Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.

[1]  S. Yom,et al.  Management of locally recurrent nasopharyngeal carcinoma. , 2019, Cancer treatment reviews.

[2]  Eun-sook Kim,et al.  Tumor-associated macrophages secrete CCL2 and induce the invasive phenotype of human breast epithelial cells through upregulation of ERO1-α and MMP-9. , 2018, Cancer letters.

[3]  Bo Wang,et al.  LNMAT1 promotes lymphatic metastasis of bladder cancer via CCL2 dependent macrophage recruitment , 2018, Nature Communications.

[4]  G. Cao,et al.  CCL2/CCR2 axis induces hepatocellular carcinoma invasion and epithelial-mesenchymal transition in vitro through activation of the Hedgehog pathway , 2017, Oncology reports.

[5]  Jing Wang,et al.  RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non–small Cell Lung Cancer , 2017, Clinical Cancer Research.

[6]  D. Pei,et al.  Rap2a serves as a potential prognostic indicator of renal cell carcinoma and promotes its migration and invasion through up-regulating p-Akt , 2017, Scientific Reports.

[7]  C. Bucci,et al.  Rab7a regulates cell migration through Rac1 and vimentin. , 2017, Biochimica et biophysica acta. Molecular cell research.

[8]  Wei Zhang,et al.  SPINK6 Promotes Metastasis of Nasopharyngeal Carcinoma via Binding and Activation of Epithelial Growth Factor Receptor. , 2017, Cancer research.

[9]  E. Ben-Josef,et al.  Tumor-Derived CCL2 Mediates Resistance to Radiotherapy in Pancreatic Ductal Adenocarcinoma , 2016, Clinical Cancer Research.

[10]  M. Yao,et al.  Elevated expression of chemokine C-C ligand 2 in stroma is associated with recurrent basal-like breast cancers , 2016, Modern Pathology.

[11]  B. Chan,et al.  Outcomes after reirradiation for recurrent nasopharyngeal carcinoma: North American experience , 2016, Head & neck.

[12]  Edwin P Hui,et al.  Nasopharyngeal carcinoma , 2016, The Lancet.

[13]  R. Muschel,et al.  Targeting the CCL2-CCR2 signaling axis in cancer metastasis , 2016, Oncotarget.

[14]  J. Shao,et al.  LOX expression in primary nasopharyngeal carcinoma: correlation with prognostic parameters and outcome , 2016, Oncotarget.

[15]  T. Zeng,et al.  CCL2-CCR2 axis promotes metastasis of nasopharyngeal carcinoma by activating ERK1/2-MMP2/9 pathway , 2015, Oncotarget.

[16]  Kevin J. Harrington,et al.  The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence , 2015, Nature Reviews Cancer.

[17]  Chong Zhao,et al.  Distant metastasis risk and patterns of nasopharyngeal carcinoma in the era of IMRT: long-term results and benefits of chemotherapy , 2015, Oncotarget.

[18]  Chong Zhao,et al.  Prognostic Significance of Tumor Volume in Locally Recurrent Nasopharyngeal Carcinoma Treated with Salvage Intensity-Modulated Radiotherapy , 2015, PloS one.

[19]  Ming Liu,et al.  P-Akt/miR‑200 signaling regulates epithelial-mesenchymal transition, migration and invasion in circulating gastric tumor cells. , 2014, International journal of oncology.

[20]  K. Mertz,et al.  Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis , 2014, Nature.

[21]  High coexpression of CCL2 and CX3CL1 is gender‐specifically associated with good prognosis in soft tissue sarcoma patients , 2014, International journal of cancer.

[22]  Ru-jia Li,et al.  Blocking PI3K/Akt signaling attenuates metastasis of nasopharyngeal carcinoma cells through induction of mesenchymal-epithelial reverting transition. , 2014, Oncology reports.

[23]  D. Meek,et al.  Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters , 2014, Nucleic acids research.

