Simulation of lung behaviour with finite elements: influence of bio-mechanical parameters

Motivated by medical needs, we propose to simulate lung deformation and motion during respiration to track tumours. This paper presents a model of lung behaviour based on a continuous media mechanics model and solved with a finite element method. The result is a simulation of a normal breathing, matching with patient customised data. Moreover, we carried out numerical experiments to evaluate our algorithms and to measure the influence and the relevance of mechanical parameters.

[1]  Pierre-Frédéric Villard,et al.  Lung mesh generation to simulate breathing motion with a finite element method , 2004 .

[2]  D. Panescu,et al.  Optimization of cardiac defibrillation by three-dimensional finite element modeling of the human thorax , 1995, IEEE Transactions on Biomedical Engineering.

[3]  O. C. Zienkiewicz La méthode des éléments finis , 1979 .

[4]  S. Lai-Fook,et al.  Lung parenchyma described as a prestressed compressible material. , 1977, Journal of biomechanics.

[5]  J. Mead,et al.  The mechanical properties of the lungs in emphysema. , 1955, The Journal of clinical investigation.

[6]  Mark A. Lewis,et al.  The Mechanics of Lung Tissue under High-Frequency Ventilation , 2001, SIAM J. Appl. Math..

[7]  D. L. Vawter,et al.  Constitutive Equation of Lung Tissue Elasticity , 1979 .

[8]  J. C. Simo,et al.  Associated coupled thermoplasticity at finite strains: formulation, numerical analysis and implementation , 1992 .

[9]  Pierre-Frédéric Villard,et al.  Towards accurate tumour tracking in lungs , 2003, Proceedings on Seventh International Conference on Information Visualization, 2003. IV 2003..

[10]  J. Lyszczarz,et al.  [Mechanical properties of the lungs]. , 1971, Acta physiologica Polonica.

[11]  Pierre-Frédéric Villard,et al.  Lung mesh generation to simulate breathing motion with a finite element method , 2004, Proceedings. Eighth International Conference on Information Visualisation, 2004. IV 2004..

[12]  Andy Adler,et al.  Electrical impedance tomography: regularized imaging and contrast detection , 1996, IEEE Trans. Medical Imaging.

[13]  K. Langen,et al.  Organ motion and its management. , 2001, International journal of radiation oncology, biology, physics.

[14]  F L Matthews,et al.  Stresses, strains, and surface pressures in the lung caused by its weight. , 1972, Journal of applied physiology.

[15]  T A Wilson,et al.  A model for the elastic properties of the lung and their effect of expiratory flow. , 1973, Journal of applied physiology.