Monocyte depletion early after stroke promotes neurogenesis from endogenous neural stem cells in adult brain

[1]  O. Lindvall,et al.  Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli , 2017, Brain : a journal of neurology.

[2]  J. E. Lee,et al.  M2 Phenotype Microglia-derived Cytokine Stimulates Proliferation and Neuronal Differentiation of Endogenous Stem Cells in Ischemic Brain , 2017, Experimental neurobiology.

[3]  Manoj Kumar,et al.  INGE GRUNDKE-IQBAL AWARD FOR ALZHEIMER’S RESEARCH: NEUROTOXIC REACTIVE ASTROCYTES ARE INDUCED BY ACTIVATED MICROGLIA , 2019, Alzheimer's & Dementia.

[4]  O. Lindvall,et al.  Transplantation of reprogrammed neurons for improved recovery after stroke. , 2017, Progress in brain research.

[5]  O. Lindvall,et al.  Monocyte-Derived Macrophages Contribute to Spontaneous Long-Term Functional Recovery after Stroke in Mice , 2016, The Journal of Neuroscience.

[6]  Á. Chamorro,et al.  Immature monocytes recruited to the ischemic mouse brain differentiate into macrophages with features of alternative activation , 2016, Brain, Behavior, and Immunity.

[7]  H. Hartung,et al.  Macrophage‐derived osteopontin induces reactive astrocyte polarization and promotes re‐establishment of the blood brain barrier after ischemic stroke , 2015, Glia.

[8]  O. Lindvall,et al.  Inflammation without neuronal death triggers striatal neurogenesis comparable to stroke , 2015, Neurobiology of Disease.

[9]  Paul M. George,et al.  Novel Stroke Therapeutics: Unraveling Stroke Pathophysiology and Its Impact on Clinical Treatments , 2015, Neuron.

[10]  C. Sobey,et al.  Evidence That Ly6Chi Monocytes Are Protective in Acute Ischemic Stroke by Promoting M2 Macrophage Polarization , 2015, Stroke.

[11]  L. McCullough,et al.  Functional differences between microglia and monocytes after ischemic stroke , 2015, Journal of Neuroinflammation.

[12]  G. Fink,et al.  Osteopontin mediates survival, proliferation and migration of neural stem cells through the chemokine receptor CXCR4 , 2015, Stem Cell Research & Therapy.

[13]  M. Chopp,et al.  Beneficial effects of gfap/vimentin reactive astrocytes for axonal remodeling and motor behavioral recovery in mice after stroke , 2014, Glia.

[14]  Jean-Philippe Michaud,et al.  The Impact of Ly6Clow Monocytes after Cerebral Hypoxia-Ischemia in Adult Mice , 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[15]  Michael T. Mullen,et al.  CCR2+Ly6Chi Inflammatory Monocyte Recruitment Exacerbates Acute Disability Following Intracerebral Hemorrhage , 2014, The Journal of Neuroscience.

[16]  Samuel Bernard,et al.  Neurogenesis in the Striatum of the Adult Human Brain , 2014, Cell.

[17]  O. Lindvall,et al.  Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery. , 2013, Brain : a journal of neurology.

[18]  S. Bose,et al.  Role of chemokine CCL2 and its receptor CCR2 in neurodegenerative diseases , 2013, Archives of pharmacal research.

[19]  O. Lindvall,et al.  Grafted human neural stem cells enhance several steps of endogenous neurogenesis and improve behavioral recovery after middle cerebral artery occlusion in rats , 2013, Neurobiology of Disease.

[20]  Timothy J Shafer,et al.  Comparison of chemical-induced changes in proliferation and apoptosis in human and mouse neuroprogenitor cells. , 2012, Neurotoxicology.

[21]  R. Zorec,et al.  Astrocytes Negatively Regulate Neurogenesis Through the Jagged1‐Mediated Notch Pathway , 2012, Stem cells.

[22]  H. Hartung,et al.  Macrophages prevent hemorrhagic infarct transformation in murine stroke models , 2012, Annals of neurology.

[23]  Emanuela Monni,et al.  Human‐Induced Pluripotent Stem Cells form Functional Neurons and Improve Recovery After Grafting in Stroke‐Damaged Brain , 2012, Stem cells.

[24]  F. Sun,et al.  New striatal neurons form projections to substantia nigra in adult rat brain after stroke , 2012, Neurobiology of Disease.

[25]  D. Gomez-Nicola,et al.  Interleukin-15 regulates proliferation and self-renewal of adult neural stem cells , 2011, Molecular biology of the cell.

[26]  M. Prinz,et al.  Tickets to the brain: Role of CCR2 and CX3CR1 in myeloid cell entry in the CNS , 2010, Journal of Neuroimmunology.

[27]  J. García-Verdugo,et al.  Proliferation in the human ipsilateral subventricular zone after ischemic stroke: Neurology 2010;Vol.74:357-365. , 2010, Annals of neurosciences.

[28]  J. García-Verdugo,et al.  Proliferation in the human ipsilateral subventricular zone after ischemic stroke , 2010, Neurology.

