Edible nuts and metabolic health

Purpose of review This review summarizes evidence for metabolic health benefits of tree nuts and groundnuts (peanuts). While a role for nuts in the dietary management of LDL-cholesterol is well established, it is evident that regular consumption of nuts may also help to counteract other cardiovascular and metabolic risk factors. Recent findings Nuts are not only energy dense foods, they are rich sources of monounsaturated and polyunsaturated fatty acids and other bioactive nutrients with important metabolic effects. Contrary to expectations, epidemiological studies indicate that regular consumption of nuts is unlikely to contribute to obesity or increased risk of diabetes. In fact, it may help to regulate body weight by suppressing appetite and fat absorption. Nut consumption counteracts dyslipidemia and has the capacity to improve circulatory function through the actions of multiple constituents (arginine, polyphenols) on endothelial mechanisms. Summary Nuts are densely packaged nutrients with wide-ranging cardiovascular and metabolic benefits, which can be readily incorporated in healthy diets. Their potential role in counteracting obesity and the metabolic syndrome warrants further investigation.

[1]  P. Kris-Etherton,et al.  Tree nuts and the lipid profile: a review of clinical studies , 2006, British Journal of Nutrition.

[2]  R. Mattes,et al.  Applied nutritional investigation Effects of peanut oil load on energy expenditure, body composition, lipid profile, and appetite in lean and overweight adults , 2006 .

[3]  I. Raskin,et al.  Effects of Arachis hypogaea nutshell extract on lipid metabolic enzymes and obesity parameters. , 2006, Life sciences.

[4]  A. Koçyiğit,et al.  Effects of pistachio nuts consumption on plasma lipid profile and oxidative status in healthy volunteers. , 2006, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[5]  J. B. Monteiro,et al.  Effects of peanut oil consumption on appetite and food choice , 2006, International Journal of Obesity.

[6]  M. Ravier,et al.  Dual mechanism of the potentiation by glucose of insulin secretion induced by arginine and tolbutamide in mouse islets. , 2006, American journal of physiology. Endocrinology and metabolism.

[7]  G. Valacchi,et al.  Walnuts reduce aortic ET-1 mRNA levels in hamsters fed a high-fat, atherogenic diet. , 2006, The Journal of nutrition.

[8]  R. Kronmal,et al.  Nut and seed consumption and inflammatory markers in the multi-ethnic study of atherosclerosis. , 2006, American journal of epidemiology.

[9]  J. Chin-Dusting,et al.  AMINO ACIDS, ARGINASE AND NITRIC OXIDE IN VASCULAR HEALTH , 2006, Clinical and experimental pharmacology & physiology.

[10]  J. Manson,et al.  Adherence to the Mediterranean dietary pattern is positively associated with plasma adiponectin concentrations in diabetic women. , 2006, The American journal of clinical nutrition.

[11]  C. Johnston,et al.  Vinegar and peanut products as complementary foods to reduce postprandial glycemia. , 2005, Journal of the American Dietetic Association.

[12]  D. Jump,et al.  Fatty acid regulation of hepatic gene transcription. , 2005, The Journal of nutrition.

[13]  M. Zibaeenezhad,et al.  Walnut Consumption in Hyperlipidemic Patients , 2005, Angiology.

[14]  J. Mukuddem-Petersen,et al.  A systematic review of the effects of nuts on blood lipid profiles in humans. , 2005, The Journal of nutrition.

[15]  J. Mann,et al.  Cholesterol lowering effects of nuts compared with a Canola oil enriched cereal of similar fat composition. , 2005, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[16]  B. Tamizifar,et al.  A LOW-DOSE ALMOND-BASED DIET DECREASES LDL-C WHILE PRESERVING HDL-C , 2005 .

[17]  M. St-Onge Dietary fats, teas, dairy, and nuts: potential functional foods for weight control? , 2005, The American journal of clinical nutrition.

[18]  C. Johnston,et al.  Oxidation of ascorbic acid in stored orange juice is associated with reduced plasma vitamin C concentrations and elevated lipid peroxides. , 2005, Journal of the American Dietetic Association.

[19]  O. Franco,et al.  The Polymeal: a more natural, safer, and probably tastier (than the Polypill) strategy to reduce cardiovascular disease by more than 75% , 2004, BMJ : British Medical Journal.

[20]  R. Marfella,et al.  Effect of a mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trial. , 2004, JAMA.

[21]  J. Connell,et al.  The role of insulin and the adipocytokines in regulation of vascular endothelial function. , 2004, Clinical science.

[22]  P. Kris-Etherton,et al.  Dietary α-Linolenic Acid Reduces Inflammatory and Lipid Cardiovascular Risk Factors in Hypercholesterolemic Men and Women , 2004 .

[23]  V. Schini-Kerth,et al.  Vascular protection by dietary polyphenols. , 2004, European journal of pharmacology.

[24]  Huiqing Yuan,et al.  Polyphenols from peanut skins and their free radical-scavenging effects. , 2004, Phytochemistry.

[25]  S. French Effects of dietary fat and carbohydrate on appetite vary depending upon site and structure , 2004, British Journal of Nutrition.

