Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission

[1]  A. Tewari,et al.  Sex differences in SARS-CoV-2 infection rates and the potential link to prostate cancer , 2020, Communications Biology.

[2]  C. Torp‐Pedersen,et al.  Association between male sex and outcomes of Coronavirus Disease 2019 (Covid‐19) – a Danish nationwide, register-based study , 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[3]  F. Hernández,et al.  ACE2 is on the X chromosome: could this explain COVID-19 gender differences? , 2020, European heart journal.

[4]  S. Klein,et al.  Considering how biological sex impacts immune responses and COVID-19 outcomes , 2020, Nature Reviews Immunology.

[5]  K. Brengel-Pesce,et al.  Type I interferon in children with viral or bacterial infections. , 2020, Clinical chemistry.

[6]  S. Oertelt-Prigione,et al.  Towards Precision Medicine: Inclusion of Sex and Gender Aspects in COVID-19 Clinical Studies—Acting Now before It Is Too Late—A Joint Call for Action , 2020, International journal of environmental research and public health.

[7]  S. Singh,et al.  Gender-Based Disparities in COVID-19: Clinical Characteristics and Propensity-matched Analysis of Outcomes , 2020, medRxiv.

[8]  K. Brengel-Pesce,et al.  Type I IFN immunoprofiling in COVID-19 patients , 2020, Journal of Allergy and Clinical Immunology.

[9]  R. José,et al.  COVID-19 cytokine storm: the interplay between inflammation and coagulation , 2020, The Lancet Respiratory Medicine.

[10]  Eun Ji Kim,et al.  Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. , 2020, JAMA.

[11]  Jiang Chang,et al.  A Multi-hospital Study in Wuhan, China：Protective Effects of Non-menopause and Female Hormones on SARS-CoV-2 infection , 2020, medRxiv.

[12]  A. M. Leontovich,et al.  The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 , 2020, Nature Microbiology.

[13]  Wei Wang,et al.  Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis , 2020, European Respiratory Journal.

[14]  De-Min Han,et al.  Gender Differences in Patients With COVID-19: Focus on Severity and Mortality , 2020, Frontiers in Public Health.

[15]  Ting Yu,et al.  Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study , 2020, The Lancet Respiratory Medicine.

[16]  G. Cai.  Bulk and single-cell transcriptomics identify tobacco-use disparity in lung gene expression of ACE2, the receptor of 2019-nCov , 2020, medRxiv.

[17]  Yan Zhao,et al.  Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. , 2020, JAMA.

[18]  Ralph S. Baric,et al.  Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus , 2020, Journal of Virology.

[19]  W. Zuo,et al.  Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-nCov , 2020, bioRxiv.

[20]  Coronavirus Disease 2019 (COVID-19) Daily Situation Report by the Robert Koch Institute , 2020 .

[21]  中国疾病预防控制中心新型冠状病毒肺炎应急响应机制流行病学组.  The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China./ 新型冠状病毒肺炎流行病学特征分析 , 2020 .

[22]  Ops. Oms.  Enfermedad por el Coronavirus (COVID-19) , 2020 .

[23]  China Cdc Weekly.  The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) — China, 2020 , 2020, China CDC weekly.

[24]  Gerta Rücker,et al.  How to perform a meta-analysis with R: a practical tutorial , 2019, Evidence-Based Mental Health.

[25]  J. Shaw,et al.  Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition. , 2019, Diabetes research and clinical practice.

[26]  J. Banchereau,et al.  Sexual-dimorphism in human immune system aging , 2019, Nature Communications.

[27]  S. Klein,et al.  The intersection of sex and gender in the treatment of influenza. , 2019, Current opinion in virology.

[28]  D. Schaid,et al.  Sex Differences in Older Adults' Immune Responses to Seasonal Influenza Vaccination , 2019, Front. Immunol..

[29]  P. Oliveri,et al.  Sex and Pubertal Differences in the Type 1 Interferon Pathway Associate With Both X Chromosome Number and Serum Sex Hormone Concentration , 2019, Front. Immunol..

[30]  S. Klein,et al.  The Confluence of Sex Hormones and Aging on Immunity , 2018, Front. Immunol..

[31]  C. Ihekweazu,et al.  The Nigeria Centre for Disease Control , 2018, BMJ Global Health.

[32]  A. Cohen,et al.  Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes? , 2018, Front. Immunol..

[33]  R. Donnelly,et al.  Inherent X-Linked Genetic Variability and Cellular Mosaicism Unique to Females Contribute to Sex-Related Differences in the Innate Immune Response , 2017, Front. Immunol..

[34]  S. Klein,et al.  Sex and Gender Differences in the Outcomes of Vaccination over the Life Course. , 2017, Annual review of cell and developmental biology.

[35]  M. Altfeld,et al.  Human Immunodeficiency Virus 1 and Type I Interferons—Where Sex Makes a Difference , 2017, Front. Immunol..

[36]  A. Goette,et al.  Protective regulation of the ACE2/ACE gene expression by estrogen in human atrial tissue from elderly men , 2017, Experimental biology and medicine.

[37]  M. Fornage,et al.  Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association , 2017, Circulation.

[38]  M. Altfeld,et al.  Human pDCs display sex‐specific differences in type I interferon subtypes and interferon α/β receptor expression , 2017, European journal of immunology.

[39]  S. Klein,et al.  Sex differences in immune responses , 2016, Nature Reviews Immunology.

[40]  M. Atchison,et al.  Unusual maintenance of X chromosome inactivation predisposes female lymphocytes for increased expression from the inactive X , 2016, Proceedings of the National Academy of Sciences.

