AMPK: Sensing Glucose as well as Cellular Energy Status.

[1]  M. Erion,et al.  Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy , 2017, Science.

[2]  G. Steinberg,et al.  AMPK as a Therapeutic Target for Treating Metabolic Diseases , 2017, Trends in Endocrinology & Metabolism.

[3]  F. Ross,et al.  Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib , 2017, Cell chemical biology.

[4]  Robin J. W. Willows,et al.  Phosphorylation of AMPK by upstream kinases is required for activity in mammalian cells , 2017, The Biochemical journal.

[5]  Sheng-Cai Lin,et al.  Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK , 2017, Nature.

[6]  R. Shaw,et al.  AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance. , 2017, Molecular cell.

[7]  P. Griffin,et al.  Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing , 2017, The Journal of Biological Chemistry.

[8]  M. Llinás,et al.  Nutrient sensing modulates malaria parasite virulence , 2017, Nature.

[9]  B. Viollet,et al.  Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice. , 2017, Cell metabolism.

[10]  Robin J. W. Willows,et al.  Effect of different γ-subunit isoforms on the regulation of AMPK , 2017, The Biochemical journal.

[11]  David M. Sabatini,et al.  mTOR Signaling in Growth, Metabolism, and Disease , 2017, Cell.

[12]  M. Berriman,et al.  Complete avian malaria parasite genomes reveal host-specific parasite evolution in birds and mammals , 2016, bioRxiv.

[13]  Chen-Song Zhang,et al.  Metformin Activates AMPK through the Lysosomal Pathway. , 2016, Cell metabolism.

[14]  R. Zoncu,et al.  Author response: Dynamics of mTORC1 activation in response to amino acids , 2016 .

[15]  D. Hardie,et al.  AMP‐activated protein kinase: a cellular energy sensor that comes in 12 flavours , 2016, The FEBS journal.

[16]  A. Brunet,et al.  AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs. , 2016, Trends in cell biology.

[17]  F. Polleux,et al.  AMP-activated protein kinase mediates mitochondrial fission in response to energy stress , 2016, Science.

[18]  F. Ross,et al.  Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms , 2015, The Biochemical journal.

[19]  Jianping Ding,et al.  Crystal structure of the Ego1-Ego2-Ego3 complex and its role in promoting Rag GTPase-dependent TORC1 signaling , 2015, Cell Research.

[20]  H. Xu,et al.  Structural basis of AMPK regulation by adenine nucleotides and glycogen , 2014, Cell Research.

[21]  B. Kemp,et al.  Choreography of AMPK activation , 2014, Cell Research.

[22]  Jianping Ding,et al.  Crystal structure of the Ego 1-Ego 2-Ego 3 complex and its role in promoting Rag GTPase-dependent TORC 1 signaling , 2015 .

[23]  Jiahuai Han,et al.  The lysosomal v-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism. , 2014, Cell metabolism.

[24]  R. Kurumbail,et al.  Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms. , 2014, Structure.

[25]  A Keith Dunker,et al.  Intrinsically disordered proteins and intrinsically disordered protein regions. , 2014, Annual review of biochemistry.

[26]  J. Rubinstein,et al.  Eukaryotic V-ATPase: novel structural findings and functional insights. , 2014, Biochimica et biophysica acta.

[27]  B. Kemp,et al.  Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling. , 2014, Chemistry & biology.

[28]  Américo Rodrigues,et al.  Mechanisms of regulation of SNF1/AMPK/SnRK1 protein kinases , 2014, Front. Plant Sci..

[29]  F. Ross,et al.  Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells , 2014, The Biochemical journal.

[30]  D. Alessi,et al.  Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity , 2013, The Biochemical journal.

[31]  David Carling,et al.  Structural basis of AMPK regulation by small molecule activators , 2013, Nature Communications.

[32]  D. Hardie,et al.  AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation , 2013, Cell metabolism.

[33]  D. Hardie,et al.  AMPK: mediating the metabolic effects of salicylate-based drugs? , 2013, Trends in Endocrinology & Metabolism.

[34]  Jiahuai Han,et al.  AMP as a low-energy charge signal autonomously initiates assembly of AXIN-AMPK-LKB1 complex for AMPK activation. , 2013, Cell metabolism.

