Cytosolic drug delivery using pH- and light-sensitive liposomes.

[1]  N. Wymer,et al.  Intracellular Delivery of Liposomal Contents Using pH-and Light-Activated Plasmenyl-Type Liposomes , 1999 .

[2]  D. Thompson,et al.  Synthesis of acid-labile diplasmenyl lipids for drug and gene delivery applications. , 1999, Chemistry and physics of lipids.

[3]  P. Low,et al.  Diplasmenylcholine−Folate Liposomes: An Efficient Vehicle for Intracellular Drug Delivery† , 1998 .

[4]  David H. Thompson,et al.  Cascade liposomal triggering: light-induced Ca2+ release from diplasmenylcholine liposomes triggers PLA2-catalyzed hydrolysis and contents leakage from DPPC liposomes. , 1998, Bioconjugate chemistry.

[5]  A. Moor,et al.  In vitro Fluence Rate Effects in Photodynamic Reactions with AIPcS4 as Sensitizer , 1997, Photochemistry and photobiology.

[6]  A. Scherz,et al.  Protein‐A‐mediated Targeting of Bacteriochlorophyll‐IgG to Staphylococcus aureus: A Model for Enhanced Site‐Specific Photocytotoxicity , 1997, Photochemistry and photobiology.

[7]  Ichiro Okura,et al.  Photodynamic Efficiency of Protoporphyrin IX: Comparison of Endogenous Protoporphyrin IX Induced by 5‐Aminolevulinic Acid and Exogenous Porphyrin IX , 1997 .

[8]  Thomas Boehm,et al.  Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance , 1997, Nature.

[9]  J. Behr,et al.  In vitro gene delivery to hepatocytes with galactosylated polyethylenimine. , 1997, Bioconjugate chemistry.

[10]  J. Wilschut,et al.  Membrane fusion activity of Semliki Forest virus in a liposomal model system: specific inhibition by Zn2+ ions. , 1997, Virology.

[11]  C. Benz,et al.  Anti-HER2 immunoliposomes for targeted therapy of human tumors. , 1997, Cancer letters.

[12]  M. Vicente,et al.  Meso‐Tetraphenylporphyrin Dimer Derivative as a Potential Photosensitizer in Photodynamic Therapy , 1997, Photochemistry and photobiology.

[13]  F. Goñi,et al.  Permeabilization and fusion of uncharged lipid vesicles induced by the HIV-1 fusion peptide adopting an extended conformation: dose and sequence effects. , 1997, Biophysical journal.

[14]  T. Salditt,et al.  TWO-DIMENSIONAL SMECTIC ORDERING OF LINEAR DNA CHAINS IN SELF-ASSEMBLED DNA-CATIONIC LIPOSOME MIXTURES , 1997 .

[15]  M. Bally,et al.  Influence of pH gradients on the transbilayer transport of drugs, lipids, peptides and metal ions into large unilamellar vesicles. , 1997, Biochimica et biophysica acta.

[16]  R. Schiffelers,et al.  Human recombinant apolipoprotein E-enriched liposomes can mimic low-density lipoproteins as carriers for the site-specific delivery of antitumor agents. , 1997, Molecular pharmacology.

[17]  M. Soncin,et al.  Pharmacokinetic and phototherapeutic properties of axially substituted Si(IV)-tetradibenzobarreleno-octabutoxyphthalocyanines. , 1997, Journal of photochemistry and photobiology. B, Biology.

[18]  C. Gomer,et al.  Increased Photosensitivity in HL60 Cells Expressing Wild‐Type p53 , 1997, Photochemistry and photobiology.

[19]  F. West,et al.  Sonolysis promotes indirect Co-C bond cleavage of alkylcob(III)alamin bioconjugates. , 1997, Bioconjugate chemistry.

[20]  A. Alonso,et al.  Poly(ethylene glycol)‐lipid conjugates inhibit phospholipase C‐induced lipid hydrolysis, liposome aggregation and fusion through independent mechanisms , 1997, FEBS letters.

