Effectiveness of self-management training in type 2 diabetes: a systematic review of randomized controlled trials.

OBJECTIVE To systematically review the effectiveness of self-management training in type 2 diabetes. RESEARCH DESIGN AND METHODS MEDLINE, Educational Resources Information Center (ERIC), and Nursing and Allied Health databases were searched for English-language articles published between 1980 and 1999. Studies were original articles reporting the results of randomized controlled trials of the effectiveness of self-management training in people with type 2 diabetes. Relevant data on study design, population demographics, interventions, outcomes, methodological quality, and external validity were tabulated. Interventions were categorized based on educational focus (information, lifestyle behaviors, mechanical skills, and coping skills), and outcomes were classified as knowledge, attitudes, and self-care skills; lifestyle behaviors, psychological outcomes, and quality of life; glycemic control; cardiovascular disease risk factors; and economic measures and health service utilization. RESULTS A total of 72 studies described in 84 articles were identified for this review. Positive effects of self-management training on knowledge, frequency and accuracy of self-monitoring of blood glucose, self-reported dietary habits, and glycemic control were demonstrated in studies with short follow-up (<6 months). Effects of interventions on lipids, physical activity, weight, and blood pressure were variable. With longer follow-up, interventions that used regular reinforcement throughout follow-up were sometimes effective in improving glycemic control. Educational interventions that involved patient collaboration may be more effective than didactic interventions in improving glycemic control, weight, and lipid profiles. No studies demonstrated the effectiveness of self-management training on cardiovascular disease-related events or mortality; no economic analyses included indirect costs; few studies examined health-care utilization. Performance, selection, attrition, and detection bias were common in studies reviewed, and external generalizability was often limited. CONCLUSIONS Evidence supports the effectiveness of self-management training in type 2 diabetes, particularly in the short term. Further research is needed to assess the effectiveness of self-management interventions on sustained glycemic control, cardiovascular disease risk factors, and ultimately, microvascular and cardiovascular disease and quality of life.

[1]  R. Stuart Adherence, Compliance and Generalization in Behavioral Medicine , 1982 .

[2]  R. Tattersall,et al.  Influence of imaginative teaching of diet on compliance and metabolic control in insulin dependent diabetes. , 1983, British medical journal.

[3]  M. Uusitupa,et al.  A Controlled Trial on the Effects of Patient Education in the Treatment of Insulin-dependent Diabetes , 1983, Diabetes Care.

[4]  S. Rabkin,et al.  A Randomized Clinical Trial Comparing Behavior Modification and Individual Counseling in the Nutritional Therapy of Non-insulin-dependent Diabetes Mellitus: Comparison of the Effect on Blood Sugar, Body Weight, and Serum Lipids , 1983, Diabetes Care.

[5]  J. Stafford,et al.  The Effectiveness of Diabetes Education for Non-Insulin-Dependent Diabetic Persons , 1984, The Diabetes educator.

[6]  A randomized, controlled study on the effect of diabetes counseling in the offices of 12 general practitioners. , 1984, Revue d'epidemiologie et de sante publique.

[7]  A randomized, controlled comparison of instruction by a diabetes educator versus self-instruction in self-monitoring of blood glucose. , 1985 .

[8]  R. Kaplan,et al.  Prospective Evaluation of HDL Cholesterol Changes After Diet and Physical Conditioning Programs for Patients with Type II Diabetes Mellitus , 1985, Diabetes Care.

[9]  H. Shamoon,et al.  Self-Monitoring of Capillary Blood Glucose: Changing the Performance of Individuals with Diabetes , 1985, Diabetes Care.

[10]  L. Epstein,et al.  Behavior change, weight loss, and physiological improvements in type II diabetic patients. , 1985, Journal of consulting and clinical psychology.

[11]  M L Wheeler,et al.  Evaluation of Computer-based Diet Education in Persons with Diabetes Mellitus and Limited Educational Background , 1985, Diabetes Care.

[12]  P D Mullen,et al.  Clinical trials of patient education for chronic conditions: a comparative meta-analysis of intervention types. , 1985, Preventive medicine.

[13]  W. Ward,et al.  A Randomized, Controlled Comparison of Instruction by a Diabetes Educator Versus Self-Instruction in Self-Monitoring of Blood Glucose , 1985, Diabetes Care.