[35]  H. Watkins,et al.  Localisation of AMPK γ subunits in cardiac and skeletal muscles , 2013, Journal of Muscle Research and Cell Motility.

[36]  Zhi-Xin Wang,et al.  Coordinated regulation of AMPK activity by multiple elements in the α-subunit , 2013, Cell Research.

[37]  Zhi-Xin Wang,et al.  Conserved regulatory elements in AMPK , 2013, Nature.

[38]  Jiandie D. Lin,et al.  Inhibition of AMPK catabolic action by GSK3. , 2013, Molecular cell.

[39]  O. Kirak,et al.  Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival , 2012, Nature.

[40]  D. Sabatini,et al.  Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1 , 2012, Cell.

[41]  G. Barton,et al.  The kinomes of apicomplexan parasites. , 2012, Microbes and infection.

[42]  Zhi-Xin Wang,et al.  AMP-activated protein kinase undergoes nucleotide-dependent conformational changes , 2012, Nature Structural &Molecular Biology.

[43]  B. Kemp,et al.  The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase , 2012, Science.

[44]  B. Viollet,et al.  AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase. , 2012, The Biochemical journal.

[45]  David Carling,et al.  ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase , 2011, Cell metabolism.

[46]  Roberto Zoncu,et al.  mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase , 2011, Science.

[47]  B. Kemp,et al.  AMPK Is a Direct Adenylate Charge-Regulated Protein Kinase , 2011, Science.

[48]  David Carling,et al.  Structure of Mammalian AMPK and its regulation by ADP , 2011, Nature.

[49]  Susan S. Taylor,et al.  Protein kinases: evolution of dynamic regulatory proteins. , 2011, Trends in biochemical sciences.

[50]  B. Viollet,et al.  Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy , 2011, Science.

[51]  D. Sabatini,et al.  mTORC 1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H +-ATPase , 2011 .

[52]  B. Kemp,et al.  β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK) , 2010, Proceedings of the National Academy of Sciences.

[53]  Alex Bateman,et al.  The Systematic Functional Analysis of Plasmodium Protein Kinases Identifies Essential Regulators of Mosquito Transmission , 2010, Cell host & microbe.

[54]  T. Williams,et al.  Identification of a Nuclear Export Signal in the Catalytic Subunit of AMP-activated Protein Kinase , 2010, Molecular biology of the cell.

[55]  F. Ross,et al.  Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation , 2010, Cell metabolism.

[56]  B. Viollet,et al.  Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner. , 2010, Cell metabolism.

[57]  D. Sabatini,et al.  Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids , 2010, Cell.

[58]  F. Ross,et al.  Use of Cells Expressing gamma Subunit Variants to Identify Diverse Mechanisms of AMPK Activation , 2010 .

[59]  Zhi-Xin Wang,et al.  Structural insight into the autoinhibition mechanism of AMP-activated protein kinase , 2009, Nature.

[60]  S. Ryu,et al.  Glycolytic Flux Signals to mTOR through Glyceraldehyde-3-Phosphate Dehydrogenase-Mediated Regulation of Rheb , 2009, Molecular and Cellular Biology.

[61]  M. Foretz,et al.  AMP-activated Protein Kinase Phosphorylates R5/PTG, the Glycogen Targeting Subunit of the R5/PTG-Protein Phosphatase 1 Holoenzyme, and Accelerates Its Down-regulation by the Laforin-Malin Complex* , 2009, Journal of Biological Chemistry.

[62]  M. Okada,et al.  The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK–ERK pathway to late endosomes , 2009, The EMBO journal.

[63]  D. Hardie,et al.  Edinburgh Research Explorer The glycogen-binding domain on the AMPK beta subunit allows the kinase to act as a glycogen sensor , 2008 .

[64]  A. Rufer,et al.  Structural Properties of AMP-activated Protein Kinase , 2008, Journal of Biological Chemistry.

[65]  David M. Sabatini,et al.  The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1 , 2008, Science.

[66]  Anastasios D. Tsaousis,et al.  A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi , 2008, Nature.

