Chapter 18. Vitamin D: Metabolism and Mechanism of Action
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[1] H. DeLuca,et al. Metabolism of 25-hydroxyvitamin D3 by rat kidney cells in culture: isolation and identification of cis- and trans-19-nor-10-oxo-25-hydroxyvitamin D3. , 1984, Archives of biochemistry and biophysics.
[2] H. DeLuca,et al. 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3: a highly potent, long-lasting analog of 1,25-dihydroxyvitamin D3. , 1984, Archives of biochemistry and biophysics.
[3] S. Yamada,et al. Isolation, identification, and metabolism of (23S,25R)-25-hydroxyvitamin D3 26,23-lactol. A biosynthetic precursor of (23S,25R)-25-hydroxyvitamin D3 26,23-lactone. , 1984, The Journal of biological chemistry.
[4] R. Horst,et al. C(24)- and C(23)-oxidation, converging pathways of intestinal 1,25-dihydroxyvitamin D3 metabolism: identification of 24-keto-1,23,25-trihydroxyvitamin D3. , 1983, Biochemistry.
[5] A. Norman,et al. Isolation and identification of 1,25-dihydroxy-24-oxo-vitamin D3 and 1,23,25-trihydroxy-24-oxo-vitamin D3. New metabolites of vitamin D3 produced by a C-24 oxidation pathway of metabolism for 1,25-dihydroxyvitamin D3 present in intestine and kidney. , 1983, The Journal of biological chemistry.
[6] U. Liberman,et al. Hereditary resistance to 1,25-dihydroxyvitamin D: defective function of receptors for 1,25-dihydroxyvitamin D in cells cultured from bone. , 1983, The Journal of clinical endocrinology and metabolism.
[7] M. Huang,et al. 1 alpha, 25-Dihydroxyvitamin D3 inhibits phorbol ester-dependent chemical carcinogenesis in mouse skin. , 1983, Biochemical and biophysical research communications.
[8] H. DeLuca,et al. Support of embryonic chick survival by vitamin D metabolites. , 1983, Archives of biochemistry and biophysics.
[9] M. Warner. 25-hydroxyvitamin D hydroxylation. Evidence for a dioxygenase activity of solubilized renal mitochondrial cytochrome P-450. , 1983, Journal of Biological Chemistry.
[10] H. DeLuca,et al. Cellular mechanisms of insulin release: the effects of vitamin D deficiency and repletion on rat insulin secretion. , 1983, Endocrinology.
[11] P. Reitsma,et al. Induction of monocytic differentiation and bone resorption by 1,25-dihydroxyvitamin D3. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[12] H. DeLuca,et al. Stimulation of 1,25-dihydroxyvitamin D3 production by 1,25-dihydroxyvitamin D3 in the hypocalcaemic rat. , 1983, The Biochemical journal.
[13] N. Ikekawa,et al. Metabolism and binding properties of 24,24-difluoro-25-hydroxyvitamin D3. , 1983, Archives of biochemistry and biophysics.
[14] H. DeLuca,et al. 1 alpha,25-dihydroxyvitamin D3 promotes fusion of mouse alveolar macrophages both by a direct mechanism and by a spleen cell-mediated indirect mechanism. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[15] H. DeLuca,et al. Natural 25,26-dihydroxyvitamin D3 is an epimeric mixture. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[16] J. Eisman,et al. Inhibition of human cancer cell growth by 1,25-dihydroxyvitamin D3 metabolites. , 1983, Cancer research.
[17] R. Horst,et al. Intestinal synthesis of 24-keto-1,25-dihydroxyvitamin D3. A metabolite formed in vivo with high affinity for the vitamin D cytosolic receptor. , 1983, The Journal of biological chemistry.
[18] H. DeLuca,et al. Biological activity of 24,24-difluoro-25-hydroxycholecalciferol in chicks. , 1983, The Journal of nutrition.