[21]  J. A. Jaeger,et al.  Oligonucleotide Pharmacology and Formulation: G3139 Anti-BCL2 Phosphorothioate In Stealth® Liposomes and Gel Implants , 1997 .

[22]  S. Hui,et al.  Effects of lipid headgroup and packing stress on poly(ethylene glycol)-induced phospholipid vesicle aggregation and fusion. , 1997, Biophysical journal.

[23]  R. Epand,et al.  Structural study of the relationship between the rate of membrane fusion and the ability of the fusion peptide of influenza virus to perturb bilayers. , 1997, Biochemistry.

[24]  K. Kono,et al.  Cytoplasmic delivery of calcein mediated by liposomes modified with a pH-sensitive poly(ethylene glycol) derivative. , 1997, Biochimica et biophysica acta.

[25]  M. Bally,et al.  Influence of drug release characteristics on the therapeutic activity of liposomal mitoxantrone. , 1997, The Journal of pharmacology and experimental therapeutics.

[26]  R. Blumenthal,et al.  Solubilization and reconstitution of vesicular stomatitis virus envelope using octylglucoside. , 1997, Biophysical journal.

[27]  J. Philippot,et al.  Membrane anchorage brings about fusogenic properties in a short synthetic peptide. , 1997, Biochemistry.

[28]  P. Cullis,et al.  pH-induced destabilization of lipid bilayers by a lipopeptide derived from influenza hemagglutinin. , 1997, Biochimica et biophysica acta.

[29]  A. Schwan,et al.  Acid-catalyzed plasmenylcholine hydrolysis and its effect on bilayer permeability: a quantitative study. , 1997, Biochimica et biophysica acta.

[30]  F. Szoka,et al.  Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. , 1997, Biochemistry.

[31]  Mehmet Toner,et al.  Reversible permeabilization of plasma membranes with an engineered switchable pore , 1997, Nature Biotechnology.

[32]  D. Hoekstra,et al.  Novel pyridinium surfactants for efficient, nontoxic in vitro gene delivery. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[33]  P. Cullis,et al.  Membrane fusion with cationic liposomes: effects of target membrane lipid composition. , 1997, Biochemistry.

[34]  Joachim O. Rädler,et al.  Structure of DNA-Cationic Liposome Complexes: DNA Intercalation in Multilamellar Membranes in Distinct Interhelical Packing Regimes , 1997, Science.

[35]  S. Simões,et al.  Sterically Stabilized pH-sensitive Liposomes , 1997, The Journal of Biological Chemistry.

[36]  J. Behr,et al.  Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold. , 1996, Gene therapy.

[37]  Y. Yarden,et al.  Targeting of stealth liposomes to erbB-2 (Her/2) receptor: in vitro and in vivo studies. , 1996, British Journal of Cancer.

[38]  F. Szoka,et al.  Effect of cholesterol and charge on pore formation in bilayer vesicles by a pH-sensitive peptide. , 1996, Biophysical journal.

[39]  E. Brambilla,et al.  An electron microscopy study into the mechanism of gene transfer with lipopolyamines. , 1996, Gene therapy.

[40]  M. Ruiz-Argüello,et al.  Different Effects of Enzyme-generated Ceramides and Diacylglycerols in Phospholipid Membrane Fusion and Leakage* , 1996, The Journal of Biological Chemistry.

[41]  J. Hendriks,et al.  Targeted delivery of diphtheria toxin via immunoliposomes: efficient antitumor activity in the presence of inactivating anti‐diphtheria toxin antibodies , 1996, FEBS letters.

[42]  C. Benoist,et al.  A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: polyethylenimine. , 1996, Human gene therapy.

[43]  F. Szoka,et al.  Mechanism of oligonucleotide release from cationic liposomes. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[44]  M. Andreeff,et al.  Cellular uptake and localization of liposomal-methylphosphonate oligodeoxynucleotides , 1996, Journal of Molecular Medicine.