[14]  R. Recker,et al.  A Randomized Study of the Effects of a Home Diabetes Education Program , 1986, Diabetes Care.

[15]  C. A. Nugent,et al.  Management of Obese Patients With Diabetes Mellitus: Comparison of Advice Education With Group Management , 1986, Diabetes Care.

[16]  N. Fineberg,et al.  The Diabetes Education Study: A Controlled Trial of the Effects of Diabetes Patient Education , 1986, Diabetes Care.

[17]  L. Epstein,et al.  Does self-monitoring of blood glucose levels improve dietary compliance for obese patients with type II diabetes? , 1986, The American journal of medicine.

[18]  L. Epstein,et al.  Calorie-counting compared to exchange system diets in the treatment of overweight patients with type II diabetes. , 1986, Addictive behaviors.

[19]  Gruber Sb,et al.  Clinical Epidemiology: The Architecture of Clinical Research. , 1986 .

[20]  R. Kaplan,et al.  Comparison of behavioral interventions for control of type II diabetes mellitus , 1986 .

[21]  K. Meadows,et al.  Effect of Computer-Based Learning on Diabetes Knowledge and Control , 1986, Diabetes Care.

[22]  M. Falkenberg,et al.  Problem oriented participatory education in the guidance of adults with non-insulin-treated type-II diabetes mellitus. , 1986, Scandinavian journal of primary health care.

[23]  E. Bartlett,et al.  Historical glimpses of patient education in the United States. , 1986, Patient education and counseling.

[24]  M. Uusitupa,et al.  Efficacy of dietary instructions in newly diagnosed non-insulin-dependent diabetic patients. Comparison of two different patient education regimens. , 2009, Acta medica Scandinavica.

[25]  C. Pratt,et al.  The impact of diabetes education and peer support upon weight and glycemic control of elderly persons with noninsulin dependent diabetes mellitus (NIDDM). , 1987, American journal of public health.

[26]  W. Karmally,et al.  Randomized, Controlled Trial of Diabetic Patient Education: Improved Knowledge Without Improved Metabolic Status , 1987, Diabetes Care.

[27]  C. Pratt,et al.  Peer support and nutrition education for older adults with diabetes. , 1987, Journal of nutrition for the elderly.

[28]  P Ours,et al.  DIABEDS: a randomized trial of the effects of physician and/or patient education on diabetes patient outcomes. , 1987, Journal of chronic diseases.

[29]  Sharon A. Brown Effects of Educational Interventions In Diabetes Care: A Meta‐Analysis of Findings , 1988, Nursing research.

[30]  L. Epstein,et al.  Self-regulation in the treatment of type II diabetes , 1988 .

[31]  I. Lauder,et al.  An assessment of drug information sheets for diabetic patients: only active involvement by patients is helpful. , 1988, Diabetes research and clinical practice.

[32]  I. Raz,et al.  Influence of Small-Group Education Sessions on Glucose Homeostasis in NIDDM , 1988, Diabetes Care.

[33]  K. Meadows,et al.  Knowledge Profile and Control in Diabetic Patients , 1988, Diabetic medicine : a journal of the British Diabetic Association.

[34]  R. Tattersall,et al.  Group Education for Obese Patients with Type 2 Diabetes: Greater Success at Less Cost , 1988, Diabetic medicine : a journal of the British Diabetic Association.

[35]  M. Hynes,et al.  Meta-analysis of the effects of educational and psychosocial interventions on management of diabetes mellitus. , 1988, Journal of clinical epidemiology.

[36]  Alvan R. Feinstein,et al.  Clinical Epidemiology: The Architecture of Clinical Research , 1988 .

[37]  G. Slama,et al.  Is glucose self-monitoring beneficial in non-insulin-treated diabetic patients? Results of a randomized comparative trial. , 1989, Diabete & metabolisme.

[38]  E. R. Wood,et al.  Evaluation of a hospital-based education program for patients with diabetes. , 1989, Journal of the American Dietetic Association.

[39]  R. Glasgow,et al.  Nutrition Education and Social Learning Interventions for Type II Diabetes , 1989, Diabetes Care.

[40]  G. A. Holloway,et al.  Prevention of amputation by diabetic education. , 1989, American journal of surgery.

