Axon guidance proteins: Novel therapeutic targets for ALS?

[1]  R. Giger,et al.  Semaphorin function in neural plasticity and disease , 2009, Current Opinion in Neurobiology.

[2]  J. Rothstein,et al.  Current hypotheses for the underlying biology of amyotrophic lateral sclerosis , 2009, Annals of neurology.

[3]  A. Kania,et al.  Specification of Motor Axon Trajectory by Ephrin-B:EphB Signaling: Symmetrical Control of Axonal Patterning in the Developing Limb , 2008, Neuron.

[4]  Anthony W. Zoghbi,et al.  The Amyotrophic Lateral Sclerosis 8 Protein VAPB Is Cleaved, Secreted, and Acts as a Ligand for Eph Receptors , 2008, Cell.

[5]  M. Wu,et al.  Galectin-1, a novel ligand of neuropilin-1, activates VEGFR-2 signaling and modulates the migration of vascular endothelial cells , 2008, Oncogene.

[6]  Xiao-Bo Liu,et al.  Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex , 2008, Proceedings of the National Academy of Sciences.

[7]  A. Canty,et al.  Molecular mechanisms of axon guidance in the developing corticospinal tract , 2008, Progress in Neurobiology.

[8]  K. Talbot,et al.  Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS , 2008, Progress in Neurobiology.

[9]  M. Lackmann,et al.  Eph, a Protein Family Coming of Age: More Confusion, Insight, or Complexity? , 2008, Science Signaling.

[10]  R. Pasterkamp,et al.  Semaphorin signaling: progress made and promises ahead. , 2008, Trends in biochemical sciences.

[11]  O. Steward,et al.  A re-assessment of the effects of a Nogo-66 receptor antagonist on regenerative growth of axons and locomotor recovery after spinal cord injury in mice , 2008, Experimental Neurology.

[12]  D. Maraganore,et al.  Beyond Parkinson Disease: Amyotrophic Lateral Sclerosis and the Axon Guidance Pathway , 2008, PloS one.

[13]  Alexander Sasha Rabchevsky,et al.  Targeting Axon Growth from Neuronal Transplants along Preformed Guidance Pathways in the Adult CNS , 2008, The Journal of Neuroscience.

[14]  W. Shoji,et al.  Position fine-tuning of caudal primary motoneurons in the zebrafish spinal cord , 2007, Development.

[15]  K. Acharya,et al.  Human angiogenin is a neuroprotective factor and amyotrophic lateral sclerosis associated angiogenin variants affect neurite extension/pathfinding and survival of motor neurons. , 2007, Human molecular genetics.

[16]  L. Robak,et al.  Mechanisms of CNS myelin inhibition: evidence for distinct and neuronal cell type specific receptor systems. , 2008, Restorative neurology and neuroscience.

[17]  Michael Primig,et al.  Gene profiling of skeletal muscle in an amyotrophic lateral sclerosis mouse model. , 2008, Physiological genomics.

[18]  S. Tågerud,et al.  Semaphorin 6C expression in innervated and denervated skeletal muscle , 2008, Journal of Molecular Histology.

[19]  M. Schachner,et al.  Development of the corticospinal tract in Semaphorin3A- and CD24-deficient mice , 2007, Neuroscience.

[20]  E. Domanitskaya,et al.  Semaphorin6A acts as a gate keeper between the central and the peripheral nervous system , 2007, Neural Development.

[21]  V. Castellani,et al.  Semaphorin and neuropilin co-expression in motoneurons sets axon sensitivity to environmental semaphorin sources during motor axon pathfinding , 2007, Development.

[22]  A. Iafrate,et al.  Angiogenin loss‐of‐function mutations in amyotrophic lateral sclerosis , 2007, Annals of neurology.

[23]  S. Tågerud,et al.  Muscle Nogo‐A: a marker for amyotrophic lateral sclerosis or for denervation? , 2007, Annals of neurology.

[24]  W. Engel,et al.  Expression of Nogo‐A in human muscle fibers is not specific for amyotrophic lateral sclerosis , 2007, Annals of neurology.

