GABA co-released from striatal dopamine axons dampens phasic dopamine release through autoregulatory GABAA receptors

[1]  Michael L. Wallace,et al.  Synaptic and circuit functions of multitransmitter neurons in the mammalian brain , 2023, Neuron.

[2]  N. Tritsch,et al.  Unraveling the dynamics of dopamine release and its actions on target cells , 2023, Trends in Neurosciences.

[3]  B. Averbeck,et al.  Synaptic-like axo-axonal transmission from striatal cholinergic interneurons onto dopaminergic fibers , 2022, Neuron.

[4]  M. Rice,et al.  Leptin Promotes Striatal Dopamine Release via Cholinergic Interneurons and Regionally Distinct Signaling Pathways , 2022, The Journal of Neuroscience.

[5]  C. P. Ford,et al.  Divergent properties and independent regulation of striatal dopamine and GABA co-transmission , 2022, Cell reports.

[6]  S. Hallermann,et al.  An action potential initiation mechanism in distal axons for the control of dopamine release , 2022, Science.

[7]  N. Tritsch,et al.  Inhibitory co-transmission from midbrain dopamine neurons relies on presynaptic GABA uptake , 2021, bioRxiv.

[8]  Lief E. Fenno,et al.  Sox6 expression distinguishes dorsally and ventrally biased dopamine neurons in the substantia nigra with distinctive properties and embryonic origins , 2021, Cell Reports.

[9]  H. Cai,et al.  Diverse midbrain dopaminergic neuron subtypes and implications for complex clinical symptoms of Parkinson’s disease , 2021, Ageing and neurodegenerative diseases.

[10]  S. Mingote,et al.  Dopamine Neurons That Cotransmit Glutamate, From Synapses to Circuits to Behavior , 2021, Frontiers in Neural Circuits.

[11]  M. Rice,et al.  Cell-type-specific disruption of PERK-eIF2α signaling in dopaminergic neurons alters motor and cognitive function , 2021, Molecular Psychiatry.

[12]  Pragya Goel,et al.  Spatial and temporal scales of dopamine transmission , 2021, Nature Reviews Neuroscience.

[13]  M. Rice,et al.  Activity-dependent somatodendritic dopamine release in the substantia nigra autoinhibits the releasing neuron , 2021, Cell reports.

[14]  S. Cragg,et al.  Axonal Modulation of Striatal Dopamine Release by Local γ-Aminobutyric Acid (GABA) Signalling , 2021, Cells.

[15]  C. P. Ford,et al.  Loss of nigral excitation of cholinergic interneurons contributes to parkinsonian motor impairments , 2021, Neuron.

[16]  J. Roeper,et al.  Sex-dependent alterations in behavior, drug responses and dopamine transporter expression in heterozygous DAT-Cre mice , 2021, Scientific Reports.

[17]  M. Ungless,et al.  Tonic GABAergic inhibition, via GABAA receptors containing αβƐ subunits, regulates excitability of ventral tegmental area dopamine neurons , 2021, The European journal of neuroscience.

[18]  B. Matikainen-Ankney,et al.  Ventral arkypallidal neurons inhibit accumbal firing to promote reward consumption. , 2020, Nature Neuroscience.

[19]  Cody A. Siciliano,et al.  Sex differences in dopamine release regulation in the striatum , 2020, Neuropsychopharmacology.

[20]  A. Pérez-Samartín,et al.  GABAA Receptors Expressed in Oligodendrocytes Cultured from the Neonatal Rat Contain α3 and γ1 Subunits and Present Differential Functional and Pharmacological Properties , 2020, Molecular Pharmacology.

[21]  J. Rhee,et al.  Molecular and functional architecture of striatal dopamine release sites , 2020, Neuron.

[22]  Zayd M. Khaliq,et al.  Axonal mechanisms mediating γ-aminobutyric acid receptor type A (GABA-A) inhibition of striatal dopamine release , 2020, eLife.

