Structure, ligands, and roles of GPR126/ADGRG6 in the development and diseases
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Mengqing Li | Hengxian Cui | Yang Li | Qi Li | Q. Yin | Xin Chu | Qifei Cong | Anran Huo | Lu Chen | Jiali Wang | Yuan Qin | Y. Qi
[1] A. Philippides,et al. Dual role of brain endothelial Gpr126 in blood-brain barrier development and ischemic stroke , 2022, bioRxiv.
[2] R. Hall,et al. Adhesion G Protein-Coupled Receptors: Structure, Signaling, Physiology and Pathophysiology. , 2022, Physiological reviews.
[3] Chuan Wang,et al. Progesterone activates GPR126 to promote breast cancer development via the Gi pathway , 2022, Proceedings of the National Academy of Sciences of the United States of America.
[4] D. Stainier,et al. Adhesion G protein–coupled receptor Gpr126/Adgrg6 is essential for placental development , 2021, Science advances.
[5] J. Snedeker,et al. An adhesion G protein-coupled receptor is required in cartilaginous and dense connective tissues to maintain spine alignment , 2021, eLife.
[6] G. Ladds,et al. Emerging roles of adhesion G protein-coupled receptors , 2021, Biochemical Society transactions.
[7] M. Zhong,et al. GPR126 regulates colorectal cancer cell proliferation by mediating HDAC2 and GLI2 expression , 2021, Cancer science.
[8] H. Xu,et al. Structures of the glucocorticoid-bound adhesion receptor GPR97–Go complex , 2021, Nature.
[9] Yi Jiang,et al. Structures of the glucocorticoid-bound adhesion receptor GPR97–Go complex , 2021, Nature.
[10] Y. Allory,et al. Genomic Instability Signature of Palindromic Non-Coding Somatic Mutations in Bladder Cancer , 2020, Cancers.
[11] G. Tall,et al. Mechanisms of adhesion G protein–coupled receptor activation , 2020, The Journal of Biological Chemistry.
[12] Jian Luo,et al. Regulation of body length and bone mass by Gpr126/Adgrg6 , 2020, Science Advances.
[13] K. Monk,et al. Gpr126/Adgrg6 contributes to the terminal Schwann cell response at the neuromuscular junction following peripheral nerve injury , 2019, Glia.
[14] A. Hartmann,et al. Gpr126 (Adgrg6) is expressed in cell types known to be exposed to mechanical stimuli , 2019, Annals of the New York Academy of Sciences.
[15] Joshua A. Riback,et al. Structural basis for adhesion G protein-coupled receptor Gpr126 function , 2019, Nature Communications.
[16] N. Ahituv,et al. Dysregulation of STAT3 signaling is associated with endplate-oriented herniations of the intervertebral disc in Adgrg6 mutant mice , 2019, PLoS genetics.
[17] F. Bassilana,et al. Adhesion G protein-coupled receptors: opportunities for drug discovery , 2019, Nature Reviews Drug Discovery.
[18] Stefanie Giera,et al. Adhesion G Protein-Coupled Receptors as Drug Targets for Neurological Diseases. , 2019, Trends in pharmacological sciences.
[19] Z. Cai,et al. Whole-genome sequencing identifies ADGRG6 enhancer mutations and FRS2 duplications as angiogenesis-related drivers in bladder cancer , 2019, Nature Communications.
[20] Xuhui Zhou,et al. A Genetic Variant in GPR126 Causing a Decreased Inclusion of Exon 6 Is Associated with Cartilage Development in Adolescent Idiopathic Scoliosis Population , 2019, BioMed research international.
[21] Y. Allory,et al. High Prevalence of a Hotspot of Noncoding Somatic Mutations in Intron 6 of GPR126 in Bladder Cancer , 2018, Molecular Cancer Research.
[22] J. Kere,et al. A multi-ethnic meta-analysis confirms the association of rs6570507 with adolescent idiopathic scoliosis , 2018, Scientific Reports.
[23] N. Chen,et al. Myelin injury in the central nervous system and Alzheimer’s disease , 2018, Brain Research Bulletin.
[24] G. Storm,et al. Integrins in wound healing, fibrosis and tumor stroma: High potential targets for therapeutics and drug delivery , 2018, Advanced drug delivery reviews.
[25] H. Arshad,et al. The function of the cellular prion protein in health and disease , 2018, Acta Neuropathologica.