[25]  B. Fadeel,et al.  VEGF reduces astrogliosis and preserves neuromuscular junctions in ALS transgenic mice. , 2007, Biochemical and biophysical research communications.

[26]  Christian Wiesmann,et al.  Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding , 2007, The EMBO journal.

[27]  S. Guthrie,et al.  Patterning and axon guidance of cranial motor neurons , 2007, Nature Reviews Neuroscience.

[28]  K. Mitchell,et al.  Boundary cap cells constrain spinal motor neuron somal migration at motor exit points by a semaphorin-plexin mechanism , 2007, Neural Development.

[29]  B. Traynor,et al.  Genetics of sporadic amyotrophic lateral sclerosis. , 2007, Human molecular genetics.

[30]  L. H. van den Berg,et al.  Lifetime occupation, education, smoking, and risk of ALS , 2007, Neurology.

[31]  P. Monk,et al.  Embryonic stem cells and prospects for their use in regenerative medicine approaches to motor neurone disease , 2007, Neuropathology and applied neurobiology.

[32]  P. Leigh,et al.  Clinical care of patients with amyotrophic lateral sclerosis , 2007, The Lancet Neurology.

[33]  O. Isacson,et al.  REVIEW ARTILCE: Cell therapy and stem cells in animal models of motor neuron disorders , 2007, The European journal of neuroscience.

[34]  M. Granato,et al.  Analysis of zebrafish sidetracked mutants reveals a novel role for Plexin A3 in intraspinal motor axon guidance , 2007, Development.

[35]  W. Shoji,et al.  Novel mutations affecting axon guidance in zebrafish and a role for plexin signalling in the guidance of trigeminal and facial nerve axons , 2007, Development.

[36]  C. Hoogenraad,et al.  Motor Neuron Disease-Associated Mutant Vesicle-Associated Membrane Protein-Associated Protein (VAP) B Recruits Wild-Type VAPs into Endoplasmic Reticulum-Derived Tubular Aggregates , 2007, The Journal of Neuroscience.

[37]  C. Holt,et al.  Local translation and directional steering in axons , 2007, The EMBO journal.

[38]  C. Svendsen,et al.  GDNF Secreting Human Neural Progenitor Cells Protect Dying Motor Neurons, but Not Their Projection to Muscle, in a Rat Model of Familial ALS , 2007, PloS one.

[39]  L. Viera,et al.  Mutant Cu/Zn-Superoxide Dismutase Associated with Amyotrophic Lateral Sclerosis Destabilizes Vascular Endothelial Growth Factor mRNA and Downregulates Its Expression , 2007, The Journal of Neuroscience.

[40]  M. Tessier-Lavigne,et al.  The Nogo-66 Receptor NgR1 Is Required Only for the Acute Growth Cone-Collapsing But Not the Chronic Growth-Inhibitory Actions of Myelin Inhibitors , 2007, The Journal of Neuroscience.

[41]  S. Ackerman,et al.  UNC5C is required for spinal accessory motor neuron development , 2007, Molecular and Cellular Neuroscience.

[42]  J. Hauw,et al.  Muscle Nogo‐a expression is a prognostic marker in lower motor neuron syndromes , 2007, Annals of neurology.

[43]  X. Navarro,et al.  Neural plasticity after peripheral nerve injury and regeneration , 2007, Progress in Neurobiology.

[44]  D. Maraganore,et al.  A Genomic Pathway Approach to a Complex Disease: Axon Guidance and Parkinson Disease , 2007, PLoS genetics.

[45]  G. Rougon,et al.  Semaphorins in development and adult brain: Implication for neurological diseases , 2007, Progress in Neurobiology.

[46]  S. Bissière,et al.  Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells , 2007, Nature Neuroscience.

[47]  J. Feldner,et al.  PlexinA3 Restricts Spinal Exit Points and Branching of Trunk Motor Nerves in Embryonic Zebrafish , 2007, The Journal of Neuroscience.

[48]  R. Klein,et al.  Bidirectional Eph-ephrin signaling during axon guidance. , 2007, Trends in cell biology.