[45]  P. Steerenberg,et al.  Immunoliposome-mediated targeting of doxorubicin to human ovarian carcinoma in vitro and in vivo. , 1996, British Journal of Cancer.

[46]  H. Wu,et al.  A slight asymmetry in the transbilayer distribution of lysophosphatidylcholine alters the surface properties and poly(ethylene glycol)-mediated fusion of dipalmitoylphosphatidylcholine large unilamellar vesicles. , 1996, Biochemistry.

[47]  E. Moase,et al.  Therapeutic opportunities for targeted liposomal drug delivery , 1996 .

[48]  F. Szoka,et al.  Liposomes as a carrier for intracellular delivery of antisense oligonucleotides: a real or magic bullet? , 1996 .

[49]  J. Dijkstra,et al.  Activation of murine lymphocytes by lipopolysaccharide incorporated in fusogenic, reconstituted influenza virus envelopes (virosomes). , 1996, Journal of immunology.

[50]  J. Wilschut,et al.  Fusion of reconstituted influenza virus envelopes with liposomes mediated by streptavidin/biotin interactions , 1996, FEBS letters.

[51]  H. Bayley,et al.  Tumor protease-activated, pore-forming toxins from a combinatorial library , 1996, Nature Biotechnology.

[52]  F. Sorgi,et al.  In vivo cytokine gene therapy of human tumor xenografts in SCID mice by liposome-mediated DNA delivery. , 1996, Gene therapy.

[53]  T. Allen,et al.  Use of targeted cationic liposomes in enhanced DNA delivery to cancer cells. , 1996, Cancer gene therapy.

[54]  Samuel Zalipsky,et al.  Liposomes with detachable polymer coating: destabilization and fusion of dioleoylphosphatidylethanolamine vesicles triggered by cleavage of surface‐grafted poly(ethylene glycol) , 1996, FEBS letters.

[55]  F. Goñi,et al.  Dual inhibitory effect of gangliosides on phospholipase C-promoted fusion of lipidic vesicles. , 1996, Biochemistry.

[56]  J. Hagstrom,et al.  pH-sensitive, cationic liposomes: A new synthetic virus-like vector , 1996, Nature Biotechnology.

[57]  I. Saiki,et al.  Liposomal Arg-Gly-Asp analogs effectively inhibit metastatic B16 melanoma colonization in murine lungs. , 1996, Life sciences.

[58]  F. Szoka,et al.  Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. , 1996, Biochemistry.

[59]  G. Jori,et al.  Liposome‐Mediated Delivery of Photosensitizers: Localization of Zinc (11)‐Phthalocyanine within Implanted Tumors after Intravenous Administration , 1996, Photochemistry and photobiology.

[60]  B. Tromberg,et al.  Fluorescence imaging studies for the disposition of daunorubicin liposomes (DaunoXome) within tumor tissue. , 1996, Cancer research.

[61]  Leaf Huang,et al.  DC-Chol lipid system in gene transfer , 1996 .

[62]  Leaf Huang,et al.  Folate-targeted, Anionic Liposome-entrapped Polylysine-condensed DNA for Tumor Cell-specific Gene Transfer (*) , 1996, The Journal of Biological Chemistry.

[63]  K. Kono,et al.  Temperature-controlled release property of phospholipid vesicles bearing a thermo-sensitive polymer. , 1996, Biochimica et biophysica acta.

[64]  P. Felgner,et al.  Converting an alcohol to an amine in a cationic lipid dramatically alters the co-lipid requirement, cellular transfection activity and the ultrastructure of DNA-cytofectin complexes. , 1996, Biochimica et biophysica acta.

[65]  Yingxian Fu,et al.  Singlet‐Oxygen Generation from Liposomes: A Comparison of 6β‐Cholesterol Hydroperoxide Formation with Predictions from a One‐Dimensional Model of Singlet‐Oxygen Diffusion and Quenching , 1996 .

[66]  E. Reddi,et al.  Interaction of hydro- or lipophilic phthalocyanines with cells of different metastatic potential. , 1996, Biochemical pharmacology.