[23]  S. Cragg,et al.  GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model , 2020, Nature Communications.

[24]  R. España,et al.  Striatal low-threshold spiking interneurons locally gate dopamine , 2020, Current Biology.

[25]  T. Smart,et al.  GABAAR isoform and subunit structural motifs determine synaptic and extrasynaptic receptor localisation , 2020, Neuropharmacology.

[26]  Amy R. Johnson,et al.  Direct dopamine terminal regulation by local striatal microcircuitry , 2020, Journal of neurochemistry.

[27]  J. Berke,et al.  Dopamine release drives motivation, independently from dopamine cell firing , 2019, Neuropsychopharmacology.

[28]  J. Fritschy,et al.  Cell type‐specific distribution of GABAA receptor subtypes in the mouse dorsal striatum , 2019, The Journal of comparative neurology.

[29]  H. Cai,et al.  Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning. , 2019, Cell reports.

[30]  Ilana B. Witten,et al.  Striatal circuits for reward learning and decision-making , 2019, Nature Reviews Neuroscience.

[31]  Pamela F. Marcott,et al.  Synaptic Vesicle Recycling Pathway Determines Neurotransmitter Content and Release Properties , 2019, Neuron.

[32]  Arif A. Hamid,et al.  Dissociable dopamine dynamics for learning and motivation. , 2019, Nature.

[33]  M. Witter,et al.  GABAA Receptor Subunit α3 in Network Dynamics in the Medial Entorhinal Cortex , 2019, Front. Syst. Neurosci..

[34]  S. Cragg,et al.  Inhibition of Nigrostriatal Dopamine Release by Striatal GABAA and GABAB Receptors , 2018, The Journal of Neuroscience.

[35]  Elyssa B. Margolis,et al.  Relative contributions and mapping of ventral tegmental area dopamine and GABA neurons by projection target in the rat , 2018, The Journal of comparative neurology.

[36]  C. P. Ford,et al.  Dopamine Cells Differentially Regulate Striatal Cholinergic Transmission across Regions through Corelease of Dopamine and Glutamate , 2018, Cell reports.

[37]  J. Tepper,et al.  Heterogeneity and Diversity of Striatal GABAergic Interneurons: Update 2018 , 2018, Front. Neuroanat..

[38]  A. Kalmbach,et al.  Dopamine neuron glutamate cotransmission evokes a delayed excitation in lateral dorsal striatal cholinergic interneurons , 2018, eLife.

[39]  C. Aoki,et al.  α4βδ‐GABAA receptors in dorsal hippocampal CA1 of adolescent female rats traffic to the plasma membrane of dendritic spines following voluntary exercise and contribute to protection of animals from activity‐based anorexia through localization at excitatory synapses , 2018, Journal of neuroscience research.

[40]  Matthijs C. Dorst,et al.  Targeting VGLUT2 in Mature Dopamine Neurons Decreases Mesoaccumbal Glutamatergic Transmission and Identifies a Role for Glutamate Co-release in Synaptic Plasticity by Increasing Baseline AMPA/NMDA Ratio , 2018, Front. Neural Circuits.

[41]  Karl Deisseroth,et al.  Mapping projections of molecularly defined dopamine neuron subtypes using intersectional genetic approaches , 2018, Nature Neuroscience.

[42]  Evan Z. Macosko,et al.  Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain , 2018, Cell.

[43]  L. Trudeau,et al.  Segregation of dopamine and glutamate release sites in dopamine neuron axons: regulation by striatal target cells , 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[44]  R. Olsen.  GABAA receptor: Positive and negative allosteric modulators , 2018, Neuropharmacology.

[45]  J. Tepper,et al.  Identification and Characterization of a Novel Spontaneously Active Bursty GABAergic Interneuron in the Mouse Striatum , 2018, The Journal of Neuroscience.

