Partial restoration of all trans retinoic acid (ATRA) sensitivity by compactin in ATRA-resistant leukemic cells (ATRA-R HL-60).

[1]  N. Gueddari,et al.  Enhancement of all-trans-retinoic acid efficiency in granulocytic differentiation of HL-60 cells by incorporation into low density lipoprotein. , 1998, International Journal of Oncology.

[2]  H. Koeffler,et al.  Mechanisms of retinoid resistance in leukemic cells: possible role of cytochrome P450 and P-glycoprotein. , 1996, Blood.

[3]  H. Koeffler,et al.  Effects of novel retinoic acid compound, 9-cis-retinoic acid, on proliferation, differentiation, and expression of retinoic acid receptor-alpha and retinoid X receptor-alpha RNA by HL-60 cells. , 1993, Blood.

[4]  H. Tilly,et al.  Effectiveness and pharmacokinetics of low-dose all-trans retinoic acid (25 mg/m2) in acute promyelocytic leukemia , 1993 .

[5]  R. Warrell Retinoid resistance in acute promyelocytic leukemia: new mechanisms, strategies, and implications. , 1993, Blood.

[6]  G. Favre,et al.  Low density lipoprotein for cytotoxic drug targeting: improved activity of elliptinium derivative against B16 melanoma in mice. , 1993, British Journal of Cancer.

[7]  R. Warrell,et al.  Acute promyelocytic leukemia. , 1993, The New England journal of medicine.

[8]  J. Fruchart,et al.  Sequential ultracentrifugation micromethod for separation of serum lipoproteins and assays of lipids, apolipoproteins, and lipoprotein particles. , 1993, Clinical chemistry.

[9]  M. Andreeff,et al.  Induction of differentiation in myeloid leukemia cell lines and acute promyelocytic leukemia cells by liposomal all-trans-retinoic acid. , 1993, Cancer research.

[10]  R. Warrell,et al.  Clinical pharmacology of oral all-trans retinoic acid in patients with acute promyelocytic leukemia. , 1992, Cancer research.

[11]  R. Gadde,et al.  Simple reversed-phase high-performance liquid chromatographic method for 13-cis-retinoic acid in serum. , 1992, Journal of chromatography.

[12]  E. Dmitrovsky,et al.  Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations: implications for relapse and retinoid "resistance" in patients with acute promyelocytic leukemia. , 1992, Blood.

[13]  Zi X. Chen,et al.  A clinical and experimental study on all-trans retinoic acid-treated acute promyelocytic leukemia patients. , 1991, Blood.

[14]  E. Dmitrovsky,et al.  Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid). , 1991, The New England journal of medicine.

[15]  L. Gudas,et al.  Overexpression of the cellular retinoic acid binding protein-I (CRABP- I) results in a reduction in differentiation-specific gene expression in F9 teratocarcinoma cells , 1991, The Journal of cell biology.

[16]  M. Pratt,et al.  A dominant negative mutation of the alpha retinoic acid receptor gene in a retinoic acid-nonresponsive embryonal carcinoma cell , 1990, Molecular and cellular biology.

[17]  R Berger,et al.  All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results. , 1990, Blood.

[18]  R. Evans,et al.  Nuclear receptor that identifies a novel retinoic acid response pathway , 1990, Nature.

[19]  S. Collins,et al.  Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-alpha) , 1990, Molecular and cellular biology.

[20]  J. Goldstein,et al.  Regulation of the mevalonate pathway , 1990, Nature.

[21]  Zhen-yi Wang,et al.  Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. , 1988, Haematology and blood transfusion.

[22]  R. Evans,et al.  The steroid and thyroid hormone receptor superfamily. , 1988, Science.

[23]  Pierre Chambon,et al.  A human retinoic acid receptor which belongs to the family of nuclear receptors , 1987, Nature.

[24]  V. Giguère,et al.  Identification of a receptor for the morphogen retinoic acid , 1987, Nature.

[25]  S. Collins,et al.  Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxide , 1979, The Journal of experimental medicine.

[26]  M. Brown,et al.  Binding, internalization, and hydrolysis of low density lipoprotein in long-term lymphoid cell lines from a normal subject and a patient with homozygous familial hypercholesterolemia , 1976, The Journal of experimental medicine.

[27]  T. Leemann,et al.  In vitro comparative inhibition profiles of major human drug metabolising cytochrome P450 isozymes (CYP2C9, CYP2D6 and CYP3A4) by HMG-CoA reductase inhibitors , 1996, European Journal of Clinical Pharmacology.

[28]  G. Favre,et al.  Evidence for up-regulated low density lipoprotein receptor in human lung adenocarcinoma cell line A549. , 1993, Biochimie.