Facile synthesis of flower like copper oxide and their application to hydrogen peroxide and nitrite sensing

BackgroundThe detection of hydrogen peroxide (H2O2) and nitrite ion (NO2-) is of great important in various fields including clinic, food, pharmaceutical and environmental analyses. Compared with many methods that have been developed for the determination of them, the electrochemical detection method has attracted much attention. In recent years, with the development of nanotechnology, many kinds of micro/nano-scale materials have been used in the construction of electrochemical biosensors because of their unique and particular properties. Among these catalysts, copper oxide (CuO), as a well known p-type semiconductor, has gained increasing attention not only for its unique properties but also for its applications in many fields such as gas sensors, photocatalyst and electrochemistry sensors. Continuing our previous investigations on transition-metal oxide including cuprous oxide and α-Fe2O3 modified electrode, in the present paper we examine the electrochemical and electrocatalytical behavior of flower like copper oxide modified glass carbon electrodes (CuO/GCE).ResultsFlower like copper oxide (CuO) composed of many nanoflake was synthesized by a simple hydrothermal reaction and characterized using field-emission scanning electron microscopy (FE-SEM) and X-ray diffraction (XRD). CuO modified glass carbon electrode (CuO/GCE) was fabricated and characterized electrochemically. A highly sensitive method for the rapid amperometric detection of hydrogen peroxide (H2O2) and nitrite (NO2-) was reported.ConclusionsDue to the large specific surface area and inner characteristic of the flower like CuO, the resulting electrode show excellent electrocatalytic reduction for H2O2 and oxidation of NO2-. Its sensitivity, low detection limit, fast response time and simplicity are satisfactory. Furthermore, this synthetic approach can also be applied for the synthesis of other inorganic oxides with improved performances and they can also be extended to construct other micro/nano-structured functional surfaces.

[1]  Lei Wang,et al.  A method for the production of reduced graphene oxide using benzylamine as a reducing and stabilizing agent and its subsequent decoration with Ag nanoparticles for enzymeless hydrogen peroxide detection , 2011 .

[2]  C. Banks,et al.  Copper Oxide – Graphite Composite Electrodes: Application to Nitrite Sensing , 2007 .

[3]  Yuehe Lin,et al.  Low-potential amperometric determination of hydrogen peroxide with a carbon paste electrode modified with nanostructured cryptomelane-type manganese oxides , 2005 .

[4]  Aleksandra Lobnik,et al.  Sol–gel based optical sensor for continuous determination of dissolved hydrogen peroxide , 2001 .

[5]  Bin Xu,et al.  A highly sensitive hydrogen peroxide amperometric sensor based on MnO2-modified vertically aligned multiwalled carbon nanotubes. , 2010, Analytica chimica acta.

[6]  Yan Peng,et al.  An ether sensor utilizing cataluminescence on nanosized ZnWO4 , 2009 .

[7]  S. Epstein,et al.  Nitrosamines as Environmental Carcinogens , 1970, Nature.

[8]  E. C. Hurdis,et al.  Accuracy of Determination of Hydrogen Peroxide by Cerate Oxidimetry , 1954 .

[9]  Jianwei Guo,et al.  Electrocatalytical Oxidation of Nitrite and Its Determination Based on Au@Fe3O4 Nanoparticles , 2010 .

[10]  A. Abbaspour,et al.  Electrocatalytic activity of Ce(III)-EDTA complex toward the oxidation of nitrite ion. , 2005, Talanta.

[11]  Shengshui Hu,et al.  Direct electrochemistry of hemoglobin in PHEA and its catalysis to H2O2. , 2007, Biosensors & bioelectronics.

[12]  Li Wang,et al.  A novel hydrogen peroxide sensor based on horseradish peroxidase immobilized on colloidal Au modified ITO electrode , 2004 .

[13]  G. Rivas,et al.  Glucose biosensors based on the immobilization of copper oxide and glucose oxidase within a carbon paste matrix. , 2005, Talanta.

[14]  Ying Wang,et al.  A highly sensitive hydrogen peroxide amperometric sensor based on MnO2 nanoparticles and dihexadecyl hydrogen phosphate composite film , 2006 .

[15]  Qin Xu,et al.  Electrochemical determination of nitrite based on poly(amidoamine) dendrimer-modified carbon nanotubes for nitrite oxidation , 2009 .

[16]  M. Cardosi,et al.  Evaluation of phenolic assays for the detection of nitrite. , 1999, Talanta.

[17]  I. Wolff,et al.  Nitrates, nitrites, and nitrosamines. , 1972, Science.

[18]  Jing Gu,et al.  An unusual H2O2 electrochemical sensor based on Ni(OH)2 nanoplates grown on Cu substrate , 2010 .

[19]  Danila Moscone,et al.  Prussian Blue and enzyme bulk-modified screen-printed electrodes for hydrogen peroxide and glucose determination with improved storage and operational stability , 2003 .

[20]  Lun Wang,et al.  Electrochemical determination of nitrite and iodate by use of gold nanoparticles/poly(3-methylthiophene) composites coated glassy carbon electrode , 2008 .