[67]  Shai Rubin,et al.  Control of the Structure and Functions of Biomaterials by Light , 1996 .

[68]  P. Cullis,et al.  Poly(ethylene glycol)--lipid conjugates regulate the calcium-induced fusion of liposomes composed of phosphatidylethanolamine and phosphatidylserine. , 1996, Biochemistry.

[69]  D. Thompson,et al.  Triggerable plasmalogen liposomes: improvement of system efficiency. , 1996, Biochimica et biophysica acta.

[70]  M. Soncin,et al.  Effect of Photosensitizer Delivery System and Irradiation Parameters on the Efficiency of Photodynamic Therapy of B16 Pigmented Melanoma in Mice , 1996, Photochemistry and photobiology.

[71]  Leaf Huang,et al.  Potentiation of cationic liposome-mediated gene delivery by polycations. , 1996, Biochemistry.

[72]  J. Ruysschaert,et al.  Structural study of the interaction between the SIV fusion peptide and model membranes. , 1996, Biochemistry.

[73]  D. Tirrell,et al.  Kinetics of membrane micellization by the hydrophobic polyelectrolyte poly(2-ethylacrylic acid). , 1996, Biochimica et biophysica acta.

[74]  P. Couvreur,et al.  Retrovirus budding may constitute a port of entry for drug carriers. , 1996, Biochimica et biophysica acta.

[75]  T. Mayumi,et al.  Efficient gene transfer into mammalian cells using fusogenic liposome. , 1996, Biochemical and biophysical research communications.

[76]  David E. Housman,et al.  Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours , 1996, Nature.

[77]  H. Farhood,et al.  Endosomolytic activity of cationic liposomes enhances the delivery of human immunodeficiency virus-1 trans-activator protein (TAT) to mammalian cells. , 1995, Biochemical and biophysical research communications.

[78]  S. Lesieur,et al.  Partition coefficient of a surfactant between aggregates and solution: application to the micelle-vesicle transition of egg phosphatidylcholine and octyl beta-D-glucopyranoside. , 1995, Biophysical journal.

[79]  F S Cohen,et al.  Membrane mechanics can account for fusion pore dilation in stages. , 1995, Biophysical journal.

[80]  I. Ahmad,et al.  Immunoliposome-mediated targeting of anti-cancer drugs in vivo. , 1995, Biochemical Society transactions.

[81]  N. Caplen,et al.  In vitro liposome-mediated DNA transfection of epithelial cell lines using the cationic liposome DC-Chol/DOPE. , 1995, Gene therapy.

[82]  Y. Shai Molecular recognition between membrane-spanning polypeptides. , 1995, Trends in biochemical sciences.

[83]  R. Ralhan,et al.  Heat-mediated selective delivery of liposomeassociated melphalan in murine melanoma , 1995, Melanoma research.

[84]  J. Parra,et al.  Interaction of anionic/nonionic surfactant mixtures with phosphatidylcholine liposomes. , 1995, Archives of biochemistry and biophysics.

[85]  K. König,et al.  Cell damage by near-IR microbeams , 1995, Nature.

[86]  J. Zimmerberg,et al.  The hemifusion intermediate and its conversion to complete fusion: regulation by membrane composition. , 1995, Biophysical journal.

[87]  T. Meade,et al.  Transfection of folate-polylysine DNA complexes: evidence for lysosomal delivery. , 1995, Bioconjugate chemistry.

[88]  R. Bittman,et al.  Sphingolipids activate membrane fusion of Semliki Forest virus in a stereospecific manner. , 1995, Biochemistry.

[89]  D. Scherman,et al.  A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[90]  T. Allen,et al.  A new strategy for attachment of antibodies to sterically stabilized liposomes resulting in efficient targeting to cancer cells. , 1995, Biochimica et biophysica acta.

[91]  M. Woodle,et al.  Pharmacokinetics and anti‐tumor activity of vincristine encapsulated in sterically stabilized liposomes , 1995, International journal of cancer.

