The redox mechanism for vascular barrier dysfunction associated with metabolic disorders: Glutathionylation of Rac1 in endothelial cells

[1]  M. Brownlee,et al.  Molecular and Cellular Mechanisms of Cardiovascular Disorders in Diabetes. , 2016, Circulation research.

[2]  J. Beckman,et al.  Vascular Complications of Diabetes. , 2016, Circulation research.

[3]  M. Lindholm,et al.  Altered metabolism of LDL in the arterial wall precedes atherosclerosis regression. , 2015, Circulation research.

[4]  H. Jo,et al.  Mechanosensitive PPAP2B Regulates Endothelial Responses to Atherorelevant Hemodynamic Forces. , 2015, Circulation research.

[5]  B. Olde,et al.  Correction: The ATP Receptors P2X7 and P2X4 Modulate High Glucose and Palmitate-Induced Inflammatory Responses in Endothelial Cells , 2015, PloS one.

[6]  B. Olde,et al.  The ATP Receptors P2X7 and P2X4 Modulate High Glucose and Palmitate-Induced Inflammatory Responses in Endothelial Cells , 2015, PloS one.

[7]  N. Ruderman,et al.  Glucose and palmitate uncouple AMPK from autophagy in human aortic endothelial cells. , 2015, American journal of physiology. Cell physiology.

[8]  Xian Chen,et al.  Redox regulation of Rac1 by thiol oxidation. , 2015, Free radical biology & medicine.

[9]  K. Griendling,et al.  Regulation of Signal Transduction by Reactive Oxygen Species in the Cardiovascular System , 2015, Circulation research.

[10]  D. Popov.  Protein S-glutathionylation: from current basics to targeted modifications , 2014, Archives of physiology and biochemistry.

[11]  J. Zweier,et al.  Hypoxia and Reoxygenation Induce Endothelial Nitric Oxide Synthase Uncoupling in Endothelial Cells through Tetrahydrobiopterin Depletion and S-Glutathionylation , 2014, Biochemistry.

[12]  A. Klip,et al.  Akt and Rac1 signaling are jointly required for insulin-stimulated glucose uptake in skeletal muscle and downregulated in insulin resistance. , 2014, Cellular signalling.

[13]  Jingyan Han,et al.  Glutaredoxin-1 Up-regulation Induces Soluble Vascular Endothelial Growth Factor Receptor 1, Attenuating Post-ischemia Limb Revascularization* , 2014, The Journal of Biological Chemistry.

[14]  Jingyan Han,et al.  A Redox-resistant Sirtuin-1 Mutant Protects against Hepatic Metabolic and Oxidant Stress* , 2014, The Journal of Biological Chemistry.

[15]  Feng Zhang,et al.  Genome engineering using CRISPR-Cas9 system. , 2015, Methods in molecular biology.

[16]  Xin Wang,et al.  Unique catalytic activities and scaffolding of p21 activated kinase-1 in cardiovascular signaling , 2013, Front. Pharmacol..

[17]  Mete Civelek,et al.  The atherosusceptible endothelium: endothelial phenotypes in complex haemodynamic shear stress regions in vivo. , 2013, Cardiovascular research.

[18]  C. Lillig,et al.  Glutaredoxins in thiol/disulfide exchange. , 2013, Antioxidants & redox signaling.

[19]  S. Campbell,et al.  Redox regulation of Ras and Rho GTPases: mechanism and function. , 2013, Antioxidants & redox signaling.

[20]  S. Rohrbach,et al.  Hypoxia–reoxygenation‐induced endothelial barrier failure: role of RhoA, Rac1 and myosin light chain kinase , 2013, The Journal of physiology.

[21]  N. Ruderman,et al.  Protein Kinase C-&bgr; Contributes to Impaired Endothelial Insulin Signaling in Humans With Diabetes Mellitus , 2012, Circulation.

[22]  Seoung Woo Shin,et al.  S-glutathionylation regulates GTP-binding of Rac2. , 2012, Biochemical and biophysical research communications.

[23]  Jun Wang,et al.  Overexpression of actin-depolymerizing factor blocks oxidized low-density lipoprotein-induced mouse brain microvascular endothelial cell barrier dysfunction , 2012, Molecular and Cellular Biochemistry.