[41]  R. G. Cornell,et al.  Effects of Peer-Group Intervention on Metabolic Control of Adolescents With IDDM: Randomized Outpatient Study , 1989, Diabetes Care.

[42]  Adriaan Visser,et al.  Attitude Behaviour Theories and Diabetes Education Programmes , 1989 .

[43]  I. Weerdt,et al.  Randomized controlled evaluation of an education program for insulin treated patients with diabetes: Effects on psychosocial variables , 1989 .

[44]  S. Brown Quality of reporting in diabetes patient education research: 1954-1986. , 1990, Research in nursing & health.

[45]  L. Simons,et al.  Impact of Intensive Educational Approach to Dietary Change in NIDDM , 1990, Diabetes Care.

[46]  R. Elton,et al.  A Project in Diabetes Education for Children , 1990, Diabetic medicine : a journal of the British Diabetic Association.

[47]  Continuing Diabetes Education by Telephone , 1990, Diabetic medicine : a journal of the British Diabetic Association.

[48]  S A Brown,et al.  Studies of educational interventions and outcomes in diabetic adults: a meta-analysis revisited. , 1990, Patient education and counseling.

[49]  G. Jansen,et al.  Educating patients with diabetes: comparison of nutrient-based and exchange group methods. , 1990, Journal of the American Dietetic Association.

[50]  Phyllis M. Jones Use of a Course on Self-Control Behavior Techniques to Increase Adherence to Prescribed Frequency for Self-Monitoring Blood Glucose , 1990, The Diabetes educator.

[51]  L. Anderson Health-Care Communication and Selected Psychosocial Correlates of Adherence in Diabetes Management , 1990, Diabetes Care.

[52]  K. Mann,et al.  Follow-up Intervention: Its Effect on Compliance Behavior to a Diabetes Regimen , 1990, The Diabetes educator.

[53]  G. Kok,et al.  Randomized Controlled Multicentre Evaluation of an Education Programme for Insulin‐treated Diabetic Patients: Effects on Metabolic Control, Quality of Life, and Costs of Therapy , 1991, Diabetic medicine : a journal of the British Diabetic Association.

[54]  M. Hanefeld,et al.  Diabetes Intervention Study: Multi-Intervention Trial in Newly Diagnosed NIDDM , 1991, Diabetes Care.

[55]  M. Funnell,et al.  Empowerment: An Idea Whose Time Has Come in Diabetes Education , 1991, The Diabetes educator.

[56]  L. Campbell,et al.  Intensive Education Improves Knowledge, Compliance, and Foot Problems in Type 2 Diabetes , 1991, Diabetic medicine : a journal of the British Diabetic Association.

[57]  E. Villagomez,et al.  Diabetes Education in a Mexican-American Population: Pilot Testing of a Research-Based Videotape , 1992, The Diabetes educator.

[58]  S. Kruger,et al.  Foot Care: Knowledge Retention and Self-care Practices , 1992, The Diabetes educator.

[59]  P. Lewinsohn,et al.  Improving self-care among older patients with type II diabetes: the "Sixty Something..." Study. , 1992, Patient education and counseling.

[60]  M. Hendryx,et al.  Diabetes Support Groups Improve Health Care of Older Diabetic Patients , 1992, Journal of the American Geriatrics Society.

[61]  R. Glasgow,et al.  Evaluating Diabetes Education: Are we measuring the most important outcomes? , 1992, Diabetes Care.

[62]  H. Farreny,et al.  Telematic expert system Diabeto: New Tool for Diet Self-Monitoring for Diabetic Patients , 1992, Diabetes Care.

[63]  J Wylie-Rosett,et al.  Metabolic Impact of Education in NIDDM , 1992, Diabetes Care.

[64]  D. Ronis,et al.  Behavioral Analysis and Behavioral Strategies to Improve Self-Management of Type II Diabetes , 1993, Clinical nursing research.

[65]  M. Uusitupa,et al.  Impact of intensified dietary therapy on energy and nutrient intakes and fatty acid composition of serum lipids in patients with recently diagnosed non-insulin-dependent diabetes mellitus. , 1993, Journal of the American Dietetic Association.

[66]  Knowledge about diabetes and metabolic control in diabetic patients. , 1993, The Ceylon medical journal.