[67]  B. Turk,et al.  AMPK phosphorylation of raptor mediates a metabolic checkpoint. , 2008, Molecular cell.

[68]  P. Keeling,et al.  Distinct Localization Patterns of Two Putative Mitochondrial Proteins in the Microsporidian Encephalitozoon cuniculi , 2008, The Journal of eukaryotic microbiology.

[69]  Karen M. Arndt,et al.  Access Denied: Snf1 Activation Loop Phosphorylation Is Controlled by Availability of the Phosphorylated Threonine 210 to the PP1 Phosphatase* , 2008, Journal of Biological Chemistry.

[70]  B. Viollet,et al.  Mechanism of Action of A-769662, a Valuable Tool for Activation of AMP-activated Protein Kinase* , 2007, Journal of Biological Chemistry.

[71]  R. Heath,et al.  Defining the Mechanism of Activation of AMP-activated Protein Kinase by the Small Molecule A-769662, a Member of the Thienopyridone Family* , 2007, Journal of Biological Chemistry.

[72]  B. Kemp,et al.  AMPK structure and regulation from three angles. , 2007, Structure.

[73]  David Carling,et al.  Structural basis for AMP binding to mammalian AMP-activated protein kinase , 2007, Nature.

[74]  G. Barton,et al.  The complement of protein kinases of the microsporidium Encephalitozoon cuniculi in relation to those of Saccharomyces cerevisiae and Schizosaccharomyces pombe , 2007, BMC Genomics.

[75]  M. Lu,et al.  Physical Interaction between Aldolase and Vacuolar H+-ATPase Is Essential for the Assembly and Activity of the Proton Pump* , 2007, Journal of Biological Chemistry.

[76]  Jun Ren,et al.  Ca2+/calmodulin‐dependent protein kinase kinases are mainly responsible for AMP‐activated protein kinase activation by α‐ lipoic acid in C2C12 myotubes , 2007 .

[77]  D. Carling,et al.  Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade. , 2007, The Biochemical journal.

[78]  Tao Pang,et al.  Conserved α-Helix Acts as Autoinhibitory Sequence in AMP-activated Protein Kinase α Subunits* , 2007, Journal of Biological Chemistry.

[79]  Karen M. Arndt,et al.  Snf 1 Activation Loop Phosphorylation Is Controlled by Availability of the Phosphorylated Threonine 210 to the PP 1 Phosphatase * , 2007 .

[80]  A. Means,et al.  Regulation of AMP-activated Protein Kinase by Multisite Phosphorylation in Response to Agents That Elevate Cellular cAMP*> , 2006, Journal of Biological Chemistry.

[81]  Š. Janeček,et al.  The evolution of putative starch‐binding domains , 2006, FEBS letters.

[82]  L. Kifle,et al.  Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome. , 2006, Cell metabolism.

[83]  D. Vertommen,et al.  Insulin Antagonizes Ischemia-induced Thr172 Phosphorylation of AMP-activated Protein Kinase α-Subunits in Heart via Hierarchical Phosphorylation of Ser485/491* , 2006, Journal of Biological Chemistry.

[84]  J. Eggermont,et al.  CBS domains: structure, function, and pathology in human proteins. , 2005, American journal of physiology. Cell physiology.

[85]  Galina Polekhina,et al.  Structural basis for glycogen recognition by AMP-activated protein kinase. , 2005, Structure.

[86]  R. Heath,et al.  Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. , 2005, Cell metabolism.

[87]  A. Edelman,et al.  Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. , 2005, Cell metabolism.

[88]  Sheng-Cai Lin,et al.  Axin Contains Three Separable Domains That Confer Intramolecular, Homodimeric, and Heterodimeric Interactions Involved in Distinct Functions* , 2005, Journal of Biological Chemistry.

[89]  B. Viollet,et al.  The alpha2-5'AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading. , 2004, Diabetes.

[90]  H. Ronne,et al.  Snf1‐related protein kinase 1 is needed for growth in a normal day–night light cycle , 2004, The EMBO journal.

[91]  Lewis C Cantley,et al.  The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[92]  M. Lu,et al.  The Glycolytic Enzyme Aldolase Mediates Assembly, Expression, and Activity of Vacuolar H+-ATPase* , 2004, Journal of Biological Chemistry.