[41]  D. Khan,et al.  The Immune System Is a Natural Target for Estrogen Action: Opposing Effects of Estrogen in Two Prototypical Autoimmune Diseases , 2016, Front. Immunol..

[42]  Howard Y. Chang,et al.  Individuality and variation of personal regulomes in primary human T cells. , 2015, Cell systems.

[43]  B. Walker,et al.  Sex Differences in Antiretroviral Therapy Initiation in Pediatric HIV Infection , 2015, PloS one.

[44]  S. Klein,et al.  Sex-based differences in immune function and responses to vaccination. , 2015, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[45]  C. Aspord,et al.  X-Chromosome Complement and Estrogen Receptor Signaling Independently Contribute to the Enhanced TLR7-Mediated IFN-α Production of Plasmacytoid Dendritic Cells from Women , 2014, The Journal of Immunology.

[46]  S. Almalki,et al.  The pattern of Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive epidemiological analysis of data from the Saudi Ministry of Health , 2014, International journal of general medicine.

[47]  Mark M. Davis,et al.  Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination , 2013, Proceedings of the National Academy of Sciences.

[48]  R. Trivedi,et al.  Estrogen Deficiency Induces the Differentiation of IL-17 Secreting Th17 Cells: A New Candidate in the Pathogenesis of Osteoporosis , 2012, PloS one.

[49]  C. Sawyer.  Child Mortality Estimation: Estimating Sex Differences in Childhood Mortality since the 1970s , 2012, PLoS medicine.

[50]  Vera Regitz‐Zagrosek,et al.  Sex and gender differences in health , 2012, EMBO reports.

[51]  M. Gershwin,et al.  The X chromosome and immune associated genes. , 2012, Journal of autoimmunity.

[52]  J. Arnal,et al.  The TLR-mediated response of plasmacytoid dendritic cells is positively regulated by estradiol in vivo through cell-intrinsic estrogen receptor α signaling. , 2012, Blood.

[53]  M. Abdullah,et al.  Gender effect on in vitro lymphocyte subset levels of healthy individuals. , 2012, Cellular immunology.

[54]  Brian C. Zanoni,et al.  Sex differences in HIV RNA level and CD4 cell percentage during childhood. , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[55]  Susan Michie,et al.  Experimental pretesting of hand-washing interventions in a natural setting. , 2009, American journal of public health.

[56]  M. Altfeld,et al.  Sex differences in the Toll-like receptor–mediated response of plasmacytoid dendritic cells to HIV-1 , 2009, Nature Medicine.

[57]  S. Pauklin,et al.  Estrogen directly activates AID transcription and function , 2009, The Journal of experimental medicine.

[58]  B. Richardson,et al.  Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis , 2008, Genes and Immunity.

[59]  W. Carr,et al.  Half- vs full-dose trivalent inactivated influenza vaccine (2004-2005): age, dose, and sex effects on immune responses. , 2008, Archives of internal medicine.

[60]  P. Formenty,et al.  Addressing sex and gender in epidemic-prone infectious diseases , 2007 .

[61]  H. Hackstein,et al.  TLR7 Ligands Induce Higher IFN-α Production in Females1 , 2006, The Journal of Immunology.

[62]  P. Nelson,et al.  Effect of medical castration on CD4+ CD25+ T cells, CD8+ T cell IFN-gamma expression, and NK cells: a physiological role for testosterone and/or its metabolites. , 2006, American journal of physiology. Endocrinology and metabolism.

[63]  Y. Leo,et al.  SARS in Singapore--predictors of disease severity. , 2006, Annals of the Academy of Medicine, Singapore.

[64]  M. Heineman,et al.  Sex hormones and the immune response in humans. , 2005, Human reproduction update.

[65]  S. Ziegler,et al.  Cutting Edge: Estrogen Drives Expansion of the CD4+CD25+ Regulatory T Cell Compartment1 , 2004, The Journal of Immunology.

[66]  D. Chong,et al.  Do Men Have a Higher Case Fatality Rate of Severe Acute Respiratory Syndrome than Women Do? , 2004, American journal of epidemiology.

[67]  P. Zabel,et al.  Gender differences in human sepsis. , 1998, Archives of surgery.

[68]  M. Kazatchkine,et al.  Gender differences in CD4+ cell counts persist after HIV‐1 infection , 1997 .

[69]  H. Whittle,et al.  T-lymphocyte subsets in West African children: impact of age, sex, and season. , 1997, The Journal of pediatrics.

[70]  M. Kazatchkine,et al.  Gender difference in CD4+ cell counts persist after HIV-1 infection. SEROCO Study Group. , 1997, AIDS.

[71]  F. Chew,et al.  Age- and sex-related changes in lymphocyte subpopulations of healthy Asian subjects: from birth to adulthood. , 1996, Cytometry.

[72]  M. Wolzt,et al.  Effects of 17 beta-estradiol on circulating adhesion molecules. , 1994, The Journal of clinical endocrinology and metabolism.

[73]  A Wolman,et al.  Public health and the environment. , 1985, American journal of public health.

[74]  G. Stoica,et al.  Biologic variation of human immunoglobulin concentration. I. Sex-age specific effects on serum levels of IgG, IgA, IgM and IgD. , 1980, Medecine interne.

[75]  R. Cross.  The Illinois Department of Public Health. , 1955, The Illinois medical journal.

[76]  Lisa R Roberts.  PUBLIC HEALTH SERVICES , 1923, The Medical journal of Australia.