[49]  V. Dietz,et al.  Repair of the Injured Spinal Cord , 2007, Neurodegenerative Diseases.

[50]  O. Marín,et al.  Robo1 and Robo2 Cooperate to Control the Guidance of Major Axonal Tracts in the Mammalian Forebrain , 2007, The Journal of Neuroscience.

[51]  A. Parsadanian,et al.  Muscle-derived but not centrally derived transgene GDNF is neuroprotective in G93A-SOD1 mouse model of ALS , 2007, Experimental Neurology.

[52]  K. Jin,et al.  Vascular Endothelial Growth Factor Overexpression Delays Neurodegeneration and Prolongs Survival in Amyotrophic Lateral Sclerosis Mice , 2007, The Journal of Neuroscience.

[53]  E. Beghi,et al.  The epidemiology of ALS and the role of population-based registries. , 2006, Biochimica et biophysica acta.

[54]  H. Okano,et al.  A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cord , 2006, Nature Medicine.

[55]  M. Schwab,et al.  The neurite outgrowth inhibitor Nogo‐A promotes denervation in an amyotrophic lateral sclerosis model , 2006, EMBO reports.

[56]  E. Kabashi,et al.  Failure of protein quality control in amyotrophic lateral sclerosis. , 2006, Biochimica et biophysica acta.

[57]  U. Greferath,et al.  Eph tyrosine kinase receptor EphA4 is required for the topographic mapping of the corticospinal tract , 2006, Proceedings of the National Academy of Sciences.

[58]  S. Strittmatter,et al.  Extracellular regulators of axonal growth in the adult central nervous system , 2006, Philosophical Transactions of the Royal Society B: Biological Sciences.

[59]  Robert H. Brown,et al.  Molecular biology of amyotrophic lateral sclerosis: insights from genetics , 2006, Nature Reviews Neuroscience.

[60]  P. Carmeliet,et al.  Another angiogenic gene linked to amyotrophic lateral sclerosis. , 2006, Trends in molecular medicine.

[61]  L. Rubin,et al.  Recovery from paralysis in adult rats using embryonic stem cells , 2006, Annals of neurology.

[62]  H. Soreq,et al.  Termination and beyond: acetylcholinesterase as a modulator of synaptic transmission , 2006, Cell and Tissue Research.

[63]  S. Niclou,et al.  The expression of the chemorepellent Semaphorin 3A is selectively induced in terminal Schwann cells of a subset of neuromuscular synapses that display limited anatomical plasticity and enhanced vulnerability in motor neuron disease , 2006, Molecular and Cellular Neuroscience.

[64]  Rüdiger Klein,et al.  Cooperation between GDNF/Ret and ephrinA/EphA4 Signals for Motor-Axon Pathway Selection in the Limb , 2006, Neuron.

[65]  J. Chilton.  Molecular mechanisms of axon guidance. , 2006, Developmental biology.

[66]  H. Kaminski,et al.  Molecular architecture of the neuromuscular junction , 2006, Muscle & nerve.

[67]  L. Rubin,et al.  Motoneurons Derived from Embryonic Stem Cells Express Transcription Factors and Develop Phenotypes Characteristic of Medial Motor Column Neurons , 2006, The Journal of Neuroscience.

[68]  W. Shoji,et al.  Sema3a1 guides spinal motor axons in a cell- and stage-specific manner in zebrafish , 2006, Development.

[69]  Pico Caroni,et al.  Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF , 2006, Nature Neuroscience.

[70]  A. Kolodkin,et al.  MICAL flavoprotein monooxygenases: Expression during neural development and following spinal cord injuries in the rat , 2006, Molecular and Cellular Neuroscience.

[71]  Chenghua Gu,et al.  Distinct Roles for Secreted Semaphorin Signaling in Spinal Motor Axon Guidance , 2005, Neuron.

[72]  R. Coggeshall,et al.  Human neural stem cell-derived cholinergic neurons innervate muscle in motoneuron deficient adult rats , 2005, Neuroscience.

[73]  J. Sanes,et al.  Molecular Control of Spinal Accessory Motor Neuron/Axon Development in the Mouse Spinal Cord , 2005, The Journal of Neuroscience.

