A defect in DNA double strand break processing in cells from unaffected parents of retinoblastoma patients and other apparently normal humans.
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Takamitsu A Kato | J. Little | J. Bedford | H. Nagasawa | M. Weil | P. F. Wilson | M. Fitzek | Takamitsu A. Kato
[1] J. Bedford,et al. Studies on chromosome aberration induction: what can they tell us about DNA repair? , 2006, DNA repair.
[2] Takamitsu A Kato,et al. Levels of γ-H2AX Foci after Low-Dose-Rate Irradiation Reveal a DNA DSB Rejoining Defect in Cells from Human ATM Heterozygotes in Two AT Families and in Another Apparently Normal Individual , 2006, Radiation research.
[3] Takamitsu A Kato,et al. γ-H2AX Foci after Low-Dose-Rate Irradiation Reveal Atm Haploinsufficiency in Mice , 2006, Radiation research.
[4] James B. Mitchell,et al. Abnormal gene expression profiles in unaffected parents of patients with hereditary-type retinoblastoma. , 2006, Cancer research.
[5] E. Dikomey,et al. Huge differences in cellular radiosensitivity due to only very small variations in double-strand break repair capacity , 2005, International journal of radiation biology.
[6] J. Gray,et al. The genetics and genomics of cancer , 2003, Nature Genetics.
[7] M. Cornforth,et al. Dose Responses for Chromosome Aberrations Produced in Noncycling Primary Human Fibroblasts by Alpha Particles, and by Gamma Rays Delivered at Sublimiting Low Dose Rates , 2002, Radiation research.
[8] J. Little,et al. Unexpected sensitivity to radiation of fibroblasts from unaffected parents of children with hereditary retinoblastoma , 2002, International Journal of Cancer.
[9] Douglas F. Easton,et al. Polygenic susceptibility to breast cancer and implications for prevention , 2002, Nature Genetics.
[10] J. Overgaard,et al. Relationship between DNA double-strand breaks, cell killing, and fibrosis studied in confluent skin fibroblasts derived from breast cancer patients. , 2000, International journal of radiation oncology, biology, physics.
[11] D. Evans,et al. Heritability of cellular radiosensitivity: a marker of low-penetrance predisposition genes in breast cancer? , 1999, American journal of human genetics.
[12] P. Jeggo,et al. Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20. , 1998, Nucleic acids research.
[13] T. Dryja,et al. Quantification of the paternal allele bias for new germline mutations in the retinoblastoma gene , 1994, Human Genetics.
[14] K. Ishizaki,et al. Parental origin of germ-line and somatic mutations in the retinoblastoma gene , 1994, Human Genetics.
[15] J. Bedford,et al. An ionizing radiation-sensitive mutant of CHO cells: irs-20. III. Chromosome aberrations, DNA breaks and mitotic delay. , 1994, International journal of radiation biology.
[16] P. Deschavanne,et al. A benchmark of cell survival models using survival curves for human cells after completion of repair of potentially lethal damage. , 1994, Radiation research.
[17] J. Bedford,et al. An ionizing radiation-sensitive mutant of CHO cells: irs-20. II. Dose-rate effects and cellular recovery processes. , 1993, Radiation research.
[18] D. Lloyd,et al. Chromosomal aberrations in human lymphocytes induced in vitro by very low doses of X-rays. , 1992, International journal of radiation biology.
[19] K. Ishizaki,et al. Somatic and germinal mutations of tumor-suppressor genes in the development of cancer. , 1991, Journal of radiation research.
[20] G. Iliakis,et al. Kinetics of DNA double-strand break repair throughout the cell cycle as assayed by pulsed field gel electrophoresis in CHO cells. , 1991, International journal of radiation biology.
[21] A. Giaccia,et al. scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[22] W. Benedict,et al. Preferential retention of paternal alleles in human retinoblastoma: evidence for genomic imprinting. , 1990, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[23] A. Goddard,et al. Preferential germline mutation of the paternal allele in retinoblastoma , 1989, Nature.
[24] T. Dryja,et al. Parental origin of mutations of the retinoblastoma gene , 1989, Nature.
[25] A. Giaccia,et al. An asymmetric field inversion gel electrophoresis method for the separation of large DNA molecules. , 1989, Analytical biochemistry.
[26] J. Little,et al. Radiosensitivities of ten apparently normal human diploid fibroblast strains to cell killing, G2-phase chromosomal aberrations, and cell cycle delay. , 1988, Cancer research.
[27] M. Sasaki,et al. Types, rates, origin and expressivity of chromosome mutations involving 13q14 in retinoblastoma patients , 1988, Human Genetics.
