Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism
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R. Soffietti | N. Shemesh | J. Bosch-Barrera | A. Ianuş | L. Paz-Ares | K. Troulé | P. Lorigan | N. Erez | N. Ajenjo | O. Graña-Castro | S. Grivennikov | U. Ricardi | Álvaro González | C. Faria | H. Wikman | A. Calvo | L. Young | D. Varešlija | É. Le Rhun | M. Weller | A. Hernández-Laín | J. Trejo | J. Sepúlveda | A. Siegfried | I. Ferrer | Rocío Suárez | E. Cohen-Jonathan Moyal | M. Artiga | L. Bertero | P. García-Gómez | M. Mohme | J. Aristu | L. Jimenez-Roldan | Á. Pérez-Núñez | S. Keelan | E. Caleiras | J. Fernández-Alén | M. Valiente | E. M. Garrido-Martin | C. Cabañuz | Eva Ortega-Paino | G. Blasco | L. Miarka | Santiago Martin | Luis Miguel Moreno | Patricia Tezanos | P. González-León | Omer Adler | Diana Retana | Eduard Teixidor | E. Sais | R. Lee | C. Dalmasso | Y. Goy | Elisa Cintado | A. Hernández-Martínez | L. Alcázar | C. Fustero-Torre | Pablo Muela | N. Priego | Ana de Pablos-Aragoneses | Cátia Monteiro | M. Perea-García | Laura Álvaro-Espinosa | N. Yebra | Patricia Baena | P. Muela | Olga Esteban | José Mª Mazarico Gallego | A. Hegarty | Cecilia Nuria Maria-Jesus Eva Sobrino Ajenjo Artiga Ortega-Paino | Cecilia Sobrino | Guillermo Blasco | E. Garrido-Martin | Lauritz Miarka | P. Baena | Nuria Ajenjo | Neta Erez | Osvaldo Graña-Castro | E. Cohen-Jonathan Moyal | E. Teixidor | Patricia Tezanos | Clara Cabañuz
[1] Adrian V. Lee,et al. Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities , 2022, Nature communications.
[2] Coral Fustero Torre,et al. bollito: a flexible pipeline for comprehensive single-cell RNA-seq analyses , 2021, Bioinform..
[3] D. Schadendorf,et al. EANO-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumours. , 2021, Annals of oncology : official journal of the European Society for Medical Oncology.
[4] James C. Wright,et al. GENCODE 2021 , 2020, Nucleic Acids Res..
[5] M. Ahluwalia,et al. Current approaches to the management of brain metastases , 2020, Nature Reviews Clinical Oncology.
[6] Z. Wang,et al. Chinese Glioma Genome Atlas (CGGA): A Comprehensive Resource with Functional Genomic Data for Chinese Glioma Patients , 2020, bioRxiv.
[7] L. Liau,et al. 1-[(4-Nitrophenyl)sulfonyl]-4-phenylpiperazine Treatment After Brain Irradiation Preserves Cognitive Function in Mice , 2020, bioRxiv.
[8] R. Scolyer,et al. Adjuvant Whole-Brain Radiation Therapy Compared With Observation After Local Treatment of Melanoma Brain Metastases: A Multicenter, Randomized Phase III Trial. , 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[9] Aviv Regev,et al. A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors , 2019, Nature Medicine.
[10] S. Parpia,et al. Incidence of radionecrosis in single-fraction radiosurgery compared with fractionated radiotherapy in the treatment of brain metastasis. , 2019, Current oncology.
[11] P. Pelicci,et al. XenoCell: classification of cellular barcodes in single cell experiments from xenograft samples , 2019, bioRxiv.
[12] Paul J. Hoffman,et al. Comprehensive Integration of Single-Cell Data , 2018, Cell.
[13] A. Martín-Montalvo,et al. Intergenerational transmission of the positive effects of physical exercise on brain and cognition , 2019, Proceedings of the National Academy of Sciences.
[14] Noam Shemesh,et al. Evaluation of principal component analysis image denoising on multi‐exponential MRI relaxometry , 2019, Magnetic resonance in medicine.
[15] F. Mulero,et al. Intratumoral expression using a NFkB-based promoter enhances IL12 antitumor efficacy , 2019, Cancer Gene Therapy.
[16] Yawei Yuan,et al. Inhibition of NF‐κB improves sensitivity to irradiation and EGFR‐TKIs and decreases irradiation‐induced lung toxicity , 2018, International journal of cancer.
[17] M. Mahdavi,et al. Calprotectin (S100A8/S100A9): a key protein between inflammation and cancer , 2018, Inflammation Research.
[18] A. Redig,et al. Immunotherapy and Symptomatic Radiation Necrosis in Patients With Brain Metastases Treated With Stereotactic Radiation , 2018, JAMA oncology.
[19] M. Rosenblum,et al. Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization , 2018, Nature Cell Biology.
