Large area CCD based imaging system for mammography

The authors have recently developed a digital X-ray imaging system based on a high resolution scintillator screen optically coupled to a specially designed large area CCD for use in mammographic procedures. The CCD consists of a 7 K/spl times/4 K array of 12 /spl mu/m pixels, measuring 88.2 mm/spl times/51 mm and operated at room temperature, cooled only by ambient air circulation. With 12 /spl mu/m pixels, the resulting limiting Nyquist frequency is 41.6 lp/mm. The readout electronics and software are designed to capture images with the full CCD resolution as well as with binning. Depending on the requirements of the application, the CCD may be binned in the 2/spl times/2 or the 4/spl times/4 configuration. Since the time required to read 28 million pixels is large, binning provides an option for rapid image acquisition at a reduced resolution. A fiberoptic faceplate is optically bonded to the CCD to simplify coupling of scintillator screens to the sensor. One important feature of the system is the lack of a fiberoptic taper, making the system smaller and easier to handle or move. Structured CsI(Tl) scintillator screens developed at RMD Inc., were used for the system evaluation. This paper discusses the system design, the characterization of the CCD sensor as well as the imaging performance of the system using mammography phantoms.

[1]  Y. Klugerman,et al.  High speed X-ray imaging camera using structured CsI(Tl) scintillator , 1998, 1998 IEEE Nuclear Science Symposium Conference Record. 1998 IEEE Nuclear Science Symposium and Medical Imaging Conference (Cat. No.98CH36255).

[2]  Edwin Silverberg,et al.  Survival experience in the breast cancer detection demonstration project , 1987, CA: a cancer journal for clinicians.

[3]  S. Moss,et al.  Benefits versus risks from mammography. A critical reassessment. , 1997, Cancer.

[4]  F. Shtern Digital mammography and related technologies: a perspective from the National Cancer Institute. , 1992, Radiology.

[5]  A Fenster,et al.  Scanned-projection digital mammography. , 1987, Medical physics.

[6]  M. Yaffe,et al.  Signal-to-noise properties of mammographic film-screen systems. , 1985, Medical physics.

[7]  R Fahrig,et al.  Dynamic range requirements in digital mammography. , 1993, Medical physics.

[8]  P. Rodnyi Physical Processes in Inorganic Scintillators , 2020 .

[9]  Michael R. Squillante,et al.  High speed X-ray imaging camera using a structured CsI(Tl) scintillator , 1998 .

[10]  C A Kelsey,et al.  Benefits versus risks from mammography: A critical reasessment , 1996, Cancer.

[11]  Michael R. Squillante,et al.  Structured CsI(Tl) scintillators for X-ray imaging applications , 1997 .

[12]  Paul R. Granfors Performance characteristics of an amorphous silicon flat-panel x-ray imaging detector , 1999, Medical Imaging.

[13]  C. D'Orsi,et al.  On line for digital mammography , 1995, The Lancet.