[74]  J. Chilton,et al.  Slit-mediated repulsion is a key regulator of motor axon pathfinding in the hindbrain , 2005, Development.

[75]  Jun Shi,et al.  Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract , 2005, Nature Neuroscience.

[76]  P. Shaw,et al.  Molecular and cellular pathways of neurodegeneration in motor neurone disease , 2005, Journal of Neurology, Neurosurgery & Psychiatry.

[77]  Y. Itoyama,et al.  Neuroprotective effect of oxidized galectin-1 in a transgenic mouse model of amyotrophic lateral sclerosis , 2005, Experimental Neurology.

[78]  T. Hunter,et al.  Coexpressed EphA Receptors and Ephrin-A Ligands Mediate Opposing Actions on Growth Cone Navigation from Distinct Membrane Domains , 2005, Cell.

[79]  J. Livet,et al.  A semaphorin code defines subpopulations of spinal motor neurons during mouse development , 2005, The European journal of neuroscience.

[80]  J. Hauw,et al.  Nogo expression in muscle correlates with amyotrophic lateral sclerosis severity , 2005, Annals of neurology.

[81]  J. Steeves,et al.  Altered primary afferent anatomy and reduced thermal sensitivity in mice lacking galectin-1 , 2005, Pain.

[82]  G. Sobue,et al.  Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis , 2005, Annals of neurology.

[83]  Christoph Schmitz,et al.  Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS , 2005, Nature Neuroscience.

[84]  L. Barbeito,et al.  Mitochondria in Amyotrophic Lateral Sclerosis: A Trigger and a Target , 2005, Neurodegenerative Diseases.

[85]  J. Steeves,et al.  Galectin-1 expression correlates with the regenerative potential of rubrospinal and spinal motoneurons , 2004, Neuroscience.

[86]  W. Wang,et al.  Mechanisms underlying the riluzole inhibition of glutamate release from rat cerebral cortex nerve terminals (synaptosomes) , 2004, Neuroscience.

[87]  J. Steeves,et al.  Galectin‐1 in regenerating motoneurons , 2004, The European journal of neuroscience.

[88]  M. C. Bohn,et al.  Motoneurons crave glial cell line-derived neurotrophic factor , 2004, Experimental Neurology.

[89]  P. Wesseling,et al.  Development and malformations of the human pyramidal tract , 2004, Journal of Neurology.

[90]  M. B. Laskowski,et al.  Ephrin-A5 overexpression degrades topographic specificity in the mouse gluteus maximus muscle. , 2004, Brain research. Developmental brain research.

[91]  S. Ennis,et al.  A novel candidate region for ALS on chromosome 14q11.2 , 2004, Neurology.

[92]  A. Kolodkin,et al.  Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve. , 2004, Genes & development.

[93]  T. Gillingwater,et al.  A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis. , 2004, American journal of human genetics.

[94]  R. Keynes,et al.  Somite polarity and segmental patterning of the peripheral nervous system , 2004, Mechanisms of Development.

[95]  P. Carmeliet,et al.  VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model , 2004, Nature.

[96]  J. Rothstein,et al.  Axonal growth of embryonic stem cell-derived motoneurons in vitro and in motoneuron-injured adult rats. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[97]  P. Altevogt,et al.  Brain development in mice lacking L1–L1 homophilic adhesion , 2004, The Journal of cell biology.

[98]  N. Ip,et al.  Identification of the Jak/Stat Proteins as Novel Downstream Targets of EphA4 Signaling in Muscle , 2004, Journal of Biological Chemistry.

[99]  N. Hikawa,et al.  Oxidized Galectin-1 Stimulates Macrophages to Promote Axonal Regeneration in Peripheral Nerves after Axotomy , 2004, The Journal of Neuroscience.

[100]  J. Glass,et al.  Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man , 2004, Experimental Neurology.

[101]  M. Schwab.  Nogo and axon regeneration , 2004, Current Opinion in Neurobiology.

[102]  Marc Tessier-Lavigne,et al.  Anterior-Posterior Guidance of Commissural Axons by Wnt-Frizzled Signaling , 2003, Science.