[20] George C Tseng,et al. Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets , 2018, Journal of the National Cancer Institute.
[21] R. Soffietti,et al. STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis , 2018, Nature Medicine.
[22] Z. Zeng,et al. Role of metabolism in cancer cell radioresistance and radiosensitization methods , 2018, Journal of Experimental & Clinical Cancer Research.
[23] P. Brastianos,et al. The Evolving Landscape of Brain Metastasis. , 2018, Trends in cancer.
[24] M. Valiente,et al. Reactive Astrocytes in Brain Metastasis , 2017, Front. Oncol..
[25] P. Wen,et al. NCCN Guidelines Insights: Central Nervous System Cancers, Version 1.2017. , 2017, Journal of the National Comprehensive Cancer Network : JNCCN.
[26] Eudocia Q Lee,et al. Incidence and prognosis of patients with brain metastases at diagnosis of systemic malignancy: a population-based study , 2017, Neuro-oncology.
[27] H. Clevers,et al. Cancer stem cells revisited , 2017, Nature Medicine.
[28] D. Pisano,et al. Nextpresso: Next Generation Sequencing Expression Analysis Pipeline , 2017, Current Bioinformatics.
[29] A. Tutt,et al. Visualization of Tumor-Immune Interaction - Target-Specific Imaging of S100A8/A9 Reveals Pre-Metastatic Niche Establishment , 2017, Theranostics.
[30] N. Vaidehi,et al. Cooperation of neurotrophin receptor TrkB and Her2 in breast cancer cells facilitates brain metastases , 2017, Breast Cancer Research.
[31] Alexander Radbruch,et al. Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO) , 2017, Neuro-oncology.
[32] Jan Sijbers,et al. Denoising of diffusion MRI using random matrix theory , 2016, NeuroImage.
[33] Ruth E Langley,et al. Dexamethasone and supportive care with or without whole brain radiotherapy in treating patients with non-small cell lung cancer with brain metastases unsuitable for resection or stereotactic radiotherapy (QUARTZ): results from a phase 3, non-inferiority, randomised trial , 2016, The Lancet.
[34] W. Woodward,et al. Computational Modeling of Micrometastatic Breast Cancer Radiation Dose Response. , 2016, International journal of radiation oncology, biology, physics.
[35] Volker W Stieber,et al. Effect of Radiosurgery Alone vs Radiosurgery With Whole Brain Radiation Therapy on Cognitive Function in Patients With 1 to 3 Brain Metastases: A Randomized Clinical Trial. , 2016, JAMA.
[36] J. Massagué,et al. Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer , 2016, Nature.
[37] Andrew D. Rouillard,et al. Enrichr: a comprehensive gene set enrichment analysis web server 2016 update , 2016, Nucleic Acids Res..
[38] R. Muschel,et al. Tumor-infiltrating monocytes/macrophages promote tumor invasion and migration by upregulating S100A8 and S100A9 expression in cancer cells , 2016, Oncogene.
[39] Yibin Kang,et al. Distinctive properties of metastasis-initiating cells , 2016, Genes & development.
[40] Elisa de Stanchina,et al. Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT , 2016, Cell.
[41] J. Hainfellner,et al. Descriptive statistical analysis of a real life cohort of 2419 patients with brain metastases of solid cancers , 2016, ESMO Open.
[42] Boudewijn P. F. Lelieveldt,et al. Morphological maturation of the mouse brain: An in vivo MRI and histology investigation , 2016, NeuroImage.
[43] H. Cameron,et al. Analysis of radiation therapy in a model of triple-negative breast cancer brain metastasis , 2015, Clinical & Experimental Metastasis.
[44] Julien Cohen-Adad,et al. Real diffusion-weighted MRI enabling true signal averaging and increased diffusion contrast , 2015, NeuroImage.
[45] Bibek Dhital,et al. Gibbs‐ringing artifact removal based on local subvoxel‐shifts , 2015, Magnetic resonance in medicine.
[46] S. Choi,et al. TopBP1 and Claspin contribute to the radioresistance of lung cancer brain metastases , 2014, Molecular Cancer.
[47] M. Kris,et al. Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis , 2014, Cell.
[48] B. Ross,et al. Mathematical Modeling of PDGF-Driven Glioblastoma Reveals Optimized Radiation Dosing Schedules , 2014, Cell.
[49] M. Sabbagh,et al. Effect of TTP488 in patients with mild to moderate Alzheimer’s disease , 2014, BMC Neurology.
[50] Se Hoon Kim,et al. Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma. , 2013, Cancer cell.
[51] Joshua M. Stuart,et al. The Cancer Genome Atlas Pan-Cancer analysis project , 2013, Nature Genetics.
[52] David G. Kirsch,et al. Strategies for optimizing the response of cancer and normal tissues to radiation , 2013, Nature Reviews Drug Discovery.