[24]  F. Cheung,et al.  The impact of dosimetric inadequacy on treatment outcome of nasopharyngeal carcinoma with IMRT. , 2014, Oral oncology.

[25]  H. J. Kim,et al.  Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation in cancer-associated fibroblasts , 2014, Oncogene.

[26]  Yong Li,et al.  Emerging roles of radioresistance in prostate cancer metastasis and radiation therapy , 2014, Cancer and Metastasis Reviews.

[27]  Tien-Huang Lin,et al.  CCL2 increases αvβ3 integrin expression and subsequently promotes prostate cancer migration. , 2013, Biochimica et biophysica acta.

[28]  T. Zhu,et al.  Autocrine human GH promotes radioresistance in mammary and endometrial carcinoma cells. , 2012, Endocrine-related cancer.

[29]  H. Sze,et al.  The strength/weakness of the AJCC/UICC staging system (7th edition) for nasopharyngeal cancer and suggestions for future improvement. , 2012, Oral oncology.

[30]  W. Fee,et al.  Nasopharyngeal carcinoma: salvage of local recurrence. , 2012, Oral oncology.

[31]  Xiaoren Tang,et al.  p53 is an important regulator of CCL2 gene expression. , 2012, Current molecular medicine.

[32]  Shiow-Yi Chen,et al.  Autocrine CCL2 promotes cell migration and invasion via PKC activation and tyrosine phosphorylation of paxillin in bladder cancer cells. , 2012, Cytokine.

[33]  Maolan Li,et al.  Vimentin significantly promoted gallbladder carcinoma metastasis. , 2011, Chinese medical journal.

[34]  Yu-Jen Chen,et al.  Sonic hedgehog signaling protects human hepatocellular carcinoma cells against ionizing radiation in an autocrine manner. , 2011, International journal of radiation oncology, biology, physics.

[35]  C. Qian,et al.  The prevalence and prevention of nasopharyngeal carcinoma in China , 2011, Chinese journal of cancer.

[36]  A. Toker,et al.  The actin-bundling protein palladin is an Akt1-specific substrate that regulates breast cancer cell migration. , 2010, Molecular cell.

[37]  H. Kijima,et al.  Vimentin expression of esophageal squamous cell carcinoma and its aggressive potential for lymph node metastasis. , 2010, Biomedical research.

[38]  J. Kurebayashi,et al.  The expression of monocyte chemotactic protein-1 in papillary thyroid carcinoma is correlated with lymph node metastasis and tumor recurrence. , 2009, Thyroid : official journal of the American Thyroid Association.

[39]  H. Prentice-Dunn,et al.  Palladin Contributes to Invasive Motility in Human Breast Cancer Cells , 2008, Oncogene.

[40]  J. Bartek,et al.  Autocrine regulation of glioblastoma cell-cycle progression, viability and radioresistance through the VEGF-VEGFR2 (KDR) interplay , 2008, Cell cycle.

[41]  Y. F. Poon,et al.  Recurrent nasopharyngeal carcinoma: the puzzles of long latency. , 1999, International journal of radiation oncology, biology, physics.

[42]  D. Chua,et al.  Locally recurrent nasopharyngeal carcinoma: treatment results for patients with computed tomography assessment. , 1998, International journal of radiation oncology, biology, physics.

[43]  J. Sham,et al.  The effect of loco-regional control on distant metastatic dissemination in carcinoma of the nasopharynx: an analysis of 1301 patients. , 1994, International journal of radiation oncology, biology, physics.

[44]  Y. F. Poon,et al.  Retrospective analysis of patients with nasopharyngeal carcinoma treated during 1976-1985: survival after local recurrence. , 1993, International journal of radiation oncology, biology, physics.

[45]  D. Shedd,et al.  Metastatic patterns in squamous cell cancer of the head and neck. , 1987, American journal of surgery.

[46]  Pelayo Vilar,et al.  Nasopharyngeal Carcinoma , 1966 .