[28] M N Cornforth,et al. Relationship between the recovery from sublethal X-ray damage and the rejoining of chromosome breaks in normal human fibroblasts. , 1987, Radiation research.
[29] M N Cornforth,et al. A quantitative comparison of potentially lethal damage repair and the rejoining of interphase chromosome breaks in low passage normal human fibroblasts. , 1987, Radiation research.
[30] R. Parshad,et al. Chromosomal radiosensitivity during the G2 cell-cycle period of skin fibroblasts from individuals with familial cancer. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[31] J. Bedford,et al. On the nature of a defect in cells from individuals with ataxia-telangiectasia. , 1985, Science.
[32] R. Parshad,et al. Chromatid damage after G2 phase x-irradiation of cells from cancer-prone individuals implicates deficiency in DNA repair. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[33] J. Bedford,et al. Dose-rate effects in mammalian cells. IV. Repairable and nonrepairable damage in noncycling C3H 10T 1/2 cells. , 1983, Radiation research.
[34] D. Blöcher,et al. DNA double strand breaks in Ehrlich ascites tumour cells at low doses of x-rays. II. Can cell death be attributed to double strand breaks? , 1982, International journal of radiation biology and related studies in physics, chemistry, and medicine.
[35] R. Pedersen,et al. Repair of the ultraviolet-irradiated male genome in fertilized mouse eggs. , 1981, Science.
[36] J. Bedford,et al. Dose-rate effects in mammalian cells in culture III. Comparison of cell killing and cell proliferation during continuous irradiation for six different cell lines. , 1979, Radiation research.
[37] M. Bender,et al. Mechanisms of chromosomal aberration production. 3. Chemicals and ionizing radiation. , 1974, Mutation research.
[38] J. G. Brewen,et al. X-ray induced translocations in spermatogonia. I. Dose and fractionation responses in mice. , 1973, Mutation research.
[39] M. Lyon,et al. Induction of translocations in mouse spermatogonia by X-ray doses divided into many small fractions. , 1970, Mutation research.
[40] J. Little. Repair of Sub-lethal and Potentially Lethal Radiation Damage in Plateau Phase Cultures of Human Cells , 1969, Nature.
[41] H. Kaplan,et al. Radiosensitization Of E. Coli by Purine and Pyrimidine Analogues Incorporated in Deoxyribonucleic Acid , 1961, Nature.
[42] P. Pharoah. Genetic susceptibility, predicting risk and preventing cancer. , 2003, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.
[43] Bruce A.J. Ponder,et al. Cancer genetics , 2001, Nature.
[44] S. Roberts,et al. Increased chromosomal radiosensitivity in breast cancer patients: a comparison of two assays. , 1999, International journal of radiation biology.
[45] J. Fraumeni,et al. Cancer incidence after retinoblastoma. Radiation dose and sarcoma risk. , 1997, JAMA.
[46] P. Deschavanne,et al. A review of human cell radiosensitivity in vitro. , 1996, International journal of radiation oncology, biology, physics.
[47] S. Roberts,et al. Chromosomal radiosensitivity in G2-phase lymphocytes as an indicator of cancer predisposition. , 1996, Radiation research.
[48] R. Cowan,et al. Identification of A-T heterozygotes , 1993 .
[49] J. Bedford,et al. Ionizing Radiation Damage and Its Early Development in Chromosomes , 1993 .
[50] R. Okayasu,et al. Radiosensitivity throughout the cell cycle and repair of potentially lethal damage and DNA double-strand breaks in an X-ray-sensitive CHO mutant. , 1990, International journal of radiation biology.
[51] D. Blöcher,et al. CHEF electrophoresis, a sensitive technique for the determination of DNA double-strand breaks. , 1989, International journal of radiation biology.
[52] J. Little,et al. Effect of confluent holding on potentially lethal damage repair, cell cycle progression, and chromosomal aberrations in human normal and ataxia-telangiectasia fibroblasts. , 1985, Radiation research.
[53] B. Bridges,et al. Ataxia telangiectasia: A cellular and molecular link between cancer, neuropathology, and immune deficiency , 1982 .
[54] W. Generoso,et al. Genetic lesions induced by chemicals in spermatozoa and spermatids of mice are repaired in the egg. , 1979, Proceedings of the National Academy of Sciences of the United States of America.
[55] W. Szybalski,et al. Molecular Radiobiology of Human Cell Lines: III. Radiation-sensitizing Properties of 5-Iododeoxyuridine , 1963 .