Mechanisms of Resistance in Multiple-Antibiotic-Resistant Escherichia coli Strains of Human, Animal, and Food Origins

ABSTRACT Seventeen multiple-antibiotic-resistant nonpathogenic Escherichia coli strains of human, animal, and food origins showed a wide variety of antibiotic resistance genes, many of them carried by class 1 and class 2 integrons. Amino acid changes in MarR and mutations in marO were identified for 15 and 14 E. coli strains, respectively.

[1]  G. Kronvall,et al.  Sulphonamide resistance gene sul3 found in Escherichia coli isolates from human sources. , 2003, The Journal of antimicrobial chemotherapy.

[2]  Chul Hee Choi,et al.  Changes in Gene Cassettes of Class 1 Integrons among Escherichia coli Isolates from Urine Specimens Collected in Korea during the Last Two Decades , 2003, Journal of Clinical Microbiology.

[3]  J. Harel,et al.  Antimicrobial Resistance Genes in Enterotoxigenic Escherichia coli O149:K91 Isolates Obtained over a 23-Year Period from Pigs , 2003, Antimicrobial Agents and Chemotherapy.

[4]  B. Malorny,et al.  Phenotypic and genotypic characterization of antimicrobial resistance in German Escherichia coli isolates from cattle, swine and poultry. , 2003, The Journal of antimicrobial chemotherapy.

[5]  J. Ruiz,et al.  Detection of dihydrofolate reductase genes by PCR and RFLP. , 2003, Diagnostic microbiology and infectious disease.

[6]  M. Mendoza,et al.  Virulence and antimicrobial-resistance gene profiles determined by PCR-based procedures for Salmonella isolated from samples of animal origin , 2003 .

[7]  C. Torres,et al.  Mutations in gyrA and parC genes in nalidixic acid-resistant Escherichia coli strains from food products, humans and animals. , 2003, The Journal of antimicrobial chemotherapy.

[8]  V. Perreten,et al.  A New Sulfonamide Resistance Gene (sul3) in Escherichia coli Is Widespread in the Pig Population of Switzerland , 2003, Antimicrobial Agents and Chemotherapy.

[9]  G. Prats,et al.  Estructura y función de los integrones , 2002 .

[10]  C. Torres,et al.  Antibiotic resistance in Escherichia coli isolates obtained from animals, foods and humans in Spain. , 2001, International journal of antimicrobial agents.

[11]  P. White,et al.  Integrons and Gene Cassettes in theEnterobacteriaceae , 2001, Antimicrobial Agents and Chemotherapy.

[12]  A. Oliver,et al.  Characterization of Clinical Isolates ofKlebsiella pneumoniae from 19 Laboratories Using the National Committee for Clinical Laboratory Standards Extended-Spectrum β-Lactamase Detection Methods , 2001, Journal of Clinical Microbiology.

[13]  G. Eliopoulos,et al.  Resistance to trimethoprim-sulfamethoxazole. , 2001, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[14]  A. Carattoli.  Importance of integrons in the diffusion of resistance. , 2001, Veterinary research.

[15]  L. Dijkshoorn,et al.  Distribution and in-vitro transfer of tetracycline resistance determinants in clinical and aquatic Acinetobacter strains. , 2000, Journal of medical microbiology.

[16]  F. Aarestrup,et al.  Characterisation of streptomycin resistance determinants in Danish isolates of Salmonella Typhimurium. , 2000, Veterinary microbiology.

[17]  D. Mazel,et al.  Antibiotic Resistance in the ECOR Collection: Integrons and Identification of a Novel aad Gene , 2000, Antimicrobial Agents and Chemotherapy.

[18]  L. Ng,et al.  Genetic Characterization of Antimicrobial Resistance in Canadian Isolates of Salmonella Serovar Typhimurium DT104 , 1999, Antimicrobial Agents and Chemotherapy.

[19]  J. Ruiz,et al.  Increase in incidence of resistance to ampicillin, chloramphenicol and trimethoprim in clinical isolates of Salmonella serotype Typhimurium with investigation of molecular epidemiology and mechanisms of resistance. , 1999, Journal of medical microbiology.