[26]  N. O'Brien,et al.  Fatty acid profile, tocopherol, squalene and phytosterol content of walnuts, almonds, peanuts, hazelnuts and the macadamia nut , 2004, International journal of food sciences and nutrition.

[27]  E. Ros,et al.  A Walnut Diet Improves Endothelial Function in Hypercholesterolemic Subjects: A Randomized Crossover Trial , 2004, Circulation.

[28]  J. Sabate,et al.  Almonds vs complex carbohydrates in a weight reduction program , 2004, International Journal of Obesity.

[29]  R. Ostlund Phytosterols and cholesterol metabolism , 2004, Current opinion in lipidology.

[30]  P. Kris-Etherton,et al.  Effects of moderate-fat (from monounsaturated fat) and low-fat weight-loss diets on the serum lipid profile in overweight and obese men and women. , 2004, The American journal of clinical nutrition.

[31]  Claude Lenfant,et al.  Definition of Metabolic Syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on Scientific Issues Related to Definition , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[32]  P. Kris-Etherton,et al.  Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women. , 2004, The Journal of nutrition.

[33]  J. Sabaté Nut consumption and body weight. , 2003, The American journal of clinical nutrition.

[34]  P. Garcia-Lorda,et al.  Nut consumption, body weight and insulin resistance , 2003, European Journal of Clinical Nutrition.

[35]  J. Brand-Miller,et al.  The degree of fat saturation does not alter glycemic, insulinemic or satiety responses to a starchy staple in healthy men. , 2003, The Journal of nutrition.

[36]  R. Mattes,et al.  Peanut Consumption Improves Indices of Cardiovascular Disease Risk in Healthy Adults , 2003, Journal of the American College of Nutrition.

[37]  Walter C Willett,et al.  Nut and peanut butter consumption and risk of type 2 diabetes in women. , 2002, JAMA.

[38]  Andrea Bonanome,et al.  Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. , 2002, The American journal of medicine.

[39]  J. Rood,et al.  Effect of diets enriched in almonds on insulin action and serum lipids in adults with normal glucose tolerance or type 2 diabetes. , 2002, The American journal of clinical nutrition.

[40]  R. Mattes,et al.  Effects of chronic peanut consumption on energy balance and hedonics , 2002, International Journal of Obesity.

[41]  J. Sabaté,et al.  Effect on Body Weight of a Free 76 Kilojoule (320 Calorie) Daily Supplement of Almonds for Six Months , 2002, Journal of the American College of Nutrition.

[42]  B. Schneeman,et al.  Almonds and almond oil have similar effects on plasma lipids and LDL oxidation in healthy men and women. , 2002, The Journal of nutrition.

[43]  A. Folsom,et al.  Frequent nut intake and risk of death from coronary heart disease and all causes in postmenopausal women: the Iowa Women's Health Study. , 2001, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[44]  F. Sacks,et al.  A randomized controlled trial of a moderate-fat, low-energy diet compared with a low fat, low-energy diet for weight loss in overweight adults , 2001, International Journal of Obesity.

[45]  M. Westerterp-Plantenga,et al.  Fat-specific satiety in humans for fat high in linoleic acid vs fat high in oleic acid , 2001, European Journal of Clinical Nutrition.

[46]  F. Hu,et al.  Dietary modulation of endothelial function: implications for cardiovascular disease. , 2001, The American journal of clinical nutrition.

[47]  J. Manson,et al.  Types of Dietary Fat and Risk of Coronary Heart Disease: A Critical Review , 2001, Journal of the American College of Nutrition.

[48]  T. Sanders,et al.  Occurrence of resveratrol in edible peanuts. , 2000, Journal of agricultural and food chemistry.

[49]  P. Kris-Etherton,et al.  High-monounsaturated fatty acid diets lower both plasma cholesterol and triacylglycerol concentrations. , 1999, The American journal of clinical nutrition.

[50]  P. Kris-Etherton,et al.  Nuts and their bioactive constituents: effects on serum lipids and other factors that affect disease risk. , 1999, The American journal of clinical nutrition.

[51]  J. Sabaté Nut consumption, vegetarian diets, ischemic heart disease risk, and all-cause mortality: evidence from epidemiologic studies. , 1999, American Journal of Clinical Nutrition.

[52]  J. Manson,et al.  Frequent nut consumption and risk of coronary heart disease in women: prospective cohort study , 1998, BMJ.

[53]  D. Knauft,et al.  Low fat-monounsaturated rich diets containing high-oleic peanuts improve serum lipoprotein profiles , 1997, Lipids.

[54]  R. Bergman,et al.  Dietary fat and insulin sensitivity in a triethnic population: the role of obesity. The Insulin Resistance Atherosclerosis Study (IRAS) , 1997, The American journal of clinical nutrition.

[55]  M. Gorman,et al.  Position of The American Dietetic Association: health implications of dietary fiber. , 1993, Journal of the American Dietetic Association.

[56]  J. Sabaté,et al.  A possible protective effect of nut consumption on risk of coronary heart disease. The Adventist Health Study. , 1992, Archives of internal medicine.

[57]  S. Grundy,et al.  Comparison of a high-carbohydrate diet with a high-monounsaturated-fat diet in patients with non-insulin-dependent diabetes mellitus. , 1988, The New England journal of medicine.