryer Diverse causes of hypoglycemia-associated autonomic failure in diabetes. , 2004, The New England journal of medicine.

[91]  Christopher R Palmer,et al.  Early insulin therapy in very-low-birth-weight infants. , 2008, The New England journal of medicine.

[92]  Dario Gregori,et al.  Normal Glucose Values Are Associated With a Lower Risk of Mortality in Hospitalized Patients , 2008, Diabetes Care.

[93]  Jeroen J. Bax,et al.  Increased preoperative glucose levels are associated with perioperative mortality in patients undergoing noncardiac, nonvascular surgery. , 2007, European journal of endocrinology.

[94]  P. Raskin,et al.  Hyperglycemia and acute coronary syndrome: a scientific statement from the American Heart Association Diabetes Committee of the Council on Nutrition, Physical Activity, and Metabolism. , 2008, Circulation.

[95]  M. DiNardo,et al.  The medical emergency team and rapid response system: finding, treating, and preventing hypoglycemia. , 2006, Joint Commission journal on quality and patient safety.

[96]  I. Hirsch,et al.  American College of Endocrinology position statement on inpatient diabetes and metabolic control. , 2004, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[97]  R. Hellman,et al.  Patient safety and inpatient glycemic control: translating concepts into action. , 2006, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[98]  B. Flansbaum Management of hyperglycemia. , 2006, Journal of hospital medicine.

[99]  M. Saul,et al.  Prevalence and predictors of corticosteroid-related hyperglycemia in hospitalized patients. , 2006, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[100]  Jeanne E. Zack,et al.  Efficacy and safety of an insulin infusion protocol in a surgical ICU. , 2006, Journal of the American College of Surgeons.

[101]  Lesly A. Dossett,et al.  Stress insulin resistance is a marker for mortality in traumatic brain injury. , 2009, The Journal of trauma.

[102]  G. Carvalho,et al.  Intensive intraoperative insulin therapy versus conventional glucose management during cardiac surgery. , 2007, Annals of internal medicine.

[103]  L. Rydén,et al.  Admission plasma glucose. Independent risk factor for long-term prognosis after myocardial infarction even in nondiabetic patients. , 1999, Diabetes care.

[104]  J. Krinsley Glycemic control, diabetic status, and mortality in a heterogeneous population of critically ill patients before and during the era of intensive glycemic management: six and one-half years experience at a university-affiliated community hospital. , 2006, Seminars in thoracic and cardiovascular surgery.

[105]  J. Saffle,et al.  Safety and Efficacy of an Intensive Insulin Protocol in a Burn-Trauma Intensive Care Unit , 2008, Journal of burn care & research : official publication of the American Burn Association.

[106]  R. Latham,et al.  The Association of Diabetes and Glucose Control With Surgical-Site Infections Among Cardiothoracic Surgery Patients , 2001, Infection Control & Hospital Epidemiology.

[107]  S. Chow,et al.  Insulin infusion protocols for critically ill patients: a highlight of differences and similarities. , 2007, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[108]  James D Dziura,et al.  Experience with the continuous glucose monitoring system in a medical intensive care unit. , 2004, Diabetes technology & therapeutics.

[109]  Rinaldo Bellomo,et al.  Variability of Blood Glucose Concentration and Short-term Mortality in Critically Ill Patients , 2006, Anesthesiology.

[110]  P. Armstrong,et al.  Prognostic significance of the change in glucose level in the first 24 h after acute myocardial infarction: results from the CARDINAL study. , 2006, European heart journal.

[111]  E. Nylén,et al.  Endocrine Changes in Critical Illness , 2004, Journal of intensive care medicine.

[112]  S. Kripalani,et al.  Promoting effective transitions of care at hospital discharge: a review of key issues for hospitalists. , 2007, Journal of hospital medicine.

[113]  M. Cecilialansang Knowledge on Inpatient Diabetes Among Fourth-Year Medical Students , 2007 .

[114]  A. Murakami,et al.  A Continuous glucose monitoring system in critical cardiac patients in the Intensive Care Unit , 2006, 2006 Computers in Cardiology.

[115]  K. Kouzekanani,et al.  Impact of Postoperative Hyperglycemia following Surgical Repair of Congenital Cardiac Defects , 2008, Pediatric Cardiology.

[116]  T. van der Poll,et al.  Early endotoxemia increases peripheral and hepatic insulin sensitivity in healthy humans. , 2009, The Journal of clinical endocrinology and metabolism.

[117]  Timothy W. Evans,et al.  Glucose Control and Mortality in Critically Ill Patients , 2003 .

[118]  M Schetz,et al.  Intensive insulin therapy in critically ill patients. , 2001, The New England journal of medicine.

[119]  Stephane Heritier,et al.  Intensive versus conventional glucose control in critically ill patients. , 2009, The New England journal of medicine.

[120]  Yingxing Wu,et al.  Effect of hyperglycemia and continuous intravenous insulin infusions on outcomes of cardiac surgical procedures: the Portland Diabetic Project. , 2004, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[121]  R. Zimmerman,et al.  Diabetes care in hospitalized noncritically ill patients: More evidence for clinical inertia and negative therapeutic momentum. , 2007, Journal of hospital medicine.

[122]  H. Gerstein,et al.  Stress Hyperglycemia and Prognosis of Stroke in Nondiabetic and Diabetic Patients: A Systematic Overview , 2001, Stroke.

[123]  Brian H Rowe,et al.  The relation between hyperglycemia and outcomes in 2,471 patients admitted to the hospital with community-acquired pneumonia. , 2005, Diabetes care.