[24]  A. Bhatnagar,et al.  Protein S-glutathiolation: redox-sensitive regulation of protein function. , 2012, Journal of molecular and cellular cardiology.

[25]  J. Mieyal,et al.  Posttranslational modification of cysteine in redox signaling and oxidative stress: Focus on s-glutathionylation. , 2012, Antioxidants & redox signaling.

[26]  R. Cohen,et al.  Oxidation of HRas cysteine thiols by metabolic stress prevents palmitoylation in vivo and contributes to endothelial cell apoptosis , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[27]  K. Node,et al.  Endothelial dysfunction as a cellular mechanism for vascular failure. , 2012, American journal of physiology. Heart and circulatory physiology.

[28]  Zhenqi Liu,et al.  Hyperglycemia in apolipoprotein E-deficient mouse strains with different atherosclerosis susceptibility , 2011, Cardiovascular diabetology.

[29]  A. Ryan,et al.  Mitochondrial Rac1 GTPase Import and Electron Transfer from Cytochrome c Are Required for Pulmonary Fibrosis* , 2011, The Journal of Biological Chemistry.

[30]  Cynthia A. Reinhart-King,et al.  Age-Related Intimal Stiffening Enhances Endothelial Permeability and Leukocyte Transmigration , 2011, Science Translational Medicine.

[31]  M. Murakami,et al.  m-Calpain Induction in Vascular Endothelial Cells on Human and Mouse Atheromas and Its Roles in VE-Cadherin Disorganization and Atherosclerosis , 2011, Circulation.

[32]  K. Burridge,et al.  Rho protein crosstalk: another social network? , 2011, Trends in cell biology.

[33]  D. Sedding,et al.  Insulin Stabilizes Microvascular Endothelial Barrier Function via Phosphatidylinositol 3-Kinase/Akt-Mediated Rac1 Activation , 2010, Arteriosclerosis, thrombosis, and vascular biology.

[34]  Ya-ping Zhao,et al.  Mitochondrial dysfunction is induced by high levels of glucose and free fatty acids in 3T3-L1 adipocytes , 2010, Molecular and Cellular Endocrinology.

[35]  N. Sawada,et al.  Novel aspects of the roles of Rac1 GTPase in the cardiovascular system. , 2010, Current opinion in pharmacology.

[36]  A. Birukova,et al.  Rac GTPase is a hub for protein kinase A and Epac signaling in endothelial barrier protection by cAMP. , 2010, Microvascular research.

[37]  V. Zammit,et al.  High glucose and elevated fatty acids suppress signaling by the endothelium protective ligand angiopoietin-1. , 2010, Microvascular research.

[38]  T. Kondo,et al.  Roles of oxidative stress and redox regulation in atherosclerosis. , 2009, Journal of atherosclerosis and thrombosis.

[39]  M. Birnbaum,et al.  Contribution of Insulin and Akt1 Signaling to Endothelial Nitric Oxide Synthase in the Regulation of Endothelial Function and Blood Pressure , 2009, Circulation Research.

[40]  J. Mieyal,et al.  Regulation by reversible S-glutathionylation: molecular targets implicated in inflammatory diseases. , 2008, Molecules and cells.

[41]  A. Malik,et al.  Regulation of Endothelial Junctional Permeability , 2008, Annals of the New York Academy of Sciences.

[42]  A. Rudich,et al.  Ceramide- and Oxidant-Induced Insulin Resistance Involve Loss of Insulin-Dependent Rac-Activation and Actin Remodeling in Muscle Cells , 2007, Diabetes.

[43]  Jing-kun Pan,et al.  Hyperglycemia Inhibits Retinoic Acid–Induced Activation of Rac1, Prevents Differentiation of Cortical Neurons, and Causes Oxidative Stress in a Rat Model of Diabetic Pregnancy , 2006, Diabetes.

[44]  D. Pimentel,et al.  S-Glutathiolation of p21ras by Peroxynitrite Mediates Endothelial Insulin Resistance Caused by Oxidized Low-Density Lipoprotein , 2006, Arteriosclerosis, thrombosis, and vascular biology.

