Genetic and psychosocial influence on the association between early childhood infections and later psychiatric disorders

To evaluate the influence of extensive genetic and psychosocial confounding on the association between early childhood infection and five major psychiatric disorders

[1]  K. Carter,et al.  The familial risk of infection-related hospitalization in children: A population-based sibling study , 2021, PloS one.

[2]  Clara Albiñana,et al.  Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction , 2020, bioRxiv.

[3]  M. Nordentoft,et al.  Efficacy and safety of anti-inflammatory agents in treatment of psychotic disorders – A comprehensive systematic review and meta-analysis , 2020, Brain, Behavior, and Immunity.

[4]  L. Petersen,et al.  Polygenic risk score for bipolar disorder and school grades. , 2020, Journal of affective disorders.

[5]  K. Kendler,et al.  Applying Causal Inference Methods in Psychiatric Epidemiology: A Review. , 2019, JAMA psychiatry.

[6]  M. Daly,et al.  A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population , 2019, Translational Psychiatry.

[7]  L. Petersen,et al.  Childhood infections and schizophrenia: The impact of parental SES and mental illness, and childhood adversities , 2019, Brain, Behavior, and Immunity.

[8]  O. Mors,et al.  Efficacy of anti‐inflammatory treatment on major depressive disorder or depressive symptoms: meta‐analysis of clinical trials , 2019, Acta psychiatrica Scandinavica.

[9]  R. Yolken,et al.  A Nationwide Study in Denmark of the Association Between Treated Infections and the Subsequent Risk of Treated Mental Disorders in Children and Adolescents , 2019, JAMA psychiatry.

[10]  John P. Rice,et al.  Identification of common genetic risk variants for autism spectrum disorder , 2019, Nature Genetics.

[11]  R. Yolken,et al.  Parental Infections Before, During, and After Pregnancy as Risk Factors for Mental Disorders in Childhood and Adolescence: A Nationwide Danish Study , 2019, Biological Psychiatry.

[12]  N. Wray,et al.  A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment , 2019, Nature Neuroscience.

[13]  Brielin C. Brown,et al.  Comparative genetic architectures of schizophrenia in East Asian and European populations , 2018, Nature Genetics.

[14]  Alicia R. Martin,et al.  Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder , 2018, Nature Genetics.

[15]  M. Nordentoft,et al.  Cerebrospinal fluid markers of inflammation and infections in schizophrenia and affective disorders: a systematic review and meta-analysis , 2018, Molecular Psychiatry.

[16]  Warren W. Kretzschmar,et al.  Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression , 2017, Nature Genetics.

[17]  Melissa J. Green,et al.  Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder , 2017, bioRxiv.

[18]  M. Daly,et al.  The iPSYCH2012 case–cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders , 2017, Molecular Psychiatry.

[19]  O. Mors,et al.  Influence of Polygenic Risk Scores on the Association Between Infections and Schizophrenia , 2016, Biological Psychiatry.

[20]  Giulio Genovese,et al.  Schizophrenia risk from complex variation of complement component 4 , 2016, Nature.

[21]  P. Visscher,et al.  Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores , 2015, bioRxiv.

[22]  P. Mortensen,et al.  Somatic diseases and conditions before the first diagnosis of schizophrenia: a nationwide population-based cohort study in more than 900 000 individuals. , 2015, Schizophrenia bulletin.

[23]  P. Mortensen,et al.  Hospital contacts with infection and risk of schizophrenia: a population-based cohort study with linkage of Danish national registers. , 2014, Schizophrenia bulletin.

[24]  B. Berger,et al.  Efficient Bayesian mixed model analysis increases association power in large cohorts , 2014, Nature Genetics.

[25]  C. Spencer,et al.  Biological Insights From 108 Schizophrenia-Associated Genetic Loci , 2014, Nature.

[26]  P. Mortensen,et al.  Autoimmune diseases and severe infections as risk factors for mood disorders: a nationwide study. , 2013, JAMA psychiatry.

[27]  C. Correll,et al.  The validity of the schizophrenia diagnosis in the Danish Psychiatric Central Research Register is good. , 2013, Danish medical journal.

[28]  D. Schendel,et al.  Autism After Infection, Febrile Episodes, and Antibiotic Use During Pregnancy: An Exploratory Study , 2012, Pediatrics.

[29]  D. Schendel,et al.  Using maternally reported data to investigate the association between early childhood infection and autism spectrum disorder: the importance of data source. , 2012, Paediatric and perinatal epidemiology.

[30]  P. Mortensen,et al.  Autoimmune diseases and severe infections as risk factors for schizophrenia: a 30-year population-based register study. , 2011, The American journal of psychiatry.

[31]  R. Duggirala,et al.  Genetic Factors Influence Serological Measures of Common Infections , 2011, Human Heredity.

[32]  O. Mors,et al.  The Danish Psychiatric Central Research Register , 2011, Scandinavian journal of public health.

[33]  C. Pedersen,et al.  The Danish Civil Registration System , 2011, Scandinavian journal of public health.

[34]  Elsebeth Lynge,et al.  The Danish National Patient Register , 2011, Scandinavian journal of public health.

[35]  D. Schendel,et al.  Association of hospitalization for infection in childhood with diagnosis of autism spectrum disorders: a Danish cohort study. , 2010, Archives of pediatrics & adolescent medicine.

[36]  M. Lipsitch,et al.  Negative Controls: A Tool for Detecting Confounding and Bias in Observational Studies , 2010, Epidemiology.

[37]  D. Hougaard,et al.  Storage policies and use of the Danish Newborn Screening Biobank , 2007, Journal of Inherited Metabolic Disease.

[38]  B. Nordestgaard,et al.  Influence of diabetes and hyperglycaemia on infectious disease hospitalisation and outcome , 2007, Diabetologia.

[39]  Michael K Parides,et al.  Separation of individual‐level and cluster‐level covariate effects in regression analysis of correlated data , 2003, Statistics in medicine.

[40]  P. Andersen,et al.  Effects of family history and place and season of birth on the risk of schizophrenia. , 1999, The New England journal of medicine.

[41]  H. Dorn,et al.  Manual of the International Statistical Classification of Diseases, Injuries and Causes of Death. Vol. I , 1950 .

[42]  L. Petersen,et al.  Joint Effects of Exposure to Prenatal Infection and Peripubertal Psychological Trauma in Schizophrenia , 2017, Schizophrenia bulletin.

[43]  P. Mortensen,et al.  Association between parental hospital-treated infection and the risk of schizophrenia in adolescence and early adulthood. , 2013, Schizophrenia bulletin.

[44]  L. Guralnick.  Manual of the International Statistical Classification of Diseases, Injuries, and Causes of Death: World Health Organization, Vol. 1. xli + 393 pages, 1957, $6.75 (2-vol. set price) , 1959 .