[19] A. Norman,et al. Unoccupied and in vitro and in vivo occupied 1,25-dihydroxyvitamin D3 intestinal receptors. Multiple biochemical forms and evidence for transformation. , 1983, The Journal of biological chemistry.
[20] M. Haussler,et al. Association of 1,25-dihydroxyvitamin D3 with cultured 3T6 mouse fibroblasts. Cellular uptake and receptor-mediated migration to the nucleus. , 1983, The Journal of biological chemistry.
[21] M. Uskoković,et al. 19-nor-10-ketovitamin D derivatives: unique metabolites of vitamin D3, vitamin D2, and 25-hydroxyvitamin D3. , 1983, Biochemistry.
[22] R. Horst,et al. (23S)-1,23,25-Trihydroxycholecalciferol, an intestinal metabolite of 1,25-dihydroxycholecalciferol. , 1983, The Biochemical journal.
[23] S. Andersson,et al. 25-hydroxylation of C27-steroids and vitamin D3 by a constitutive cytochrome P-450 from rat liver microsomes. , 1983, The Journal of biological chemistry.
[24] H. DeLuca,et al. Purification of the receptor for 1 alpha,25-dihydroxyvitamin D3 from chicken intestine. , 1983, Biochemistry.
[25] H. DeLuca,et al. Quantitation of endogenously occupied and unoccupied binding sites for 1,25-dihydroxyvitamin D3 in rat intestine. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[26] H. DeLuca,et al. Studies on the site of 1,25-dihydroxyvitamin D3 synthesis in vivo. , 1983, The Journal of biological chemistry.
[27] R. Kumar,et al. Do tissues other than the kidney produce 1,25-dihydroxyvitamin D3 in vivo? A reexamination. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[28] H. DeLuca,et al. Biological activity of 24,24-difluoro-1,25-dihydroxyvitamin D3. , 1983, The American journal of physiology.
[29] M. Haussler,et al. Serum and monoclonal antibodies against the chick intestinal receptor for 1,25-dihydroxyvitamin D3. Generation by a preparation enriched in a 64,000-dalton protein. , 1983, The Journal of biological chemistry.
[30] H. DeLuca,et al. Induction of calcium-binding protein before 1,25-dihydroxyvitamin D3 stimulation of duodenal calcium uptake. , 1983, The Journal of biological chemistry.
[31] R. Horst,et al. 23-Keto-25-hydroxyvitamin D3: a vitamin D3 metabolite with high affinity for the 1,25-dihydroxyvitamin D specific cytosol receptor. , 1983, Biochemistry.
[32] M. Ohmori,et al. Isolation and identification of 1 alpha- and 23-hydroxylated metabolites of 25-hydroxy-24-oxovitamin D3 from in vitro incubates of chick kidney homogenates. , 1983, The Journal of biological chemistry.
[33] A. Norman,et al. Isolation and identification of 25-hydroxyvitamin D3-26,23-peroxylactone. A novel in vivo metabolite of vitamin D3. , 1982, The Journal of biological chemistry.
[34] H. DeLuca,et al. Stimulation of specific 1,25-dihydroxyvitamin D3 binding protein in cultured postnatal rat intestine by hydrocortisone. , 1982, The Journal of biological chemistry.
[35] M. Warner. Catalytic activity of partially purified renal 25-hydroxyvitamin D hydroxylases from vitamin D-deficient and vitamin D-replete rats. , 1982, The Journal of biological chemistry.
[36] L. Orci,et al. The vitamin D endocrine system: steroid metabolism, hormone receptors, and biological response (calcium binding proteins). , 1982, Endocrine reviews.
[37] N. Ikekawa,et al. 25-hydroxy-26, 26,26,27,27,27-hexafluorovitamin D3: biological activity in the rat. , 1982, Archives of biochemistry and biophysics.