[45]  O. Ogut,et al.  Decline of contractility during ischemia-reperfusion injury: actin glutathionylation and its effect on allosteric interaction with tropomyosin. , 2006, American journal of physiology. Cell physiology.

[46]  E. Tzima,et al.  Role of Small GTPases in Endothelial Cytoskeletal Dynamics and the Shear Stress Response , 2006, Circulation research.

[47]  D. Pimentel,et al.  S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide , 2004, Nature Medicine.

[48]  Sidney C. Smith,et al.  Atherosclerotic Vascular Disease Conference: Executive summary: Atherosclerotic Vascular Disease Conference proceeding for healthcare professionals from a special writing group of the American Heart Association. , 2004, Circulation.

[49]  Hajime Nakamura,et al.  Glutaredoxin Exerts an Antiapoptotic Effect by Regulating the Redox State of Akt* , 2003, Journal of Biological Chemistry.

[50]  N. Parinandi,et al.  Redox regulation of reactive oxygen species-induced p38 MAP kinase activation and barrier dysfunction in lung microvascular endothelial cells. , 2003, Antioxidants & redox signaling.

[51]  Susan S. Taylor,et al.  Regulation of cAMP-dependent Protein Kinase Activity by Glutathionylation* , 2002, The Journal of Biological Chemistry.

[52]  H. Utsumi,et al.  High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells. , 2000, Diabetes.

[53]  R. Bergman,et al.  Free Fatty Acids and Pathogenesis of Type 2 Diabetes Mellitus , 2000, Trends in Endocrinology & Metabolism.

[54]  C. Ioannides,et al.  Oxidant-induced S-glutathiolation inactivates protein kinase C-alpha (PKC-alpha): a potential mechanism of PKC isozyme regulation. , 2000, Biochemistry.

[55]  P. B. Chock,et al.  Regulation of PTP1B via glutathionylation of the active site cysteine 215. , 1999, Biochemistry.

[56]  R. Ross,et al.  Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse. , 1998, Arteriosclerosis, thrombosis, and vascular biology.

[57]  Yii-Der I. Chen,et al.  Measurement of Plasma Glucose, Free Fatty Acid, Lactate, and Insulin for 24 h in Patients With NIDDM , 1988, Diabetes.

[58]  C. Kilo,et al.  Increased Vascular Permeability in Spontaneously Diabetic BB/W Rats and in Rats With Mild Versus Severe Streptozocin-Induced Diabetes: Prevention by Aldose Reductase Inhibitors and Castration , 1987, Diabetes.

[59]  C. Kilo,et al.  Albumin Permeation of New Vessels Is Increased in Diabetic Rats , 1985, Diabetes.

[60]  H. Edelhauser,et al.  Effect of thiol-oxidation of glutathione with diamide on corneal endothelial function, junctional complexes, and microfilaments , 1976, The Journal of cell biology.

[61]  Arrington,et al.  ' s Accepted Manuscript Redox Regulation of Rac 1 by Thiol Oxidation , 2014 .

[62]  S. Cordwell,et al.  Characterization of reaction conditions providing rapid and specific cysteine alkylation for peptide-based mass spectrometry. , 2013, Biochimica et biophysica acta.

[63]  H. Sumimoto,et al.  Assessment of the role for Rho family GTPases in NADPH oxidase activation. , 2012, Methods in molecular biology.

[64]  Raquel Soares,et al.  Vascular Complications in Diabetes , 2010 .

[65]  Adel Boueiz,et al.  Regulation of endothelial barrier function by reactive oxygen and nitrogen species. , 2009, Microvascular research.

[66]  D. Pimentel,et al.  S-Glutathiolation of p 21 ras by Peroxynitrite Mediates Endothelial Insulin Resistance Caused by Oxidized Low-Density Lipoprotein , 2006 .

[67]  D. Giustarini,et al.  Reversible S-glutathionylation of Cys 374 regulates actin filament formation by inducing structural changes in the actin molecule. , 2003, Free radical biology & medicine.

[68]  M. Cowan,et al.  American Heart Association. , 2018, P & T : a peer-reviewed journal for formulary management.

[69]  J. Błasiak,et al.  Redox Biology , 2018 .