[124]  Greet Van den Berghe,et al.  Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled study , 2009, The Lancet.

[125]  R. Zimmerman,et al.  Diabetes care in the hospital: is there clinical inertia? , 2006, Journal of hospital medicine.

[126]  H. Krumholz,et al.  Glucometrics in Patients Hospitalized With Acute Myocardial Infarction: Defining the Optimal Outcomes-Based Measure of Risk , 2008, Circulation.

[127]  J. Pomposelli,et al.  Early postoperative glucose control predicts nosocomial infection rate in diabetic patients. , 1998, JPEN. Journal of parenteral and enteral nutrition.

[128]  James A. Young,et al.  Outcomes and perioperative hyperglycemia in patients with or without diabetes mellitus undergoing coronary artery bypass grafting. , 2003, The Annals of thoracic surgery.

[129]  Mary T Korytkowski,et al.  Implementing an intravenous insulin infusion protocol in the intensive care unit. , 2007, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[130]  M. Radford,et al.  "Glucometrics"--assessing the quality of inpatient glucose management. , 2006, Diabetes technology & therapeutics.

[131]  P. Devos Impact of tight glucose control by intensive insulin therapy on ICU mortality and the rate of hypoglycaemia : final results of the Glu Control study , 2007 .

[132]  L. Olson,et al.  The benefits of inpatient diabetes care: improving quality of care and the bottom line. , 2006, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[133]  Ace Ada Task Force on Inpatient Diabetes American College of Endocrinology and American Diabetes Association Consensus Statement on Inpatient Diabetes and Glycemic Control , 2006, Diabetes Care.

[134]  J Herlitz,et al.  Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): effects on mortality at 1 year. , 1995, Journal of the American College of Cardiology.

[135]  W. Cooney,et al.  Oncogenic osteomalacia: localization of underlying peripheral mesenchymal tumors with use of Tc 99m sestamibi scintigraphy. , 2006, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[136]  D. Bates,et al.  The Incidence and Severity of Adverse Events Affecting Patients after Discharge from the Hospital , 2003, Annals of Internal Medicine.

[137]  K. Jablonski,et al.  Unrecognized Diabetes Among Hospitalized Patients , 1998, Diabetes Care.

[138]  D. Schroeder,et al.  Hyperglycemia in patients undergoing cerebral aneurysm surgery: its association with long-term gross neurologic and neuropsychological function. , 2008, Mayo Clinic proceedings.

[139]  F. Brancati,et al.  Perioperative glycemic control and the risk of infectious complications in a cohort of adults with diabetes. , 1999, Diabetes care.

[140]  Inpatient management of diabetes and hyperglycemia among general medicine patients at a large teaching hospital. , 2006, Journal of hospital medicine.

[141]  J. Leahy Randomized Study of Basal-Bolus Insulin Therapy in the Inpatient Management of Patients With Type 2 Diabetes (RABBIT 2 Trial) , 2008 .

[142]  G. Van den Berghe,et al.  Analysis of healthcare resource utilization with intensive insulin therapy in critically ill patients* , 2006, Critical care medicine.

[143]  M. Salizzoni,et al.  New-onset diabetes after liver transplantation. , 2005, Transplantation proceedings.

[144]  J C Boyd,et al.  Quality specifications for glucose meters: assessment by simulation modeling of errors in insulin dose. , 2001, Clinical chemistry.

[145]  Richard Hellman,et al.  American College of Endocrinology and American Association of Clinical Endocrinologists position statement on patient safety and medical system errors in diabetes and endocrinology. , 2005, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[146]  M. DiNardo,et al.  Menu selection, glycaemic control and satisfaction with standard and patient-controlled consistent carbohydrate meal plans in hospitalised patients with diabetes , 2010, Quality and Safety in Health Care.

[147]  Darren K Mcguire,et al.  Association between hyper- and hypoglycaemia and 2 year all-cause mortality risk in diabetic patients with acute coronary events. , 2005, European heart journal.

[148]  Anthony Delaney,et al.  Tight glycemic control in critically ill adults. , 2008, JAMA.

[149]  C. Levetan,et al.  Impact of endocrine and diabetes team consultation on hospital length of stay for patients with diabetes. , 1995, The American journal of medicine.

[150]  R. Zimmerman,et al.  Use of Continuous Subcutaneous Insulin Infusion (Insulin Pump) Therapy in the Hospital Setting , 2005, The Diabetes educator.

[151]  I Kiss,et al.  Hierarchy of glycemic thresholds for counterregulatory hormone secretion, symptoms, and cerebral dysfunction. , 1991, The American journal of physiology.

[152]  Poor Glycemic Control Is Associated with Increased Mortality in Critically Ill Trauma Patients , 2009 .

[153]  S. Yamasaki,et al.  Hyperglycemia During the Neutropenic Period Is Associated With a Poor Outcome in Patients Undergoing Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation , 2007, Transplantation.

[154]  A. May,et al.  The impact of a normoglycemic management protocol on clinical outcomes in the trauma intensive care unit. , 2005, JPEN. Journal of parenteral and enteral nutrition.

[155]  G. Grunkemeier,et al.  Glucose control lowers the risk of wound infection in diabetics after open heart operations. , 1997, The Annals of thoracic surgery.

[156]  I. Hirsch Sliding scale insulin--time to stop sliding. , 2009, JAMA.

[157]  G. Umpierrez,et al.  Prevalence and clinical outcome of inpatient hyperglycemia in a community pediatric hospital. , 2008, Journal of hospital medicine.