Analysis of Oct4‐Dependent Transcriptional Networks Regulating Self‐Renewal and Pluripotency in Human Embryonic Stem Cells
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H. Lehrach | R. Herwig | J. Adjaye | T. Burdon | B. Greber | W. Wruck | D. Groth | Y. Babaie | T. Brink | Detlef Groth | Wasco Wruck
[1] R. Pedersen,et al. Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells , 2005, Journal of Cell Science.
[2] Keiji Tanaka,et al. p57Kip2 Regulates Actin Dynamics by Binding and Translocating LIM-kinase 1 to the Nucleus* , 2003, Journal of Biological Chemistry.
[3] H. Schöler,et al. Phage display screening reveals an association between germline-specific transcription factor Oct-4 and multiple cellular proteins. , 2000, Journal of molecular biology.
[4] J. Rossant. Stem Cells from the Mammalian Blastocyst , 2001, Stem cells.
[5] M. Katoh,et al. Molecular cloning and characterization of FRAT2, encoding a positive regulator of the WNT signaling pathway. , 2001, Biochemical and biophysical research communications.
[6] D. Besser. Expression of Nodal, Lefty-A, and Lefty-B in Undifferentiated Human Embryonic Stem Cells Requires Activation of Smad2/3* , 2004, Journal of Biological Chemistry.
[7] H. Schöler,et al. In line with our ancestors: Oct‐4 and the mammalian germ , 1998, BioEssays : news and reviews in molecular, cellular and developmental biology.
[8] Burton B. Yang,et al. Nodal and ALK7 Inhibit Proliferation and Induce Apoptosis in Human Trophoblast Cells* , 2004, Journal of Biological Chemistry.
[9] C. Rodeck,et al. Identification of genes expressed in human primordial germ cells at the time of entry of the female germ line into meiosis. , 1999, Molecular human reproduction.
[10] W. Cleveland. Robust Locally Weighted Regression and Smoothing Scatterplots , 1979 .
[11] Rudolf Jaenisch,et al. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality , 1992, Cell.
[12] M. Murakami,et al. The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells , 2003, Cell.
[13] J. Thomson,et al. Embryonic stem cell lines derived from human blastocysts. , 1998, Science.
[14] P. Robson,et al. Transcriptional Regulation of Nanog by OCT4 and SOX2* , 2005, Journal of Biological Chemistry.
[15] J. Thomson,et al. Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells , 2005, Nature Methods.
[16] L. Szekely,et al. Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts. , 1994, Oncogene.
[17] C. Denning,et al. Human embryonic stem cell methyl cycle enzyme expression: modelling epigenetic programming in assisted reproduction? , 2005, Reproductive biomedicine online.
[18] P. Andrews,et al. Expression of Wnt and Notch pathway genes in a pluripotent human embryonal carcinoma cell line and embryonic stem cells , 2003, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
[19] J. Nichols,et al. Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells , 2003, Cell.
[20] A. Hata,et al. Poly(ADP-ribose) polymerase 1 interacts with OAZ and regulates BMP-target genes. , 2003, Biochemical and biophysical research communications.
[21] Ariel J. Levine,et al. TGFβ/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells , 2005 .
[22] A. Dierich,et al. Apoptosis and differentiation commitment: novel insights revealed by gene profiling studies in mouse embryonic stem cells , 2006, Cell Death and Differentiation.
[23] X. Chen,et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells , 2006, Nature Genetics.
[24] Y. Bergman,et al. A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells , 1995, Molecular and cellular biology.
[25] R. Joshi,et al. Interplay between FGF10 and Notch signalling is required for the self-renewal of pancreatic progenitors. , 2006, The International journal of developmental biology.
[26] Janet Rossant,et al. Interaction between Oct3/4 and Cdx2 Determines Trophectoderm Differentiation , 2005, Cell.
[27] H. Schöler,et al. Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4 , 1998, Cell.
[28] M. Osborne,et al. Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcription. , 2000, Journal of cell science.
[29] J. Nichols,et al. BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3 , 2003, Cell.
[30] John D. Storey. A direct approach to false discovery rates , 2002 .
[31] J. Cross,et al. Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway. , 1997, Developmental genetics.
[32] A. Bird,et al. Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation. , 1999, Genes & development.
[33] Ariel J. Levine,et al. TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. , 2005, Development.
[34] J. Miyazaki,et al. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells , 2000, Nature Genetics.
[35] M. Azim Surani,et al. Reprogramming of genome function through epigenetic inheritance , 2001, Nature.