[93]  D. Hardie,et al.  CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations. , 2004, The Journal of clinical investigation.

[94]  M. Ciriacy.  Isolation and characterization of yeast mutants defective in intermediary carbon metabolism and in carbon catabolite derepression , 1977, Molecular and General Genetics MGG.

[95]  F. Zimmermann,et al.  Genetics of carbon catabolite repression in Saccharomyces cerevisiae: genes involved in the derepression process , 1977, Molecular and General Genetics MGG.

[96]  K. Inoki,et al.  TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival , 2003, Cell.

[97]  H. Boucherie,et al.  The Snf1 Protein Kinase Controls the Induction of Genes of the Iron Uptake Pathway at the Diauxic Shift in Saccharomyces cerevisiae* , 2003, Journal of Biological Chemistry.

[98]  David Carling,et al.  Supplemental Data LKB 1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade , 2003 .

[99]  Jérôme Boudeau,et al.  Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade , 2003, Journal of biology.

[100]  B. Kemp,et al.  AMPK β Subunit Targets Metabolic Stress Sensing to Glycogen , 2003, Current Biology.

[101]  J. James,et al.  A Novel Domain in AMP-Activated Protein Kinase Causes Glycogen Storage Bodies Similar to Those Seen in Hereditary Cardiac Arrhythmias , 2003, Current Biology.

[102]  B. Kemp,et al.  AMPK beta subunit targets metabolic stress sensing to glycogen. , 2003, Current biology : CB.

[103]  G. Shulman,et al.  AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[104]  D. Hardie,et al.  AMP‐activated protein kinase: the energy charge hypothesis revisited , 2001, BioEssays : news and reviews in molecular, cellular and developmental biology.

[105]  Fabienne Thomarat,et al.  Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi , 2001, Nature.

[106]  M. Lu,et al.  Interaction between Aldolase and Vacuolar H+-ATPase , 2001, The Journal of Biological Chemistry.

[107]  R. McCartney,et al.  β‐subunits of Snf1 kinase are required for kinase function and substrate definition , 2000, The EMBO journal.

[108]  D. Carling,et al.  Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding. , 2000, The Biochemical journal.

[109]  D. Hardie,et al.  Regulation of spinach SNF1-related (SnRK1) kinases by protein kinases and phosphatases is associated with phosphorylation of the T loop and is regulated by 5'-AMP. , 1999, The Plant journal : for cell and molecular biology.

[110]  D. Hardie,et al.  AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge. , 1999, The Biochemical journal.

[111]  B. Kemp,et al.  Functional Domains of the α1 Catalytic Subunit of the AMP-activated Protein Kinase* , 1998, The Journal of Biological Chemistry.

[112]  D. Hardie,et al.  AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells, and may regulate insulin release. , 1998, The Biochemical journal.

[113]  A. Prescott,et al.  AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform. , 1998, The Biochemical journal.

[114]  C. Thornton,et al.  Identification of a Novel AMP-activated Protein Kinase β Subunit Isoform That Is Highly Expressed in Skeletal Muscle* , 1998, The Journal of Biological Chemistry.

[115]  M. Carlson,et al.  The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell? , 1998, Annual review of biochemistry.

[116]  A. Prescott,et al.  AMP-activated protein kinase : greater AMP dependence , and preferential nuclear localization , of complexes containing the α 2 isoform , 1998 .

[117]  B. Kemp,et al.  Posttranslational Modifications of the 5′-AMP-activated Protein Kinase β1 Subunit* , 1997, The Journal of Biological Chemistry.

[118]  Wei Hsu,et al.  The Mouse Fused Locus Encodes Axin, an Inhibitor of the Wnt Signaling Pathway That Regulates Embryonic Axis Formation , 1997, Cell.

[119]  The AMP‐Activated Protein Kinase , 1997 .

[120]  M. Carlson,et al.  The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex , 1997, Molecular and cellular biology.

[121]  A. Bateman.  The structure of a domain common to archaebacteria and the homocystinuria disease protein. , 1997, Trends in biochemical sciences.