[26] Zhihong Wu,et al. Genetic polymorphisms of GPR126 are functionally associated with PUMC classifications of adolescent idiopathic scoliosis in a Northern Han population , 2018, Journal of cellular and molecular medicine.
[27] B. Hudson,et al. Building collagen IV smart scaffolds on the outside of cells , 2017, Protein science : a publication of the Protein Society.
[28] K. Nave,et al. Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination , 2017, PLoS biology.
[29] A. Castle,et al. Physiological Functions of the Cellular Prion Protein , 2017, Front. Mol. Biosci..
[30] X. Piao,et al. Adhesion G‐protein coupled receptors and extracellular matrix proteins: Roles in myelination and glial cell development , 2017, Developmental dynamics : an official publication of the American Association of Anatomists.
[31] Y. Qiu,et al. Genetic variant of BNC2 gene is functionally associated with adolescent idiopathic scoliosis in Chinese population , 2017, Molecular Genetics and Genomics.
[32] K. Monk,et al. Advances in myelinating glial cell development , 2017, Current Opinion in Neurobiology.
[33] Q. T. Nguyen,et al. Effects of Inflammation on Multiscale Biomechanical Properties of Cartilaginous Cells and Tissues , 2017, ACS biomaterials science & engineering.
[34] U. Suter,et al. Gpr126/Adgrg6 Has Schwann Cell Autonomous and Nonautonomous Functions in Peripheral Nerve Injury and Repair , 2016, The Journal of Neuroscience.
[35] A. Wojtovich,et al. Dihydromunduletone Is a Small-Molecule Selective Adhesion G Protein–Coupled Receptor Antagonist , 2016, Molecular Pharmacology.
[36] S. Hornemann,et al. The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6 , 2016, Nature.
[37] E. Hughes,et al. The cell biology of CNS myelination , 2016, Current Opinion in Neurobiology.
[38] T. Langenhan,et al. Adhesion G protein-coupled receptors in nervous system development and disease , 2016, Nature Reviews Neuroscience.
[39] David C. Jones,et al. Landscape of somatic mutations in 560 breast cancer whole genome sequences , 2016, Nature.
[40] Ruogang Zhao,et al. YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells , 2016, Nature Neuroscience.
[41] P. Bonaldo,et al. Role of macrophages in Wallerian degeneration and axonal regeneration after peripheral nerve injury , 2015, Acta Neuropathologica.
[42] Courtney M. Karner,et al. Gpr126/Adgrg6 deletion in cartilage models idiopathic scoliosis and pectus excavatum in mice. , 2015, Human molecular genetics.
[43] P. Bonaldo,et al. The Role of Collagens in Peripheral Nerve Myelination and Function , 2015, Molecular Neurobiology.
[44] Mathew W. Wright,et al. International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein–Coupled Receptors , 2015, Pharmacological Reviews.
[45] T. Schöneberg,et al. The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211 , 2015, Neuron.
[46] Y. Qiu,et al. Current progress in genetic research of adolescent idiopathic scoliosis. , 2015, Annals of translational medicine.
[47] Q. Bi,et al. Association of GPR126 gene polymorphism with adolescent idiopathic scoliosis in Chinese populations. , 2015, Genomics.
[48] T. Schöneberg,et al. A tethered agonist within the ectodomain activates the adhesion G protein-coupled receptors GPR126 and GPR133. , 2014, Cell reports.
[49] Klaus-Armin Nave,et al. Myelination of the nervous system: mechanisms and functions. , 2014, Annual review of cell and developmental biology.
[50] Mingyao Liu,et al. GPR126 Protein Regulates Developmental and Pathological Angiogenesis through Modulation of VEGFR2 Receptor Signaling* , 2014, The Journal of Biological Chemistry.
[51] W. Talbot,et al. Type IV collagen is an activating ligand for the adhesion G protein–coupled receptor GPR126 , 2014, Science Signaling.
[52] K. Monk,et al. The multiple signaling modalities of adhesion G protein-coupled receptor GPR126 in development. , 2014, Receptors & clinical investigation.
[53] A. Diantonio,et al. Dynamic regulation of SCG10 in regenerating axons after injury , 2014, Experimental Neurology.
[54] T. Schöneberg,et al. Gpr126 Functions in Schwann Cells to Control Differentiation and Myelination via G-Protein Activation , 2013, The Journal of Neuroscience.
