CD4-mediated regulatory T-cell activation inhibits the development of disease in a humanized mouse model of allergic airway disease.

[1]  Y. Hsu,et al.  Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma. , 2010, The Journal of clinical investigation.

[2]  F. Spertini,et al.  CD4+CD25+ T cell depletion impairs tolerance induction in a murine model of asthma , 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[3]  Sebastian Reuter,et al.  Protection from graft-versus-host disease by HIV-1 envelope protein gp120-mediated activation of human CD4+CD25+ regulatory T cells. , 2009, Blood.

[4]  S. Sakaguchi,et al.  Therapeutic approaches to allergy and autoimmunity based on FoxP3+ regulatory T-cell activation and expansion. , 2009, The Journal of allergy and clinical immunology.

[5]  R. Andreesen,et al.  Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation , 2009, European journal of immunology.

[6]  H. Schild,et al.  Inhibition of cAMP Degradation Improves Regulatory T Cell-Mediated Suppression1 , 2009, The Journal of Immunology.

[7]  M. Cloyd,et al.  HIV-1 binding to CD4 on CD4+CD25+ regulatory T cells enhances their suppressive function and induces them to home to, and accumulate in, peripheral and mucosal lymphoid tissues: an additional mechanism of immunosuppression. , 2009, International immunology.

[8]  Liguo Zhang,et al.  FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2-/-gammaC-/- mice in vivo. , 2008, Blood.

[9]  D. Robinson,et al.  CD4+CD25+ regulatory T cells reverse established allergic airway inflammation and prevent airway remodeling. , 2008, The Journal of allergy and clinical immunology.

[10]  S. Reuter,et al.  Mast cell-derived tumour necrosis factor is essential for allergic airway disease , 2008, European Respiratory Journal.

[11]  R. Woodland,et al.  A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene. , 2008, Clinical immunology.

[12]  C. Shieh,et al.  The functional insufficiency of human CD4+CD25high T‐regulatory cells in allergic asthma is subjected to TNF‐α modulation , 2007, Allergy.

[13]  C. Akdis,et al.  Immune regulation by CD4+CD25+ T cells and interleukin‐10 in birch pollen‐allergic patients and non‐allergic controls , 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[14]  H. Schild,et al.  Cyclic adenosine monophosphate is a key component of regulatory T cell–mediated suppression , 2007, The Journal of experimental medicine.

[15]  J. Wijdenes,et al.  CD4‐mediated functional activation of human CD4+CD25+ regulatory T cells , 2007, European Journal of Immunology.

[16]  E. Gelfand,et al.  Erratum: Naturally occurring lung CD4+CD25+ T cell regulation of airway allergic responses depends on IL-10 induction of TGF-β (Journal of Immunology (2007) 178 (1433-1442)) , 2007 .

[17]  M. Roncarolo,et al.  Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production. , 2007, International immunology.

[18]  A. Fauci,et al.  Suppression of HIV-specific T cell activity by lymph node CD25+ regulatory T cells from HIV-infected individuals , 2007, Proceedings of the National Academy of Sciences.

[19]  E. Gelfand,et al.  Naturally Occurring Lung CD4+CD25+ T Cell Regulation of Airway Allergic Responses Depends on IL-10 Induction of TGF-β1 , 2007, The Journal of Immunology.

[20]  C. Chougnet,et al.  HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS. , 2006, Blood.

[21]  D. Robinson,et al.  Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4+CD25+ regulatory T cells is interleukin 10 dependent , 2005, The Journal of experimental medicine.

[22]  Y. Belkaid,et al.  CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function , 2005, The Journal of experimental medicine.

[23]  M. Kotb,et al.  Human Lymphoid and Myeloid Cell Development in NOD/LtSz-scid IL2Rγnull Mice Engrafted with Mobilized Human Hemopoietic Stem Cells 12 , 2004, The Journal of Immunology.

[24]  C. Akdis,et al.  Immune Responses in Healthy and Allergic Individuals Are Characterized by a Fine Balance between Allergen-specific T Regulatory 1 and T Helper 2 Cells , 2004, The Journal of experimental medicine.

[25]  R. Paus,et al.  Increased airway responsiveness, allergy‐type‐I skin responses and systemic anaphylaxis in a humanized‐severe combined immuno‐deficiency mouse model , 2004, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[26]  M. Dallman,et al.  Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease , 2004, The Lancet.

[27]  A. Knulst,et al.  CD4 CD25 regulatory T cells are not functionally impaired in adult patients with IgE-mediated cow's milk allergy. , 2002, The Journal of allergy and clinical immunology.

[28]  G. Freeman,et al.  CD4+CD25high Regulatory Cells in Human Peripheral Blood1 , 2001, The Journal of Immunology.

[29]  Steinsvik,et al.  Interleukin‐13 and Human Immunoglobulin E Production in Severe Combined Immunodeficiency Mice Transplanted with Human Peripheral Blood Lymphocytes , 1999, Scandinavian journal of immunology.

[30]  U. Wahn,et al.  A human-SCID mouse model for allergic immune response bacterial superantigen enhances skin inflammation and suppresses IgE production. , 1998, The Journal of investigative dermatology.

[31]  J. Hébert,et al.  Lol p I-specific IgE and IgG synthesis by peripheral blood mononuclear cells from atopic subjects in SCID mice. , 1995, The Journal of allergy and clinical immunology.

[32]  M. S. Huang,et al.  Establishment of human IgE system in severe combined immunodeficient mice with peripheral blood mononuclear cells from asthmatic children. , 1995, The Journal of allergy and clinical immunology.

[33]  A. Fischer,et al.  Human immunodeficiency virus gp120 and derived peptides activate protein tyrosine kinase p56Ick in human CD4 T lymphocytes , 1993, European journal of immunology.

[34]  D. Kioussis,et al.  "Infectious" transplantation tolerance , 1993, Science.