[46]  Y. Ben-Ari,et al.  Striatal dual cholinergic /GABAergic transmission in Parkinson disease: friends or foes? , 2018, Cell stress.

[47]  R. M. Walsh,et al.  Structure of a human synaptic GABA-A receptor , 2018, Nature.

[48]  Y. Ben-Ari,et al.  GABAergic inhibition in dual-transmission cholinergic and GABAergic striatal interneurons is abolished in Parkinson disease , 2018, Nature Communications.

[49]  P. Kaeser,et al.  Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites , 2018, Cell.

[50]  V. Alvarez,et al.  Distinctive Modulation of Dopamine Release in the Nucleus Accumbens Shell Mediated by Dopamine and Acetylcholine Receptors , 2017, The Journal of Neuroscience.

[51]  R. Freyberg,et al.  Neuronal Depolarization Drives Increased Dopamine Synaptic Vesicle Loading via VGLUT , 2017, Neuron.

[52]  D. Lovinger,et al.  Aldehyde dehydrogenase 1–positive nigrostriatal dopaminergic fibers exhibit distinct projection pattern and dopamine release dynamics at mouse dorsal striatum , 2017, Scientific Reports.

[53]  M. Rice,et al.  Characterization of Optically and Electrically Evoked Dopamine Release in Striatal Slices from Digenic Knock-in Mice with DAT-Driven Expression of Channelrhodopsin , 2017, ACS chemical neuroscience.

[54]  K. Deisseroth,et al.  Dopaminergic dynamics underlying sex-specific cocaine reward , 2017, Nature Communications.

[55]  S. Cragg,et al.  Striatal dopamine neurotransmission: regulation of release and uptake. , 2016, Basal ganglia.

[56]  G. Koob,et al.  Sex Differences in Animal Models: Focus on Addiction , 2016, Pharmacological Reviews.

[57]  D. Sulzer,et al.  Fluorescent false neurotransmitter reveals functionally silent dopamine vesicle clusters in the striatum , 2016, Nature Neuroscience.

[58]  Bernardo L. Sabatini,et al.  Mechanisms and functions of GABA co-release , 2016, Nature Reviews Neuroscience.

[59]  J. Patel.  Voltammetry: Electrochemical Detection of Neurotransmitters in the Brain , 2016 .

[60]  Sheila V. Kusnoor,et al.  Functional Connectome Analysis of Dopamine Neuron Glutamatergic Connections in Forebrain Regions , 2015, The Journal of Neuroscience.

[61]  Jun B. Ding,et al.  Aldehyde dehydrogenase 1a1 mediates a GABA synthesis pathway in midbrain dopaminergic neurons , 2015, Science.

[62]  A. Bonci,et al.  Dopaminergic and glutamatergic microdomains within a subset of rodent mesoaccumbens axons , 2015, Nature Neuroscience.

[63]  C. J. Lee,et al.  GABA as a rising gliotransmitter , 2014, Front. Neural Circuits.

[64]  W. Kelsch,et al.  Phasic Dopaminergic Activity Exerts Fast Control of Cholinergic Interneuron Firing via Sequential NMDA, D2, and D1 Receptor Activation , 2014, The Journal of Neuroscience.

[65]  Anatol C. Kreitzer,et al.  Striatal Cholinergic Interneurons Drive GABA Release from Dopamine Terminals , 2014, Neuron.

[66]  B. Sabatini,et al.  Midbrain dopamine neurons sustain inhibitory transmission using plasma membrane uptake of GABA, not synthesis , 2014, eLife.

[67]  Nao Chuhma,et al.  Dopamine Neurons Control Striatal Cholinergic Neurons via Regionally Heterogeneous Dopamine and Glutamate Signaling , 2014, Neuron.

[68]  B. Leitch,et al.  Altered thalamic GABAA‐receptor subunit expression in the stargazer mouse model of absence epilepsy , 2014, Epilepsia.