[53] E. Chen,et al. Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool , 2013, BMC Bioinformatics.
[54] Benjamin E. Gross,et al. Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal , 2013, Science Signaling.
[55] À. Sierra,et al. Development of a Preclinical Therapeutic Model of Human Brain Metastasis with Chemoradiotherapy , 2013, International journal of molecular sciences.
[56] D. Nam,et al. Radiosensitization of brain metastasis by targeting c-MET , 2013, Laboratory Investigation.
[57] S. Schildge,et al. Isolation and culture of mouse cortical astrocytes. , 2013, Journal of visualized experiments : JoVE.
[58] V. Seshan,et al. A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis , 2012, Cell.
[59] Benjamin E. Gross,et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. , 2012, Cancer discovery.
[60] Hiroshi Yamamoto,et al. RAGE mediates vascular injury and inflammation after global cerebral ischemia , 2012, Neurochemistry International.
[61] Edi Brogi,et al. Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs , 2011, Nature Medicine.
[62] Douglas Galasko,et al. PF-04494700, an Oral Inhibitor of Receptor for Advanced Glycation End Products (RAGE), in Alzheimer Disease , 2011, Alzheimer disease and associated disorders.
[63] R. Jain,et al. The biology of brain metastases—translation to new therapies , 2011, Nature Reviews Clinical Oncology.
[64] K. Aldape,et al. Reactive astrocytes protect melanoma cells from chemotherapy by sequestering intracellular calcium through gap junction communication channels. , 2010, Neoplasia.
[65] Cole Trapnell,et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. , 2010, Nature biotechnology.
[66] Jens Frahm,et al. MRI of cellular layers in mouse brain in vivo , 2009, NeuroImage.
[67] T. Wurdinger,et al. Real-Time Monitoring of Nuclear Factor κB Activity in Cultured Cells and in Animal Models , 2009, Molecular imaging.
[68] P. Yaswen,et al. A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells , 2009, PloS one.
[69] Marc Ladanyi,et al. WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis , 2009, Cell.
[70] Gonçalo R. Abecasis,et al. The Sequence Alignment/Map format and SAMtools , 2009, Bioinform..
[71] W. Gerald,et al. Genes that mediate breast cancer metastasis to the brain , 2009, Nature.
[72] Lior Pachter,et al. Sequence Analysis , 2020, Definitions.
[73] Cole Trapnell,et al. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome , 2009, Genome Biology.
[74] K. Tracey,et al. The HMGB1 Receptor RAGE Mediates Ischemic Brain Damage , 2008, The Journal of Neuroscience.
[75] Jacqueline N. Crawley,et al. What's Wrong With My Mouse? , 2007 .
[76] Hiroyuki Aburatani,et al. Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis , 2006, Nature Cell Biology.
[77] Hiroki Shirato,et al. Stereotactic Radiosurgery Plus Whole-Brain Radiation Therapy vs Stereotactic Radiosurgery Alone for Treatment of Brain Metastases: A Randomized Controlled Trial , 2007 .
[78] D. Mayer,et al. S100A8 and S100A9 activate MAP kinase and NF-kappaB signaling pathways and trigger translocation of RAGE in human prostate cancer cells. , 2006, Experimental cell research.
[79] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[80] A. Morton,et al. RAGE is expressed in pyramidal cells of the hippocampus following moderate hypoxic–ischemic brain injury in rats , 2003, Brain Research.
[81] M. Monje,et al. Irradiation induces neural precursor-cell dysfunction , 2002, Nature Medicine.
[82] Torsten Hothorn,et al. On the Exact Distribution of Maximally Selected Rank Statistics , 2002, Comput. Stat. Data Anal..
[83] B Olivier,et al. Use of score sheets for welfare assessment of transgenic mice , 2001, Laboratory animals.
[84] Z. Makita,et al. Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer’s disease , 2001, Brain Research.
[85] W R Markesbery,et al. Postoperative radiotherapy in the treatment of single metastases to the brain: a randomized trial. , 1998, JAMA.
[86] E. Rakovitch,et al. Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases. , 2018, The Cochrane database of systematic reviews.
[87] M. Sabbagh,et al. Development of Azeliragon, an Oral Small Molecule Antagonist of the Receptor for Advanced Glycation Endproducts, for the Potential Slowing of Loss of Cognition in Mild Alzheimer’s Disease , 2018, The Journal of Prevention of Alzheimer's Disease.
[88] R. Verhaak,et al. GlioVis data portal for visualization and analysis of brain tumor expression datasets. , 2017, Neuro-oncology.
[89] Thomas R. Gingeras,et al. STAR: ultrafast universal RNA-seq aligner , 2013, Bioinform..
[90] J. Redondo,et al. IL10 released by a new inflammation-regulated lentiviral system efficiently attenuates zymosan-induced arthritis. , 2013, Molecular therapy : the journal of the American Society of Gene Therapy.