[122]  D. Hardie,et al.  Glucose repression/derepression in budding yeast: SNF1 protein kinase is activated by phosphorylation under derepressing conditions, and this correlates with a high AMP:ATP ratio , 1996, Current Biology.

[123]  S. Hawley,et al.  Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase* , 1996, The Journal of Biological Chemistry.

[124]  M. Bolognesi,et al.  The allosteric regulation of pyruvate kinase , 1996, FEBS letters.

[125]  B. Kemp,et al.  Mammalian AMP-activated Protein Kinase Subfamily (*) , 1996, The Journal of Biological Chemistry.

[126]  B. Kemp,et al.  Mammalian 5'-AMP-activated protein kinase non-catalytic subunits are homologs of proteins that interact with yeast Snf1 protein kinase. , 1994, The Journal of biological chemistry.

[127]  J. Scott,et al.  Yeast SNF1 is functionally related to mammalian AMP-activated protein kinase and regulates acetyl-CoA carboxylase in vivo. , 1994, The Journal of biological chemistry.

[128]  A. J. Morris,et al.  Site-directed mutagenesis identifies aspartate 33 as a previously unidentified critical residue in the catalytic mechanism of rabbit aldolase A. , 1993, The Journal of biological chemistry.

[129]  D. Hardie,et al.  Evidence for a protein kinase cascade in higher plants. 3-Hydroxy-3-methylglutaryl-CoA reductase kinase. , 1992, European journal of biochemistry.

[130]  F. Klippel.  Where is the mouse , 1990 .

[131]  M. Carlson,et al.  Molecular analysis of the SNF4 gene of Saccharomyces cerevisiae: evidence for physical association of the SNF4 protein with the SNF1 protein kinase , 1989, Molecular and cellular biology.

[132]  A. Sim,et al.  The AMP-activated protein kinase: a multisubstrate regulator of lipid metabolism , 1989 .

[133]  D. Hardie,et al.  Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase. , 1988, European journal of biochemistry.

[134]  David Carling,et al.  A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis , 1987, FEBS letters.

[135]  M. Carlson,et al.  A yeast gene that is essential for release from glucose repression encodes a protein kinase. , 1986, Science.

[136]  M. Carlson,et al.  Genes affecting the regulation of SUC2 gene expression by glucose repression in Saccharomyces cerevisiae. , 1984, Genetics.

[137]  F. Zimmermann,et al.  New genes involved in carbon catabolite repression and derepression in the yeast Saccharomyces cerevisiae , 1982, Journal of bacteriology.

[138]  D. Botstein,et al.  Mutants of yeast defective in sucrose utilization. , 1981, Genetics.

[139]  K. Kim,et al.  Regulation of rat liver acetyl-CoA carboxylase. Regulation of phosphorylation and inactivation of acetyl-CoA carboxylase by the adenylate energy charge. , 1980, The Journal of biological chemistry.

[140]  R. Parker,et al.  Reversible modulation of the activities of both liver microsomal hydroxymethylglutaryl coenzyme A reductase and its inactivating enzyme. Evidence for regulation by phosphorylation-dephosphorylation. , 1978, Biochemical and biophysical research communications.

[141]  D. Dietzler,et al.  Maintenance of the energy charge in the presence of large decreases in the total adenylate pool of Escherichia coli and concurrent changes in glucose-6-p, fructose-p2 and glycogen synthesis. , 1974, Biochemical and biophysical research communications.

[142]  Z. Beg,et al.  Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP and wth protein fractions of rat liver cytosol. , 1973, Biochemical and biophysical research communications.

[143]  C. Carlson,et al.  Regulation of hepatic acetyl coenzyme A carboxylase by phosphorylation and dephosphorylation. , 1973, The Journal of biological chemistry.

[144]  J. Preiss,et al.  Biosynthesis of bacterial glycogen IX: regulatory properties of the adenosine diphosphate glucose pyrophosphrylases of the Enterobacterieae. , 1971, Archives of biochemistry and biophysics.

[145]  L. Sagan.  On the origin of mitosing cells , 1967, Journal of theoretical biology.

[146]  H. Krebs.  The Croonian Lecture, 1963 Gluconeogenesis , 1964, Proceedings of the Royal Society of London. Series B. Biological Sciences.