[29]  R. Dempsey,et al.  Osteopontin is a mediator of the lateral migration of neuroblasts from the subventricular zone after focal cerebral ischemia , 2009, Neurochemistry International.

[30]  Steffen Jung,et al.  Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice , 2009, PLoS medicine.

[31]  O. Lindvall,et al.  Long‐term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke , 2009, Glia.

[32]  Christian Gerloff,et al.  Temporal and spatial dynamics of cerebral immune cell accumulation in stroke. , 2009, Stroke.

[33]  O. Brüstle,et al.  A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration , 2009, Proceedings of the National Academy of Sciences.

[34]  Ming Xu,et al.  Functional Integration of Newly Generated Neurons Into Striatum After Cerebral Ischemia in the Adult Rat Brain , 2008, Stroke.

[35]  O. Lindvall,et al.  Suppression of Stroke-Induced Progenitor Proliferation in Adult Subventricular Zone by Tumor Necrosis Factor Receptor 1 , 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[36]  PärThored,et al.  Long-Term Neuroblast Migration Along Blood Vessels in an Area With Transient Angiogenesis and Increased Vascularization After Stroke , 2007 .

[37]  P. Eriksson,et al.  Increased Neurogenesis and Astrogenesis from Neural Progenitor Cells Grafted in the Hippocampus of GFAP−/−Vim−/− Mice , 2007, Stem cells.

[38]  R. Dempsey,et al.  Monocyte Chemoattractant Protein-1 Plays a Critical Role in Neuroblast Migration after Focal Cerebral Ischemia , 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[39]  C. Ballard,et al.  Endogenous neurogenesis in the human brain following cerebral infarction. , 2007, Regenerative medicine.

[40]  K. Plate,et al.  Increased Generation of Neuronal Progenitors after Ischemic Injury in the Aged Adult Human Forebrain , 2006, The Journal of Neuroscience.

[41]  R. Dempsey,et al.  Insulin‐like growth factor‐1 is an endogenous mediator of focal ischemia‐induced neural progenitor proliferation , 2006, The European journal of neuroscience.

[42]  H. Okano,et al.  Subventricular Zone-Derived Neuroblasts Migrate and Differentiate into Mature Neurons in the Post-Stroke Adult Striatum , 2006, The Journal of Neuroscience.

[43]  Henrik Ahlenius,et al.  Persistent Production of Neurons from Adult Brain Stem Cells During Recovery after Stroke , 2006, Stem cells.

[44]  M. Chopp,et al.  Stromal Cell-Derived Factor 1α Mediates Neural Progenitor Cell Motility after Focal Cerebral Ischemia , 2006 .

[45]  M. Pekny,et al.  Increased Cell Proliferation and Neurogenesis in the Hippocampal Dentate Gyrus of Old GFAP−/−Vim−/− Mice , 2004, Neurochemical Research.

[46]  Jerry Silver,et al.  Regeneration beyond the glial scar , 2004, Nature Reviews Neuroscience.

[47]  O. Lindvall,et al.  Inflammation is detrimental for neurogenesis in adult brain , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[48]  K. Jin,et al.  VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia. , 2003, The Journal of clinical investigation.

[49]  Jack M Parent,et al.  Rat forebrain neurogenesis and striatal neuron replacement after focal stroke , 2002, Annals of neurology.

[50]  O. Lindvall,et al.  Neuronal replacement from endogenous precursors in the adult brain after stroke , 2002, Nature Medicine.

[51]  E. Jauniaux,et al.  Regional specification of rodent and human neurospheres. , 2002, Brain research. Developmental brain research.

[52]  F. Gage,et al.  Reduced Hippocampal Neurogenesis in Adult Transgenic Mice with Chronic Astrocytic Production of Interleukin-6 , 2002, The Journal of Neuroscience.

[53]  O. Lindvall,et al.  Upregulation of p75 Neurotrophin Receptor after Stroke in Mice Does Not Contribute to Differential Vulnerability of Striatal Neurons , 2001, Experimental Neurology.

[54]  David A. Greenberg,et al.  Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[55]  H. Brühl,et al.  Expression and Characterization of the Chemokine Receptors CCR2 and CCR5 in Mice1 , 2001, The Journal of Immunology.

[56]  R. Galli,et al.  Regulation of Neuronal Differentiation in Human CNS Stem Cell Progeny by Leukemia Inhibitory Factor , 2000, Developmental Neuroscience.

[57]  S. K. Malhotra,et al.  Reactive astrocytes: cellular and molecular cues to biological function , 1997, Trends in Neurosciences.

[58]  J. Zimmer,et al.  Microglial and macrophage reactions mark progressive changes and define the penumbra in the rat neocortex and striatum after transient middle cerebral artery occlusion , 1997 .

[59]  M. Moskowitz,et al.  Reduced Brain Edema and Infarction Volume in Mice Lacking the Neuronal Isoform of Nitric Oxide Synthase after Transient MCA Occlusion , 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.