[69]  A. Dvorzhak,et al.  Reduced tonic inhibition in striatal output neurons from Huntington mice due to loss of astrocytic GABA release through GAT-3 , 2013, Front. Neural Circuits.

[70]  Josiah R. Boivin,et al.  A Causal Link Between Prediction Errors, Dopamine Neurons and Learning , 2013, Nature Neuroscience.

[71]  B. Sabatini,et al.  Dopaminergic Modulation of Synaptic Transmission in Cortex and Striatum , 2012, Neuron.

[72]  R. Betensky,et al.  Corelease of Dopamine and GABA by a Retinal Dopaminergic Neuron , 2012, The Journal of Neuroscience.

[73]  B. Sabatini,et al.  Dopaminergic neurons inhibit striatal output via non-canonical release of GABA , 2012, Nature.

[74]  D. Lovinger,et al.  Selective activation of cholinergic interneurons enhances accumbal phasic dopamine release: setting the tone for reward processing. , 2012, Cell reports.

[75]  K. Deisseroth,et al.  Striatal Dopamine Release Is Triggered by Synchronized Activity in Cholinergic Interneurons , 2012, Neuron.

[76]  Andrea Anzalone,et al.  Dual Control of Dopamine Synthesis and Release by Presynaptic and Postsynaptic Dopamine D2 Receptors , 2012, The Journal of Neuroscience.

[77]  C. Aoki,et al.  Adolescent female rats exhibiting activity‐based anorexia express elevated levels of GABAA receptor α4 and δ subunits at the plasma membrane of hippocampal CA1 spines , 2012, Synapse.

[78]  C. Aoki,et al.  Knockout of the γ-aminobutyric acid receptor subunit α4 reduces functional δ-containing extrasynaptic receptors in hippocampal pyramidal cells at the onset of puberty , 2012, Brain Research.

[79]  Allan R. Jones,et al.  A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing , 2012, Nature Neuroscience.

[80]  T. Hnasko,et al.  Neurotransmitter corelease: mechanism and physiological role. , 2012, Annual review of physiology.

[81]  M. Rice,et al.  Opposing regulation of dopaminergic activity and exploratory motor behavior by forebrain and brainstem cholinergic circuits , 2012, Nature Communications.

[82]  S. Cragg,et al.  Dopamine release in the basal ganglia , 2011, Neuroscience.

[83]  Moonhee Lee,et al.  Mechanisms of GABA release from human astrocytes , 2011, Glia.

[84]  C. Gerfen,et al.  Modulation of striatal projection systems by dopamine. , 2011, Annual review of neuroscience.

[85]  G. Augustine,et al.  Channel-Mediated Tonic GABA Release from Glia , 2010, Science.

[86]  G. Stuber,et al.  Dopaminergic Terminals in the Nucleus Accumbens But Not the Dorsal Striatum Corelease Glutamate , 2010, The Journal of Neuroscience.

[87]  J. Tepper,et al.  Glutamatergic Signaling by Mesolimbic Dopamine Neurons in the Nucleus Accumbens , 2010, The Journal of Neuroscience.

[88]  A. Fenton,et al.  A Critical Role for α4βδ GABAA Receptors in Shaping Learning Deficits at Puberty in Mice , 2010, Science.

[89]  R. Palmiter,et al.  Vesicular Glutamate Transport Promotes Dopamine Storage and Glutamate Corelease In Vivo , 2010, Neuron.

[90]  K. Kullander,et al.  VGLUT2 in dopamine neurons is required for psychostimulant-induced behavioral activation , 2009, Proceedings of the National Academy of Sciences.

[91]  W. Y. Choi,et al.  Dopamine neuron glutamate cotransmission: frequency-dependent modulation in the mesoventromedial projection , 2009, Neuroscience.

[92]  S. Kirischuk,et al.  GABA transporter 1 tunes GABAergic synaptic transmission at output neurons of the mouse neostriatum , 2008, The Journal of physiology.