[38] R. Horst,et al. 23-keto-25-hydroxyvitamin D3 and 23-keto-1,25-dihydroxyvitamin D3: two new vitamin D3 metabolites with high affinity for the 1,25-dihydroxyvitamin D3 receptor. , 1982, Biochemical and biophysical research communications.
[39] M. Uskoković,et al. 23S,25-dihydroxyvitamin D3 as a circulating metabolite of vitamin D3. Its role in 25-hydroxyvitamin D3-26,23-lactone biosynthesis. , 1982, The Journal of biological chemistry.
[40] A. Norman,et al. Isolation, identification, and biological activity of 23,25,26-trihydroxyvitamin D3, an in vitro and in vivo metabolite of vitamin D3. , 1982, Archives of biochemistry and biophysics.
[41] H. DeLuca,et al. 24-hydroxylation of 25-hydroxyvitamin D3: is it required for embryonic development in chicks? , 1982, Science.
[42] R. Horst,et al. 23, 25, 26-trihydroxycholecalciferol. A 25-hydroxycholecalciferol-26,23-lactone precursor. , 1982, The Biochemical journal.
[43] E. Abe,et al. 1 alpha,25-Dihydroxycholecalciferol and a human myeloid leukaemia cell line (HL-60). , 1982, The Biochemical journal.
[44] A. Norman,et al. Effect of vitamin D status on the equilibrium between occupied and unoccupied 1,25-dihydroxyvitamin D intestinal receptors in the chick. , 1982, The Journal of clinical investigation.
[45] H. DeLuca,et al. Brain target sites for 1,25-dihydroxyvitamin D3. , 1982, Science.
[46] R. Turner,et al. Evidence for extrarenal production of 1 alpha ,25-dihydroxyvitamin D in man. , 1982, The Journal of clinical investigation.
[47] H. DeLuca,et al. 23,24,25-Trihydroxyvitamin D3, 24,25,26-trihydroxyvitamin D3, 24-keto-25-hydroxyvitamin D3, and 23-dehydro-25-hydroxyvitamin D3: new in vivo metabolites of vitamin D3. , 1981, Biochemistry.
[48] H. DeLuca,et al. Synthesis and determination of configuration of natural 25-hydroxyvitamin D(3) 26,23-lactone. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[49] M. Uskoković,et al. 1 Alpha-25,26-trihydroxyvitamin D3: an in vivo and in vitro metabolite of vitamin D3. , 1981, Biochemistry.
[50] H. Rasmussen,et al. LIPONOMIC REGULATION OF CALCIUM TRANSPORT BY 1,25(OH)2D3 * , 1981, Annals of the New York Academy of Sciences.
[51] G. Howard,et al. Human bone cells in culture metabolize 25-hydroxyvitamin D3 to 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3. , 1981, The Journal of biological chemistry.
[52] H. DeLuca,et al. 1,25,26-trihydroxyvitamin D3: isolation, identification, and biological activity. , 1981, Archives of biochemistry and biophysics.
[53] H. Sakagami,et al. Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[54] H. DeLuca,et al. Binding proteins for vitamin D metabolites: serum carriers and intracellular receptors. , 1981, Archives of biochemistry and biophysics.
[55] H. DeLuca,et al. Appearance of the intestinal cytosolic receptor for 1,25-dihydroxyvitamin D3 during neonatal development in the rat. , 1981, The Journal of biological chemistry.
[56] U. Liberman,et al. A cellular defect in hereditary vitamin-D-dependent rickets type II: defective nuclear uptake of 1,25-dihydroxyvitamin D in cultured skin fibroblasts. , 1981, The New England journal of medicine.
[57] H. DeLuca,et al. Isolation and identification of 23,25-dihydroxyvitamin D3, an in vivo metabolite of vitamin D3. , 1981, Biochemistry.
[58] B. Lythgoe. Simonsen Lecture. Synthetic approaches to vitamin D and its relatives , 1981 .
[59] H. DeLuca,et al. An examination of the importance of 24-hydroxylation to the function of vitamin D during early development. , 1981, Endocrinology.
