Emerin plays a crucial role in nuclear invagination and in the nuclear calcium transient

[1]  W. Shimizu,et al.  Flecainide ameliorates arrhythmogenicity through NCX flux in Andersen-Tawil syndrome-iPS cell-derived cardiomyocytes , 2017, Biochemistry and biophysics reports.

[2]  Chikaaki Motoda,et al.  Embryonic type Na+ channel β-subunit, SCN3B masks the disease phenotype of Brugada syndrome , 2016, Scientific Reports.

[3]  Insa M. A. Wolf,et al.  Ca(2+) microdomains, NAADP and type 1 ryanodine receptor in cell activation. , 2016, Biochimica et biophysica acta.

[4]  D. Levy,et al.  Recent advances in understanding nuclear size and shape , 2016, Nucleus.

[5]  M. Suematsu,et al.  Glutamine Oxidation Is Indispensable for Survival of Human Pluripotent Stem Cells. , 2016, Cell metabolism.

[6]  S. Wakabayashi,et al.  Stimulus-Dependent Regulation of Nuclear Ca2+ Signaling in Cardiomyocytes: A Role of Neuronal Calcium Sensor-1 , 2015, PloS one.

[7]  Chikaaki Motoda,et al.  Impaired respiratory function in MELAS-induced pluripotent stem cells with high heteroplasmy levels , 2015, FEBS open bio.

[8]  D. Bers,et al.  Nuclear Calcium in Cardiac Myocytes , 2015, Journal of cardiovascular pharmacology.

[9]  R. Hajjar,et al.  Altered myocardial calcium cycling and energetics in heart failure--a rational approach for disease treatment. , 2015, Cell metabolism.

[10]  J. Finsterer,et al.  Dilated, Arrhythmogenic Cardiomyopathy in Emery-Dreifuss Muscular Dystrophy Due to the Emerin Splice-Site Mutation c.449 + 1G>A , 2014, Cardiology.

[11]  K. Node,et al.  Endothelin‐1 Induces Myofibrillar Disarray and Contractile Vector Variability in Hypertrophic Cardiomyopathy–Induced Pluripotent Stem Cell–Derived Cardiomyocytes , 2014, Journal of the American Heart Association.

[12]  C. D. dos Remedios,et al.  Nuclear pore rearrangements and nuclear trafficking in cardiomyocytes from rat and human failing hearts , 2014, Cardiovascular research.

[13]  J. Vicencio,et al.  An integrated mechanism of cardiomyocyte nuclear Ca(2+) signaling. , 2014, Journal of molecular and cellular cardiology.

[14]  Jie Liu,et al.  Polydatin attenuates cardiac hypertrophy through modulation of cardiac Ca2+ handling and calcineurin-NFAT signaling pathway. , 2014, American journal of physiology. Heart and circulatory physiology.

[15]  G. Gundersen,et al.  Muscular Dystrophy-Associated SUN1 and SUN2 Variants Disrupt Nuclear-Cytoskeletal Connections and Myonuclear Organization , 2014, PLoS genetics.

[16]  Zhengmao Hu,et al.  Whole exome sequencing identifies a novel EMD mutation in a Chinese family with dilated cardiomyopathy , 2014, BMC Medical Genetics.

[17]  D. Levy,et al.  Sizing and shaping the nucleus: mechanisms and significance. , 2014, Current opinion in cell biology.

[18]  Ju Chen,et al.  Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease. , 2014, Circulation research.

[19]  M. Murata,et al.  Generation and Characterization of Functional Cardiomyocytes Derived from Human T Cell-Derived Induced Pluripotent Stem Cells , 2014, PloS one.

[20]  G. Scarano,et al.  Intergenerational and intrafamilial phenotypic variability in 22q11.2 Deletion syndrome subjects , 2014, BMC Medical Genetics.

[21]  M. Luo,et al.  Mechanisms of Altered Ca2+ Handling in Heart Failure , 2013, Circulation research.

[22]  K. Wilson,et al.  The nuclear envelope LEM-domain protein emerin , 2013, Nucleus.