[92]  T. A. Connors,et al.  The chemotherapy of colon cancer. , 1995, European journal of cancer.

[93]  H. Farhood,et al.  The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. , 1995, Biochimica et biophysica acta.

[94]  I. Wróbel,et al.  Fusion of cationic liposomes with mammalian cells occurs after endocytosis. , 1995, Biochimica et biophysica acta.

[95]  J. Behr,et al.  Efficient gene delivery with neutral complexes of lipospermine and thiol-reactive phospholipids. , 1995, Biochemical and biophysical research communications.

[96]  M. T. ten Kate,et al.  Efficacy of gentamicin or ceftazidime entrapped in liposomes with prolonged blood circulation and enhanced localization in Klebsiella pneumoniae-infected lung tissue. , 1995, The Journal of infectious diseases.

[97]  M. Bally,et al.  Pharmacology of liposomal vincristine in mice bearing L1210 ascitic and B16/BL6 solid tumours. , 1995, British Journal of Cancer.

[98]  P. Gangadharam,et al.  Therapy of Mycobacterium avium complex infections in beige mice with streptomycin encapsulated in sterically stabilized liposomes , 1995, Antimicrobial agents and chemotherapy.

[99]  J. Behr,et al.  Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage toward artificial viruses. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[100]  M. Hawthorne,et al.  Selective boron delivery to murine tumors by lipophilic species incorporated in the membranes of unilamellar liposomes. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[101]  M. Ueno,et al.  Study on hepatic artery chemoembolization using temperature-sensitive liposome or lipiodol emulsion. , 1995, Biological and Pharmaceutical Bulletin.

[102]  R. Malone,et al.  Cholesterol enhances cationic liposome-mediated DNA transfection of human respiratory epithelial cells , 1995, Bioscience reports.

[103]  D. Crommelin,et al.  Adhesion molecules: a new target for immunoliposome‐mediated drug delivery , 1995, FEBS letters.

[104]  P. Oh,et al.  Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules , 1994, The Journal of cell biology.

[105]  T. Akao,et al.  Design of a new cationic amphiphile with efficient DNA-transfection ability. , 1994, Biochemistry and molecular biology international.

[106]  R. Margalit,et al.  Molecular and cellular studies of hyaluronic acid-modified liposomes as bioadhesive carriers for topical drug delivery in wound healing. , 1994, Archives of biochemistry and biophysics.

[107]  A. Ashkenazi,et al.  Liposome targeting to human immunodeficiency virus type 1-infected cells via recombinant soluble CD4 and CD4 immunoadhesin (CD4-IgG). , 1994, Biochimica et biophysica acta.

[108]  Jizomoto Hiroaki,et al.  pH-Sensitive liposomes composed of tocopherol hemisuccinate and of phosphatidylethanolamine including tocopherol hemisuccinate , 1994 .

[109]  A. Deisseroth,et al.  Liposomal delivery of methylphosphonate antisense oligodeoxynucleotides in chronic myelogenous leukemia. , 1994, Blood.

[110]  G. Hahn,et al.  Hyperthermia induces doxorubicin release from long-circulating liposomes and enhances their anti-tumor efficacy. , 1994, International journal of radiation oncology, biology, physics.

[111]  J. Wilschut,et al.  Membrane fusion of Semliki Forest virus requires sphingolipids in the target membrane. , 1994, The EMBO journal.

[112]  G. Storm,et al.  Immunoliposomes in vivo. , 1994, ImmunoMethods.

[113]  M. Bally,et al.  Liposomal vincristine which exhibits increased drug retention and increased circulation longevity cures mice bearing P388 tumors. , 1994, Cancer research.

[114]  L. Huang,et al.  Liposome-mediated cytoplasmic delivery of proteins: an effective means of accessing the MHC class I-restricted antigen presentation pathway. , 1994, ImmunoMethods.