[60] B. Halloran,et al. Intestinal calcium transport: evidence for two distinct mechanisms of action of 1,25-dihydroxyvitamin D3. , 1981, Archives of biochemistry and biophysics.
[61] H. DeLuca,et al. The effect of inhibitors of protein and RNA synthesis on 1 alpha,25-dihydroxyvitamin D3-dependent calcium uptake in cultured embryonic chick duodenum. , 1981, The Journal of biological chemistry.
[62] H. DeLuca,et al. 23,25-Dihydroxyvitamin D3: a natural precursor in the biosynthesis of 25-hydroxyvitamin D3-26,23-lactone. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[63] S. Yamada,et al. Isolation, identification, and biological activity of 25-hydroxy-24-oxovitamin D3: a new metabolite of vitamin D3 generated by in vitro incubations with kidney homogenates. , 1981, Biochemistry.
[64] M. Harding,et al. 1,25-Dihydroxycholecalciferol stimulation of a mitochondrial protein in chick intestinal cells , 1980, Nature.
[65] H. DeLuca,et al. 1,25-Dihydroxyvitamin D3 stimulated increase of 7,8-didehydrocholesterol levels in rat skin. , 1980, Biochemistry.
[66] H. DeLuca,et al. Role of kidney tissue in the production of 25-hydroxyvitamin D3-26,23-lactone and 1 alpha, 25-dihydroxyvitamin D3-26,23-lactone. , 1980, Proceedings of the National Academy of Sciences of the United States of America.
[67] H. Armbrecht,et al. Effect of age on the conversion of 25-hydroxyvitamin D3 to 1,25-dihydroxyvitamin D3 by kidney of rat. , 1980, The Journal of clinical investigation.
[68] J. Puzas,et al. In vitro synthesis of 1 alpha,25-dihydroxycholecalciferol and 24,25-dihydroxycholecalciferol by isolated calvarial cells. , 1980, Proceedings of the National Academy of Sciences of the United States of America.
[69] N. Ikekawa,et al. Synthesis of 26,26,26,27,27,27-hexafluoro-25-hydroxyvitamin D3 , 1980 .
[70] H. DeLuca,et al. Resolution and reconstitution of soluble components of rat liver microsomal vitamin D3-25-hydroxylase. , 1980, Archives of biochemistry and biophysics.
[71] H. DeLuca,et al. Metabolites of 1 alpha, 25-dihydroxyvitamin D3 in rat bile. , 1980, Biochemistry.
[72] G. Grodsky,et al. Vitamin D deficiency inhibits pancreatic secretion of insulin. , 1980, Science.
[73] S. Klahr,et al. Lack of a direct effect of 1,25-dihydroxycholecalciferol on parathyroid hormone secretion by normal bovine parathyroid glands. , 1980, Endocrinology.
[74] A. Norman,et al. Unoccupied 1,25-dihydroxyvitamin D3 receptors. Nuclear/cytosol ratio depends on ionic strength. , 1980, The Journal of biological chemistry.
[75] J. Eisman,et al. Receptors for 1,25(OH)2‐vitamin D3 enriched in cloned osteoblast‐like rat osteogenic sarcoma cells , 1980, FEBS letters.
[76] J. I. Pedersen,et al. Properties of a reconstituted vitamin D3 25-hydroxylase from rat liver mitochondria. , 1980, The Journal of biological chemistry.
[77] H. DeLuca,et al. An in vitro study of the stability of the chicken intestinal cytosol 1,25-dihydroxyvitamin D3-specific receptor. , 1980, Archives of biochemistry and biophysics.
[78] J. Eisman,et al. 1,25-DIHYDROXYVITAMIN D3 RECEPTORS IN CANCER , 1980, The Lancet.
[79] H. DeLuca,et al. Purification and properties of chick renal mitochondrial ferredoxin. , 1980, Biochemistry.