[93]  J. Fritschy,et al.  Is my antibody‐staining specific? How to deal with pitfalls of immunohistochemistry , 2008, The European journal of neuroscience.

[94]  Werner Sieghart,et al.  International Union of Pharmacology. LXX. Subtypes of γ-Aminobutyric AcidA Receptors: Classification on the Basis of Subunit Composition, Pharmacology, and Function. Update , 2008, Pharmacological Reviews.

[95]  Kristen K. Ade,et al.  Differential Tonic GABA Conductances in Striatal Medium Spiny Neurons , 2008, The Journal of Neuroscience.

[96]  C. Schweizer,et al.  Alteration of GABAergic synapses and gephyrin clusters in the thalamic reticular nucleus of GABAA receptor α3 subunit‐null mice , 2006, The European journal of neuroscience.

[97]  K. Rhodes,et al.  Antibodies as Valuable Neuroscience Research Tools versus Reagents of Mass Distraction , 2006, The Journal of Neuroscience.

[98]  B. Hoffer,et al.  Characterization of a mouse strain expressing Cre recombinase from the 3′ untranslated region of the dopamine transporter locus , 2006, Genesis.

[99]  R. Olsen.  Picrotoxin-like channel blockers of GABAA receptors. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[100]  S. Cragg,et al.  Nicotine amplifies reward-related dopamine signals in striatum , 2004, Nature Neuroscience.

[101]  D. Sulzer,et al.  Frequency-dependent modulation of dopamine release by nicotine , 2004, Nature Neuroscience.

[102]  Kazuto Kobayashi,et al.  Identification of GABAA receptor subunit variants in midbrain dopaminergic neurons , 2004, Journal of Neurochemistry.

[103]  Nao Chuhma,et al.  Dopamine Neurons Mediate a Fast Excitatory Signal via Their Glutamatergic Synapses , 2004, The Journal of Neuroscience.

[104]  Hui Zhang,et al.  Real‐time decoding of dopamine concentration changes in the caudate–putamen during tonic and phasic firing , 2003 .

[105]  P. M. Chan,et al.  Presynaptic control of striatal dopamine neurotransmission in adult vesicular monoamine transporter 2 (VMAT2) mutant mice , 2003, Journal of neurochemistry.

[106]  R. Olsen,et al.  GABAA receptor changes in δ subunit‐deficient mice: Altered expression of α4 and γ2 subunits in the forebrain , 2002 .

[107]  J. Stamford,et al.  Time window of autoreceptor‐mediated inhibition of limbic and striatal dopamine release , 2002, Synapse.

[108]  I. Bermúdez,et al.  Pharmacological properties of nicotinic acetylcholine receptors in isolated Locusta migratoria neurones , 2002, Microscopy research and technique.

[109]  F. Gonon,et al.  Inhibition of Dopamine Release Via Presynaptic D2 Receptors: Time Course and Functional Characteristics In Vivo , 2001, The Journal of Neuroscience.

[110]  John A. Dani,et al.  Endogenous nicotinic cholinergic activity regulates dopamine release in the striatum , 2001, Nature Neuroscience.

[111]  M. Rice,et al.  H(2)O(2) is a novel, endogenous modulator of synaptic dopamine release. , 2001, Journal of neurophysiology.

[112]  G. Sperk,et al.  Distribution of the major γ‐aminobutyric acidA receptor subunits in the basal ganglia and associated limbic brain areas of the adult rat , 2001, The Journal of comparative neurology.

[113]  G. Sperk,et al.  GABAA receptors: immunocytochemical distribution of 13 subunits in the adult rat brain , 2000, Neuroscience.

[114]  M. B. Rooney,et al.  Dopamine release and uptake are greater in female than male rat striatum as measured by fast cyclic voltammetry , 1999, Neuroscience.

