Computer simulation of a living cell

Abstract This paper, which is being presented in two parts, is concerned with the problem of a realistic and useful simulation of a living cell, the simple unicellular bacterium Escherichia coli, the program being written in Fortran IV for an IBM 360/67 computer. The object is to represent the cell in such a way as to simulate its growth in real environments of a living cell, as well as during changes from one chemical environment to another. This simulation could also supply useful information for answering current questions in biology. In Part 2 of this paper the authors describe the method of evolving DNA and discuss cancer in relation to the computer simulation under consideration. Literature references cited in both parts of the paper, as well as the appendix to the work, are also presented.