[103]  A. B. Huber,et al.  Signaling at the growth cone: ligand-receptor complexes and the control of axon growth and guidance. , 2003, Annual review of neuroscience.

[104]  M. Granato,et al.  Motor axon migration: a long way to go. , 2003, Developmental biology.

[105]  L. Olson,et al.  Vascular endothelial growth factor improves functional outcome and decreases secondary degeneration in experimental spinal cord contusion injury , 2003, Neuroscience.

[106]  N. Ip,et al.  Central synapse and neuromuscular junction: same players, different roles. , 2003, Trends in genetics : TIG.

[107]  C. Ko,et al.  Roles of glial cells in the formation, function, and maintenance of the neuromuscular junction , 2003, Journal of neurocytology.

[108]  N. Ip,et al.  Postsynaptic signaling of new players at the neuromuscular junction , 2003, Journal of neurocytology.

[109]  A. Kania,et al.  Topographic Motor Projections in the Limb Imposed by LIM Homeodomain Protein Regulation of Ephrin-A:EphA Interactions , 2003, Neuron.

[110]  S. Strittmatter,et al.  Delayed Systemic Nogo-66 Receptor Antagonist Promotes Recovery from Spinal Cord Injury , 2003, The Journal of Neuroscience.

[111]  S. Tågerud,et al.  Nogo (Reticulon 4) expression in innervated and denervated mouse skeletal muscle , 2003, Molecular and Cellular Neuroscience.

[112]  I. McGonnell,et al.  Integrity of Developing Spinal Motor Columns Is Regulated by Neural Crest Derivatives at Motor Exit Points , 2003, Neuron.

[113]  K. Nave,et al.  The C264Y Missense Mutation in the Extracellular Domain of L1 Impairs Protein Trafficking In Vitro and In Vivo , 2003, The Journal of Neuroscience.

[114]  P. Carmeliet,et al.  VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death , 2003, Nature Genetics.

[115]  C. Haenggeli,et al.  Differential vulnerability of cranial motoneurons in mouse models with motor neuron degeneration , 2002, Neuroscience Letters.

[116]  Jacqueline H. Finger,et al.  The Netrin 1 Receptors Unc5h3 and Dcc Are Necessary at Multiple Choice Points for the Guidance of Corticospinal Tract Axons , 2002, The Journal of Neuroscience.

[117]  N. Yamamoto,et al.  Wiring of the brain by a range of guidance cues , 2002, Progress in Neurobiology.

[118]  Steven A. Crone,et al.  The Bound Leading the Bound Target-Derived Receptors Act as Guidance Cues , 2002, Neuron.

[119]  L. Mckerracher,et al.  Nogo on the Go , 2002, Neuron.

[120]  M. Schwab,et al.  Nogo-A expressed in Schwann cells impairs axonal regeneration after peripheral nerve injury , 2002, The Journal of cell biology.

[121]  S. Arber,et al.  GDNF Acts through PEA3 to Regulate Cell Body Positioning and Muscle Innervation of Specific Motor Neuron Pools , 2002, Neuron.

[122]  V. Meininger,et al.  Nogo Provides a Molecular Marker for Diagnosis of Amyotrophic Lateral Sclerosis , 2002, Neurobiology of Disease.

[123]  Tianyi Mao,et al.  MICALs, a Family of Conserved Flavoprotein Oxidoreductases, Function in Plexin-Mediated Axonal Repulsion , 2002, Cell.

[124]  S. Strittmatter,et al.  Nogo-66 receptor antagonist peptide promotes axonal regeneration , 2002, Nature.

[125]  O. Marín,et al.  Slit Proteins Prevent Midline Crossing and Determine the Dorsoventral Position of Major Axonal Pathways in the Mammalian Forebrain , 2002, Neuron.

[126]  K. Nave,et al.  The C 264 Y Missense Mutation in the Extracellular Domain of L 1 Impairs Protein Trafficking In Vitro and In Vivo , 2002 .

[127]  M. Galea,et al.  Development and reorganization of corticospinal projections in EphA4 deficient mice , 2001, The Journal of comparative neurology.