[36] R. Lovell-Badge,et al. Multipotent cell lineages in early mouse development depend on SOX2 function. , 2003, Genes & development.
[37] F. Gage,et al. Maintenance of embryonic stem cell pluripotency by Nanog-mediated reversal of mesoderm specification , 2006, Nature Clinical Practice Cardiovascular Medicine.
[38] Xi Chen,et al. Reciprocal Transcriptional Regulation of Pou5f1 and Sox2 via the Oct4/Sox2 Complex in Embryonic Stem Cells , 2005, Molecular and Cellular Biology.
[39] Megan F. Cole,et al. Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells , 2005, Cell.
[40] K. Weber,et al. In vitro differentiation of mouse teratocarcinoma cells monitored by intermediate filament expression. , 1982, Differentiation; research in biological diversity.
[41] Austin G Smith,et al. Self-renewal of teratocarcinoma and embryonic stem cells , 2004, Oncogene.
[42] J. Thomson,et al. BMP4 initiates human embryonic stem cell differentiation to trophoblast , 2002, Nature Biotechnology.
[43] J. Thomson,et al. Human ERas Gene Has an Upstream Premature Polyadenylation Signal That Results in a Truncated, Noncoding Transcript , 2005, Stem cells.
[44] M. Nemer,et al. Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6. , 2003, Developmental biology.
[45] P. Andrews,et al. Specific Knockdown of Oct4 and β2‐microglobulin Expression by RNA Interference in Human Embryonic Stem Cells and Embryonic Carcinoma Cells , 2004, Stem cells.
[46] L. Glimcher,et al. Maintenance of mouse trophoblast stem cell proliferation by TGF-beta/activin. , 2004, Developmental biology.
[47] Megan F. Cole,et al. Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells , 2006, Cell.
[48] A. Trounson,et al. Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro , 2000, Nature Biotechnology.
[49] Ralf Herwig,et al. Primary Differentiation in the Human Blastocyst: Comparative Molecular Portraits of Inner Cell Mass and Trophectoderm Cells , 2005, Stem cells.
[50] C. Dehay,et al. Cell Cycle Features of Primate Embryonic Stem Cells , 2006, Stem cells.
[51] J. Thomson,et al. Basic Fibroblast Growth Factor Support of Human Embryonic Stem Cell Self‐Renewal , 2006, Stem cells.
[52] T. Burdon,et al. Oct‐4 Knockdown Induces Similar Patterns of Endoderm and Trophoblast Differentiation Markers in Human and Mouse Embryonic Stem Cells , 2004, Stem cells.
[53] C. Cepko,et al. p27Kip1 and p57Kip2 Regulate Proliferation in Distinct Retinal Progenitor Cell Populations , 2001, The Journal of Neuroscience.
[54] Hiroshi Suzuki,et al. Parp1-deficiency induces differentiation of ES cells into trophoblast derivatives. , 2003, Developmental biology.
[55] L. Glimcher,et al. Maintenance of mouse trophoblast stem cell proliferation by TGF-beta/activin. , 2004, Developmental biology.
[56] A. Pyle,et al. Defining the Role of Wnt/β‐Catenin Signaling in the Survival, Proliferation, and Self‐Renewal of Human Embryonic Stem Cells , 2005, Stem cells.
[57] A. Hampl,et al. Expression and Potential Role of Fibroblast Growth Factor 2 and Its Receptors in Human Embryonic Stem Cells , 2005, Stem cells.
[58] J. Adjaye,et al. Developmental expression of specific genes detected in high-quality cDNA libraries from single human preimplantation embryos. , 1999, Gene.
[59] D. Skalnik,et al. Histone deacetylase activity is required for embryonic stem cell differentiation , 2004, Genesis.
[60] R Herwig,et al. Statistical evaluation of differential expression on cDNA nylon arrays with replicated experiments. , 2001, Nucleic acids research.
[61] S. Aparício,et al. Eomesodermin is required for mouse trophoblast development and mesoderm formation , 2000, Nature.
[62] A. Bird,et al. The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse , 1996, Nature Genetics.
[63] T. Chevassut,et al. Severe Global DNA Hypomethylation Blocks Differentiation and Induces Histone Hyperacetylation in Embryonic Stem Cells , 2004, Molecular and Cellular Biology.
[64] P. Greengard,et al. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor , 2004, Nature Medicine.
[65] Sally Lowell,et al. Notch Promotes Neural Lineage Entry by Pluripotent Embryonic Stem Cells , 2006, PLoS biology.
[66] Tamar Dvash,et al. Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies. , 2004, Human reproduction.