[67]  D. Bild,et al.  Reduction of Lower Extremity Clinical Abnormalities in Patients with Non-Insulin-Dependent Diabetes Mellitus , 1993, Annals of Internal Medicine.

[68]  A R Jadad,et al.  Searching the literature. Be systematic in your searching. , 1993, BMJ.

[69]  M. Uusitupa,et al.  The maintenance of improved metabolic control after intensified diet therapy in recent type 2 diabetes. , 1993, Diabetes research and clinical practice.

[70]  Fernando Dj Knowledge about diabetes and metabolic control in diabetic patients. , 1993 .

[71]  Work absenteeism in type 2 diabetes mellitus: results of the prospective Diabetes Intervention Study. , 1993, Diabete & metabolisme.

[72]  K. Tu,et al.  Diabetes Self-Care Knowledge, Behaviors, and Metabolic Control of Older Adults — The Effect of a Posteducational Follow-up Program , 1993, The Diabetes educator.

[73]  K C Stange,et al.  Multimethod research: approaches for integrating qualitative and quantitative methods. , 1994, Journal of general internal medicine.

[74]  G. Frost,et al.  Dietary Advice Based on the Glycaemic Index Improves Dietary Profile and Metabolic Control in Type 2 Diabetic Patients , 1994, Diabetic medicine : a journal of the British Diabetic Association.

[75]  K. Dickersin,et al.  Systematic Reviews: Identifying relevant studies for systematic reviews , 1994 .

[76]  M. Wierenga Life-style modification for weight control to improve diabetes health status. , 1994, Patient education and counseling.

[77]  A. Mason,et al.  A Comparison of Learning Activity Packages and Classroom Instruction for Diet Management of Patients with Non-Insulin-Dependent Diabetes Mellitus , 1994, The Diabetes educator.

[78]  Frederick Mosteller,et al.  Guidelines for Meta-analyses Evaluating Diagnostic Tests , 1994, Annals of Internal Medicine.

[79]  M. Saunders,et al.  Utilizing a 24-Hour Dietary Recall and Culturally Specific Diabetes Education in Mexican Americans With Diabetes , 1994, The Diabetes educator.

[80]  R. Bergenstal,et al.  Cost-effectiveness of medical nutrition therapy provided by dietitians for persons with non-insulin-dependent diabetes mellitus. , 1995, Journal of the American Dietetic Association.

[81]  S. Clement,et al.  Diabetes Self-Management Education , 1995, Diabetes Care.

[82]  R. J. Hayes,et al.  Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. , 1995, JAMA.

[83]  R. Bergenstal,et al.  Effectiveness of medical nutrition therapy provided by dietitians in the management of non-insulin-dependent diabetes mellitus: a randomized, controlled clinical trial. , 1995, Journal of the American Dietetic Association.

[84]  C. Counsell,et al.  Identifying relevant studies for systematic reviews , 1995, BMJ.

[85]  R. Koff,et al.  Meta-analysis, decision analysis, and cost-effectiveness analysis. Methods for quantitative synthesis in medicine , 1995 .

[86]  M. Clarke,et al.  Identifying relevant studies for systematic reviews , 1995, BMJ.

[87]  N. G. Popovich,et al.  Developing and Implementing a Pharmaceutical Care Model in an Ambulatory Care Setting for Patients With Diabetes , 1995, The Diabetes educator.

[88]  Can patients set their own educational priorities? , 1995, Diabetes research and clinical practice.

[89]  M. Funnell,et al.  Patient Empowerment: Results of a randomized controlled trial , 1995, Diabetes Care.

[90]  National Standards for Diabetes Self-Management Education Programs , 1995, Diabetes Care.

[91]  R. Glasgow,et al.  A brief office-based intervention to facilitate diabetes dietary self-management. , 1995, Health education research.

[92]  M. Uusitupa Early lifestyle intervention in patients with non-insulin-dependent diabetes mellitus and impaired glucose tolerance. , 1996, Annals of medicine.

[93]  American Diabetes Association Annual Meeting 1996: Managed Care and Change in Medicine , 1996, Diabetes Care.

[94]  R E Glasgow,et al.  Effects of a Brief Office-Based Intervention to Facilitate Diabetes Dietary Self-Management , 1996, Diabetes Care.