[20]  Jin-Hong Yoo,et al.  Molecular analysis of fluoroquinolone-resistance in Escherichia coli on the aspect of gyrase and multiple antibiotic resistance (mar) genes. , 1998, Yonsei medical journal.

[21]  J. Pitout,et al.  β-Lactamases Responsible for Resistance to Expanded-Spectrum Cephalosporins in Klebsiella pneumoniae, Escherichia coli, and Proteus mirabilis Isolates Recovered in South Africa , 1998, Antimicrobial Agents and Chemotherapy.

[22]  R. Gautom.  Rapid pulsed-field gel electrophoresis protocol for typing of Escherichia coli O157:H7 and other gram-negative organisms in 1 day , 1997, Journal of clinical microbiology.

[23]  S. Levy,et al.  Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon , 1997, Antimicrobial agents and chemotherapy.

[24]  R M Hall,et al.  Gene cassettes: a new class of mobile element. , 1995, Microbiology.

[25]  J. Mullins,et al.  Photonic detection of bacterial pathogens in living hosts , 1995, Molecular microbiology.

[26]  J. Rosner,et al.  Regulation of the multiple antibiotic resistance (mar) regulon by marORA sequences in Escherichia coli , 1995, Journal of bacteriology.

[27]  R M Hall,et al.  Mobile gene cassettes and integrons: capture and spread of genes by site‐specific recombination , 1995, Molecular microbiology.

[28]  G. Paul,et al.  Nucleotide sequences of the genes coding for the TEM-like beta-lactamases IRT-1 and IRT-2 (formerly called TRI-1 and TRI-2). , 1994, FEMS microbiology letters.

[29]  S. Levy,et al.  Repressor mutations in the marRAB operon that activate oxidative stress genes and multiple antibiotic resistance in Escherichia coli , 1994, Journal of bacteriology.

[30]  C. Hart,et al.  Apramycin resistance plasmids in Escherichia coli: possible transfer to Salmonella typhimurium in calves , 1992, Epidemiology and Infection.

[31]  J. Content,et al.  Identification of the aadB gene coding for the aminoglycoside-2"-O-nucleotidyltransferase, ANT(2"), by means of the polymerase chain reaction. , 1992, The Journal of antimicrobial chemotherapy.

[32]  D. Hooper,et al.  Cross-resistance to fluoroquinolones in multiple-antibiotic-resistant (Mar) Escherichia coli selected by tetracycline or chloramphenicol: decreased drug accumulation associated with membrane changes in addition to OmpF reduction , 1989, Antimicrobial Agents and Chemotherapy.

[33]  E. Scherzinger,et al.  Complete nucleotide sequence and gene organization of the broad-host-range plasmid RSF1010. , 1989, Gene.

[34]  P. Heinzel,et al.  A second streptomycin resistance gene from Streptomyces griseus codes for streptomycin-3″-phosphotransferase , 1988, Archives of Microbiology.

[35]  E. Bruck,et al.  National Committee for Clinical Laboratory Standards. , 1980, Pediatrics.

[36]  C. Torres,et al.  Mechanisms of antibiotic resistance in Escherichia coli isolates obtained from healthy children in Spain. , 2002, Microbial drug resistance.

[37]  G. Prats,et al.  [Structure and function of integrons]. , 2002, Enfermedades infecciosas y microbiologia clinica.

[38]  D. Persing,et al.  Diagnostic molecular microbiology. , 2001, Current clinical topics in infectious diseases.

[39]  P. White,et al.  Characterisation of two new gene cassettes, aadA5 and dfrA17. , 2000, FEMS microbiology letters.

[40]  Mary Jane Ferraro,et al.  Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically : approved standard , 2000 .

[41]  C. M. Collis,et al.  Antibiotic resistance in gram-negative bacteria: the role of gene cassettes and integrons. , 1998, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

[42]  J. Waitz.  Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically , 1990 .

[43]  D. Vapnek,et al.  Nucleotide sequence analysis of a gene encoding a streptomycin/spectinomycin adenylyltransferase. , 1985, Plasmid.

[44]  D. Vapnek,et al.  Nucleotide sequence analysis of a gene encoding a streptomycin/spectinomycin adenyltransferase , 1985 .