[23]  Gillian H. Little,et al.  Nuclear CaMKII enhances histone H3 phosphorylation and remodels chromatin during cardiac hypertrophy , 2013, Nucleic acids research.

[24]  R. Blum,et al.  Direct imaging of ER calcium with targeted-esterase induced dye loading (TED). , 2013, Journal of visualized experiments : JoVE.

[25]  Henry M Colecraft,et al.  L-type calcium channel targeting and local signalling in cardiac myocytes. , 2013, Cardiovascular research.

[26]  S. Yuasa,et al.  Novel insights into disease modeling using induced pluripotent stem cells. , 2013, Biological & pharmaceutical bulletin.

[27]  O. Larsson,et al.  Local Control of Nuclear Calcium Signaling in Cardiac Myocytes by Perinuclear Microdomains of Sarcolemmal Insulin-Like Growth Factor 1 Receptors , 2013, Circulation research.

[28]  Y. Kanda,et al.  Investigation of the freely available easy-to-use software ‘EZR' for medical statistics , 2012, Bone Marrow Transplantation.

[29]  M. Hetzer,et al.  Outfits for different occasions: tissue-specific roles of Nuclear Envelope proteins. , 2012, Current opinion in cell biology.

[30]  Shinsuke Yuasa,et al.  Disease characterization using LQTS-specific induced pluripotent stem cells. , 2012, Cardiovascular research.

[31]  Shinsuke Yuasa,et al.  Generation of induced pluripotent stem cells from a small amount of human peripheral blood using a combination of activated T cells and Sendai virus , 2012, Nature Protocols.

[32]  J. Molkentin,et al.  Unraveling the secrets of a double life: contractile versus signaling Ca2+ in a cardiac myocyte. , 2012, Journal of molecular and cellular cardiology.

[33]  J. Mauger Role of the nuclear envelope in calcium signalling , 2012, Biology of the cell.

[34]  S. Yuasa,et al.  Derivation of induced pluripotent stem cells from human peripheral circulating T cells. , 2011, Current protocols in stem cell biology.

[35]  Andrew L. Miller,et al.  Calcium signaling in cardiac myocytes. , 2011, Cold Spring Harbor perspectives in biology.

[36]  I. Nonaka,et al.  TMEM43 mutations in emery‐dreifuss muscular dystrophy‐related myopathy , 2011, Annals of neurology.

[37]  B. Pieske,et al.  In situ calibration of nucleoplasmic versus cytoplasmic Ca²+ concentration in adult cardiomyocytes. , 2011, Biophysical journal.

[38]  Shinsuke Yuasa,et al.  Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells. , 2010, Cell stem cell.

[39]  Robert R. Snapp,et al.  Tissue stretch induces nuclear remodeling in connective tissue fibroblasts , 2010, Histochemistry and Cell Biology.

[40]  M. Bootman,et al.  An update on nuclear calcium signalling , 2009, Journal of Cell Science.

[41]  K. Mikoshiba,et al.  Endothelin-1-stimulated InsP3-induced Ca2+ release is a nexus for hypertrophic signaling in cardiac myocytes. , 2009, Molecular cell.

[42]  J. Holaska,et al.  Emerin and the nuclear lamina in muscle and cardiac disease. , 2008, Circulation research.

[43]  D. Bers Calcium cycling and signaling in cardiac myocytes. , 2008, Annual review of physiology.

[44]  Juliet A. Ellis,et al.  Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity. , 2007, Human molecular genetics.

[45]  Juliet A. Ellis,et al.  Emery-Dreifuss muscular dystrophy at the nuclear envelope: 10 years on , 2006, Cellular and Molecular Life Sciences CMLS.

[46]  E. Olson,et al.  CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy. , 2006, The Journal of clinical investigation.

[47]  Robert D. Gerard,et al.  The Transcriptional Coactivator CAMTA2 Stimulates Cardiac Growth by Opposing Class II Histone Deacetylases , 2006, Cell.