[95]  Cindy Farquhar,et al.  3 The Cochrane Library , 1996 .

[96]  D. Thompson,et al.  Cost-effectiveness of medical nutrition therapy. , 1996, Journal of the American Dietetic Association.

[97]  R. Sanson-Fisher,et al.  The Relative Effectiveness of Educational and Behavioral Instruction Programs for Patients With NIDDM: A Randomized Trial , 1996, The Diabetes educator.

[98]  Brian T. Austin,et al.  Organizing care for patients with chronic illness. , 1996, The Milbank quarterly.

[99]  R Lo,et al.  The development and evaluation of a computer-aided diabetes education program. , 1996, The Australian journal of advanced nursing : a quarterly publication of the Royal Australian Nursing Federation.

[100]  F. Schellevis,et al.  The Efficacy of Self-Monitoring of Blood Glucose in NIDDM subjects: A criteria-based literature review , 1997, Diabetes Care.

[101]  R. Stoupa,et al.  Demonstrating the added value of community health nursing for clients with insulin-dependent diabetes. , 1997, Journal of community health nursing.

[102]  J. Schaefer,et al.  Collaborative Management of Chronic Illness , 1997, Annals of Internal Medicine.

[103]  K. Hawthorne,et al.  One-to-one teaching with pictures--flashcard health education for British Asians with diabetes. , 1997, The British journal of general practice : the journal of the Royal College of General Practitioners.

[104]  S. Kumanyika,et al.  A Randomized Controlled Trial of Weight Reduction and Exercise for Diabetes Management in Older African-American Subjects , 1997, Diabetes Care.

[105]  Jesse A Berlin,et al.  Does blinding of readers affect the results of meta-analyses? , 1997, The Lancet.

[106]  C. Counsell,et al.  Formulating Questions and Locating Primary Studies for Inclusion in Systematic Reviews , 1997, Annals of Internal Medicine.

[107]  J. Mann,et al.  Lifestyle intervention in people with insulin-dependent diabetes mellitus (IDDM) , 1997, European Journal of Clinical Nutrition.

[108]  M Gallichan,et al.  Self monitoring of glucose by people with diabetes: evidence based practice , 1997, BMJ.

[109]  Pierre-Andre La Chance,et al.  Long-term effects and costs of brief behavioural dietary intervention for patients with diabetes delivered from the medical office. , 1997, Patient education and counseling.

[110]  T D Koepsell,et al.  Dietary assessment instruments are susceptible to intervention-associated response set bias. , 1998, Journal of the American Dietetic Association.

[111]  J. Pugh,et al.  Patient Choice in Diabetes Education Curriculum: Nutritional versus standard content for type 2 diabetes , 1998, Diabetes Care.

[112]  C. Palmer,et al.  Is intensive dietetic intervention effective for overweight patients with diabetes mellitus? A randomized controlled study in a general practice , 1999 .

[113]  C. Basch,et al.  The effect of health education on the rate of ophthalmic examinations among African Americans with diabetes mellitus. , 1999, American journal of public health.

[114]  C. Hanis,et al.  Culturally Competent Diabetes Education for Mexican Americans: The Starr County Study , 1999, The Diabetes educator.

[115]  K. Flegal,et al.  Racial and ethnic differences in glycemic control of adults with type 2 diabetes. , 1999, Diabetes care.

[116]  R. Glasgow,et al.  In diabetes care, moving from compliance to adherence is not enough. Something entirely different is needed. , 1999, Diabetes care.

[117]  L. Harvill,et al.  Improved control of type 2 diabetes mellitus: a practical education/behavior modification program in a primary care clinic. , 1999, Southern medical journal.

[118]  R. Glasgow,et al.  Evaluating the public health impact of health promotion interventions: the RE-AIM framework. , 1999, American journal of public health.

[119]  R. Little Recent progress in glycohemoglobin (HbA1c) testing. , 2000, Diabetes care.

[120]  M. Berger,et al.  Randomized controlled trials remain fundamental to clinical decision making in Type II diabetes mellitus: a comment to the debate on randomized controlled trials , 2000, Diabetologia.

[121]  D. Kent,et al.  Are randomized controlled trials sufficient evidence to guide clinical practice in Type II (non-insulin-dependent) diabetes mellitus? , 2000, Diabetologia.