[115]  William Love,et al.  Uptake of zinc(II)-phthalocyanine by HepG2 cells expressing the low-density lipoprotein receptor: studies with the liposomal formulation CGP55847 , 1994, Other Conferences.

[116]  Ute Isele,et al.  CGP 55 847, liposome-delivered zinc(II)-phthalocyanine as a phototherapeutic agent for tumors , 1994, Other Conferences.

[117]  P. Low,et al.  Delivery of liposomes into cultured KB cells via folate receptor-mediated endocytosis. , 1994, The Journal of biological chemistry.

[118]  R. Margalit,et al.  Bioadhesive, collagen-modified liposomes: molecular and cellular level studies on the kinetics of drug release and on binding to cell monolayers. , 1994, Biochimica et biophysica acta.

[119]  B. Lentz,et al.  Poly(ethylene glycol)-induced fusion and rupture of dipalmitoylphosphatidylcholine large, unilamellar extruded vesicles. , 1993, Biochemistry.

[120]  D. Crommelin,et al.  The effect of aging on the physical stability of liposome dispersions. , 1992, Chemistry and physics of lipids.

[121]  R K Jain,et al.  Delivery of novel therapeutic agents in tumors: physiological barriers and strategies. , 1990, Journal of the National Cancer Institute.

[122]  L. J. Lis,et al.  Membrane fusion and inverted phases. , 1989, Biochemistry.

[123]  O. Eidelman,et al.  Micelle-vesicle transition of egg phosphatidylcholine and octyl glucoside. , 1988, Biochemistry.

[124]  Leaf Huang,et al.  Chapter 12 Drug Delivery Applications , 1997 .

[125]  Karl Mechtler,et al.  GENE TRANSFER MEDIATED BY INFLUENZA VIRUS PEPTIDES : THE ROLE OF PEPTIDE SEQUENCES , 1997 .

[126]  C. Benz,et al.  Targeting of Liposomes to Solid Tumors: The Case of Sterically Stabilized Anti-Her2 Immunoliposomes , 1997 .

[127]  S. Agrawal,et al.  In vivo studies with antisense oligonucleotides. , 1997, Trends in pharmacological sciences.

[128]  S. Zellmer,et al.  Tumor targeting in vivo by means of thermolabile fusogenic liposomes. , 1996, Journal of drug targeting.

[129]  D. Thompson,et al.  TRIGGERED RELEASE FROM LIPOSOMES MEDIATED BY PHYSICALLY AND CHEMICALLY INDUCED PHASE TRANSITIONS , 1996 .

[130]  A. Deisseroth,et al.  Liposomal delivery of oligodeoxynucleotides. , 1996, Leukemia & lymphoma.

[131]  I. Mellman Endocytosis and molecular sorting. , 1996, Annual review of cell and developmental biology.

[132]  R. Ranju,et al.  Enhanced Antitumor Effect of Radiation in Combination with Heat-Sensitive Liposome-Encapsulated Drug and Hyperthermia on Murine Tumors , 1995 .

[133]  R. Ralhan,et al.  Hyperthermia-mediated targeted delivery of thermosensitive liposome-encapsulated melphalan in murine tumors. , 1995, Oncology research.

[134]  P. Cullis,et al.  Recent advances in liposomal drug-delivery systems. , 1995, Current opinion in biotechnology.

[135]  D. Hammer,et al.  Micropipette manipulation technique for the monitoring of pH-dependent membrane lysis as induced by the fusion peptide of influenza virus. , 1995, Biophysical journal.

[136]  Francis C. Szoka,et al.  pH-Sensitive Liposomes , 1994 .

[137]  G. Scherphof,et al.  Release of Active Drug from Intracellular Liposomal Prodrug Depots in Macrophages Controlled by Liposome Composition , 1994 .

[138]  Dexi Liu Enzyme-Controlled Release with Liposomes , 1994 .

[139]  Leaf Huang Target-sensitive liposomes , 1994 .

[140]  Smadar Cohen,et al.  PULSATILE RELEASE FROM MICROENCAPSULATED LIPOSOMES , 1994 .