Uveitis survey in children

Background/aims: This is a retrospective cohort uveitis survey to determine the clinical features of uveitis in children and assess the rate of complications at two referral centres in Saudi Arabia. Methods: All children under the age of 16 years presenting with uveitis for the first time between 1997 and 2007 to The Eye Center and King Khaled Eye Specialist Hospital in Riyadh, Saudi Arabia were included. Clinical features of uveitis entities were described. Last follow-up visual acuity and ocular complications were analysed. Results: A total of 163 cases of uveitis in children were included. The age range was 1–16 years with a mean age of 10 years. The most frequent clinical type of uveitis in children included acute anterior non-granulomatous uveitis 26%, intermediate uveitis 20%, Vogt–Koyanagi–Harada (VKH) disease 16% and juvenile idiopathic arthritis (JIA) 15%. Anterior uveitis accounted for 42%, intermediate for 20%, posterior for 7%, and panuveitis for 31%. Immune-mediated uveitis was present in 144 (88%) patients, while infectious causes manifested in 19 (12%) patients. Conclusions: The most common cause of uveitis in children was anterior non-granulomatous uveitis of undetermined aetiology. There was a high prevalence of intermediate uveitis, VKH and JIA. Infectious causes of uveitis were uncommon.

[1]  Douglas A Jabs,et al.  Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. , 2005, American journal of ophthalmology.

[2]  S. Androudi,et al.  Analysis of pediatric uveitis cases at a tertiary referral center. , 2005, Ophthalmology.

[3]  Andrew D. Dick,et al.  The standardization of uveitis nomenclature (SUN) working group; standardization of uveitis nomenclature for reporting clinical data: Results of the first international workshop , 2005 .

[4]  W. Feuer,et al.  Ocular complications of pediatric uveitis. , 2004, Ophthalmology.

[5]  D. Gritz,et al.  Incidence and prevalence of uveitis in Northern California , 2004 .

[6]  D. Gritz,et al.  Incidence and prevalence of uveitis in Northern California; the Northern California Epidemiology of Uveitis Study. , 2004, Ophthalmology.

[7]  N. Wulffraat,et al.  Visual loss in uveitis of childhood , 2003, The British journal of ophthalmology.

[8]  C. Edelsten,et al.  Visual loss associated with pediatric uveitis in english primary and referral centers. , 2003, American journal of ophthalmology.

[9]  K. Tabbara,et al.  Causes of uveitis at The Eye Center in Saudi Arabia: A retrospective review , 2002, Ophthalmic epidemiology.

[10]  D. Benezra,et al.  Patterns of intraocular inflammation in children. , 2001, Bulletin de la Societe belge d'ophtalmologie.

[11]  P. Stoffel,et al.  Non‐infectious causes of uveitis in 70 Swiss children , 2000, Acta paediatrica.

[12]  J. Tuominen,et al.  Uveitis in children: population-based study in Finland. , 2000, Acta ophthalmologica Scandinavica.

[13]  M. Soylu,et al.  Pediatric uveitis in southern Turkey. , 1997, Ocular immunology and inflammation.

[14]  P. Pivetti-Pezzi Uveitis in Children , 1996, European journal of ophthalmology.

[15]  N. Rao Uveitis in Children , 2003 .

[16]  E. Perkins Pattern of uveitis in children. , 1966, The British journal of ophthalmology.

[17]  R. Witmer,et al.  [Uveitis in childhood]. , 1966, Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde.

[18]  Cross Ag Uveitis in children. , 1965 .

[19]  L. Kurland,et al.  Epidemiology of uveitis. Incidence and prevalence in a small urban community. , 1962, Archives of ophthalmology.