[55] K. Monk,et al. Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent , 2013, Proceedings of the National Academy of Sciences.
[56] W. Talbot,et al. Analysis of Gpr126 function defines distinct mechanisms controlling the initiation and maturation of myelin , 2013, Development.
[57] Todd A. Johnson,et al. Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis , 2013, Nature Genetics.
[58] K. Sekiguchi,et al. Schwann cell myelination requires integration of laminin activities , 2012, Journal of Cell Science.
[59] Jens Frahm,et al. Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity , 2012, Nature.
[60] W. Talbot,et al. Gpr126 is essential for peripheral nerve development and myelination in mammals , 2011, Development.
[61] S. Lehoux,et al. Characterization of the Differential Response of Endothelial Cells Exposed to Normal and Elevated Laminar Shear Stress , 2011, Journal of cellular physiology.
[62] T. Langenhan,et al. The Orphan Adhesion-GPCR GPR126 Is Required for Embryonic Development in the Mouse , 2010, PloS one.
[63] Frank Baumann,et al. Axonal prion protein is required for peripheral myelin maintenance , 2010, Nature Neuroscience.
[64] W. Talbot,et al. A G Protein–Coupled Receptor Is Essential for Schwann Cells to Initiate Myelination , 2009, Science.
[65] Y. Qiu,et al. Promoter polymorphism of matrilin-1 gene predisposes to adolescent idiopathic scoliosis in a Chinese population , 2009, European Journal of Human Genetics.
[66] Inês Barroso,et al. Meta-Analysis of Genome-Wide Scans for Human Adult Stature Identifies Novel Loci and Associations with Measures of Skeletal Frame Size , 2009, PLoS genetics.
[67] D. Carey,et al. Regulation of Schwann cell function by the extracellular matrix , 2008, Glia.
[68] Zhihong Wu,et al. Association Study of Tryptophan Hydroxylase 1 and Arylalkylamine N-Acetyltransferase Polymorphisms With Adolescent Idiopathic Scoliosis in Han Chinese , 2008, Spine.
[69] L. Qin,et al. Melatonin Receptor 1B (MTNR1B) Gene Polymorphism Is Associated With the Occurrence of Adolescent Idiopathic Scoliosis , 2007, Spine.
[70] H. Schiöth,et al. Identification of novel splice variants of Adhesion G protein-coupled receptors. , 2007, Gene.
[71] Qiang Sun,et al. Association of Estrogen Receptor Gene Polymorphisms With Susceptibility to Adolescent Idiopathic Scoliosis , 2006, Spine.
[72] Erik Ulfhammer,et al. Differential Global Gene Expression Response Patterns of Human Endothelium Exposed to Shear Stress and Intraluminal Pressure , 2005, Journal of Vascular Research.
[73] L. Wrabetz,et al. Laminins and their receptors in Schwann cells and hereditary neuropathies , 2005, Journal of the peripheral nervous system : JPNS.
[74] B. Binder,et al. VIGR – a novel inducible adhesion family G‐protein coupled receptor in endothelial cells , 2004, FEBS letters.
[75] Troels Z. Kristiansen,et al. A Proteomic Analysis of Human Bile* , 2004, Molecular & Cellular Proteomics.
[76] T. Akiyama,et al. DREG, a developmentally regulated G protein‐coupled receptor containing two conserved proteolytic cleavage sites , 2004, Genes to cells : devoted to molecular & cellular mechanisms.
[77] R. Kalluri. Basement membranes: structure, assembly and role in tumour angiogenesis , 2003, Nature reviews. Cancer.
[78] David E. Gloriam,et al. There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini. , 2003, Biochemical and biophysical research communications.
[79] R. Fields,et al. New insights into neuron-glia communication. , 2002, Science.
[80] Jingsong Xu,et al. Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo , 2001, The Journal of cell biology.
[81] W. O'Fallon,et al. Ischemic stroke , 1998, Neurology.
[82] R. Bunge,et al. Linkage between Schwann Cell Extracellular Matrix Production and Ensheathment Function a , 1986, Annals of the New York Academy of Sciences.
[83] J. Leong,et al. Ultrastructures of nerve fibers and muscle spindles in adolescent idiopathic scoliosis. , 1983, Clinical orthopaedics and related research.
[84] Peter D Yurchenco,et al. Basement membrane assembly, stability and activities observed through a developmental lens. , 2004, Matrix Biology.