[128]  S. Guthrie,et al.  Mechanisms and molecules in motor neuron specification and axon pathfinding , 2001, BioEssays : news and reviews in molecular, cellular and developmental biology.

[129]  M. Zimmer,et al.  Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing, allowing for unilateral motor control. , 2001, Genes & development.

[130]  H. Horie,et al.  Galectin-1 is a component of neurofilamentous lesions in sporadic and familial amyotrophic lateral sclerosis. , 2001, Biochemical and biophysical research communications.

[131]  David G. Wilkinson,et al.  Multiple roles of eph receptors and ephrins in neural development , 2001, Nature Reviews Neuroscience.

[132]  K. Kullander,et al.  Kinase-Dependent and Kinase-Independent Functions of EphA4 Receptors in Major Axon Tract Formation In Vivo , 2001, Neuron.

[133]  Mario I. Romero,et al.  Forward Signaling Mediated by Ephrin-B3 Prevents Contralateral Corticospinal Axons from Recrossing the Spinal Cord Midline , 2001, Neuron.

[134]  Till Acker,et al.  Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration , 2001, Nature Genetics.

[135]  T. Jessell.  Neuronal specification in the spinal cord: inductive signals and transcriptional codes , 2000, Nature Reviews Genetics.

[136]  M. Schachner,et al.  Analysis of the L1-Deficient Mouse Phenotype Reveals Cross-Talk between Sema3A and L1 Signaling Pathways in Axonal Guidance , 2000, Neuron.

[137]  J. Alroy,et al.  Favorable effect of VEGF gene transfer on ischemic peripheral neuropathy , 2000, Nature Medicine.

[138]  P. Caroni,et al.  Early and Selective Loss of Neuromuscular Synapse Subtypes with Low Sprouting Competence in Motoneuron Diseases , 2000, The Journal of Neuroscience.

[139]  J. Bolz,et al.  Semaphorins act as attractive and repulsive guidance signals during the development of cortical projections. , 1998, Development.

[140]  A. Ghosh,et al.  Patterning of cortical efferent projections by semaphorin-neuropilin interactions. , 1998, Science.

[141]  M. Nieto,et al.  The expression and regulation of chick EphA7 suggests roles in limb patterning and innervation. , 1998, Development.

[142]  G Paxinos,et al.  EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[143]  R. Guillery,et al.  Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1 , 1998, Current Biology.

[144]  C. Métin,et al.  A role for netrin-1 in the guidance of cortical efferents. , 1997, Development.

[145]  T. Yagi,et al.  Disruption of Semaphorin III/D Gene Causes Severe Abnormality in Peripheral Nerve Projection , 1997, Neuron.

[146]  L. Richards,et al.  Directed Growth of Early Cortical Axons Is Influenced by a Chemoattractant Released from an Intermediate Target , 1997, The Journal of Neuroscience.

[147]  H. Horvitz,et al.  Epidemiology of mutations in superoxide dismutase in amyotrophic lateal sclerosis , 1997, Annals of neurology.

[148]  Hao Wang,et al.  Netrin-1 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System , 1996, Cell.

[149]  M. Hanson,et al.  Hepatocyte Growth Factor/Scatter Factor Is an Axonal Chemoattractant and a Neurotrophic Factor for Spinal Motor Neurons , 1996, Neuron.

[150]  P. Bartlett,et al.  Role of galectin-1 in the developing mouse olfactory system. , 1996, Developmental biology.

[151]  M. Gurney,et al.  Age-Dependent Penetrance of Disease in a Transgenic Mouse Model of Familial Amyotrophic Lateral Sclerosis , 1995, Molecular and Cellular Neuroscience.

[152]  N. Wallace,et al.  Motor unit behavior in canine motor neuron disease , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[153]  D. Buxton,et al.  Differential sites of origin and collateralization of corticospinal neurons in the rat: a multiple fluorescent retrograde tracer study , 1992, Brain Research.

[154]  J. Abbs,et al.  Hypoglossal, trigeminal, and facial motoneuron involvement in amyotrophic lateral sclerosis , 1988, Neurology.