[80] H. DeLuca,et al. Renal mitochondrial ferredoxin active in 25-hydroxyvitamin D3 1 alpha-hydroxylase. Characterization of the iron-sulfur cluster using interprotein cluster transfer and electron paramagnetic resonance spectroscopy. , 1980, Biochemistry.
[81] R. I. Yakhimovich. The Synthesis of Active Metabolites and Analogues of Vitamin D3 , 1980 .
[82] H. DeLuca,et al. Cellular and subcellular localization of 1,25-(OH)2-vitamin D3 in rat kidney: comparison with localization of parathyroid hormone and estradiol. , 1980, Proceedings of the National Academy of Sciences of the United States of America.
[83] H. DeLuca,et al. 24,24-difluoro-1,25-dihydroxyvitamin D3: in vitro production, isolation, and biological activity. , 1980, Archives of biochemistry and biophysics.
[84] J. Eisman,et al. 1,25-DIHYDROXYVITAMIN-D RECEPTOR IN BREAST CANCER CELLS , 1979, The Lancet.
[85] R. Vieth,et al. Kinetic behavior of 25-hydroxyvitamin D-1-hydroxylase and -24-hydroxylase in rat kidney mitochondria. , 1979, The Journal of biological chemistry.
[86] H. DeLuca,et al. Characteristics of the rat liver microsomal enzyme system converting cholecalciferol into 25-hydroxycholecalciferol. Evidence for the participation of cytochrome p-450. , 1979, The Biochemical journal.
[87] H. DeLuca,et al. Target cells for 1,25-dihydroxyvitamin D3 in intestinal tract, stomach, kidney, skin, pituitary, and parathyroid. , 1979, Science.
[88] M. Haussler,et al. Purification of chicken intestinal receptor for 1,25-dihydroxyvitamin D. , 1979, Proceedings of the National Academy of Sciences of the United States of America.
[89] H. DeLuca,et al. 25-Hydroxyvitamin D3 26,23-lactone: a new in vivo metabolite of vitamin D. , 1979, Biochemistry.
[90] H. DeLuca,et al. In vitro production of 1,25-dihydroxyvitamin D3 by rat placental tissue. , 1979, Proceedings of the National Academy of Sciences of the United States of America.
[91] Y. Weisman,et al. 1α, 25-Dihydroxyvitamin D3, and 24,25-dihydroxyvitamin D3 in vitro synthesis by human decidua and placenta , 1979, Nature.
[92] H. DeLuca,et al. Isolation and characterization of 1 alpha-hydroxy-23-carboxytetranorvitamin D: a major metabolite of 1,25-dihydroxyvitamin D3. , 1979, Biochemistry.
[93] H. DeLuca,et al. Biological activity of 24,24-difluoro-25-hydroxyvitamin D3. Effect of blocking of 24-hydroxylation on the functions of vitamin D. , 1979, The Journal of biological chemistry.
[94] H. Fleisch,et al. Regulation of the metabolism of 25-hydroxyvitamin D3 in primary cultures of chick kidney cells. , 1979, The Journal of clinical investigation.
[95] H. Rasmussen,et al. The effect of 1alpha-hydroxyvitamin D3 administration on calcium transport in chick intestine brush border membrane vesicles. , 1979, The Journal of biological chemistry.
[96] H. Henry. Regulation of the hydroxylation of 25-hydroxyvitamin D3 in vivo and in primary cultures of chick kidney cells. , 1979, The Journal of biological chemistry.
[97] H. DeLuca,et al. Metabolism and excretion of 3H-1,25-(OH)2-vitamin D3 in healthy adults. , 1978, The Journal of clinical endocrinology and metabolism.
[98] P. Wilson,et al. The relationship between vitamin D-stimulated calcium transport and intestinal calcium-binding protein in the chicken. , 1978, The Biochemical journal.