[21]  W. Vastarella,et al.  Enzyme/semiconductor nanoclusters combined systems for novel amperometric biosensors. , 2005, Talanta.

[22]  Lun Wang,et al.  Layered double hydroxides functionalized with anionic surfactant: Direct electrochemistry and electrocatalysis of hemoglobin , 2008 .

[23]  Xia Qin,et al.  Synthesis of dendritic silver nanostructures and their application in hydrogen peroxide electroreduction , 2011 .

[24]  Y. Huang,et al.  A study on carcinogenesis of endogenous nitrite and nitrosamine, and prevention of cancer. , 1996, Mutation research.

[25]  L. A. Patil,et al.  CuO-doped BSST thick film resistors for ppb level H2S gas sensing at room temperature , 2007 .

[26]  Sudip Chakraborty,et al.  Pt nanoparticle-based highly sensitive platform for the enzyme-free amperometric sensing of H2O2. , 2009, Biosensors & bioelectronics.

[27]  Guangchao Zhao,et al.  Direct electrocatalytic oxidation of nitric oxide and reduction of hydrogen peroxide based on alpha-Fe2O3 nanoparticles-chitosan composite. , 2010, Talanta.

[28]  C. Banks,et al.  Manganese Dioxide Graphite Composite Electrodes: Application to the Electroanalysis of Hydrogen Peroxide, Ascorbic Acid and Nitrite , 2007, Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.

[29]  Zong Dai,et al.  Construction of Au nanoparticles on choline chloride modified glassy carbon electrode for sensitive detection of nitrite. , 2009, Biosensors & bioelectronics.

[30]  Li Wang,et al.  A novel hydrogen peroxide sensor based on Ag nanoparticles electrodeposited on DNA-networks modified glassy carbon electrode , 2008 .

[31]  C. R. Raj,et al.  Mercaptoethylpyrazine promoted electrochemistry of redox protein and amperometric biosensing of uric acid. , 2007, Biosensors & bioelectronics.

[32]  R. Compton,et al.  Detection and determination of nitrate and nitrite: a review. , 2001, Talanta.

[33]  U. Karst,et al.  Simultaneous HPLC determination of peroxyacetic Acid and hydrogen peroxide. , 1997, Analytical chemistry.

[34]  Yueming Li,et al.  Direct electrochemistry of hemoglobin immobilized in CuO nanowire bundles. , 2010, Talanta.

[35]  Genxi Li,et al.  A hydrogen peroxide biosensor based on the bioelectrocatalysis of hemoglobin incorporated in a kieselgubr film , 2002 .

[36]  Y. Chai,et al.  Direct electrocatalytic reduction of hydrogen peroxide based on Nafion and copper oxide nanoparticles modified Pt electrode , 2008 .

[37]  Xiangting Dong,et al.  Silver microspheres for application as hydrogen peroxide sensor , 2009 .

[38]  G. Raspi,et al.  Voltammetric behavior of nitrite ion on platinum in neutral and weakly acidic media. , 1972, Analytical chemistry.

[39]  J. Zen,et al.  Flow injection analysis of hydrogen peroxide on copper-plated screen-printed carbon electrodes , 2000 .

[40]  Q. Li,et al.  A novel non-enzymatic hydrogen peroxide sensor based on Mn-nitrilotriacetate acid (Mn-NTA) nanowires. , 2010, Talanta.

[41]  M. Gatta,et al.  Electrochemical reduction of NO3− and NO2− on a composite copper thallium electrode in alkaline solutions , 2004 .

[42]  B. Jena,et al.  Enzyme integrated silicate-Pt nanoparticle architecture: a versatile biosensing platform. , 2011, Biosensors & bioelectronics.

[43]  C. Xia,et al.  Facile synthesis of novel MnO2 hierarchical nanostructures and their application to nitrite sensing , 2009 .

[44]  Kaiming Liao,et al.  Porous cuprous oxide microcubes for non-enzymatic amperometric hydrogen peroxide and glucose sensing , 2009 .

[45]  E. Grabner,et al.  Copper Hexacyanoferrate-Modified Glassy Carbon: A Novel Type of Potassium-Selective Electrode , 1985 .

[46]  M. Guardia,et al.  A portable and low cost equipment for flow injection chemiluminescence measurements. , 2005, Talanta.

[47]  R. Zhou,et al.  Comparative study of different methods of preparing CuO-CeO2 catalysts for preferential oxidation of CO in excess hydrogen , 2007 .

[48]  C. R. Raj,et al.  Development of an Amperometric Cholesterol Biosensor Based on Graphene-Pt Nanoparticle Hybrid Material , 2010 .

[49]  Haoqing Hou,et al.  Electrospun Palladium Nanoparticle‐Loaded Carbon Nanofibers and Their Electrocatalytic Activities towards Hydrogen Peroxide and NADH , 2008 .

[50]  Itamar Willner,et al.  Nucleic acid-functionalized Pt nanoparticles: Catalytic labels for the amplified electrochemical detection of biomolecules. , 2006, Analytical chemistry.

[51]  Richard G. Compton,et al.  Electrochemical detection of nitrate and nitrite at a copper modified electrode , 2000 .