[115]  J. Bolam,et al.  Selective Innervation of Neostriatal Interneurons by a Subclass of Neuron in the Globus Pallidus of the Rat , 1998, The Journal of Neuroscience.

[116]  S. Haber,et al.  Dopamine Neurons Make Glutamatergic Synapses In Vitro , 1998, The Journal of Neuroscience.

[117]  T. Klausberger,et al.  Subunit Composition and Quantitative Importance of Hetero-oligomeric Receptors: GABAA Receptors Containing α6 Subunits , 1998, The Journal of Neuroscience.

[118]  S. Cragg,et al.  Differential Autoreceptor Control of Somatodendritic and Axon Terminal Dopamine Release in Substantia Nigra, Ventral Tegmental Area, and Striatum , 1997, The Journal of Neuroscience.

[119]  J. Fritschy,et al.  GABAA‐receptor heterogeneity in the adult rat brain: Differential regional and cellular distribution of seven major subunits , 1995, The Journal of comparative neurology.

[120]  P. Somogyi,et al.  Immunocytochemical Localization of the α1 and β2/3 Subunits of the GABAA Receptor in Relation to Specific GABAergic Synapses in the Dentate Gyrus , 1995 .

[121]  K. Chergui,et al.  Nonlinear relationship between impulse flow, dopamine release and dopamine elimination in the rat brainin vivo , 1994, Neuroscience.

[122]  P. Somogyi,et al.  Synaptic and nonsynaptic localization of the GluR1 subunit of the AMPA- type excitatory amino acid receptor in the rat cerebellum , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[123]  Z. Kruk,et al.  Regional differences in evoked dopamine efflux in brain slices of rat anterior and posterior caudate putamen , 1992, Naunyn-Schmiedeberg's Archives of Pharmacology.

[124]  R. Wightman,et al.  Dynamic Observation of Dopamine Autoreceptor Effects in Rat Striatal Slices , 1992, Journal of neurochemistry.

[125]  Z. Kruk,et al.  Differences in evoked dopamine efflux in rat caudate putamen, nucleus accumbens and tuberculum olfactorium in the absence of uptake inhibition: influence of autoreceptors , 1992, British journal of pharmacology.

[126]  Z. Kruk,et al.  “Real time” measurement of endogenous dopamine release during short trains of pulses in slices of rat neostriatum and nucleus accumbens : role of autoinhibition , 1991, Naunyn-Schmiedeberg's Archives of Pharmacology.

[127]  R. Roth,et al.  Autoreceptor Regulation of Dopamine Synthesis , 1990, Annals of the New York Academy of Sciences.

[128]  A. D. Smith,et al.  The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones , 1990, Trends in Neurosciences.

[129]  J. Millar,et al.  Presynaptic regulation of dopamine release in corpus striatum monitored in vitro in real time by fast cyclic voltammetry , 1990, Brain Research.

[130]  B. Bunney,et al.  Firing properties of substantia nigra dopaminergic neurons in freely moving rats. , 1985, Life sciences.

[131]  A. Grace,et al.  The control of firing pattern in nigral dopamine neurons: single spike firing , 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[132]  A. Grace,et al.  The control of firing pattern in nigral dopamine neurons: burst firing , 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[133]  T. Hnasko,et al.  The multilingual nature of dopamine neurons. , 2014, Progress in brain research.

[134]  C. Barajas-López,et al.  Selectivity of antagonists for the Cys-loop native receptors for ACh, 5-HT and GABA in guinea-pig myenteric neurons. , 2014, Autonomic & autacoid pharmacology.

[135]  M. Rice,et al.  Monitoring axonal and somatodendritic dopamine release using fast-scan cyclic voltammetry in brain slices. , 2013, Methods in molecular biology.

[136]  J. Changeux,et al.  X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation , 2009, Nature.

[137]  Y. Smith,et al.  Microcircuitry of the direct and indirect pathways of the basal ganglia. , 1998, Neuroscience.