[99] E. Ogata,et al. In vivo evidence for the intermediary role of 3',5'-cyclic AMP in parathyroid hormone-induced stimulation of 1alpha,25-dihydroxyvitamin D3 synthesis in rats. , 1977, Endocrinology.
[100] H. DeLuca,et al. Intestinal cytosol binders of 1,25-dihydroxyvitamin D and 25-hydroxyvitamin D. , 1976, Archives of biochemistry and biophysics.
[101] H. DeLuca,et al. 1,25-Dihydroxyvitamin D in biological fluids: a simplified and sensitive assay. , 1976, Science.
[102] H. DeLuca,et al. The role of 1,25-dihydroxyvitamin D3 and parathyroid hormone in the regulation of chick renal 25-hydroxyvitamin D3-24-hydroxylase. , 1975, Archives of biochemistry and biophysics.
[103] R. Larkins,et al. Feedback control of vitamin D metabolism by a nuclear action of 1,25-dihydroxycholecalciferol on the kidney , 1974, Nature.
[104] H. DeLuca,et al. Response of intestinal calcium transport and bone calcium mobilization to 1,25-dihydroxyvitamin D3 in thyroparathyroidectomized rats. , 1974, Endocrinology.
[105] J. Potts. Hormonal Control of Calcium Metabolism , 1971 .
[106] H. DeLuca,et al. Influence of sodium on calcium transport by the rat small intestine. , 1969, The American journal of physiology.
[107] R. Wasserman,et al. Vitamin D3-Induced Calcium-Binding Protein in Chick Intestinal Mucosa , 1966, Science.
[108] H. DeLuca,et al. Vitamin D: recent advances. , 1983, Annual review of biochemistry.
[109] T. Terada,et al. Studies on organic fluorine compounds. Part 37. Studies on steroids. Part 78. Synthesis of 24,24-difluoro- and 24ξ-fluoro-25-hydroxyvitamin D3 , 1982 .
[110] H. DeLuca,et al. Purification of chicken intestinal receptor for 1 alpha, 25-dihydroxyvitamin D3 to apparent homogeneity. , 1982, Proceedings of the National Academy of Sciences of the United States of America.
[111] A. Norman,et al. Production in vitro of 1α,25-dihydroxyvitamin D3-26,23-lactone from 1α,25-dihydroxyvitamin D3 by rat small intestinal mucosa homogenates , 1982 .
[112] H. DeLuca,et al. Measurement of chick kidney 25-hydroxyvitamin D3-1 alpha-hydroxylase without use of radioactive substrate. , 1981, Analytical biochemistry.
[113] N. Ikekawa,et al. Synthesis of 26,26,26-trifluoro-25-hydroxy and 27-nor-26,26,26-trifluoro-25-hydroxyvitamin D3 , 1981 .
[114] H. DeLuca,et al. Synthesis of calcitroic acid, a metabolite of 1.alpha.,25-dihydroxycholecalciferol , 1981 .
[115] A. Norman,et al. Factors affecting the distribution and stability of unoccupied 1,25-dihydroxyvitamin D3 receptors. , 1981, Journal of receptor research.
[116] H. DeLuca,et al. Measurement of mammalian 25-hydroxyvitamin D3 24R-and 1 alpha-hydroxylase. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[117] S. Yamada,et al. 24,24-Difluoro-25-hydroxyvitamin D3-enhanced bone mineralization in rats. Comparison with 25-hydroxyvitamin3 and vitamin D3. , 1981, Archives of biochemistry and biophysics.
[118] H. DeLuca,et al. Vitamin D. Basic research and its clinical application. , 1979 .
[119] M. Ohmori,et al. Synthesis of 24,24-difluoro-25-hydroxyvitamin D3 , 1979 .
[120] R. H. Wasserman,et al. Calcium-binding proteins and calcium function , 1977 .
[121] H. DeLuca,et al. Metabolism and mechanism of action of vitamin D. , 1976, Annual review of biochemistry.