[48]  Tong Zhang,et al.  Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling. , 2006, The Journal of clinical investigation.

[49]  Shinsuke Yuasa,et al.  Analysis of the electrophysiological properties and arrhythmias in directly contacted skeletal and cardiac muscle cell sheets. , 2005, Cardiovascular research.

[50]  K. Hayashi,et al.  High Incidence of Sudden Cardiac Death With Conduction Disturbances and Atrial Cardiomyopathy Caused by a Nonsense Mutation in the STA Gene , 2005, Circulation.

[51]  Arantxa González,et al.  Mechanisms of Disease: pathologic structural remodeling is more than adaptive hypertrophy in hypertensive heart disease , 2005, Nature Clinical Practice Cardiovascular Medicine.

[52]  R. Ledeen,et al.  Presence of Sodium–Calcium Exchanger/GM1 Complex in the Nuclear Envelope of Non-neural Cells: Nature of Exchanger-GM1 Interaction , 2004, Neurochemical Research.

[53]  J. Molkentin,et al.  Calcium-calcineurin signaling in the regulation of cardiac hypertrophy. , 2004, Biochemical and biophysical research communications.

[54]  W. Zipfel,et al.  Regulation of calcium signals in the nucleus by a nucleoplasmic reticulum , 2003, Nature Cell Biology.

[55]  K. Wilson,et al.  Nesprin‐1α self‐associates and binds directly to emerin and lamin A in vitro , 2002 .

[56]  B. Abrenica,et al.  Nucleoplasmic Ca2+loading is regulated by mobilization of perinuclear Ca2+ , 2000 .

[57]  R. Passier,et al.  CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo. , 2000, The Journal of clinical investigation.

[58]  Y. Hirota,et al.  Visualization of biphasic Ca2+ diffusion from cytosol to nucleus in contracting adult rat cardiac myocytes with an ultra-fast confocal imaging system. , 1999, Cell calcium.

[59]  F. Muntoni,et al.  Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy , 1999, Nature Genetics.

[60]  R C Dunn,et al.  Calcium regulation of nuclear pore permeability. , 1998, Cell calcium.

[61]  M. Fricker,et al.  Interphase Nuclei of Many Mammalian Cell Types Contain Deep, Dynamic, Tubular Membrane-bound Invaginations of the Nuclear Envelope , 1997, The Journal of cell biology.

[62]  S. Manilal,et al.  The Emery-Dreifuss muscular dystrophy protein, emerin, is a nuclear membrane protein. , 1996, Human molecular genetics.

[63]  T. Tsukahara,et al.  Emerin deficiency at the nuclear membrane in patients with Emery-Dreif uss muscular dystrophy , 1996, Nature Genetics.

[64]  Julie Bossuyt Nuclear remodelling: a consequence of nucleocytoplasmic traffic run amok? , 2015, Cardiovascular research.

[65]  遠山 周吾 Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes , 2013 .

[66]  D. Jacques,et al.  Presence of tubular and reticular structures in the nucleus of human vascular smooth muscle cells. , 2011, Journal of molecular and cellular cardiology.

[67]  J. Benitah,et al.  L-type Ca(2+) current in ventricular cardiomyocytes. , 2010, Journal of molecular and cellular cardiology.

[68]  E. Sasaki,et al.  Nongenetic method for purifying stem cell–derived cardiomyocytes , 2010, Nature Methods.

[69]  Margaret Comerford Freda,et al.  10 Years. , 2008, MCN. The American journal of maternal child nursing.

[70]  E. Olson,et al.  CaMKIIdelta isoforms differentially affect calcium handling but similarly regulate HDAC/MEF2 transcriptional responses. , 2007, The Journal of biological chemistry.

[71]  G. Leitinger,et al.  Early Remodelling of Perinuclear Ca 2+ Stores and Nucleoplasmic Ca 2+ Signalling during the Development of Hypertrophy and Heart Failure Running Title: Ljubojevic Et Al.; Early Remodelling of Perinuclear Ca 2+ Stores , 2022 .